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KR900701278A - 바이러스 감염 치료용 담즙산 - Google Patents

바이러스 감염 치료용 담즙산

Info

Publication number
KR900701278A
KR900701278A KR1019900701043A KR900701043A KR900701278A KR 900701278 A KR900701278 A KR 900701278A KR 1019900701043 A KR1019900701043 A KR 1019900701043A KR 900701043 A KR900701043 A KR 900701043A KR 900701278 A KR900701278 A KR 900701278A
Authority
KR
South Korea
Prior art keywords
compound
disease
formula
treatment
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019900701043A
Other languages
English (en)
Inventor
크리스토퍼 제임스 샤프
Original Assignee
시. 비. 크래이그
피존스 피엘시
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888822012A external-priority patent/GB8822012D0/en
Priority claimed from GB888822015A external-priority patent/GB8822015D0/en
Priority claimed from GB888822020A external-priority patent/GB8822020D0/en
Application filed by 시. 비. 크래이그, 피존스 피엘시 filed Critical 시. 비. 크래이그
Publication of KR900701278A publication Critical patent/KR900701278A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음

Description

바이러스 감염 치료용 담즙산
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (9)

  1. 제약용으로 사용되는 하기 구조식(Ⅰ)의 화합물 및 제약상 허용되는 그의 염.
    식중, R1과 R2는 둘다(H, α-OH)이거나 또는 둘다 0을 나타내고, R3는 (H,H) 또는 O를 나타내며, R4는 OH또는 NH(CH2)2SO3H를 나타내되, 단 (i)R1과 R2가 둘다 (H, α-OH)이고, R3가 (H,H)인 경우에는, R4는 NH(CH2)2SO3H이고, (ii)R1과 R2가 둘다 O이고, R3가 O인 경우에는, R4는 NH(CH2)2SO3H 나타낸다.
  2. 엔벨롭트(enveloped)바이러스에 의해 유발되는 질병 치료용 의약의 제조에 있어서, 유효 성분으로서 사용되는 제1항의 구조식(I) (식 중의 부호의 정의는 제1항과 동일하되, (ii)의 조건은 제외됨)외 화합물.
  3. 제2항에 있어서, 질병이 AIDS인 화합물.
  4. 제2항에 있어서, 질병이 인플루엔자 또는 파라인플루엔자인 화합물.
  5. 제2항에 있어서, 질병이 헤르페스인 화합물.
  6. 제2항 내지 제5항 중 어느 하나의 항에 있어서, 구조식(I)의 화합물이 데히드로콜린산인 화합물
  7. 제2항 내지 제5항 중 어느 하나의 항에 있어서, 구조식(I)의 화합물이 타우로케노데옥시콜린산인 화합물.
  8. 제약상 허용가능한 보조제, 희석제 또는 담체와 함께, 제1항의 화합물 중 1종 이상을 유효 성분으로서 함유하는 제약 조성물.
  9. 엔벨롭트 바이러스에 의해 유발된 질병을 앓는 환자 또는 이러한 질병에 접촉 위험이 있는 환자에게 제2항의 구조식(I)의 화합물을 치료 유효량으로 투여하는 것으로 이루어진 상기 질병의 치료볍 또는 예방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900701043A 1988-09-20 1989-09-14 바이러스 감염 치료용 담즙산 Withdrawn KR900701278A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB8822015.7 1988-09-20
GB8822012.4 1988-09-20
GB888822012A GB8822012D0 (en) 1988-09-20 1988-09-20 Method of treatment
GB8822020.7 1988-09-20
GB888822015A GB8822015D0 (en) 1988-09-20 1988-09-20 Method of treatment
GB888822020A GB8822020D0 (en) 1988-09-20 1988-09-20 Method of treatment
PCT/GB1989/001080 WO1990003172A2 (en) 1988-09-20 1989-09-14 Bile acids for treatment of viral infections

Publications (1)

Publication Number Publication Date
KR900701278A true KR900701278A (ko) 1990-12-01

Family

ID=27264092

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900701043A Withdrawn KR900701278A (ko) 1988-09-20 1989-09-14 바이러스 감염 치료용 담즙산

Country Status (6)

Country Link
EP (2) EP0365139A3 (ko)
JP (1) JPH04500670A (ko)
KR (1) KR900701278A (ko)
AU (1) AU4328189A (ko)
PT (1) PT91745B (ko)
WO (1) WO1990003172A2 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1255450B (it) * 1992-06-30 1995-10-31 Montefarmaco Spa Uso di acidi biliari come agenti antivirali
CA2156717C (en) * 1993-02-23 2001-05-29 Daniel E. Kahne Solution and solid-phase formation of glycosidic linkages
US5639866A (en) * 1993-02-23 1997-06-17 Princeton University Single-step formation of multiple glycosidic linkages
DE4316347C1 (de) * 1993-02-26 1994-08-18 Ina Dr Levi Verfahren zur Herstellung einer pharmazeutischen Zubereitung und Verwendung derselben zur Behandlung bestimmter Erkrankungen
CA2167537A1 (en) * 1993-07-19 1995-02-02 Tsuneo Ozeki Hepatitis c virus proliferation inhibitor
US9136083B2 (en) 2013-03-15 2015-09-15 Regal Beloit America, Inc. Enclosed bus bar fuse holder
JP2025014084A (ja) * 2021-12-07 2025-01-29 慶應義塾 ウイルス増殖抑制剤
CN115414370A (zh) * 2022-10-14 2022-12-02 华中农业大学 牛磺胆酸钠在制备治疗或预防流感病毒感染的药物中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591687A (en) * 1968-03-13 1971-07-06 George A Bray Bile acids and derivatives thereof as anorectic agents
BE792826A (fr) * 1971-12-16 1973-03-30 Intellectual Property Dev Corp Composition et procede pour abaisser les taux de cholesterol etde lipides chez les mammiferes
IT1101649B (it) * 1978-12-15 1985-10-07 Lehner Ag Composizione farmaceutica ad azione prolungata contenente acidi biliari
AU2272883A (en) * 1982-12-22 1984-06-28 Herpes Pharmaceutical Inc. Pharmaceutical compositions of steriods for treatment of herpes simplex infections
GB8417895D0 (en) * 1984-07-13 1984-08-15 Marples B A Pharmaceutical anti-fungal composition
GB8706313D0 (en) * 1987-03-17 1987-04-23 Health Lab Service Board Treatment & prevention of viral infections
JPH06302932A (ja) * 1993-04-09 1994-10-28 Toyo Electric Mfg Co Ltd プリント配線基板

Also Published As

Publication number Publication date
EP0435926A1 (en) 1991-07-10
AU4328189A (en) 1990-04-18
EP0365139A3 (en) 1990-08-01
PT91745B (pt) 1995-05-31
WO1990003172A3 (en) 1990-06-28
EP0365139A2 (en) 1990-04-25
PT91745A (pt) 1990-03-30
WO1990003172A2 (en) 1990-04-05
JPH04500670A (ja) 1992-02-06

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19900519

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid