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PA8446001A1 - N-HYDROXY-B-SULPHONYL PROPIONAMIDE DERIVATIVES - Google Patents

N-HYDROXY-B-SULPHONYL PROPIONAMIDE DERIVATIVES

Info

Publication number
PA8446001A1
PA8446001A1 PA19988446001A PA8446001A PA8446001A1 PA 8446001 A1 PA8446001 A1 PA 8446001A1 PA 19988446001 A PA19988446001 A PA 19988446001A PA 8446001 A PA8446001 A PA 8446001A PA 8446001 A1 PA8446001 A1 PA 8446001A1
Authority
PA
Panama
Prior art keywords
sulphonyl
hydroxy
derivatives
propionamide derivatives
propionamide
Prior art date
Application number
PA19988446001A
Other languages
Spanish (es)
Inventor
Ralph Pelton
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PA8446001A1 publication Critical patent/PA8446001A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

ESTA INVENCION SE REFIERE A DERIVADOS DEL ACIDO ARILSULFONILAMINO HIDROXAMICO QUE SON INHIBIDORES DE LAS METALOPROTEINASAS DE LA MATRIZ O DE LA PRODUCCION DEL FACTOR DE NECROSISTUMORAL (TNF) Y EN COMPUESTO DE FORMULA EN LA QUE R1,R2,R3, R4 Y Q SON TAL COMO SE DEFINE EN LA DESCRIPCION, COMPOSICIONES FARMACEUTICAS QUE LO CONTIENEN Y SU USO MEDICINAL.THIS INVENTION IS RELATED TO DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO THAT ARE INHIBITORS OF THE METALOPROTEINASAS OF THE MATRIX OR OF THE PRODUCTION OF THE NECROSISTUMORAL FACTOR (TNF) AND IN A COMPOUND OF FORMULA IN WHICH R1, R2, R3, R4 DEFINE IN THE DESCRIPTION, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT AND ITS MEDICINAL USE.

PA19988446001A 1997-02-07 1998-02-08 N-HYDROXY-B-SULPHONYL PROPIONAMIDE DERIVATIVES PA8446001A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3740297P 1997-02-07 1997-02-07

Publications (1)

Publication Number Publication Date
PA8446001A1 true PA8446001A1 (en) 2000-05-24

Family

ID=21894150

Family Applications (1)

Application Number Title Priority Date Filing Date
PA19988446001A PA8446001A1 (en) 1997-02-07 1998-02-08 N-HYDROXY-B-SULPHONYL PROPIONAMIDE DERIVATIVES

Country Status (13)

Country Link
EP (1) EP0966438A1 (en)
JP (1) JP2000507975A (en)
AP (1) AP9801169A0 (en)
AR (1) AR011116A1 (en)
AU (1) AU5493598A (en)
BR (1) BR9807824A (en)
CA (1) CA2279863A1 (en)
HR (1) HRP980062A2 (en)
MA (1) MA26472A1 (en)
PA (1) PA8446001A1 (en)
TN (1) TNSN98022A1 (en)
WO (1) WO1998034915A1 (en)
ZA (1) ZA98970B (en)

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