LTC2068874I2 - Dauginės mielomos, naudojant kombinuotas terapijas, pagrįstas anti-CS1 antikūnais, gydymo būdai - Google Patents

Dauginės mielomos, naudojant kombinuotas terapijas, pagrįstas anti-CS1 antikūnais, gydymo būdai

Info

Publication number: LTC2068874I2
Authority: LT; Lithuania
Prior art keywords: antibodies; methods; multiple myeloma; combination therapies; treating multiple
Prior art date: 2006-08-07

Application number

LTPA2016031C

Other languages

English (en)

Original Assignee

Abbvie Biotherapeutics Inc.

Dana-Farber Cancer Institute, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-08-07

Filing date

2016-10-27

Publication date

2018-11-12

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38831279&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LTC2068874(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2016-10-27 Application filed by Abbvie Biotherapeutics Inc., Dana-Farber Cancer Institute, Inc. filed Critical Abbvie Biotherapeutics Inc.

2016-11-10 Publication of LTPA2016031I1 publication Critical patent/LTPA2016031I1/lt

2018-11-12 Publication of LTC2068874I2 publication Critical patent/LTC2068874I2/lt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2806—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Mycology (AREA)
Microbiology (AREA)
Oncology (AREA)
Gastroenterology & Hepatology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Cell Biology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Ultra Sonic Daignosis Equipment (AREA)

LTPA2016031C 2006-08-07 2016-10-27 Dauginės mielomos, naudojant kombinuotas terapijas, pagrįstas anti-CS1 antikūnais, gydymo būdai LTC2068874I2 (lt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US83618506P	2006-08-07	2006-08-07
US94426207P	2007-06-15	2007-06-15
PCT/US2007/075403 WO2008019378A1 (en)	2006-08-07	2007-08-07	Methods of treating multiple myeloma using combination therapies based on anti-cs1 antibodies

Publications (2)

Publication Number	Publication Date
LTPA2016031I1 LTPA2016031I1 (lt)	2016-11-10
LTC2068874I2 true LTC2068874I2 (lt)	2018-11-12

Family

ID=38831279

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
LTEP13168383.1T LT2641601T (lt)	2006-08-07	2007-08-07	Daugybinės mielomos, naudojant kombinuotas terapijas, pagrįstas huluc63 su bortezomibu, gydymo būdai
LTPA2016029C LTPA2016029I1 (lt)	2006-08-07	2016-10-27	Dauginės mielomos, naudojant kombinuotas terapijas, pagrįstas anti-CS1 antikūnais, gydymo būdai
LTPA2016030C LTPA2016030I1 (lt)	2006-08-07	2016-10-27	Dauginės mielomos, naudojant kombinuotas terapijas, pagrįstas anti-CS1 antikūnais, gydymo būdai
LTPA2016031C LTC2068874I2 (lt)	2006-08-07	2016-10-27	Dauginės mielomos, naudojant kombinuotas terapijas, pagrįstas anti-CS1 antikūnais, gydymo būdai

Family Applications Before (3)

Application Number	Title	Priority Date	Filing Date
LTEP13168383.1T LT2641601T (lt)	2006-08-07	2007-08-07	Daugybinės mielomos, naudojant kombinuotas terapijas, pagrįstas huluc63 su bortezomibu, gydymo būdai
LTPA2016029C LTPA2016029I1 (lt)	2006-08-07	2016-10-27	Dauginės mielomos, naudojant kombinuotas terapijas, pagrįstas anti-CS1 antikūnais, gydymo būdai
LTPA2016030C LTPA2016030I1 (lt)	2006-08-07	2016-10-27	Dauginės mielomos, naudojant kombinuotas terapijas, pagrįstas anti-CS1 antikūnais, gydymo būdai

Country Status (23)

Country	Link
US (4)	US8632772B2 (lt)
EP (5)	EP2641601B8 (lt)
JP (1)	JP5340935B2 (lt)
CN (1)	CN101686971B (lt)
AU (1)	AU2007281684C1 (lt)
BR (1)	BRPI0716647A2 (lt)
CA (1)	CA2660356C (lt)
CY (5)	CY1116247T1 (lt)
DK (2)	DK2641601T3 (lt)
ES (2)	ES2535437T3 (lt)
HR (2)	HRP20150449T1 (lt)
HU (4)	HUE029027T2 (lt)
IL (2)	IL196919A (lt)
LT (4)	LT2641601T (lt)
LU (3)	LU93277I2 (lt)
MX (1)	MX2009001441A (lt)
NL (1)	NL300840I2 (lt)
NO (1)	NO346835B1 (lt)
NZ (1)	NZ574978A (lt)
PL (2)	PL2641601T3 (lt)
PT (2)	PT2068874E (lt)
SI (2)	SI2641601T1 (lt)
WO (1)	WO2008019378A1 (lt)

Families Citing this family (26)

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EP2641601B8 (en)	2006-08-07	2016-09-21	AbbVie Biotherapeutics Inc.	Methods of treating multiple myeloma using combination therapies based on HuLuc63 with bortezomib
CA2660102C (en) *	2006-08-07	2017-02-21	Pdl Biopharma, Inc.	Compositions and methods using anti-cs1 antibodies to treat multiple myeloma
WO2009149021A2 (en) *	2008-06-02	2009-12-10	Dana-Farber Cancer Institute, Inc.	Xbp1, cd138, and cs1 peptides
SG191679A1 (en)	2008-06-16	2013-07-31	Immunogen Inc	Novel synergistic effects
JP5675629B2 (ja) *	2008-10-21	2015-02-25	オニキスセラピューティクス，インク．ＯｎｙｘＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ．	ペプチドエポキシケトンを用いた併用療法
AU2010293383B2 (en)	2009-09-10	2014-12-18	Kyowa Kirin Co., Ltd.	Medicament including antibody composition specifically bound to human CC chemokine receptor 4 (CCR4)
WO2011066351A1 (en) *	2009-11-24	2011-06-03	Celgene Corporation	Immunomodulatory compounds for the restoration of vitamin d sensitivity in vitamin d resistant tumor cells
CN102241773B (zh) *	2010-05-13	2014-05-14	四川大学	抗骨髓瘤细胞多克隆抗体及其制备方法
AU2013337247B2 (en)	2012-11-05	2018-08-09	Dana-Farber Cancer Institute, Inc.	XBP1, CD138, and CS1 peptides, pharmaceutical compositions that include the peptides, and methods of using such peptides and compositions
US10494433B2 (en)	2013-11-06	2019-12-03	Bristol-Myers Squibb Company	Combination of anti-KIR and anti-CS1 antibodies to treat multiple myeloma
US20160264670A1 (en)	2013-11-06	2016-09-15	Bristol-Myers Squibb Company	Immunotherapeutic dosing regimens and combinations thereof
PT3071597T (pt) *	2013-11-21	2020-10-08	Hoffmann La Roche	Anticorpos anti-alfa-sinucleína e métodos de utilização
EP3925609B1 (en) *	2014-08-22	2025-07-30	Celgene Corporation	Methods of treating multiple myeloma with immunomodulatory compounds in combination with antibodies
US10752902B2 (en) *	2014-09-23	2020-08-25	Board Of Trustees Of Michigan State University	Compositions comprising fusion proteins useful for modulating an immune response
WO2016054354A1 (en)	2014-10-02	2016-04-07	Dana-Farber Cancer Institute, Inc.	Compositions and methods for treating malignancies
US10011657B2 (en)	2014-10-31	2018-07-03	Abbvie Biotherapeutics Inc.	Anti-CS1 antibodies and antibody drug conjugates
US10302644B2 (en)	2014-11-04	2019-05-28	Dana-Farber Cancer Institute, Inc.	Compositions and methods for treating multiple myeloma
MX2017007097A (es) *	2014-12-04	2017-09-05	Bristol Myers Squibb Co	Combinacion de anticuerpos anti-cs1 y anti-muerte programada 1 (pd1) para tratar cancer (mieloma).
PL3294769T3 (pl)	2015-05-13	2021-07-05	Morphosys Ag	Leczenie szpiczaka mnogiego (mm)
PL3313528T3 (pl)	2015-06-29	2021-12-13	Bristol-Myers Squibb Company	Schematy dawkowania immunoterapeutycznego obejmujące pomalidomid i przeciwciało anty-cs1 w leczeniu raka
CN109498799A (zh) *	2016-03-13	2019-03-22	曹帅	一种用于治疗骨髓增生、骨癌的药物组合物及其用途
US11124579B2 (en)	2017-03-29	2021-09-21	Agency For Science, Technology And Research	Anti oligosaccharide antibody
WO2019104001A1 (en) *	2017-11-22	2019-05-31	Hillstream Biopharma Inc.	Polymeric nanoparticles comprising bortezomib
US10537585B2 (en)	2017-12-18	2020-01-21	Dexcel Pharma Technologies Ltd.	Compositions comprising dexamethasone
US20220390455A1 (en)	2019-11-05	2022-12-08	Bristol-Myers Squibb Company	M-protein assays and uses thereof
CN115368462A (zh) *	2022-07-19	2022-11-22	合肥天港免疫药物有限公司	双特异性抗体及其应用

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Publication number	Priority date	Publication date	Assignee	Title
IL112969A (en)	1994-03-17	2001-05-20	Baxter Int	Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator
DE69633668T2 (de)	1995-05-25	2006-03-09	Shimon Slavin	Allogene zelltherapie für krebs infolge allogener stammzellen transplantation
US7968569B2 (en) *	2002-05-17	2011-06-28	Celgene Corporation	Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
CA2672000C (en) *	2002-05-17	2011-11-29	Celgene Corporation	Methods and compositions using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for treatment and management of lymphoma
US7709610B2 (en) *	2003-05-08	2010-05-04	Facet Biotech Corporation	Therapeutic use of anti-CS1 antibodies
US20050025763A1 (en) *	2003-05-08	2005-02-03	Protein Design Laboratories, Inc.	Therapeutic use of anti-CS1 antibodies
WO2006048877A2 (en) *	2004-11-04	2006-05-11	Fibron Limited	Treatment of b-cell malignancies with fgfr3 inhibitors
EP2641601B8 (en)	2006-08-07	2016-09-21	AbbVie Biotherapeutics Inc.	Methods of treating multiple myeloma using combination therapies based on HuLuc63 with bortezomib
WO2008019379A2 (en)	2006-08-07	2008-02-14	Pdl Biopharma, Inc.	Use of allogeneic effector cells and anti-cs1 antibodies for selective killing of multiple myeloma cells
CA2660102C (en)	2006-08-07	2017-02-21	Pdl Biopharma, Inc.	Compositions and methods using anti-cs1 antibodies to treat multiple myeloma

2007
- 2007-08-07 EP EP13168383.1A patent/EP2641601B8/en active Active
- 2007-08-07 ES ES07840746.7T patent/ES2535437T3/es active Active
- 2007-08-07 SI SI200731803A patent/SI2641601T1/sl unknown
- 2007-08-07 SI SI200731641T patent/SI2068874T1/sl unknown
- 2007-08-07 DK DK13168383.1T patent/DK2641601T3/en active
- 2007-08-07 PL PL13168383T patent/PL2641601T3/pl unknown
- 2007-08-07 NZ NZ574978A patent/NZ574978A/xx unknown
- 2007-08-07 NO NO20090968A patent/NO346835B1/no unknown
- 2007-08-07 DK DK07840746T patent/DK2068874T3/da active
- 2007-08-07 CA CA2660356A patent/CA2660356C/en active Active
- 2007-08-07 PT PT78407467T patent/PT2068874E/pt unknown
- 2007-08-07 AU AU2007281684A patent/AU2007281684C1/en active Active
- 2007-08-07 ES ES13168383.1T patent/ES2589302T3/es active Active
- 2007-08-07 LT LTEP13168383.1T patent/LT2641601T/lt unknown
- 2007-08-07 MX MX2009001441A patent/MX2009001441A/es active IP Right Grant
- 2007-08-07 WO PCT/US2007/075403 patent/WO2008019378A1/en not_active Ceased
- 2007-08-07 EP EP07840746.7A patent/EP2068874B1/en active Active
- 2007-08-07 CN CN200780033988XA patent/CN101686971B/zh active Active
- 2007-08-07 EP EP15152731.4A patent/EP2942057A1/en not_active Withdrawn
- 2007-08-07 PL PL07840746T patent/PL2068874T3/pl unknown
- 2007-08-07 JP JP2009523968A patent/JP5340935B2/ja active Active
- 2007-08-07 EP EP16169025.0A patent/EP3115049A1/en not_active Withdrawn
- 2007-08-07 HU HUE13168383A patent/HUE029027T2/en unknown
- 2007-08-07 HR HRP20150449TT patent/HRP20150449T1/hr unknown
- 2007-08-07 PT PT131683831T patent/PT2641601T/pt unknown
- 2007-08-07 US US11/835,257 patent/US8632772B2/en active Active
- 2007-08-07 BR BRPI0716647A patent/BRPI0716647A2/pt not_active Application Discontinuation
- 2007-08-07 EP EP13168364.1A patent/EP2641600A1/en not_active Withdrawn
2009
- 2009-02-05 IL IL196919A patent/IL196919A/en active Protection Beyond IP Right Term
2013
- 2013-12-23 US US14/139,096 patent/US20140322201A1/en not_active Abandoned
2015
- 2015-04-24 CY CY20151100379T patent/CY1116247T1/el unknown
- 2015-08-24 US US14/834,077 patent/US20160137735A1/en not_active Abandoned
2016
- 2016-02-03 IL IL243933A patent/IL243933A0/en unknown
- 2016-08-18 CY CY20161100817T patent/CY1117992T1/el unknown
- 2016-10-06 HR HRP20161284TT patent/HRP20161284T1/hr unknown
- 2016-10-20 HU HUS1600045C patent/HUS1600045I1/hu unknown
- 2016-10-20 HU HUS1600044C patent/HUS1600044I1/hu unknown
- 2016-10-20 HU HUS1600043C patent/HUS1600043I1/hu unknown
- 2016-10-24 LU LU93277C patent/LU93277I2/fr unknown
- 2016-10-24 LU LU93275C patent/LU93275I2/fr unknown
- 2016-10-24 LU LU93276C patent/LU93276I2/fr unknown
- 2016-10-25 NL NL300840C patent/NL300840I2/nl unknown
- 2016-10-26 CY CY2016037C patent/CY2016037I1/el unknown
- 2016-10-26 CY CY2016038C patent/CY2016038I1/el unknown
- 2016-10-26 CY CY2016036C patent/CY2016036I2/el unknown
- 2016-10-27 LT LTPA2016029C patent/LTPA2016029I1/lt unknown
- 2016-10-27 LT LTPA2016030C patent/LTPA2016030I1/lt unknown
- 2016-10-27 LT LTPA2016031C patent/LTC2068874I2/lt unknown
2017
- 2017-08-07 US US15/670,681 patent/US20170342150A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2008019378A1 (en)	2008-02-14
EP2641600A1 (en)	2013-09-25
PT2641601T (pt)	2016-10-14
SI2641601T1 (sl)	2016-11-30
HRP20161284T1 (hr)	2016-12-16
HUS1600043I1 (hu)	2016-12-28
NO346835B1 (no)	2023-01-23
CY2016037I1 (el)	2017-07-12
US20170342150A1 (en)	2017-11-30
US20160137735A1 (en)	2016-05-19
HRP20150449T1 (xx)	2015-06-05
EP2641601B1 (en)	2016-07-06
LT2641601T (lt)	2016-10-10
JP5340935B2 (ja)	2013-11-13
EP2068874B1 (en)	2015-01-28
EP2942057A1 (en)	2015-11-11
CY1117992T1 (el)	2017-05-17
NZ574978A (en)	2012-08-31
LTPA2016029I1 (lt)	2016-11-10
AU2007281684A1 (en)	2008-02-14
PL2641601T3 (pl)	2017-01-31
NL300840I2 (lt)	2017-01-03
SI2068874T1 (sl)	2015-06-30
LTPA2016031I1 (lt)	2016-11-10
US20140322201A1 (en)	2014-10-30
PL2068874T3 (pl)	2015-06-30
IL243933A0 (en)	2016-04-21
LU93275I2 (fr)	2016-12-27
DK2641601T3 (en)	2016-08-22
ES2535437T3 (es)	2015-05-11
EP2068874A1 (en)	2009-06-17
HUS1600044I1 (hu)	2016-12-28
PT2068874E (pt)	2015-05-21
ES2589302T3 (es)	2016-11-11
CN101686971A (zh)	2010-03-31
NO20090968L (no)	2009-04-30
AU2007281684C1 (en)	2013-12-19
CY2016038I1 (el)	2017-07-12
CN101686971B (zh)	2013-09-11
IL196919A0 (en)	2009-11-18
JP2010500371A (ja)	2010-01-07
US8632772B2 (en)	2014-01-21
US20080152646A1 (en)	2008-06-26
CA2660356C (en)	2016-04-05
BRPI0716647A2 (pt)	2017-05-16
IL196919A (en)	2016-03-31
CY1116247T1 (el)	2017-02-08
HK1129853A1 (en)	2009-12-11
DK2068874T3 (da)	2015-04-27
CY2016036I1 (el)	2017-07-12
HUE029027T2 (en)	2017-01-30
EP2641601B8 (en)	2016-09-21
LTPA2016030I1 (lt)	2016-11-10
HUS1600045I1 (hu)	2016-12-28
LU93276I2 (fr)	2016-12-27
CY2016036I2 (el)	2017-07-12
EP3115049A1 (en)	2017-01-11
CA2660356A1 (en)	2008-02-14
MX2009001441A (es)	2009-07-06
AU2007281684B2 (en)	2013-05-16
EP2641601A1 (en)	2013-09-25
LU93277I2 (fr)	2016-12-27

Publication	Publication Date	Title
LTPA2016030I1 (lt)	2016-11-10	Dauginės mielomos, naudojant kombinuotas terapijas, pagrįstas anti-CS1 antikūnais, gydymo būdai
IL284991A (en)	2021-08-31	Antibodies against cd38 for treatment of multiple myeloma
LTC2076540I2 (lt)	2023-11-10	Nauji anti-cd38 antikūnai, skirti vėžio gydymui
CY2019004I1 (el)	2019-11-27	Τροποποιημενα αντισωματα αντι-ιl-23ρ19
DK2225280T3 (da)	2014-05-26	Bivalente, bispecifikke antistoffer
BRPI0821405A2 (pt)	2015-06-16	Anticorpos biespecíficos, bivalentes
BRPI0821375A2 (pt)	2015-06-16	Anticorpos biespecíficos, bivalentes
DK3401334T3 (da)	2023-03-27	Monoklonale antistoffer mod claudin-18 til cancerbehandling
NO344963B1 (no)	2020-08-03	Humanisert antistoff
BRPI0907532A2 (pt)	2015-07-28	Anticorpos anti-c5ar humanizados
BRPI0807991A2 (pt)	2014-06-17	Anticorpos anti-il-23r elaborados.
DK1948693T3 (da)	2013-06-10	Monoklonale antistoffer mod claudin-18 til behandling af cancer
DK2131860T3 (da)	2014-01-13	Anti-sclerostin-antistoffer
PT2195026E (pt)	2014-03-31	Anticorpos anti-esclerostina
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BRPI0818865A2 (pt)	2015-05-05	Anticorpos monoclonais contra proteína c ativada.
DK1976884T3 (da)	2013-02-25	Anti-ephrinb2-antistoffer og fremgangsmåder til anvendelse deraf.
DK2012814T3 (da)	2013-08-19	Fremgangsmåder til behandling af autoimmunsygdomme
DK2094728T3 (da)	2013-07-01	Fremgangsmåder til anvendelse for human-adapterende monoklonale antistoffer
BRPI0718324A2 (pt)	2013-11-26	Métodos para o tratamento de depressão.
DK1982178T3 (da)	2013-09-08	Fremgangsmåder til behandling af affektbetonede lidelser
BRPI0718609A2 (pt)	2015-06-30	Anticorpos modificadores de doença cancerosa.
DK1866338T3 (da)	2017-01-02	Antistoffer mod cd38 til behandling af myelomatose