LV12686B - Diabeta arstesanas panemiens izmantojot ap2 inhibitoru un to saturosas kombinacijas - Google Patents

Diabeta arstesanas panemiens izmantojot ap2 inhibitoru un to saturosas kombinacijas

Info

Publication number: LV12686B
Authority: LV; Latvia
Prior art keywords: combination; inhibitor; content; diabetes treatment; pravastatin
Prior art date: 1998-09-17

Application number

LV010057A

Other languages

English (en)

Other versions

LV12686A (lv

Inventor

Jeffrey Robl

Rex A Parker

Scott A Biller

Haris Jamil

Bruce L Jacobson

Krishna Kodukula

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-17

Filing date

2001-04-12

Publication date

2001-10-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22280975&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV12686(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-04-12 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2001-07-20 Publication of LV12686A publication Critical patent/LV12686A/lv

2001-10-20 Publication of LV12686B publication Critical patent/LV12686B/lv

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Obesity (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Child & Adolescent Psychology (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Steroid Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)

LV010057A 1998-09-17 2001-04-12 Diabeta arstesanas panemiens izmantojot ap2 inhibitoru un to saturosas kombinacijas LV12686B (lv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10067798P	1998-09-17	1998-09-17
PCT/US1999/020946 WO2000015229A1 (en)	1998-09-17	1999-09-13	METHOD FOR TREATING DIABETES EMPLOYING AN aP2 INHIBITOR AND COMBINATION

Publications (2)

Publication Number	Publication Date
LV12686A LV12686A (lv)	2001-07-20
LV12686B true LV12686B (lv)	2001-10-20

Family

ID=22280975

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
LV010057A LV12686B (lv)	1998-09-17	2001-04-12	Diabeta arstesanas panemiens izmantojot ap2 inhibitoru un to saturosas kombinacijas
LV010058A LV12687B (lv)	1998-09-17	2001-04-12	Aterosklerozes arstesanas panemiens izmantojot ap2 inhibitoru un to saturosas kombinacijas

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
LV010058A LV12687B (lv)	1998-09-17	2001-04-12	Aterosklerozes arstesanas panemiens izmantojot ap2 inhibitoru un to saturosas kombinacijas

Country Status (30)

Country	Link
US (1)	US20020035064A1 (lv)
EP (2)	EP1121129B1 (lv)
JP (2)	JP2002524517A (lv)
KR (2)	KR20010079842A (lv)
CN (2)	CN1319012A (lv)
AT (1)	ATE406898T1 (lv)
AU (2)	AU754488B2 (lv)
BG (2)	BG105431A (lv)
BR (2)	BR9913831A (lv)
CA (2)	CA2344309A1 (lv)
CO (2)	CO5130026A1 (lv)
CZ (2)	CZ2001965A3 (lv)
DE (1)	DE69939481D1 (lv)
EE (2)	EE200100155A (lv)
ES (1)	ES2311306T3 (lv)
GE (2)	GEP20033045B (lv)
HU (2)	HUP0104240A2 (lv)
ID (2)	ID28450A (lv)
IL (2)	IL141785A0 (lv)
LT (2)	LT4870B (lv)
LV (2)	LV12686B (lv)
NO (2)	NO20011352L (lv)
NZ (2)	NZ510209A (lv)
PE (2)	PE20001056A1 (lv)
PL (2)	PL346660A1 (lv)
SK (1)	SK3202001A3 (lv)
TR (2)	TR200100773T2 (lv)
UY (2)	UY25714A1 (lv)
WO (2)	WO2000015229A1 (lv)
ZA (2)	ZA200207430B (lv)

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JP6223376B2 (ja) *	2014-03-24	2017-11-01	花王株式会社	Ｇｉｐ上昇抑制剤の評価又は選択方法
JP6514282B2 (ja) *	2014-03-24	2019-05-15	花王株式会社	Ｇｉｐ上昇抑制剤の評価又は選択方法
BR112017023158A2 (pt)	2015-04-30	2018-07-24	Harvard College	anticorpos anti-ap2 e agentes de ligação de antígeno para tratar distúrbios metabólicos
EP3475299A4 (en) *	2016-06-27	2020-03-18	President and Fellows of Harvard College	CONNECTIONS FOR TREATING METABOLISM DISORDERS
CA3066733A1 (en)	2017-06-09	2018-12-13	President And Fellows Of Harvard College	Method to identify compounds useful to treat dysregulated lipogenesis, diabetes, and related disorders
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1999
- 1999-09-13 DE DE69939481T patent/DE69939481D1/de not_active Revoked
- 1999-09-13 IL IL14178599A patent/IL141785A0/xx unknown
- 1999-09-13 GE GEAP19995860A patent/GEP20033045B/en unknown
- 1999-09-13 CA CA002344309A patent/CA2344309A1/en not_active Abandoned
- 1999-09-13 AU AU63877/99A patent/AU754488B2/en not_active Ceased
- 1999-09-13 NZ NZ510209A patent/NZ510209A/en unknown
- 1999-09-13 CZ CZ2001965A patent/CZ2001965A3/cs unknown
- 1999-09-13 KR KR1020017003408A patent/KR20010079842A/ko not_active Withdrawn
- 1999-09-13 KR KR1020017003411A patent/KR20010075150A/ko not_active Withdrawn
- 1999-09-13 GE GEAP19995861A patent/GEP20033044B/en unknown
- 1999-09-13 HU HU0104240A patent/HUP0104240A2/hu unknown
- 1999-09-13 EE EEP200100155A patent/EE200100155A/xx unknown
- 1999-09-13 SK SK320-2001A patent/SK3202001A3/sk unknown
- 1999-09-13 AU AU61437/99A patent/AU755563B2/en not_active Ceased
- 1999-09-13 CN CN99811096A patent/CN1319012A/zh active Pending
- 1999-09-13 ES ES99951438T patent/ES2311306T3/es not_active Expired - Lifetime
- 1999-09-13 EP EP99951438A patent/EP1121129B1/en not_active Revoked
- 1999-09-13 ID IDW20010624A patent/ID28450A/id unknown
- 1999-09-13 NZ NZ510207A patent/NZ510207A/en unknown
- 1999-09-13 WO PCT/US1999/020946 patent/WO2000015229A1/en not_active Ceased
- 1999-09-13 BR BR9913831-0A patent/BR9913831A/pt not_active IP Right Cessation
- 1999-09-13 CA CA002344300A patent/CA2344300A1/en not_active Abandoned
- 1999-09-13 EE EEP200100154A patent/EE04356B1/xx not_active IP Right Cessation
- 1999-09-13 JP JP2000569813A patent/JP2002524517A/ja active Pending
- 1999-09-13 EP EP99948210A patent/EP1113801A4/en not_active Withdrawn
- 1999-09-13 TR TR2001/00773T patent/TR200100773T2/xx unknown
- 1999-09-13 PL PL99346660A patent/PL346660A1/xx not_active Application Discontinuation
- 1999-09-13 CN CN99811000A patent/CN1317970A/zh active Pending
- 1999-09-13 HU HU0104108A patent/HUP0104108A2/hu unknown
- 1999-09-13 TR TR2001/00774T patent/TR200100774T2/xx unknown
- 1999-09-13 JP JP2000569814A patent/JP2002524518A/ja active Pending
- 1999-09-13 ID IDW20010626A patent/ID27833A/id unknown
- 1999-09-13 BR BR9913833-6A patent/BR9913833A/pt not_active IP Right Cessation
- 1999-09-13 CZ CZ2001964A patent/CZ2001964A3/cs unknown
- 1999-09-13 PL PL99346661A patent/PL346661A1/xx unknown
- 1999-09-13 AT AT99951438T patent/ATE406898T1/de not_active IP Right Cessation
- 1999-09-13 IL IL14178699A patent/IL141786A0/xx unknown
- 1999-09-13 WO PCT/US1999/021069 patent/WO2000015230A1/en not_active Ceased
- 1999-09-15 CO CO99058376A patent/CO5130026A1/es unknown
- 1999-09-15 CO CO99058374A patent/CO5130025A1/es unknown
- 1999-09-16 UY UY25714A patent/UY25714A1/es unknown
- 1999-09-16 UY UY25713A patent/UY25713A1/es unknown
- 1999-09-17 PE PE1999000943A patent/PE20001056A1/es not_active Application Discontinuation
- 1999-09-17 PE PE1999000944A patent/PE20001047A1/es not_active Application Discontinuation
2001
- 2001-03-16 LT LT2001023A patent/LT4870B/lt not_active IP Right Cessation
- 2001-03-16 NO NO20011352A patent/NO20011352L/no not_active Application Discontinuation
- 2001-03-16 LT LT2001022A patent/LT4871B/lt not_active IP Right Cessation
- 2001-03-16 NO NO20011351A patent/NO20011351L/no unknown
- 2001-04-10 BG BG105431A patent/BG105431A/xx unknown
- 2001-04-10 BG BG105432A patent/BG105432A/xx unknown
- 2001-04-12 LV LV010057A patent/LV12686B/lv unknown
- 2001-04-12 LV LV010058A patent/LV12687B/lv unknown
- 2001-07-13 US US09/905,235 patent/US20020035064A1/en not_active Abandoned
2002
- 2002-09-16 ZA ZA200207430A patent/ZA200207430B/en unknown
- 2002-09-16 ZA ZA200207433A patent/ZA200207433B/en unknown

Also Published As

Publication number	Publication date
EE04356B1 (et)	2004-10-15
TR200100773T2 (tr)	2001-07-23
HUP0104240A2 (hu)	2002-03-28
NO20011351D0 (no)	2001-03-16
WO2000015230A1 (en)	2000-03-23
PE20001056A1 (es)	2000-12-24
BG105432A (en)	2001-12-29
EP1113801A4 (en)	2002-10-02
LV12686A (lv)	2001-07-20
ID28450A (id)	2001-05-24
GEP20033044B (en)	2003-08-25
GEP20033045B (en)	2003-08-25
PL346661A1 (en)	2002-02-25
KR20010075150A (ko)	2001-08-09
EP1121129A4 (en)	2002-10-16
CZ2001964A3 (cs)	2002-01-16
KR20010079842A (ko)	2001-08-22
NO20011352L (no)	2001-05-11
JP2002524518A (ja)	2002-08-06
LT4870B (lt)	2001-12-27
AU755563B2 (en)	2002-12-12
BR9913831A (pt)	2001-05-29
LT4871B (lt)	2001-12-27
TR200100774T2 (tr)	2001-12-21
LV12687A (lv)	2001-07-20
EP1121129A1 (en)	2001-08-08
ZA200207433B (en)	2003-10-27
IL141786A0 (en)	2002-03-10
AU6143799A (en)	2000-04-03
ES2311306T3 (es)	2009-02-01
CN1319012A (zh)	2001-10-24
HUP0104108A2 (hu)	2002-03-28
CO5130026A1 (es)	2002-02-27
PL346660A1 (en)	2002-02-25
WO2000015229A1 (en)	2000-03-23
CZ2001965A3 (cs)	2002-02-13
CA2344300A1 (en)	2000-03-23
AU754488B2 (en)	2002-11-14
EE200100154A (et)	2002-12-16
NO20011351L (no)	2001-05-11
UY25713A1 (es)	2001-08-27
NZ510207A (en)	2003-08-29
UY25714A1 (es)	2001-08-27
NZ510209A (en)	2003-07-25
BG105431A (en)	2001-12-29
ZA200207430B (en)	2003-09-16
ATE406898T1 (de)	2008-09-15
CO5130025A1 (es)	2002-02-27
DE69939481D1 (de)	2008-10-16
LV12687B (lv)	2001-10-20
EP1121129B1 (en)	2008-09-03
EP1113801A1 (en)	2001-07-11
LT2001023A (en)	2001-08-27
CA2344309A1 (en)	2000-03-23
ID27833A (id)	2001-04-26
EE200100155A (et)	2002-08-15
CN1317970A (zh)	2001-10-17
JP2002524517A (ja)	2002-08-06
BR9913833A (pt)	2001-05-29
PE20001047A1 (es)	2000-12-24
US20020035064A1 (en)	2002-03-21
IL141785A0 (en)	2002-03-10
SK3202001A3 (en)	2002-04-04
NO20011352D0 (no)	2001-03-16
AU6387799A (en)	2000-04-03
LT2001022A (en)	2001-08-27

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EA200200105A1 (ru)	2002-06-27	СОЕДИНЕНИЯ, МОДУЛИРУЮЩИЕ АКТИВНОСТЬ PPARγ;
BR9714364A (pt)	2000-03-21	Amidas inibidoras da secreção de apo b/mtp
BR9707081A (pt)	1999-05-25	Soluções de injeção e infusão concentradas aperfeiçoadas para aplicação intravasal
WO2000061167A3 (en)	2001-01-11	TREATMENT OF MYELOMA BONE DISEASE WITH PROTEASOMAL AND NF-λB ACTIVITY INHIBITORS
AU2001262401A1 (en)	2001-11-26	Use of ellagic acid as anti-pollution cosmetic agent
DE3881373D1 (de)	1993-07-01	Hmg-coa-reduktase-hemmer.
AP9801261A0 (en)	1999-12-11	Farnesyl transferase inhibitors in combination with HMG COA reductase inhibitors for the treatment of cancer.
DE68900988D1 (de)	1992-04-23	Hmg-coa-reduktase-inhibitoren.
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SE9302208L (sv)	1994-12-29	Sätt vid dekontaminering
NO963989D0 (no)	1996-09-23	Hypokolesterolemiske-, antiatherosklerotiske- og hypotriglyceridemiske mercaptoacetylamidderivater
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ES2113647T3 (es)	1998-05-01	Composicion.
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AU2002366442A1 (en)	2003-06-30	Screening method for agents useful in treating diabetes
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