PE106998A1 - Composiciones oftalmicas - Google Patents
Composiciones oftalmicasInfo
- Publication number
- PE106998A1 PE106998A1 PE1997000898A PE00089897A PE106998A1 PE 106998 A1 PE106998 A1 PE 106998A1 PE 1997000898 A PE1997000898 A PE 1997000898A PE 00089897 A PE00089897 A PE 00089897A PE 106998 A1 PE106998 A1 PE 106998A1
- Authority
- PE
- Peru
- Prior art keywords
- ophthalmic compositions
- glaucoma
- treatment
- acceptable salt
- xanthan gum
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 229940122072 Carbonic anhydrase inhibitor Drugs 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 206010030043 Ocular hypertension Diseases 0.000 abstract 1
- 239000003489 carbonate dehydratase inhibitor Substances 0.000 abstract 1
- 239000000815 hypotonic solution Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 229920001285 xanthan gum Polymers 0.000 abstract 1
- 229940082509 xanthan gum Drugs 0.000 abstract 1
- 235000010493 xanthan gum Nutrition 0.000 abstract 1
- 239000000230 xanthan gum Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
QUE COMPRENDE UNA SOLUCION HIPOTONICA DE: A) 0,1% A 2 % DE GOMA DE XANTANO; Y B) 0,5% A 5% DE UN INHIBIDOR TOPICO DE LA CARBONICO ANHIDRASA DE FORMULA (I), UN DIASTEREOMERO INDIVIDUAL, UN ENANTIOMERO INDIVIDUAL O UNA MEZCLA DE LOS MISMOS, O UNA SAL OFTALMOLOGICAMENTE ACEPTABLE DE LOS MISMOS, DONDE A ES CARBONO O NITROGENO; Z ES -NHR U -OR; R ES ALQUILO C1-C6, DE CADENA LINEAL O RAMIFICADA; R1 ES HIDROGENO, ALQUILO C1-C3 O ALCOXI C1-C4; Y X ES -SO2- o -C(O)-. DICHA COMPOSICION COMPRENDE ADICIONALMENTE APROXIMADAMENTE DE 0,01% A 1% DE UN AGENTE BLOQUEANTE DE RECEPTORES �-ADRENERGENICOS O DE UNA SAL OFTALMOLOGICAMENTE ACEPTABLE DEL MISMO. SE REFIERE TAMBIEN A UN PROCEDIMIENTO PARA TRATAR LA HIPERTENSION OCULAR O EL GLAUCOMA, QUE COMPRENDE LA ADMINISTRACION OCULAR TOPICA, A UN PACIENTE QUE NECESITE DICHO TRATAMIENTO, DE UNA DOSIS UNITARIA DE LA COMPOSICION DESCRITA ANTERIORMEMTE
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9612658A FR2754712B1 (fr) | 1996-10-17 | 1996-10-17 | Compositions ophtalmiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE106998A1 true PE106998A1 (es) | 1999-01-23 |
Family
ID=9496748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1997000898A PE106998A1 (es) | 1996-10-17 | 1997-10-10 | Composiciones oftalmicas |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6264935B1 (es) |
| EP (1) | EP0932389B1 (es) |
| JP (1) | JP2001508035A (es) |
| AT (1) | ATE223200T1 (es) |
| AU (1) | AU715223B2 (es) |
| CA (1) | CA2269552A1 (es) |
| DE (1) | DE69715228T2 (es) |
| ES (1) | ES2183148T3 (es) |
| FR (1) | FR2754712B1 (es) |
| HR (1) | HRP970552A2 (es) |
| PE (1) | PE106998A1 (es) |
| WO (1) | WO1998017249A1 (es) |
| ZA (1) | ZA979219B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6174524B1 (en) | 1999-03-26 | 2001-01-16 | Alcon Laboratories, Inc. | Gelling ophthalmic compositions containing xanthan gum |
| US6261547B1 (en) | 1998-04-07 | 2001-07-17 | Alcon Manufacturing, Ltd. | Gelling ophthalmic compositions containing xanthan gum |
| JP2003513046A (ja) | 1999-11-01 | 2003-04-08 | アルコン，インコーポレイテッド | フルオロキノロン抗生薬およびキサンタンガムを含有する薬学的組成物 |
| EP1305033B1 (en) | 2000-07-28 | 2004-10-20 | Alcon, Inc | Pharmaceutical compositions containing tobramycin and xanthan gum |
| US20040067992A1 (en) * | 2001-08-10 | 2004-04-08 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and a carbonic anhydrase inhibitor for the treatment of neoplasia |
| PL373433A1 (en) * | 2002-08-30 | 2005-08-22 | Altana Pharma Ag | The use of the combination of ciclesonide and antihistamines for the treatment of allergic rhinitis |
| WO2004052374A1 (en) * | 2002-12-12 | 2004-06-24 | Altana Pharma Ag | Combination medicament |
| PL1670482T5 (pl) * | 2003-09-16 | 2022-10-03 | Covis Pharma Gmbh | Zastosowanie cyklezonidu w leczeniu chorób układu oddechowego |
| EP1740188A1 (en) * | 2004-04-20 | 2007-01-10 | Altana Pharma AG | Use of ciclesonide for the treatment of respiratory diseases in a smoking patient |
| CN101031310B (zh) | 2004-09-28 | 2010-10-27 | 千寿制药株式会社 | 含有黄原胶和氨基酸的眼科用组合物 |
| CN101212960B (zh) * | 2005-07-11 | 2011-04-13 | 千寿制药株式会社 | 包括黄原胶和萜类化合物的滴眼制剂 |
| EP1978926A2 (en) * | 2005-12-19 | 2008-10-15 | Comentis, Inc. | Topical mecamylamine formulations for ocular administration and uses thereof |
| EP2002841A4 (en) | 2006-03-23 | 2009-04-15 | Senju Pharma Co | OPHTHALMIC COMPOSITION WITH XANTHANGUMMI AND GLUCOSE |
| EP2050449A4 (en) | 2006-07-31 | 2010-10-06 | Senju Pharma Co | AQUEOUS LIQUID PREPARATION WITH AN AMID COMPOUND |
| EP2309980A1 (en) * | 2008-07-08 | 2011-04-20 | S.I.F.I. Societa' Industria Farmaceutica Italiana | Ophthalmic compositions for treating pathologies of the posterior segment of the eye |
| CA2930113A1 (en) * | 2013-11-15 | 2015-05-21 | Teva Pharmaceutical Industries Ltd. | Treatment of glaucoma using laquinimod |
| UA124698C2 (uk) * | 2014-10-20 | 2021-11-03 | Сентіс Фарма Прайвет Лімітед | Офтальмологічний розчин |
| IT202000002296A1 (it) * | 2020-02-06 | 2021-08-06 | Sifi Spa | Formulazioni topiche oftalmiche a base di xantano con ridotta posologia |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4136173A (en) | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Mixed xanthan gum and locust beam gum therapeutic compositions |
| US4136178A (en) | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Locust bean gum therapeutic compositions |
| US4136177A (en) | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Xanthan gum therapeutic compositions |
| US5157044A (en) | 1983-02-04 | 1992-10-20 | University Of Iowa Research Foundation | Analogs of carbonic anhydrase inhibitors and their use as topical IOP inhibitors |
| US4863922A (en) | 1984-12-12 | 1989-09-05 | Merck & Co., Inc. | Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| US4876271A (en) | 1988-12-20 | 1989-10-24 | Merck & Co., Inc. | Substituted thieno[3,2-b]thiophene-2-sulfonamides as topically active carbonic anhydrase inhibitors |
| US4929549A (en) | 1989-02-08 | 1990-05-29 | Merck & Co., Inc. | 5-carbamoylthieno[2,3-b]thiophene-2-sulfon-amides as topically active carbonic anhydrase inhibitors |
| US5120757A (en) | 1989-07-31 | 1992-06-09 | Merck & Co., Inc. | Substituted aromatic sulfonamides as antiglaucoma agents |
| FR2657018A1 (fr) | 1990-01-12 | 1991-07-19 | Merck Sharp & Dohme | Composition ophtalmique fluide a base de microparticules lipidiques contenant au moins un principe actif et son procede de preparation. |
| US5055480A (en) | 1990-03-19 | 1991-10-08 | Research Corporation Technologies, Inc. | Topically active ocular gem-diacylthiadiazole sulfonamide carbonic anhydrase inhibitors |
| US5242937A (en) | 1990-03-19 | 1993-09-07 | Research Corporation Technologies, Inc. | Topically active ocular thiadiazole sulfonamide carbonic anhydrase inhibitors |
| US5059613A (en) | 1990-03-19 | 1991-10-22 | Research Corporation Technologies, Inc. | Topically active ocular benzothiazole sulfonamide carbonic anhydrase inhibitors |
| IE911192A1 (en) | 1990-04-12 | 1991-10-23 | Merck & Co Inc | Substituted aromatic sulfonamides as antiglaucoma agents |
| CA2040460C (en) | 1990-05-01 | 1997-06-10 | Tacey X. Viegas | Drug delivery with thermoreversible gels |
| US5091409A (en) | 1990-05-17 | 1992-02-25 | Merck & Co., Inc. | 4-alkylamino-6-(C3-5 -hydrocarbyl)thieno[2,3-B]thiopyran-2-sulfonamide-7,7-dioxides |
| US5093332A (en) | 1990-10-01 | 1992-03-03 | Merck & Co., Inc. | Substituted thieno(2,3-b)(1,4)thiazine-6-sulfonamides as antiglaucoma agents |
| EP0495421B1 (en) | 1991-01-15 | 1996-08-21 | Alcon Laboratories, Inc. | Use of carrageenans in topical ophthalmic compositions |
| JP2536806B2 (ja) * | 1991-03-27 | 1996-09-25 | アルコン ラボラトリーズ インコーポレイテッド | ゲル化多糖類と微粉砕された薬剤担体とを組み合わせた局部眼科用組成物 |
| US5318780A (en) * | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
| WO1994006411A1 (en) | 1992-09-17 | 1994-03-31 | Alcon Laboratories, Inc. | Topical carbonic anhydrase inhibitor composition |
| SE9301877D0 (sv) * | 1993-06-02 | 1993-06-02 | Kabi Pharmacia Ab | In situ gel for therapeutic use |
| WO2000004899A1 (en) * | 1998-07-21 | 2000-02-03 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
-
1996
- 1996-10-17 FR FR9612658A patent/FR2754712B1/fr not_active Expired - Fee Related
-
1997
- 1997-10-09 AT AT97911223T patent/ATE223200T1/de not_active IP Right Cessation
- 1997-10-09 CA CA002269552A patent/CA2269552A1/en not_active Abandoned
- 1997-10-09 AU AU48673/97A patent/AU715223B2/en not_active Ceased
- 1997-10-09 EP EP97911223A patent/EP0932389B1/en not_active Expired - Lifetime
- 1997-10-09 ES ES97911223T patent/ES2183148T3/es not_active Expired - Lifetime
- 1997-10-09 JP JP51891698A patent/JP2001508035A/ja active Pending
- 1997-10-09 WO PCT/EP1997/005678 patent/WO1998017249A1/en not_active Ceased
- 1997-10-09 US US09/284,718 patent/US6264935B1/en not_active Expired - Fee Related
- 1997-10-09 DE DE69715228T patent/DE69715228T2/de not_active Expired - Fee Related
- 1997-10-10 PE PE1997000898A patent/PE106998A1/es not_active Application Discontinuation
- 1997-10-15 ZA ZA979219A patent/ZA979219B/xx unknown
- 1997-10-16 HR HR9612658A patent/HRP970552A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU715223B2 (en) | 2000-01-20 |
| AU4867397A (en) | 1998-05-15 |
| EP0932389A1 (en) | 1999-08-04 |
| ATE223200T1 (de) | 2002-09-15 |
| JP2001508035A (ja) | 2001-06-19 |
| CA2269552A1 (en) | 1998-04-30 |
| US6264935B1 (en) | 2001-07-24 |
| WO1998017249A1 (en) | 1998-04-30 |
| ES2183148T3 (es) | 2003-03-16 |
| FR2754712B1 (fr) | 1999-09-03 |
| HRP970552A2 (en) | 1998-08-31 |
| DE69715228T2 (de) | 2003-06-05 |
| FR2754712A1 (fr) | 1998-04-24 |
| ZA979219B (en) | 1998-07-17 |
| EP0932389B1 (en) | 2002-09-04 |
| DE69715228D1 (de) | 2002-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |