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LT4084791T - Specifiniai triptaminai, skirti nuotaikos sutrikimams gydyti - Google Patents

Specifiniai triptaminai, skirti nuotaikos sutrikimams gydyti

Info

Publication number
LT4084791T
LT4084791T LTEPPCT/US2021/018534T LTUS2021018534T LT4084791T LT 4084791 T LT4084791 T LT 4084791T LT US2021018534 T LTUS2021018534 T LT US2021018534T LT 4084791 T LT4084791 T LT 4084791T
Authority
LT
Lithuania
Prior art keywords
tryptamines
treatment
specific
mood disorders
mood
Prior art date
Application number
LTEPPCT/US2021/018534T
Other languages
English (en)
Inventor
Andrew Carry KRUEGEL
Jonathan Sporn
Original Assignee
Gilgamesh Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilgamesh Pharmaceuticals, Inc. filed Critical Gilgamesh Pharmaceuticals, Inc.
Publication of LT4084791T publication Critical patent/LT4084791T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LTEPPCT/US2021/018534T 2020-02-18 2021-02-18 Specifiniai triptaminai, skirti nuotaikos sutrikimams gydyti LT4084791T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062978075P 2020-02-18 2020-02-18
PCT/US2021/018534 WO2021168082A1 (en) 2020-02-18 2021-02-18 Specific tryptamines for use in the treatment of mood disorders

Publications (1)

Publication Number Publication Date
LT4084791T true LT4084791T (lt) 2025-02-25

Family

ID=74871827

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/US2021/018534T LT4084791T (lt) 2020-02-18 2021-02-18 Specifiniai triptaminai, skirti nuotaikos sutrikimams gydyti

Country Status (22)

Country Link
US (4) US20220241243A1 (lt)
EP (2) EP4501407A3 (lt)
JP (3) JP7242969B2 (lt)
KR (2) KR20230124103A (lt)
CN (2) CN115135320B (lt)
AU (2) AU2021224899B2 (lt)
BR (1) BR112022016382A2 (lt)
CA (1) CA3172046A1 (lt)
DK (1) DK4084791T3 (lt)
ES (1) ES3014741T3 (lt)
FI (1) FI4084791T3 (lt)
HR (1) HRP20250148T1 (lt)
HU (1) HUE070631T2 (lt)
IL (2) IL301235A (lt)
LT (1) LT4084791T (lt)
MX (2) MX2022010082A (lt)
PL (1) PL4084791T3 (lt)
PT (1) PT4084791T (lt)
RS (1) RS66496B1 (lt)
SI (1) SI4084791T1 (lt)
SM (1) SMT202500143T1 (lt)
WO (1) WO2021168082A1 (lt)

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RS66496B1 (sr) * 2020-02-18 2025-03-31 Gilgamesh Pharmaceuticals Inc Specifični triptamini za upotrebu u lečenju poremećaja raspoloženja
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US20250091993A1 (en) * 2022-01-27 2025-03-20 Terran Biosciences Inc. Salts and solid forms of n-ethyl-2-(5-fluoro-1h-indol-3-yl)-n-methylethan-1-amine
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WO2024046837A1 (en) * 2022-08-31 2024-03-07 Cybin Irl Limited Tryptamine compounds, compositions, and methods of use
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US12129234B1 (en) 2023-08-03 2024-10-29 Gilgamesh Pharmaceuticals, Inc. Crystalline salts of N-ethyl-(5-fluoro-1H-indol-3-yl)-N-methylethan-1-amine
US12157722B1 (en) * 2023-08-03 2024-12-03 Gilgamesh Pharmaceuticals, Inc. Crystalline hydrochloride salts of N-ethyl-2-(5-fluoro-1H-indol-3-yl)-N-methylethan-1-amine
WO2025052388A1 (en) * 2023-09-07 2025-03-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Psychedelic compounds, methods of their preparation and uses thereof
WO2025111597A1 (en) * 2023-11-22 2025-05-30 Gilgamesh Pharmaceuticals, Inc. A treatment for patients with mood disorders using n-ethyl-2-(5-fluoro-1h-indol-3-yl)- n-methylethan-1-amine or a pharmaceutically acceptable salt thereof

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RS66496B1 (sr) * 2020-02-18 2025-03-31 Gilgamesh Pharmaceuticals Inc Specifični triptamini za upotrebu u lečenju poremećaja raspoloženja
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Also Published As

Publication number Publication date
EP4501407A3 (en) 2025-04-23
EP4501407A2 (en) 2025-02-05
MX2022010082A (es) 2022-11-14
US20240317683A1 (en) 2024-09-26
NZ790704A (en) 2024-12-20
CN117503759A (zh) 2024-02-06
AU2021224899A1 (en) 2022-08-25
HUE070631T2 (hu) 2025-06-28
EP4084791B1 (en) 2024-12-18
BR112022016382A2 (pt) 2022-10-25
AU2021224899B2 (en) 2025-02-27
EP4084791A1 (en) 2022-11-09
US20220041551A1 (en) 2022-02-10
WO2021168082A1 (en) 2021-08-26
IL301235A (en) 2023-05-01
JP7640600B2 (ja) 2025-03-05
CN115135320B (zh) 2023-08-29
FI4084791T3 (fi) 2025-03-08
US20240351983A1 (en) 2024-10-24
SI4084791T1 (sl) 2025-04-30
RS66496B1 (sr) 2025-03-31
CA3172046A1 (en) 2021-08-26
HRP20250148T1 (hr) 2025-04-11
PT4084791T (pt) 2025-01-24
ES3014741T3 (en) 2025-04-24
JP2023504308A (ja) 2023-02-02
IL295536B1 (en) 2023-04-01
IL295536A (en) 2022-10-01
SMT202500143T1 (it) 2025-05-12
CN115135320A (zh) 2022-09-30
JP2025071254A (ja) 2025-05-02
DK4084791T3 (da) 2025-02-03
MX2024006123A (es) 2024-06-04
PL4084791T3 (pl) 2025-04-22
JP7242969B2 (ja) 2023-03-20
US11440879B2 (en) 2022-09-13
JP2023063360A (ja) 2023-05-09
IL295536B2 (en) 2023-08-01
KR20220129054A (ko) 2022-09-22
US20220241243A1 (en) 2022-08-04
KR20230124103A (ko) 2023-08-24
KR102567903B1 (ko) 2023-08-18
AU2025201184A1 (en) 2025-03-13

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