KR20180105998A - A cosmetic composition having excellent skin exfoliation and wrinkle improvement - Google Patents

Abstract

The present invention relates to a cosmetic composition having excellent skin exfoliation and wrinkle-improving effects. In one embodiment, the cosmetic composition is selected from the group consisting of gluconolactone, lactobionic acid, glycolic acid, lactic acid, citric acid, mandelic acid, ) And hydroxyphenylpropamidobenzoic acid as an active ingredient.

Description

TECHNICAL FIELD The present invention relates to a cosmetic composition which is superior in skin exfoliation and wrinkle improving effect,

The present invention relates to a cosmetic composition having excellent skin exfoliation and wrinkle-improving effects.

The most important role of the skin is to prevent heat and water loss from the inside while acting as a defense barrier to protect the skin from external bacterial invasion and damage.

The skin consists of several layers, the outermost part of which is called the epidermis, and below it are the dermis and the subcutaneous fat layer. The epidermis is further subdivided into the horny layer, the granular layer, the superficial layer, and the basal layer, and the epidermal cells formed in the basal layer take up to 14 days to reach the granular layer, and the keratohyalin initiates the keratinization in the granular layer.

The body fluids in the cells have already exited, and the cells have flattened and become keratinized. The nucleus, cytoplasm and organelles of the cell are degenerated, replaced with keratohelinin and changed back to elidin (Eleidin) And the lifetime of the cells is terminated and they are pushed up to the stratum corneum. The stratum corneum is composed of differentiated epidermal cells (keratinocytes) and interstitial lipids (Skin Lipids). It protects the body from external substances and protects the body from external physical, chemical and biological stimuli . The keratinocytes are connected by a protein called desmosomes, and the desmosomes are degraded as they go up to the upper part of the stratum corneum to weaken the cohesion between the keratinocytes. Finally, the keratinocytes are separated from the skin and fall off. In normal skin, the stratum corneum is composed of 15-20 layers and it takes 15-20 days to completely separate them.

However, as the skin ages, the thickness of skin, dermis, and subcutaneous tissues becomes thinner, the skin's moisture content sharply decreases, and changes in the ECM (Extracellular Matrix) component, which gives skin elasticity, Wrinkles, and the separation of the stratum corneum becomes later than normal, so that the stratum corneum becomes thicker (stratum corneum) and the skin loses its vitality. Keratinic stratification is mainly caused by decrease of moisture of skin, formation and activity of desmosomal degradation enzyme, and deterioration of cell activity, and causes aging of skin, exposure to ultraviolet rays, and pollution. By intentionally thinning the thickened stratum corneum by the internal / external factors, the activity or regeneration of the living cells under the stratum corneum is increased to soften the skin, and the effect such as wrinkle removal, suppression of acne occurrence, There have been a lot of studies to solve the stratum corneum stratification within a range that does not exist.

In order to resolve keratin layering, the skin is rubbed physically or chemically depilated. Particularly, chemical peeling has additional effects such as improvement of fine wrinkles, rough skin relaxation, and removal of dirt. The substances used for chemical peeling are primarily AHA (Alpha-Hydroxy Acid) and BHA (Beta-Hydroxy Acid).

Among them, alpha hydroxy acid (AHA) is a compound in which an alcohol group or a hydroxy group is added to a carbon at a position of a carboxylic acid (Carboxylic Acid), and the ion binding energy To remove the keratin and promote the formation of new cells to shorten the period of keratinization process as the skin ages, thereby improving the skin by promoting the activity of the skin cells. In addition, it promotes the production of collagen and elastin by fibroblast to promote skin elasticity and softness, and promotes the production of mucopolysaccharide, an important extracellular matrix component of the dermis, Promotes moisturizing. Development of a cosmetic composition for removing skin horny with alpha-hydroxy acid as an active ingredient has been actively developed. However, the above-mentioned alpha hydroxy acid has a large stimulus to the skin, and thus has a problem to be used for exfoliating purposes.

The background art relating to the present invention is disclosed in Korean Patent Laid-Open Publication No. 2011-0051392.

It is an object of the present invention to provide a cosmetic composition which is superior in skin exfoliation and skin texture improving effect when applied to skin.

Another object of the present invention is to provide a cosmetic composition which is superior in skin elasticity, skin tone and skin moisturizing effect when applied to skin.

Another object of the present invention is to prevent skin irritation and provide a cosmetic composition harmless to human body.

One aspect of the present invention relates to a cosmetic composition excellent in skin exfoliation and wrinkle-reducing effect. In one embodiment, the cosmetic composition comprises from 0.1 to 15% by weight of gluconolactone, from 0.1 to 15% by weight of lactobionic acid, from 0.1 to 15% by weight of glycolic acid, 0.1 to 15% by weight of citric acid, 0.1 to 15% by weight of mandelic acid and 0.01 to 5% by weight of hydroxyphenyl propamidobenzoic acid, As an active ingredient.

In one embodiment, the gluconolactone and lactobionic acid, glycolic acid, lactic acid, citric acid, and mandelic acid may be included in a weight ratio of 1: 3 to 1:10.

In one embodiment, the gluconolactone, lactobionic acid, glycolic acid, lactic acid, citric acid, and mandelic acid may be included in an amount of 16 wt% to 55 wt% based on the total weight of the cosmetic composition.

In one embodiment, the cosmetic composition may further comprise 0.1 to 15% by weight of tartaric acid based on the total weight of the cosmetic composition.

In one embodiment, the cosmetic composition may be a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation or spray formulation .

In one embodiment, the cosmetic composition may be an oil-in-water (O / W), a water in oil (W / O), a water in silicone (O / W / O) or Water-in-Oil-in-Water (W / O / W) formulation.

The cosmetic composition according to the present invention is harmless to the human body. It has excellent skin exfoliation and skin texture improving effect when applied to the skin, has excellent skin elasticity improvement effect such as improvement in wrinkles in the eyes, have.

1 (b) is a photograph of skin horny skin immediately after use of the cosmetic composition, and FIG. 1 (c) is a photograph of the horny skin of the skin after 2 weeks of using the cosmetic composition 1 (d) is a photograph of skin horny skin after 4 weeks of using the cosmetic composition.
FIG. 2 (b) is a photograph of the skin immediately after use of the cosmetic composition, and FIG. 2 (c) is a photograph of the skin after 2 weeks of using the cosmetic composition And Fig. 2 (d) is a photograph of the skin after 4 weeks of using the cosmetic composition.
FIG. 3 (a) is a photograph of eye wrinkles before use of the cosmetic composition according to the present invention, FIG. 3 (b) is a photograph of eye wrinkles after 2 weeks of using the cosmetic composition, After 4 weeks of use, it is a wrinkled eye.
4 (b) is a photograph of the dermal density of the skin after 2 weeks of using the cosmetic composition, and FIG. 4 (c) is a photograph of the dermal density of the skin after 2 weeks of using the cosmetic composition, Is a photograph of skin dermal density after 4 weeks of using the cosmetic composition.
FIG. 5 is a graph comparing the degree of skin irritation with the examples according to the present invention and the comparative cosmetic composition according to the present invention, the dermal density improvement, the skin texture improvement, the exfoliation effect, and the period of use until the above- It is a graph.

In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear.

It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory and are intended to be exemplary, self-explanatory, allowing for equivalent explanations of the present invention.

Superior skin exfoliation and wrinkle improvement Cosmetics  Composition

One aspect of the present invention relates to a cosmetic composition excellent in skin exfoliation and wrinkle-reducing effect. In one embodiment, the cosmetic composition comprises from 0.1 to 15% by weight of gluconolactone, from 0.1 to 15% by weight of lactobionic acid, from 0.1 to 15% by weight of glycolic acid, 0.1 to 15% by weight of citric acid, 0.1 to 15% by weight of mandelic acid and 0.01 to 5% by weight of hydroxyphenyl propamidobenzoic acid, As an active ingredient.

The gluconolactone and lactobionic acid are polyhydroxy acid (PHA) having a relatively large molecular weight, less skin irritation and can be stored in the skin for a long time, and are excellent in skin tone and wrinkle removing effect.

The gluconolactone is effective for photoaging and sensitive skin, and has an excellent conditioning effect such as a skin barrier function by enhancing moisture retention, and is effective for skin exfoliation, skin wrinkle improvement, skin firming, and pore management.

In one embodiment, the gluconolactone is contained in an amount of 0.1 to 15% by weight based on the total weight of the cosmetic composition. In this range, the effect of controlling the pH of the skin without skin irritation can be excellent. When the gluconolactone is contained in an amount of less than 0.1% by weight, the skin texture and the exfoliation effect are insignificant. When the gluconolactone is contained in an amount exceeding 15% by weight, stability of the cosmetic formulation decreases, skin irritation increases, . For example, 2 to 10% by weight.

The lactobionic acid is a polyhydroxy acid (PHA) derived from Milk Sugar. It is a potent antioxidant that has a strong ability to bind and attract water molecules and is excellent in water supply ability. The lactobionic acid has excellent exfoliation effect, mitigates or reduces skin wrinkles and wrinkles, improves skin elasticity, reduces skin aging phenomenon, destroys enzyme (MMP ) To protect the skin from damage by sunlight.

In one embodiment, the lactobionic acid is contained in an amount of 0.1 to 15% by weight based on the total weight of the cosmetic composition. In this range, the effect of controlling the pH of the skin without skin irritation can be excellent. When the lactobionic acid is contained in an amount of less than 0.1% by weight, the effect of improving skin texture and exfoliation is insignificant. When the amount of the lactobionic acid is more than 15% by weight, the skin tone improvement effect and formulation stability of the cosmetic composition are decreased, However, the production cost is increased and the economical efficiency is lowered. For example, 0.1 to 2% by weight. In one embodiment, the gluconolactone may be included in an amount higher than the lactobionic acid.

The glycolic acid is contained in an amount of 0.1 to 15% by weight based on the total weight of the cosmetic composition. When the content of glycolic acid is less than 0.1% by weight, the effect of removing skin horny is insignificant. When the content of glycolic acid is more than 15% by weight, stability of cosmetic formulation decreases, skin irritation increases, do. For example, 2 to 10% by weight.

The lactic acid is contained in an amount of 0.1 to 15% by weight based on the total weight of the cosmetic composition. When the lactic acid is contained in an amount of less than 0.1% by weight, the skin exfoliating effect is insignificant, and when it is more than 15% by weight, stability of the cosmetic formulation decreases, skin irritation increases, production cost increases, do. For example, 2 to 10% by weight.

The amount of the citric acid is 0.1 to 15% by weight based on the total weight of the cosmetic composition. When the amount of the above-mentioned citric acid is less than 0.1% by weight, the exfoliating effect of the skin is insignificant, and when it is more than 15% by weight, the stability of the cosmetic formulation is decreased and the skin irritation is increased. do. For example, 2 to 10% by weight.

The mandelic acid is contained in an amount of 0.1 to 15% by weight based on the total weight of the cosmetic composition. When the mandelic acid is contained in an amount of less than 0.1% by weight, the skin exfoliating effect is insignificant, and when it is more than 15% by weight, stability of the cosmetic formulation is decreased, skin irritation is increased, . For example, 2 to 10% by weight.

In one embodiment, the hydroxyphenyl propamidobenzoic acid is contained in an amount of 0.01 to 5% by weight based on the total weight of the cosmetic composition. When the hydroxyphenylpropamidobenzoic acid is contained in an amount of less than 0.01% by weight, the skin irritation of the cosmetic composition of the present invention is increased, and the coloring stability of the cosmetic composition is decreased when it is contained in an amount exceeding 5% by weight, Skin irritation may be rather increased. For example, 0.01 to 2.0% by weight.

In one embodiment, the gluconolactone and lactobionic acid, glycolic acid, lactic acid, citric acid, and mandelic acid may be included in a weight ratio of 1: 3 to 1:10. In the above mixed weight range, the synergistic action of the effective ingredient of the cosmetic composition of the present invention is excellent, the formulation stability is excellent, the skin irritation is low, the skin texture and the exfoliation effect can be excellent. For example, from 1: 3 to 1: 8 by weight.

One embodiment of the cosmetic composition may further comprise 0.1 to 15% by weight of tartaric acid. When tartaric acid is further contained in the above amount, the skin exfoliation efficiency can be more excellent. For example, 2 to 10% by weight.

In one embodiment, the gluconolactone, lactobionic acid, glycolic acid, lactic acid, citric acid, and mandelic acid may be included in an amount of 16 wt% to 55 wt% based on the total weight of the cosmetic composition. When the content of gluconolactone and lactobionic acid, glycolic acid, lactic acid, citric acid and mandelic acid is less than 16% by weight, the exfoliation efficiency is lowered. When the content is more than 55% by weight, skin irritation may increase have.

In another embodiment, the gluconolactone, lactobionic acid, glycolic acid, lactic acid, citric acid, tartaric acid, and mandelic acid may be included in an amount of 16 wt% to 55 wt% based on the total weight of the cosmetic composition. When included in the above content condition, exfoliation efficiency is excellent and skin irritation is small.

The cosmetic composition of the present invention can be prepared into a formulation conventionally produced in the art. In one embodiment, the cosmetic composition may be a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation, have.

In one embodiment, the cosmetic composition of the present invention is a cosmetic composition comprising an oil-in-water (O / W), a water in oil (W / O), a water in silicone -Oil (O / W / O) or Water-in-Oil-in-Water (W / O / W) formulation.

When the formulation of the present invention is a paste, cream or gel, an animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as the carrier component have.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. In the case of a spray, in particular, chlorofluorohydrocarbons, propane / Propane, such as butane or dimethyl ether.

When the formulation of the present invention is a solution or emulsion, a solvent, a solubilizing agent or an emulsifying agent is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, 3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or fatty acid esters of sorbitan.

When the formulation of the present invention is a suspension, it is possible to use, as a carrier component, a liquid diluent such as water, ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, Cellulose, aluminum metahydroxide, bentonite, agar or tracant, etc. may be used.

When the formulation of the present invention is an interfacial active agent-containing cleansing, the carrier component is selected from the group consisting of aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide ether Alkylamido betaine, aliphatic alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative, or ethoxylated glycerol fatty acid ester.

For example, the cosmetic composition of the present invention may contain at least one selected from the group consisting of polysorbate 60, sorbitan sesquioleate, stearic acid, cetyl alcohol, squalane, glycerin, butyleneglycol, arginine, carbomer, tocopheryl acetate, Diol, and purified water.

The cosmetic composition according to the present invention is harmless to the human body. It has excellent skin exfoliation and skin texture improving effect when applied to the skin, has excellent skin elasticity improvement effect such as improvement in wrinkles in the eyes, have. In particular, even when used once, it is excellent in improving the skin horny, skin texture, gloss and brightness, and is excellent in skin exfoliation and skin texture improving effect when the cosmetic composition of the present invention is used for 4 weeks or more, It has excellent dullness, eye wrinkles, elasticity, and shine improvement effect. It has excellent dermatome density, skin surface moisturizing effect, quick moisturizing effect, can improve skin brightness, improve brown spot and anti-aging.

Hereinafter, the configuration and operation of the present invention will be described in more detail with reference to preferred embodiments of the present invention. However, the following examples are provided to aid understanding of the present invention, and the scope of the present invention is not limited to the following examples. The contents not described here are sufficiently technically inferior to those skilled in the art, and a description thereof will be omitted.

Example  1 to 6 and Comparative Example  1 to 9

Using the ingredients and the contents shown in Tables 1 and 2 below, a cosmetic composition of the solubilized formulation was prepared. Specifically, Polyacrylate Crosspolymer-6 (SEPIMAX ZEN) was slowly added to purified water having the contents shown in Tables 1 and 2 below, mixed thoroughly, stirred and stirred at a temperature of 50 to 65 ° C, , All the ingredients except for the perfume were added and completely dissolved for 30 minutes. Then, the mixture was cooled to 45 캜, and perfume was added thereto in the contents of the following Tables 1 and 2, followed by solubilization. Then, the mixture was cooled to 30 DEG C and filtered to prepare a cosmetic composition.

Experimental Example  1: skin keratin measurement

Representative examples 1 and 3 and comparative example 3 among the above-mentioned examples and comparative cosmetic compositions were measured for skin exfoliating effect. Specifically, three groups of 20 subjects each were applied to the face once a day for each of Examples 1 and 3 and Comparative Example 3, and after the use, immediately after use, 2 weeks, and 4 weeks, Were taken using corneofix, a special adhesive tape, and photographed with Visioscan VC98. The subject's skin keratin was analyzed for an average keratin index (D.I) and the results are shown in Table 3 and FIG. The unit of measured skin exfoliation value is%, and D.I% is proportional to skin exfoliation degree.

FIG. 1 (b) is a photograph of skin horny skin immediately after using Example 3, FIG. 1 (c) is a skin horny skin photograph after 2 weeks of use, , Fig. 1 (d) is a photograph of skin keratin after 4 weeks of use. Referring to Table 3 and FIG. 1, it was found that the skin exfoliation effect was excellent when the cosmetic composition of the present invention was applied.

Test Example  2. Measurement of skin texture

The skin texture was measured for Example 3 and Comparative Example 4 as representative examples of the above-mentioned Examples and Comparative Examples. Specifically, two groups of 20 subjects were applied to the face, and Example 3 and Comparative Example 4 were applied to the face once a day. Immediately after use, immediately after use, after 2 weeks and 4 weeks, Antera 3D. The average roughness (Ra, average roughness) was analyzed through photographed photographs, and the results are shown in Table 4 and FIG.

In Table 4, the skin roughness value (Ra) is in inverse proportion to the skin texture, and skin texture is improved as the skin roughness is reduced. 2 (b) is a photograph of a face part (ball) immediately after using the embodiment 3, and Fig. 2 (c) is a photograph of a face part FIG. 2 (d) is a photograph of the face area (ball) after 4 weeks of use. Referring to Table 4 and FIG. 2, it was found that the skin roughness (skin texture) improvement effect was excellent when the cosmetic composition of the present invention was applied.

Test Example  3: Measurement of skin melanin

Skin melanin content was measured for Examples 1 and 3 and Comparative Example 2 as representative examples of the above-mentioned Examples and Comparative Examples. Specifically, Examples 1 and 3 were applied to the face in three groups of 20 subjects, and skin melanin content of the hyperpigmented areas of the subject's face before use, immediately after use, 2 weeks, and 4 weeks Were measured using a Mexameter. The average value of the melanin values measured three times was analyzed and the results are shown in Table 5 below. The unit of skin melanin index is M.I (Melanin Index), and the degree of skin melanin content is proportional to M.I value.

Referring to the results of Table 5, it was found that the effect of reducing the skin melanin content was excellent when the cosmetic composition of the present invention was applied.

Test Example  4: Measurement of skin irritation

The degree of staining (pigment deposition) in the skin was measured for Example 3 as a typical example among the above-mentioned Examples and Comparative Examples. Specifically, 50 subjects were applied to the face once a day, and the entire subjects were photographed using Janus Ⅰ Mark Ⅱ before, after, 2 weeks, and 4 weeks after use. The degree of pigmentation of the UV mode image was analyzed and the results are shown in Table 6 below. The measured skin pigmentation unit is%, and the average skin pigmentation degree of the analysis area is shown in 100% of the total, and the percentage value and the degree of skin pigmentation are proportional.

Referring to the results shown in Table 6 above, it was found that the effect of improving the shine in skin (shading) was excellent when the cosmetic composition of the present invention was applied.

Test Example  5: Eye wrinkle measurement

The wrinkles of the eyes were measured for Example 3 as a representative example of the above-mentioned Examples and Comparative Examples. Specifically, Example 3 was applied to the face once a day for 50 subjects, and the wrinkles of the eye area of the subject's face before, after, 2 weeks, and 4 weeks after use were photographed using Antera 3D. The degree of wrinkles was analyzed by specifying a specific region of the photographed photograph, and the results are shown in Table 7 and FIG. The measured wrinkles are overall size and the analytical value is inversely proportional to the degree of wrinkle improvement.

Fig. 3 (b) is a picture of eye wrinkles after 2 weeks of use of Example 3, Fig. 3 (c) is a photograph of eye wrinkles after 4 weeks of using Example 3, It is an eye-wrinkled photo. Referring to the results of Table 7 and FIG. 3, it was found that the effect of improving the skin wrinkles was excellent when the cosmetic composition of the present invention was applied.

Test Example  6: skin elasticity measurement

Skin elasticity was measured for Example 3 and Comparative Example 5 as representative examples of the above-mentioned Examples and Comparative Examples. Specifically, two groups of 20 subjects were applied to the face once a day for Example 3 and Comparative Example 5, and the skin of the face portion of the subject's face was measured with a cutometer before use, immediately after use, 2 weeks and 4 weeks The results are shown in Table 8 below. Among the measured variables, R2 value was used as ball elasticity evaluation data. The unit of measured ball elasticity is A.U (Arbitrary Unit), and the measured value of R2 is proportional to the elasticity of skin.

Referring to the results of Table 8, it was found that the skin elasticity improving effect was excellent when the cosmetic composition of the present invention was applied.

Test Example  7: Skin gloss measurement

As a representative example of the above-mentioned Examples and Comparative Examples, skin gloss was measured in Example 3. [ Specifically, 50 subjects were applied to the face once a day, and skin gloss of the subject's face was measured using a glossmeter before use, immediately after use, 2 weeks, and 4 weeks. The average values measured for each 3 times are shown in Table 9 below. The measured unit of skin gloss is SGU (Skin Gloss Unit), and the measured value is proportional to the degree of skin gloss.

Referring to the results shown in Table 9, it was found that the cosmetic composition of the present invention was superior in improving skin luster.

Test Example  8: Measurement of dermal density

Representative examples of the cosmetic compositions of the examples and comparative examples were measured for dermal density of the dermis in Example 3. Specifically, 50 subjects were applied to the face once a day, and the dermal density of the subject's face was measured by Skin Scanner USB before use, immediately after use, 2 weeks, and 4 weeks, Are shown in Table 10 and FIG. The measured dermal density is in%, and the measured value is in proportion to the dermal density.

4 (b) is a photograph of the dermal density of the skin after 2 weeks of use of Example 3, and Fig. 4 (c) is a photograph of the dermal density of the skin of Example 3 After 4 weeks of use, the skin is a densely packed photograph. Referring to the results of Table 10 and FIG. 4, it was found that the effect of improving the dermal density was excellent when the cosmetic composition of the present invention was applied.

Test Example  9: Measurement of skin moisture content

Representative examples of the above-mentioned Examples and Comparative Examples were the skin moisture content of Example 3. Specifically, Example 3 was applied to the face once a day for 50 subjects, and the skin moisture content on the face of the subject's face was measured before use, immediately after use, 2 weeks, and 4 weeks using Corneometer 825 . The average values measured three times are shown in Table 11 below. The measured skin moisture content is A.U (Arbitrary Unit), and the measured value is proportional to the skin moisture content.

Referring to the results of Table 11, it was found that the skin moisture content was increased when the cosmetic composition of the present invention was applied.

Test Example  10: Moisture measurement in skin

As a representative example of the above-mentioned Examples and Comparative Examples, the amount of water in the skin (dermis) was measured in Example 3. [ Specifically, 50 subjects were applied to the face once a day, and the moisture content (dermis) in the skin of the subject's face before, after, 2 weeks, and 4 weeks after use was measured by Moisture D Lt; / RTI > The average values measured three times are shown in Table 12 below. The measured moisture content of the skin is%, and the measured value is proportional to the skin moisturizing.

Referring to the results of Table 12, it was found that the skin moisture content was increased when the cosmetic composition of the present invention was applied.

Test Example  11. Skin brightness measurement

Representative examples of the above-mentioned examples and comparative cosmetic compositions were measured for skin brightness in Example 3. The skin brightness was measured in 50 subjects. Example 3 was applied to the face once a day. The skin brightness of the subject's face was measured before use, immediately after use, 2 weeks, and 4 weeks using a Chromameter CR400 Respectively. The average value of the L * (Lightness) value, which is the brightness index measured three times, was analyzed and the results are shown in Table 13 below. The degree of skin brightness and L * value are proportional.

Referring to Table 13, it was found that the skin brightness improvement effect was excellent when the cosmetic composition of the present invention was applied.

Test Example  12: Skin Brown Spot  Measure

A skin-colored spot was measured for Example 3 as a typical example among the above-mentioned Examples and Comparative Examples. The skin-brown spot degree of the pigmentation site was measured in 50 subjects. Example 3 was applied to the pigmentation area of the face once a day. After the use, immediately after use, 2 weeks and 4 weeks, The pigmentation sites were photographed. Melanin levels were analyzed by specifying specific regions of the photographed photographs, and the results are shown in Table 14 below. The measured melanin level is the average level and the analysis value is inversely proportional to the melanin level, which means that the lower the assay value, the better the melanin level of the brown spot.

Referring to Table 14, it was found that the skin pigmentation improving effect was excellent when the cosmetic composition of the present invention was applied.

Test Example  13: Results of Questionnaire Evaluation

The subjects of the present invention were 50 subjects, and the results were as follows: improvement of skin horny, improvement of skin pigmentation, improvement of skin texture, improvement of skin wrinkles, improvement of skin elasticity, improvement of skin brightness, The degree of inclination and overall satisfaction were evaluated, and the results are shown in Table 15 below. For the examples 1 to 6 and the comparative examples 1 to 7, skin irritation degree, dermis density improvement, skin texture improvement, exfoliation effect, and application time (use time) The results of evaluation are shown in Fig.

5 and 15, when the cosmetic composition of the present invention is applied, improvement of skin horny, skin pigmentation, improvement of skin texture, improvement of skin wrinkle, improvement of skin elasticity, Brightness, feeling, feelings, and overall satisfaction were all excellent. As shown in FIG. 5, the cosmetic compositions of Examples 1 to 6 exhibited dermal density improvement, skin texture and exfoliation removal effect even when applied for a shorter time than Comparative Examples 1 to 7, and skin irritation Very low.

Test Example  14: Test Subject Questionnaire Evaluation Result

When the cosmetic compositions of Examples 1 to 6 and Comparative Examples 1 to 9 were used, a skin patch test was conducted to examine the skin irritation test. The subjects were selected as those who had no skin disease at the test sites of 50 to 70 years old and were performed on 10 persons. The upper part of the patch area was wiped with 70% ethanol and dried. Then, 0.1 g of each of the above example and comparative example cosmetic composition was applied to the skin for 24 hours, and the skin reaction was checked within 1 hour after removing the patch, 48 hours after the start of the patch). Skin response determinations were made according to the following test criteria. The skin patch test results are shown in Table 16 below.

* Skin reaction test standard

-: No reaction ±: Very weak positive (erythema) +: Positive (erythema) ++: Strong positive (erythema, edema) +++: Severe positive (erythema, edema, blister)

Referring to the results of Table 16, it was found that the skin cosmetic compositions of Examples 1 to 6 of the present invention had little skin irritation as compared with Comparative Examples 1 to 9. In particular, skin irritation was significantly increased in Comparative Examples 1 and 2, which were applied in excess of the hydroxy acid content of the present invention, and Comparative Example 4, in which the hydroxyphenylpropamidobenzoic acid was used in excess.

Test Example  15: Formulation stability evaluation

In order to measure the stability of the cosmetic compositions of Examples 1 to 6 and Comparative Examples 1 to 9 with respect to the degree of separation and discoloration degree, a thermostat kept constant at 45 ° C and 25 ° C, and a refrigerator kept constant at 4 ° C, , The composition of the examples and the comparative examples was placed in a sample container and stored for 8 weeks, and the degree of separation and discoloration was comparatively measured. The results are shown in Table 17 below. The degree of separation and discoloration of the product was classified into the following six grades and evaluated.

* Separation and discoloration evaluation criteria

0: No change 1: Extremely slight separation (discoloration) 2: A little separation (discoloration) 3: A little severely discoloration 4:

Referring to the results of Table 17 above, it was found that the cosmetic compositions of Examples 1 to 6 were superior in formulation stability to the cosmetic compositions of Comparative Examples 1 to 9 because of less discoloration and separation phenomenon.

It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (6)

0.1 to 15% by weight of gluconolactone, 0.1 to 15% by weight of lactobionic acid, 0.1 to 15% by weight of glycolic acid, 0.1 to 15% by weight of lactic acid, A cosmetic composition comprising 0.1 to 15% by weight of citric acid, 0.1 to 15% by weight of mandelic acid and 0.01 to 5% by weight of hydroxyphenyl propamidobenzoic acid as an active ingredient .
The cosmetic composition according to claim 1, wherein the gluconolactone, lactobionic acid, glycolic acid, lactic acid, citric acid, and mandelic acid are contained in a weight ratio of 1: 3 to 1:10.
The cosmetic composition according to claim 1, wherein the gluconolactone and lactobionic acid, glycolic acid, lactic acid, citric acid and mandelic acid are contained in an amount of 16 to 55% by weight based on the total weight of the cosmetic composition .
The cosmetic composition according to claim 1, further comprising 0.1 to 15% by weight of tartaric acid based on the total weight of the cosmetic composition.
The cosmetic composition according to claim 1, wherein the cosmetic composition is a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing oil, powder foundation, emulsion foundation, wax foundation, ≪ / RTI >
The cosmetic composition according to claim 1, wherein the cosmetic composition is at least one selected from the group consisting of Oil-in-Water (O / W), Water-in-Oil (W / O), Water-in- -Oil (O / W / O) or Water-in-Oil-in-Water (W / O / W) formulation.

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