LT4010379T - Faktoriaus xa ir jo darinių kompozicijos ir gamybos būdai - Google Patents
Faktoriaus xa ir jo darinių kompozicijos ir gamybos būdaiInfo
- Publication number
- LT4010379T LT4010379T LTEPPCT/US2020/045039T LTUS2020045039T LT4010379T LT 4010379 T LT4010379 T LT 4010379T LT US2020045039 T LTUS2020045039 T LT US2020045039T LT 4010379 T LT4010379 T LT 4010379T
- Authority
- LT
- Lithuania
- Prior art keywords
- derivatives
- compositions
- methods
- preparing factor
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6432—Coagulation factor Xa (3.4.21.6)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962884652P | 2019-08-08 | 2019-08-08 | |
| US202062990885P | 2020-03-17 | 2020-03-17 | |
| PCT/US2020/045039 WO2021026254A2 (en) | 2019-08-08 | 2020-08-05 | Compositions and methods for preparing factor xa and derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT4010379T true LT4010379T (lt) | 2025-07-10 |
Family
ID=74502595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/US2020/045039T LT4010379T (lt) | 2019-08-08 | 2020-08-05 | Faktoriaus xa ir jo darinių kompozicijos ir gamybos būdai |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12398387B2 (lt) |
| EP (2) | EP4010379B1 (lt) |
| JP (2) | JP7668783B2 (lt) |
| CN (1) | CN114258405A (lt) |
| DK (1) | DK4010379T3 (lt) |
| ES (1) | ES3033092T3 (lt) |
| FI (1) | FI4010379T3 (lt) |
| HU (1) | HUE072201T2 (lt) |
| LT (1) | LT4010379T (lt) |
| PL (1) | PL4010379T3 (lt) |
| PT (1) | PT4010379T (lt) |
| SI (1) | SI4010379T1 (lt) |
| WO (1) | WO2021026254A2 (lt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250171515A1 (en) * | 2022-03-03 | 2025-05-29 | The Trustees Of The University Of Pennsylvania | Aav vectors for delivery of glp-1 receptor agonist fusions |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4818700A (en) | 1985-10-25 | 1989-04-04 | Phillips Petroleum Company | Pichia pastoris argininosuccinate lyase gene and uses thereof |
| US4812405A (en) | 1986-02-18 | 1989-03-14 | Phillips Petroleum Company | Double auxotrophic mutants of Pichia pastoris and methods for preparation |
| US4929555A (en) | 1987-10-19 | 1990-05-29 | Phillips Petroleum Company | Pichia transformation |
| US5955349A (en) | 1996-08-26 | 1999-09-21 | Zymogenetics, Inc. | Compositions and methods for producing heterologous polypeptides in Pichia methanolica |
| US5736383A (en) | 1996-08-26 | 1998-04-07 | Zymogenetics, Inc. | Preparation of Pichia methanolica auxotrophic mutants |
| US6258559B1 (en) | 1999-03-22 | 2001-07-10 | Zymogenetics, Inc. | Method for producing proteins in transformed Pichia |
| EP1728798A1 (en) | 2005-06-01 | 2006-12-06 | ZLB Behring GmbH | Coagulation factor X polypeptides with modified activation properties |
| US7939632B2 (en) * | 2006-06-14 | 2011-05-10 | Csl Behring Gmbh | Proteolytically cleavable fusion proteins with high molar specific activity |
| PL3078743T3 (pl) | 2007-09-28 | 2020-11-02 | Portola Pharmaceuticals, Inc. | Antidotum dla inhibitorów czynnika XA i sposoby ich stosowania |
| ES2607935T3 (es) | 2009-03-30 | 2017-04-04 | Portola Pharmaceuticals, Inc. | Antídotos para inhibidores del factor Xa y procedimientos de uso de los mismos |
| US20130230901A1 (en) * | 2012-02-14 | 2013-09-05 | Portola Pharmaceuticals, Inc. | Process for making recombinant antidote to factor xa inhibitor |
| AU2013270682A1 (en) | 2012-06-08 | 2014-12-11 | Biogen Ma Inc. | Procoagulant compounds |
| EP2861614B1 (en) * | 2012-06-14 | 2016-11-30 | Portola Pharmaceuticals, Inc. | METHOD FOR PURIFICATION OF RECOMBINANT FACTOR Xa DERIVATIVES |
| US10364288B2 (en) * | 2013-05-24 | 2019-07-30 | Biogen Ma Inc. | Anti-GPIIB/IIIA antibodies or uses thereof |
| CN103408669B (zh) * | 2013-08-01 | 2016-01-20 | 江苏泰康生物医药有限公司 | Glp-1类似物融合蛋白，及其制备方法和用途 |
| WO2017147522A1 (en) | 2016-02-24 | 2017-08-31 | Portola Pharmaceuticals, Inc. | Lyophilized formulations for factor xa antidote |
| FR3077296A1 (fr) * | 2018-02-01 | 2019-08-02 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Dimeres de variants du facteur x |
-
2020
- 2020-08-05 CN CN202080058518.4A patent/CN114258405A/zh active Pending
- 2020-08-05 EP EP20851033.9A patent/EP4010379B1/en active Active
- 2020-08-05 WO PCT/US2020/045039 patent/WO2021026254A2/en not_active Ceased
- 2020-08-05 PT PT208510339T patent/PT4010379T/pt unknown
- 2020-08-05 EP EP25158352.2A patent/EP4541887A3/en active Pending
- 2020-08-05 LT LTEPPCT/US2020/045039T patent/LT4010379T/lt unknown
- 2020-08-05 SI SI202030630T patent/SI4010379T1/sl unknown
- 2020-08-05 FI FIEP20851033.9T patent/FI4010379T3/fi active
- 2020-08-05 DK DK20851033.9T patent/DK4010379T3/da active
- 2020-08-05 PL PL20851033.9T patent/PL4010379T3/pl unknown
- 2020-08-05 ES ES20851033T patent/ES3033092T3/es active Active
- 2020-08-05 HU HUE20851033A patent/HUE072201T2/hu unknown
- 2020-08-05 US US17/629,999 patent/US12398387B2/en active Active
- 2020-08-05 JP JP2022507622A patent/JP7668783B2/ja active Active
-
2024
- 2024-10-16 JP JP2024181226A patent/JP2024180602A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021026254A2 (en) | 2021-02-11 |
| PT4010379T (pt) | 2025-06-30 |
| ES3033092T3 (en) | 2025-07-30 |
| CN114258405A (zh) | 2022-03-29 |
| EP4010379A4 (en) | 2023-12-20 |
| JP7668783B2 (ja) | 2025-04-25 |
| DK4010379T3 (da) | 2025-06-30 |
| SI4010379T1 (sl) | 2025-08-29 |
| US20220251534A1 (en) | 2022-08-11 |
| HUE072201T2 (hu) | 2025-10-28 |
| JP2022543302A (ja) | 2022-10-11 |
| WO2021026254A3 (en) | 2021-03-18 |
| EP4541887A3 (en) | 2025-08-13 |
| EP4010379A2 (en) | 2022-06-15 |
| US12398387B2 (en) | 2025-08-26 |
| FI4010379T3 (fi) | 2025-06-26 |
| EP4010379B1 (en) | 2025-04-02 |
| EP4541887A2 (en) | 2025-04-23 |
| PL4010379T3 (pl) | 2025-07-28 |
| JP2024180602A (ja) | 2024-12-26 |
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