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LV15619A - Paņēmiens bioloģiski aktīvu savienojumu saistīšanas afinitātes pret kardiolipīnu noteikšanai - Google Patents

Paņēmiens bioloģiski aktīvu savienojumu saistīšanas afinitātes pret kardiolipīnu noteikšanai

Info

Publication number
LV15619A
LV15619A LVP-20-56A LVP2020000056A LV15619A LV 15619 A LV15619 A LV 15619A LV P2020000056 A LVP2020000056 A LV P2020000056A LV 15619 A LV15619 A LV 15619A
Authority
LV
Latvia
Prior art keywords
cardiolipin
biologically active
binding affinity
active compounds
measuring binding
Prior art date
Application number
LVP-20-56A
Other languages
English (en)
Inventor
Pāvels ARSENJANS
Pāvels DIMITRIJEVS
Original Assignee
Latvijas Organiskās Sintēzes Institūts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Latvijas Organiskās Sintēzes Institūts filed Critical Latvijas Organiskās Sintēzes Institūts
Priority to LVP-20-56A priority Critical patent/LV15619A/lv
Priority to CN202180055484.8A priority patent/CN116097101B/zh
Priority to PCT/IB2021/054479 priority patent/WO2022038424A1/en
Priority to US18/011,916 priority patent/US20230243840A1/en
Priority to EP21731588.6A priority patent/EP4200609B1/en
Publication of LV15619A publication Critical patent/LV15619A/lv

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6827—Total protein determination, e.g. albumin in urine
    • G01N33/683—Total protein determination, e.g. albumin in urine involving metal ions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Šis izgudrojums attiecas uz metodi, lai noteiktu bioloģiski aktīvo vielu saistīšanos ar kardiolipīnu, balstoties uz akridīnija sāls izmantošanu kā fluorescentu zondi.
LVP-20-56A 2020-08-20 2020-08-20 Paņēmiens bioloģiski aktīvu savienojumu saistīšanas afinitātes pret kardiolipīnu noteikšanai LV15619A (lv)

Priority Applications (5)

Application Number Priority Date Filing Date Title
LVP-20-56A LV15619A (lv) 2020-08-20 2020-08-20 Paņēmiens bioloģiski aktīvu savienojumu saistīšanas afinitātes pret kardiolipīnu noteikšanai
CN202180055484.8A CN116097101B (zh) 2020-08-20 2021-05-24 用于测量生物活性化合物对心磷脂的结合亲和力的测定法
PCT/IB2021/054479 WO2022038424A1 (en) 2020-08-20 2021-05-24 An assay for measuring binding affinity for cardiolipin of biologically active compounds
US18/011,916 US20230243840A1 (en) 2020-08-20 2021-05-24 An assay for measuring binding affinity for cardiolipin of biologically active compounds
EP21731588.6A EP4200609B1 (en) 2020-08-20 2021-05-24 An assay for measuring binding affinity for cardiolipin of biologically active compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LVP-20-56A LV15619A (lv) 2020-08-20 2020-08-20 Paņēmiens bioloģiski aktīvu savienojumu saistīšanas afinitātes pret kardiolipīnu noteikšanai

Publications (1)

Publication Number Publication Date
LV15619A true LV15619A (lv) 2022-02-20

Family

ID=80350393

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-20-56A LV15619A (lv) 2020-08-20 2020-08-20 Paņēmiens bioloģiski aktīvu savienojumu saistīšanas afinitātes pret kardiolipīnu noteikšanai

Country Status (5)

Country Link
US (1) US20230243840A1 (lv)
EP (1) EP4200609B1 (lv)
CN (1) CN116097101B (lv)
LV (1) LV15619A (lv)
WO (1) WO2022038424A1 (lv)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2021262A (en) * 1978-05-16 1979-11-28 Syva Co Protein binding assays
CN107807238A (zh) * 2016-06-30 2018-03-16 深圳市亚辉龙生物科技股份有限公司 抗心磷脂抗体化学发光免疫检测试剂盒及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1276833B1 (it) * 1995-10-09 1997-11-03 Sorin Biomedica Cardio Spa Coloranti fluorescenti della famiglia della solfo benz e indocianina
EE200600030A (et) * 2006-08-15 2008-04-15 Tartu �likool Proteiinkinaasi fluorestsents-sond
LV15576A (lv) * 2019-11-28 2021-06-20 Latvijas Organiskās Sintēzes Institūts Fluorescējošie akridīnija sāļi, to sintēze un izmantošana kardiolipīna noteikšanai

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2021262A (en) * 1978-05-16 1979-11-28 Syva Co Protein binding assays
CN107807238A (zh) * 2016-06-30 2018-03-16 深圳市亚辉龙生物科技股份有限公司 抗心磷脂抗体化学发光免疫检测试剂盒及其制备方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KAEWSUYA P ET AL: "Fluorescent determination of cardiolipin using 10-N-nonyl acridine orange", ANALYTICAL AND BIOANALYTICAL CHEMISTRY, SPRINGER, BERLIN, DE, vol. 387, no. 8, 15 February 2007 (2007-02-15), pages 2775 - 2782, XP019488817, ISSN: 1618-2650, DOI: 10.1007/S00216-007-1135-0 *

Also Published As

Publication number Publication date
EP4200609A1 (en) 2023-06-28
CN116097101A (zh) 2023-05-09
US20230243840A1 (en) 2023-08-03
EP4200609C0 (en) 2023-12-27
CN116097101B (zh) 2025-09-16
EP4200609B1 (en) 2023-12-27
WO2022038424A1 (en) 2022-02-24

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