LT3268480T - Priemonės ir būdai, skirti panaudoti ląstelių dalijimosi lokusus ląstelių proliferacijos kontroliavimui - Google Patents
Priemonės ir būdai, skirti panaudoti ląstelių dalijimosi lokusus ląstelių proliferacijos kontroliavimuiInfo
- Publication number
- LT3268480T LT3268480T LTEP16760977.5T LT16760977T LT3268480T LT 3268480 T LT3268480 T LT 3268480T LT 16760977 T LT16760977 T LT 16760977T LT 3268480 T LT3268480 T LT 3268480T
- Authority
- LT
- Lithuania
- Prior art keywords
- locks
- measures
- methods
- cell proliferation
- cell division
- Prior art date
Links
- 230000032823 cell division Effects 0.000 title 1
- 230000004663 cell proliferation Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562130270P | 2015-03-09 | 2015-03-09 | |
| US201562130258P | 2015-03-09 | 2015-03-09 | |
| PCT/CA2016/050256 WO2016141480A1 (en) | 2015-03-09 | 2016-03-09 | Tools and methods for using cell division loci to control proliferation of cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3268480T true LT3268480T (lt) | 2021-07-26 |
Family
ID=56879714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP16760977.5T LT3268480T (lt) | 2015-03-09 | 2016-03-09 | Priemonės ir būdai, skirti panaudoti ląstelių dalijimosi lokusus ląstelių proliferacijos kontroliavimui |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20180044686A1 (lt) |
| EP (2) | EP3929298A1 (lt) |
| JP (3) | JP6938380B2 (lt) |
| KR (2) | KR20240013291A (lt) |
| CN (2) | CN107849583B (lt) |
| AU (1) | AU2016228914B2 (lt) |
| CA (1) | CA2978633A1 (lt) |
| DK (1) | DK3268480T3 (lt) |
| HU (1) | HUE055500T2 (lt) |
| IL (1) | IL254385B (lt) |
| LT (1) | LT3268480T (lt) |
| WO (1) | WO2016141480A1 (lt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3478325B1 (en) * | 2016-07-01 | 2024-07-17 | Research Development Foundation | Elimination of proliferating cells from stem cell-derived grafts |
| GB2588249B (en) * | 2017-06-12 | 2023-01-04 | Sinai Health Sys | Allograft tolerance without the need for systemic immune suppression |
| CN108048405A (zh) * | 2018-01-15 | 2018-05-18 | 上海市东方医院 | 稳定表达人内源性INav的细胞模型及其制备方法和用途 |
| WO2020118447A1 (en) * | 2018-12-13 | 2020-06-18 | Sinai Health System | Immunomodulatory cells and uses thereof |
| CN114127560A (zh) * | 2019-03-21 | 2022-03-01 | Uab研究基金会 | 增加细胞对补体介导裂解的敏感性的方法 |
| CN112921052B (zh) * | 2019-12-06 | 2023-07-21 | 中国科学院分子细胞科学卓越创新中心 | 体内细胞增殖标记与示踪系统及其应用 |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| CA3201621A1 (en) | 2020-12-03 | 2022-06-09 | Century Therapeutics, Inc. | Genetically engineered cells and uses thereof |
| US11883432B2 (en) | 2020-12-18 | 2024-01-30 | Century Therapeutics, Inc. | Chimeric antigen receptor system with adaptable receptor specificity |
| WO2025151838A1 (en) * | 2024-01-12 | 2025-07-17 | Sana Biotechnology, Inc. | Safety switches to control in vitro and in vivo proliferation of cell therapy products |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9703633D0 (en) * | 1997-02-21 | 1997-04-09 | Imp Cancer Res Tech | Cancer therapy |
| BRPI0510113B1 (pt) * | 2004-05-21 | 2022-09-27 | President And Fellows Of Harvard College | Compostos de tetraciclinas e análogos das mesmas |
| JP2010528613A (ja) * | 2007-05-29 | 2010-08-26 | クリストファー ビー． リード， | 多能細胞集団を産生する方法およびその使用 |
| EP2300023A2 (en) * | 2008-05-16 | 2011-03-30 | Genelux Corporation | Microorganisms for preventing and treating neoplasms accompanying cellular therapy |
| JP2012525415A (ja) * | 2009-05-01 | 2012-10-22 | オプソテツク・コーポレイシヨン | 眼科疾患を処置または予防するための方法 |
| US20120171213A1 (en) * | 2009-09-10 | 2012-07-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Method of treating tumors |
-
2016
- 2016-03-09 JP JP2017547568A patent/JP6938380B2/ja active Active
- 2016-03-09 CN CN201680026489.7A patent/CN107849583B/zh active Active
- 2016-03-09 HU HUE16760977A patent/HUE055500T2/hu unknown
- 2016-03-09 KR KR1020247002264A patent/KR20240013291A/ko active Pending
- 2016-03-09 EP EP21174106.1A patent/EP3929298A1/en active Pending
- 2016-03-09 WO PCT/CA2016/050256 patent/WO2016141480A1/en not_active Ceased
- 2016-03-09 CN CN202111608016.7A patent/CN115323000B/zh active Active
- 2016-03-09 CA CA2978633A patent/CA2978633A1/en active Pending
- 2016-03-09 US US15/556,146 patent/US20180044686A1/en active Pending
- 2016-03-09 AU AU2016228914A patent/AU2016228914B2/en active Active
- 2016-03-09 KR KR1020177028536A patent/KR102628872B1/ko active Active
- 2016-03-09 LT LTEP16760977.5T patent/LT3268480T/lt unknown
- 2016-03-09 DK DK16760977.5T patent/DK3268480T3/da active
- 2016-03-09 EP EP16760977.5A patent/EP3268480B1/en active Active
-
2017
- 2017-09-07 IL IL254385A patent/IL254385B/en active IP Right Grant
-
2021
- 2021-06-23 JP JP2021103910A patent/JP7284213B2/ja active Active
-
2022
- 2022-05-26 US US17/825,784 patent/US20220325289A1/en active Pending
-
2023
- 2023-05-18 JP JP2023081942A patent/JP2023103412A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3929298A1 (en) | 2021-12-29 |
| HUE055500T2 (hu) | 2021-11-29 |
| AU2016228914A1 (en) | 2017-09-21 |
| KR20170136528A (ko) | 2017-12-11 |
| JP7284213B2 (ja) | 2023-05-30 |
| IL254385B (en) | 2021-04-29 |
| JP6938380B2 (ja) | 2021-09-22 |
| JP2018507701A (ja) | 2018-03-22 |
| JP2021166529A (ja) | 2021-10-21 |
| CN115323000A (zh) | 2022-11-11 |
| WO2016141480A1 (en) | 2016-09-15 |
| JP2023103412A (ja) | 2023-07-26 |
| CN107849583A (zh) | 2018-03-27 |
| KR20240013291A (ko) | 2024-01-30 |
| CN107849583B (zh) | 2022-01-14 |
| AU2016228914B2 (en) | 2022-04-21 |
| US20220325289A1 (en) | 2022-10-13 |
| CN115323000B (zh) | 2025-03-14 |
| KR102628872B1 (ko) | 2024-01-26 |
| CA2978633A1 (en) | 2016-09-15 |
| EP3268480A1 (en) | 2018-01-17 |
| EP3268480B1 (en) | 2021-05-19 |
| IL254385A0 (en) | 2017-11-30 |
| US20180044686A1 (en) | 2018-02-15 |
| EP3268480A4 (en) | 2018-07-04 |
| DK3268480T3 (da) | 2021-07-26 |
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