KR20160069857A - Compositions and methods for increasi ng telomere activity - Google Patents

Abstract

The present invention relates to a composition for increasing telomeric activity and a method of preparing the composition, and more particularly, to a composition for preventing and treating skin aging The present invention relates to a composition for increasing telomeric activity that promotes cell division, promotes cell division, increases immunity of skin and promotes antioxidative action, and a method for producing the composition. The present invention relates to a method for producing a composition comprising berry-extracted MF (microfarad) It is characterized in that it is composed of acrylate, purified water, sodium hyalulonate, niacinamide, adenosine, tromethamine, hyssop extract, Earthie extract, cherry pine fruit extract and spherical berry granules.

Description

Technical Field [0001] The present invention relates to a composition for increasing telomeric activity,

The present invention relates to a composition for increasing telomeric activity and a method of preparing the composition, and more particularly, to a composition for preventing and treating skin aging The present invention relates to a composition for increasing telomeric activity that promotes cell division, promotes cell division, increases immunity of skin, and promotes antioxidative action, and a method for producing the composition.

Telomere (telomere) is a piece of DNA that serves as a cell clock. Telomir is a compound word of the Greek 'telos' and 'meros'. Enzymes that replicate chromosomes and DNA during cell division can not continue cloning to the end of the chromosome.

If the cell divides without telomeres, the end of the chromosome containing information about the cell will be lost. Telomere is an undissociated buffer zone that blocks the end of a chromosome. However, as the cells divide, the telomeres disappear and are supplemented by the telomerase enzyme telomerase.

The length of telomere varies greatly depending on species. In yeast, it is composed of 300 to 600 base pairs. In humans, it is composed of several kilobases (length units of nucleic acid sequences such as DNA). In humans, as the length of the telomere is shortened, it may cause aging which prevents cell division.

In order to activate the telomere having the above-mentioned effect, conventionally, it has been used under the name of night pack and sleep pack. These conventional night packs or sleeping packs have a high sticky feel due to their high viscosity. By using a surfactant and oil, they form a film on the skin to block the pores, thereby preventing skin respiration, There is a problem that it causes disturbing and consequently rash skin.

Korean Patent Publication No. 2011-89887. Korean Patent Publication No. 2013-137252. Korean Patent Publication No. 2008-74258.

SUMMARY OF THE INVENTION The present invention has been made in view of the foregoing problems, and it is an object of the present invention to provide a skin care cosmetic composition which prevents film formation of a skin without using a surfactant and oil to facilitate waste discharge and nutrient supply, The present invention relates to a composition and a composition for enhancing telomeric activity which have an antioxidative effect by metabolism and have an effect of preventing skin aging, inhibiting cell senescence of pores, having a skin soothing and moisturizing effect, And a method of manufacturing the same.

It is an object of the present invention to provide a composition for increasing telomeric activity, which comprises a microfarad extract of berries and a microcapsule containing carbomer, sodium polyacrylate, purified water, sodium hyaluronate, niacinamide, adenosine, tromethamine, Wherein the extract is selected from the group consisting of extracts, eyebrow extracts, extracts, eyebrows extracts, extracts of mustard seeds, extracts of pine berry, and spherical berry grenules.

The berry granules are prepared by mixing lactose, microcrystalline Lentellulose, tocopheryl acetate, Waxy extract, Earthie extract, Lycopersiconate fruit extract, and Klucel LF (HPC-LF) 4% Soln in Berry Complex. Lt; RTI ID = 0.0 > telomeric < / RTI > activity.

Wherein the size of the berry grenules is 0.5 to 1.5 mm.

The micro fludizer may be selected from the group consisting of ginseng fruit extract, purified water, ginseng extract, ginseng extract, green tea extract, aloe-oligopeptide-1, cabbage leaf extract, rice bran extract, tomato extract, Extracts, Cucumber Extracts, Gugija Extracts, Bokbunja Extracts, Aronia Extracts, Odi Extracts, Blueberry Extracts, Omiza Extracts, Corn Oil Extracts, Strawberry Extracts, Manganese Extracts, Ginger extract of the present invention.

Wherein the viscosity of the berry-extracted microfludizer is 11,000 to 15,000 (5 s / 20 rpm) and the pH is 5.0 to 7.0.

And the particle size of the berry-extracted MF is 120 to 240 占 퐉.

In order to accomplish the object of the present invention, there is provided a method for preparing a composition for increasing telomeric activity, comprising: a berry extract MF preparation step; A berry granule preparation process; A process for forming a mixture A in which berry extract MF is mixed with a carbomer, sodium polyacrylate, purified water and sodium hylauronate to form mixture A; Berry Extract Mixture B of MF and niacinamide B and Berry Extract Mixture of MF and adenosine C, Berry Extract Mixture D of MF and tromethamine and a mixture E of purified water, waxy extract, Earthie extract, A mixture preparation process; And mixing the mixture A, B, C, D, E and spherical berry granules with stirring to obtain a composition for increasing telomeric activity.

The berry granules were prepared by mixing a first mixture prepared by mixing lactic acid and microcrystalline rinse cellulose with warm mixture, a second mixture formed by mixing tocopheryl acetate, hanami extract, Earthie extract, and pine nut extract, Klucel LF ((HPC- (HPC-LF) 4% Soln in Berry Complex) was mixed with the first mixture and the second mixture in an amount of 40% by weight based on the mixing amount of the first mixture and the second mixture. Lt; RTI ID = 0.0 > telomeric < / RTI > activity.

The present invention uses natural materials and does not use a surfactant and oil to prevent skin film formation, thereby enabling the skin to breathe. Therefore, since the waste material is made of waste materials and a low-molecular-weight component, And has excellent antioxidative effect by active metabolism to suppress aging of skin and inhibit cell aging of pores, and has a function of cleansing, moisturizing, and whitening skin, and thus maintaining a clean skin. And a method for producing the composition.

BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a process diagram showing a method for preparing a composition for increasing telomeric activity to which the technology of the present invention is applied. Fig.
2 is a graph showing the extent to which the liquid berry extract MF of the present invention is absorbed into the skin.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.

The composition for increasing the telomeric activity of the present invention can be obtained by extracting beryl extracted MF (microfarad) with carbomer, sodium polyacrylate, purified water, sodium hyaluronate, niacinamide, adenosine, tromethamine, A perilla extract, a perennial berry extract, and a spherical berry granule.

When the size of the berry granules is less than 0.5 mm, the massage (scrub) function is deteriorated. When the size of the berry granules is less than 1.5 mm, There is a problem of sinking at the present formulation viscosity, and it is preferably 0.85 to 1.2 mm.

As shown in FIG. 1, the method of manufacturing a composition for increasing telomeric activity according to the present invention is characterized in that it comprises a ginseng fruit extract, purified water, antioxidant activity, antioxidant activity, Ginseng extract, which protects against aging of skin and protects against cell senescence, ginseng extract which contains a large amount of saponin to protect against skin aging, ginseng extract with anti-aging effect, green tea extract with DNA-reinforcing component, garlic extract, ginger extract Leaf extract, Rice bran extract, Tomato extract, Seaweed extract, Carrot extract, Broccoli extract, Cucumber extract, Gugija extract, Bokbunja extract, Glycyrrhiza uralensis extract, Aronia extract, Audi extract, Blueberry extract, Omija extract, Corn oil extract, (MF) preparation step (S100) of a berry extract MF (microfludizer), which is a mixture of a strawberry extract, a mushroom extract, a western scarlet raspberry extract, a royal rosemary extract and a fig extract.

The viscosity of the berry-extracted MF (microfarad) is in the range of 11,000 to 15,000 (at a temperature of 40 to 80 ° C for 10 minutes) at a rotation speed of 60 rpm after mixing the raw materials extracted at low temperatures into the tank. 5s / 20 rpm), a PH of 5.0 to 7.0, and a particle size of 120 to 240 mu m.

When the viscosity of the berry extract MF is less than 11,000 (5s / 20 rpm), there is a problem that the produced granules sink. When the viscosity is 15,000 (5s / 20 rpm) or more, the berry extract MF and the granule There is a problem of cracking.

On the other hand, the particle size of berry-extracted MF is 120 to 240 탆. This is because the particle size can be easily absorbed into the skin as shown in FIG. 2 attached hereto.

The berry extract MF has a high anthocyanin component which acts as an antioxidant, promotes cell division, and is excellent in anti-aging, anti-inflammatory effect, skin soothing, protection effect and various vitamins.

In addition, it is rich in saponin content, so it has excellent antioxidant effect, prevents aging of cells in the body, penetrates into the skin to prevent skin aging and breathes, and exerts excellent influences. In addition, it contains a lot of natural complex vitamins (A, B1, B2, B6, C, D, E, K, P) and gives skin's immunity enhancement and soothing moisture.

As described above, when the preparation of the berry-extracted MF is completed, the berry-extracted MF (microfarad), the thickening agent Carbomer, and the skin conditioning agent sodium polyacrylate are dissolved in purified water used as a solvent to form a mixture A A forming process S200). At this time, the melting condition is a rotational speed of 60 rpm, a heating temperature is 80 DEG C, and a heating time is 30 minutes.

As described above, when the preparation of berry extract MF is completed, a mixture B of berry extract MF and niacinamide, a mixture C of berry extract MF and adenosine, a mixture D of berry extract MF and tromethamine, purified water, A mixture preparation step (S400) of preparing a mixture E of berry extract MF and berry extract MF is carried out.

Meanwhile, the berry granule preparation step (S300) can be performed at the same time. As described above, when the preparation of the berry-extracting MF is completed, a process A (S200) of forming a mixture A in which the berry-extracted MF and the carbomer, sodium polyacrylate, purified water and sodium hyaluronate are dissolved by heating to form the mixture A, .

When the preparation of the mixture A, B, C, D, E and spherical berry granules is completed, a mixing step (S500) of placing the mixture in a tank and stirring and mixing is performed to prepare a composition.

The composition ratio of the composition of the present invention prepared by the above method is such that mixture A of 74% by weight, mixture B of 7.00% by weight, mixture C of 2.04% by weight, mixture D of 2.40% by weight, mixture E of 13.60% by weight and berry granules of 1.10% do.

The blend ratio of the individual raw materials constituting the mixtures is 66.39% by weight of berry extract MF, 0.40% by weight of carbomer, 0.10% by weight of sodium polyacrylate as skin conditioning agent, and 6.93% by weight of purified water.

On the other hand, in the composition of each mixture, mixture B contained 5.00% by weight of berry extract MF and 2.00% by weight of niacinamide, mixture C was 2.00% by weight of berry extract MF, 0.04% by weight of adenosine, 2.00% 0.40% by weight of methamine, 0.35% by weight of purified water, 0.05% by weight of water extract, 0.05% by weight of earth extract, and 13.10%

The berry grenules consisted of 1.0% by weight of tocopheryl acetate, 0.35% by weight of purified water, 0.05% by weight of horseradish extract, 0.05% by weight of Asnuria extract, a mixture of 74.40% by weight of lactose and 25.00% by weight of microcrystalline cellulose, (HPC-LF) 4% Soln in Berry Complex) was mixed with the first mixture and the second mixture was mixed with 0.05% by weight of the first mixture and the second mixture, And 40 wt% of Klucel LF ((HPC-LF) 4% Soln in Berry Complex) was added to the total mixture amount of the mixture.

As a method for producing a berry granule having a spherical shape having a predetermined size, 74.40% by weight of lactose and 25.00% by weight of microcrystalline cellulose were mixed and stirred at 80 rpm for 30 minutes at 60 rpm. When the first mixture was prepared, a second mixture formed by mixing 1.0% by weight of tocopheryl acetate, 0.35% by weight of purified water, 0.05% by weight of horseradish extract, 0.05% by weight of Earther extract and 0.05% And stirred at 80 rpm for 30 minutes at 60 rpm.

In more detail, the method for producing the berry granules having the spherical morphology will be described in detail. First, Lactose, a vegetable moisturizer, and microcrystalline cellulose, a scrubbing agent, are mixed with hydroxypropylcellulose having an active ingredient and a binder component. Hydroxypropylcellulose is mixed and a small lump (seed) is obtained using a mixing machine.

The small lumps are first classified using a 1.5 mm mesh (sieve), and then classified using a 0.5 mm mesh (sieve) to obtain uniform small lumps (seeds) of 0.5 to 1.5 mm.

A bead (0.5 mm to 1.5 mm bead) is obtained by beading (forming a sphere) using a granulator (bead former) and then selecting the size using the above mesh The selected beads are dried at 50 ° C for about 18 hours to obtain grains having a dry weight loss of 20% or less.

The present invention uses natural materials and does not use a surfactant and oil to prevent skin film formation, thereby enabling the skin to breathe. Therefore, since the waste material is made of waste materials and a low-molecular-weight component, It is easy to use, has excellent antioxidative effect by active metabolism, and has a useful effect of preventing aging of skin and inhibiting cell aging of pores, maintaining skin clean, moisturizing and whitening effect, to be.

S100: Berry extraction MF preparation process S200: Mixture A formation process
S300: Berry granulation preparing process S400: Mix preparation process
S500: Mixing process

Claims (8)

A composition for increasing telomeric activity,
Berry Extract MF (microfarad) and Carbomer, sodium polyacrylate, purified water, sodium hyaluronate, niacinamide, adenosine, tromethamine, hiruma extract, earth extract, ≪ / RTI > wherein the composition is made of granules.
The method according to claim 1,
The berry granules are prepared by mixing lactose, microcrystalline Lentellulose, tocopheryl acetate, Waxy extract, Earthie extract, Lycopersiconate fruit extract, and Klucel LF (HPC-LF) 4% Soln in Berry Complex. ≪ / RTI > to increase telomer activity.
The method according to claim 1,
Wherein the size of the berry grenules is 0.5 to 1.5 mm.
The method according to claim 1,
The microfarad extracts of the berry extracts were obtained from ginseng fruit extract, purified water, pine nut extract, green tea extract, aloe-oligopeptide-1, cabbage leaf extract, rice bran extract, tomato extract, nettle leaf extract, carrot extract, broccoli extract, , Gugija Extract, Bokbunja Extract, Aronia Extract, Odie Extract, Blueberry Extract, Omija Extract, Corn Oil Extract, Strawberry Extract, Manganese Extract, Western Hawthorn Extract, Youngsil Extract, Fig Extract, Garlic Extract and Ginger Extract Lt; RTI ID = 0.0 > telomeric < / RTI > activity.
The method according to claim 1,
Wherein the berry-extracted MF has a viscosity of 11,000 to 15,000 (5 s / 20 rpm) and a pH of 5.0 to 7.0.
The method according to claim 1,
Wherein the particle size of berry-extracted MF is 120 to 240 탆.
A method for preparing a composition for increasing telomeric activity,
Berry extraction MF preparation process;
A berry granule preparation process;
A process for forming a mixture A, wherein the berry extract MF is dissolved by heating the carbomer, sodium polyacrylate, purified water and sodium hylauronate to form a mixture A;
Berry Extract Mixture B of MF and niacinamide B and Berry Extract Mixture of MF and adenosine C, Berry Extract Mixture D of MF and tromethamine and a mixture E of purified water, waxy extract, Earthie extract, Mix preparation process
And mixing the mixture A, B, C, D, E and spherical berry grenules with stirring to obtain a composition for increasing telomeric activity.
8. The method of claim 7,
The berry granules were prepared by mixing a first mixture prepared by mixing lactic acid and microcrystalline rinse cellulose with warm mixture, a second mixture formed by mixing tocopheryl acetate, hanami extract, Earthie extract, and pine nut extract, Klucel LF ((HPC- (HPC-LF) 4% Soln in Berry Complex) was mixed with the first mixture and the second mixture in an amount of 40% by weight based on the mixing amount of the first mixture and the second mixture. A method for preparing a composition for increasing telomeric activity.

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