KR20180127780A - Chinese medicine for treating hyperostosis - Google Patents

Abstract

The present invention discloses a Chinese medicine for treating bone hyperplasia, which is obtained with 20-30 parts by weight of sheep bones, 10-20 parts by weight of Rehmannia glutinosa, 10-20 parts by weight of Eucommia ulmoides, 5-10 parts by weight of Carthamus tinctorius, 5-10 parts by weight of Spatholobus suberectus, 4-8 parts by weight of Ledebouriella seseloides and 3-9 parts by weight of Eupolyphaga sinensis. The Chinese medicament of the present invention for treating the bone hyperplasia has an inhibitory effect on the treatment of primary and secondary bone hyperplasia.

Description

{CHINESE MEDICINE FOR TREATING HYPEROSTOSIS}

The present invention relates to a Chinese medicine for the treatment of hyperostosis.

Bone hypertrophy, also known as proliferative bone arthritis, osteoarthritis (OA), degenerative arthrosis, senile arthritis, and hypertrophiarthritis, is a common complication of joint overload, Arthralgia, limitation of motion, and the like. By degeneration and retrogression of cartilage, intervertebral disc, ligament, and other soft tissues, thickening of the bony spur and synovium occurs at the joint edge, destroying the bones and subsequently causing bone hyperplasia and dysarthrasis. There are two types of bone hyperplasia: primary bone hyperplasia and secondary bone hyperplasia. There is no effective cure, and the only way is to supplement a large amount of calcium.

Symptoms and symptoms:

1. Cervical vertebral hyperosteogeny:

Clinical symptoms include: neck stiffness, limitation of movement, click in case of neck movement, pain radiating to shoulder and upper limb, numbness, And electric shock-like feeling in the hands and fingers may be exacerbated by neck movements, other lesions associated with other parts appearing as other symptoms, paralysis in the final stages; Severe hypertrophic cervical vertebrae further have cervical spondylosis hypertension, cardiovascular and cerebrovascular disease, gastritis, angina, dysphagia, and the like.

2. Lumbar vertebral hyperosteogeny:

The primary site is most commonly the 3rd and 4th lumbar spine; Clinical symptoms include aching pain, swelling pain, stiffness and fatigue of the lumbar and waist soft tissues, and even bend limitation; If adjacent nerve roots are squeezed, they will cause corresponding symptoms such as local pain, stiffness, dorsal root neuralgia, jerkiness, etc.; If the sciatic nerve is depressed, the lower limb is removed from the sciatic neuritis, the occurrence of severe stiffness and pain, causalgia, throbbing pain and affected limb, Gt; wandering < / RTI >

3. Knee-joint hyperosteogeny:

In the early stages, patients with slow onset do not have severe knee pain, but continue to have dull pain; Depending on climate change, the temperature gets worse when the temperature drops; The patient has knee joint pain and stiffness, but after a few moves he gets better, at the start of morning movements, after a long walk, in intense exercise, or if he starts to sit and walk for a long time; Patients are difficult to climb or descend a stairway, knee joints weaken and fall easily when going down stairs; When it occurs in squatting, there are knee joint pain and stiffness, in severe cases, soring and edema pain, and limping; In patients with rheumatism, the knee joints are reddish, swollen, abnormal, and functionally restricted; There are clicks when stretching or bending the knee joint; Some patients have joint thydrops and have obvious edema and compression at the local area of the joint.

Bones of sheep include calcium phosphate, calcium carbonate and collagen. This has the effect of warming the liver and improving the characteristics and flavor, kidney and muscle. These include thrombocytopenia eclampsia, aplastic anemia, arthralgia and myalgia, waist weakening, gonorrhea, stranguria, chronic diarrhea, diarrhea, lingering dysentery, and the like. In a book called Yin Shi Zheng Yao, a pair of sheep bone, 6 grams of dried tangerine peel, 6 grams of galangal, 6 grams of Amomum tsaoko, 30 grams of fresh ginger, It has been reported that some salt and sheep bone porridge prepared by cooking with water have good effects in treating consumption and waist weakness.

Therefore, it is necessary to develop Chinese medicines having positive bones as a major substance component for treating bone hypertrophy.

It is an object of the present invention to provide a Chinese medicine having good bodily bone as a main ingredient which is produced by combining good pharmacological properties and development effects and the effects of traditional pharmaceutical substances and research results of modern pharmacology.

Meanwhile, the present invention provides a Chinese medicine for treating bone hyperplasia, which comprises 20 to 30 parts by weight of bone, Rhizome of rehmannia 10-20, Eucommia ulmoides 10-20, Carthamus Tinctorius 5-10, Caulis Spatholobi 5-10, Radix Saposhnikoviae 4-8, and Eupolyphaga seu Steleophaga 3-9.

The method of manufacturing the Chinese medicine comprises the following steps:

Material preparing step: Weighing parts: 20-30 for sheep bone, 10-20 for dioscorea opposite, 10-20 for mite, 5-10 for safflower, 5-10 for blood, Preparing preparations 3-9;

Crushing step: uniformly mixing the components and pulverizing into powders;

Decocting step: The powders are placed in boiling water 10-20 times the weight of the powder, boiled for 3-5 minutes, and then reduced to obtain the Chinese medicine of the present invention for treating bone hyperplasia. Lt; / RTI > for 30-50 minutes.

Methods of application of the Chinese medicaments of the present invention include:

External application: The Chinese medicine is uniformly applied to the affected area three times a day for 5 days of treatment;

Oral administration: Take 50 ml of the above Chinese medicine, mix in 40 ml of warm boiled water, and mix uniformly.

The medical properties of the ingredient materials used in the preparation are as follows:

Sheep bone: The positive bone contains calcium phosphate, calcium carbonate and collagen; Has the characteristics and flavor of warming the liver, and has the effect of improving kidney and muscle; Low platelet hypertrophy, poorly regenerating anemia, arthralgia and myalgia, weakness in the back, gonorrhea, pain urination, chronic diarrhea, persistent dysentery, and the like. The chemical composition of the bone varies depending on the site and age. Among the ingredients, the most obvious difference is moisture and lipid. The bone contains a large amount of inorganic substances therein, and calcium phosphate accounts for more than half of the bone. It also includes small amounts of calcium carbonate, magnesium phosphate and trace amounts of fluorine, chlorine, sodium, potassium, iron, aluminum and the like. Despite the low fluoride content, it is an important component of the bone. The organic substances contained in the bone are collagen, osseomucoid, and elasticin-like substances; There are also triglycerides (high in content), phospholipids and low amounts of glycogen.

The Chinese medicine of the present invention for treating bone hypertrophy has an inhibitory effect on the treatment of primary and secondary bone hyperplasia, and the present invention also has an additional technical effect of alleviating pain and enhancing joint motion ability. The Chinese medicine of the present invention is applied for external use and can also be taken orally; In addition, topical application may be combined with oral administration to achieve a better therapeutic effect.

Other features and advantages of the invention will be described in detail from the following embodiments.

Without losing the generality, the present invention provides a Chinese medicine for treating bone hyperplasia, wherein the substance components are in parts by weight: positive bone 20-30, yam 10-20, mosquito 10-20, safflower 5-10, 5-10, 4-8, and 3-9.

The method of manufacturing the Chinese medicine comprises the following steps:

Preparation stage of material: Prepare for 20-30 weight loss, 10-20 yam, 10-20 mushroom, 10-20 mushroom, 5-10 mushroom, 5-10 mushroom, 4-8 mushroom, 3-9 mushroom.

Grinding step: uniformly mixing the components and pulverizing into powder;

Draining step: The powders are placed in boiling water 10-20 times the weight of the powder, boiled for 3-5 minutes and then cooled at a reduced temperature to obtain a Chinese medicine of the present invention for treating bone hypertrophy Steps that hang for 30-50 minutes.

Methods of application of the Chinese medicaments of the present invention include:

Externally applied: The Chinese medicine is uniformly applied to the affected area 3 times a day for 5 days of treatment;

Oral administration: Take 50 ml of the above-mentioned Chinese medicine, mix in 40 ml of warm boiled water, and mix uniformly.

The Chinese medicine of the present invention for treating bone hypertrophy has an inhibitory effect on the treatment of primary and secondary bone hyperplasia, and the present invention also has an additional technical effect of alleviating pain and enhancing joint motion ability. The Chinese medicine of the present invention is applied for external use and can also be taken orally; In addition, topical application may be combined with oral administration to achieve a better therapeutic effect.

The present invention is described in more detail by the following examples.

Example 1

Treatment of mild primary hyperostosis:

The Chinese medicine of the present invention for treating bone hypertrophy takes 20 g of sheep bone, 10 g of yam, 10 g of mugwort, 5 g of safflower, 5 g of blood, 5 g of windshield, Uniformly mixing the components, pulverizing them into powder; The powders are obtained by adding 10-20 times the weight of the powder to boiling water, boiling for 3-5 minutes, and also reducing for 30-50 minutes at reduced temperature.

Wherein said Chinese medicament is applied uniformly to said bifurcation site during a three-day, five-day course of treatment; Pain was markedly relieved after three treatment courses; Pain was removed after 8 treatment courses; It was also treated after 15 consecutive treatment sessions.

Example 2:

Treatment of moderate primary hyperostosis:

Chinese medicine of the present invention for treating bone hypertrophy takes 22 g of sheep bone, 10 g of yam, 13 g of mugwort, 6 g of safflower, 6 g of blood, 6 g of windbreak, Uniformly mixing the components, pulverizing them into powder; The powders are obtained by adding 10-20 times the weight of the powder to boiling water, boiling for 3-5 minutes, and also reducing for 30-50 minutes at reduced temperature.

Preferably, in one preferred technical solution of this embodiment, the material components also comprise 4 g of Rhizoma Curcumae and 5 g of Ostrea gigas.

Wherein said Chinese medicament is applied uniformly to said bifurcation site during a treatment period of 3 times a day for 5 days; Pain was markedly relieved after 4 treatment courses; Pain was removed after 10 treatment courses; It was also treated after continuous application for 20 treatment courses.

Example 3:

Treatment of severe primary hyperostosis:

Chinese medicine of the present invention for treating bone hypertrophy takes 25 grams of sheep bone, 15 grams of yam, 15 grams of bamboo shoots, 7 grams of safflower, 8 grams of bloodshed, 6 grams of windshield, Uniformly mixing the components, pulverizing them into powder; The powders are obtained by adding 10-20 times the weight of the powder to boiling water, boiling for 3-5 minutes, and also reducing for 30-50 minutes at reduced temperature.

Preferably, in one preferred technical solution of this embodiment, the material components also contain 5 g of turmeric and 8 g of boric acid.

Wherein said Chinese medicine is uniformly applied to said affected area three times a day; 50 ml of the above-mentioned Chinese medicines are mixed in warm boiled water, and are uniformly mixed and then taken for 4 times a day for 5 days during the course of treatment; Pain was markedly relieved after 4 treatment courses; Pain was removed after 10 treatment courses; It was also treated after continuous application for 20 treatment courses.

Example 4

Treatment of Severe Secondary Hyperostosis:

The Chinese medicine of the present invention for treating bone hypertrophy takes 28 g of sheep bone, 16 g of yam, 18 g of mosquito, 9 g of safflower, 8 g of blood, 8 g of wind, Uniformly mixing the components, pulverizing them into powder; The powders are obtained by adding 10-20 times the weight of the powder to boiling water, boiling for 3-5 minutes, and also reducing for 30-50 minutes at reduced temperature.

Preferably, in one preferred technical solution of this embodiment, the material components also comprise 6 g of turmeric and 12 g of corn.

Wherein said Chinese medicine is uniformly applied to said affected area three times a day; 50 ml of the above-mentioned Chinese medicines are mixed in warm boiled water, and are uniformly mixed and then taken for 4 times a day for 5 days during the course of treatment; Pain was markedly relieved after 4 treatment courses; Pain was removed after 10 treatment courses; It was also treated after continuous application for 20 treatment courses.

Example 5

Treatment of mild or moderate secondary hyperostosis:

The Chinese medicine of the present invention for treating bone hypertrophy takes 30 grams of sheep bone, 20 grams of yam, 20 grams of bamboo shoots, 10 grams of safflower, 10 grams of bloodshed, 8 grams of windshield, Uniformly mixing the components, pulverizing them into powder; The powders are obtained by adding 10-20 times the weight of the powder to boiling water, boiling for 3-5 minutes, and also reducing for 30-50 minutes at reduced temperature.

Wherein said Chinese medicament is applied uniformly to said bifurcation site during a three-day, five-day course of treatment; Pain was markedly relieved after 4 treatment courses; Pain was removed after 8 treatment courses; It was also treated after 15 consecutive treatment sessions.

From these test examples it can be seen that the Chinese pharmaceutical compounds of the present invention may have a special effect in bone hyperplasia. According to statistics, nearly 200 patients with some form of bone hypertrophy can be effectively treated after applying the Chinese medicine of the present invention. In addition, it did not cause skin irritation after application and had almost no side effects after oral administration.

Claims (5)

Chinese medicines for the treatment of hyperostosis, by weight: sheep bone 20-30, Rhizome of rehmannia 10-20, Eucommia ulmoides 10-20, Carthamus tinctorius ) 5-10, Caulis Spatholobi 5-10, Radix Saposhnikoviae 4-8, and Eupolyphaga seu Steleophaga 3-9. The Chinese medicine according to claim 1, wherein it is produced by weight: positive bone 22, lipid 10, mite 13, safflower 6, blood red 6, windblower 4, The Chinese medicine according to claim 1, which is manufactured by weight: positive bones 25, 15, 15, safflower 7, blood 8, wind 6, The Chinese medicine according to claim 1, which is manufactured by weight: positive bone 28, lipid 16, mosquito 18, safflower 9, blood redness 8, windshield 8, The Chinese medicine according to any one of claims 1 to 4, wherein the substance components further comprise Rhizoma Curcumae 4-6 and Ostrea gigas 5-12.