KR20160001316A - Fabrication method of patient customized Implant using 3D imaging technology - Google Patents

Abstract

The present invention relates to the manufacture of implants, and more particularly, to manufacture a patient-customized implant to solve the problem of a limited-size implant, and in particular, to identify the characteristics of various medical devices so as to measure the exact size of the affected part, A patient-tailored implant model using 3D imaging technology that collects image information data (MRI, CT, X-RAY, etc.) and makes customized implant model through 3D design program on computer using this 3D imaging technology ≪ / RTI >
The feature of the present invention is that a two-dimensional data according to a predetermined anatomical implant model is extracted from medical imaging data taken by a medical image photographing apparatus, and data of a three-dimensional model is generated from data of the extracted two- Dimensional model data through data processing for generating three-dimensional implant data, and generating three-dimensional implant image data by using the generated three-dimensional model data to produce a three-dimensional implant model.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method of making a patient-customized implant using a 3D imaging technique,

The present invention relates to the manufacture of implants, and more particularly, to manufacture a patient-customized implant to solve the problem of a limited-size implant, and in particular, to identify the characteristics of various medical devices so as to measure the exact size of the affected part, The method of creating the implant model through the 3D imaging data which collects the image information data (MRI, CT, X-RAY, etc.) and makes the customized implant model through the 3D design program on the computer using this 3D imaging technique .

In general, implants have been developed to minimize the inconvenience in human life by replacing human bones or teeth with artificial ones.

In these implants, implants of other parts of the body, except for the current tooth implants, were imported from the United States, Germany, and the like only several years before.

In other words, tooth implants are relatively easy to make and have many production techniques and equipment. Implants other than teeth, however, are not only difficult to produce data for the shape, but also lack devices and techniques for actual production.

 Recently, the implant was successfully manufactured in the mother hospital in Seoul. However, most of the implants have very limited specifications, ranging from 3 to 5 types.

On the other hand, since most implants are not patient-tailored implants, implants of this standard are not only bad for the individual patient, but they can also cause side effects. In other words, except for some cases where the standard is limited, most implants are difficult to provide precisely the ones that fit the patient.

Therefore, there is a desperate need for a technology that can provide an implant model suitable for the affected part of the patient.

Patent Application No. 10-2009-0072743 Patent Application No. 10-2012-0011069 Patent Application No. 10-2012-0018032 Patent Application No. 10-2013-0142146

In order to solve the above problems, it is an object of the present invention to manufacture a patient-customized implant to solve the problem of the implant having a limited standard.

Another object of the present invention is to acquire image information data (MRI, CT, X-ray, etc.) of the affected part by finding the characteristics of various medical instruments so as to measure the exact size of the affected part, And to create a customized implant model through a 3D design program on the computer.

It is a further object of the present invention to provide a patient-tailored optimized implant model by calculating image information data for precise three-dimensional modeling suited to the affected part through the medical imaging information.

According to an aspect of the present invention, there is provided a medical imaging system, comprising: extracting two-dimensional data according to a predetermined anatomic implant model from medical imaging data captured by a medical imaging apparatus; Dimensional model data through data processing to generate three-dimensional implant data, and generating image data for three-dimensional implant production using the generated three-dimensional model data to produce a three-dimensional implant model The present invention provides a method of making a patient-customized implant model using a 3D imaging technique.

In a preferred embodiment of the present invention, a medical image photographing information processing step of receiving, receiving, processing, and storing image information photographed by a medical image photographing apparatus, Dimensional medical image data through data processing for extracting two-dimensional data according to a predetermined anatomical implant model by reading the stored medical imaging data and generating three-dimensional model data from the extracted two-dimensional model data, An image information extracting step of generating data; A 3D image data generation step of generating image data for three-dimensional implant preparation for model building using the generated 3D model data; And transmitting the image data for three-dimensional implant manufacturing to an implant model making apparatus, and preparing an implant model. The present invention also provides a method of manufacturing a patient-customized implant model using 3D imaging technology.

In a preferred embodiment of the present invention, the image information extracting step includes: a two-dimensional image information extraction step of reading stored medical image sensing data and extracting two-dimensional data according to a predetermined anatomical implant model; And a three-dimensional image information extracting step of generating three-dimensional model data through data processing for generating three-dimensional model data from the extracted two-dimensional model data. And a method of making a patient-customized implant model using the method.

In a preferred embodiment of the present invention, in extracting the two-dimensional image data from the medical image capturing data, the extraction is performed through Radon transformation, and in the three-dimensional image information extracting step, The present invention provides a method of manufacturing a patient-customized implant model using a 3D imaging technique, characterized in that the 3D model data is extracted from the data by inverse transformation of Radon Transform.

In a preferred embodiment of the present invention, two-dimensional data according to a predetermined anatomical implant model is extracted from medical imaging data shot by a medical imaging apparatus, data is extracted from the extracted two-dimensional model data Dimensional image data is generated through data processing for generating a three-dimensional model data, and image data for three-dimensional implant production is generated using the generated three-dimensional model data. Implant modeling system is provided.

In a preferred embodiment of the present invention, a medical image capturing information processing unit for receiving, receiving and processing image information photographed by a medical image capturing apparatus and storing the received image information in a storage unit; Dimensional medical image data through data processing for extracting two-dimensional data according to a predetermined anatomical implant model by reading the stored medical imaging data and generating three-dimensional model data from the extracted two-dimensional model data, An image information extracting unit for generating data; A 3D image data generation unit for generating image data for three-dimensional implant preparation for model building using the generated 3D model data; And an implant model information processing unit for transferring the image data for three-dimensional implant manufacturing to the implant model making apparatus so that the implant model can be manufactured. The present invention also provides a patient-customized implant model making system using the 3D image technique.

In a preferred embodiment of the present invention, the image information extracting unit includes: a two-dimensional image information extracting module for extracting two-dimensional data according to a predetermined anatomical implant model by reading stored medical image sensing data; And a three-dimensional image information extracting module for generating three-dimensional model data through data processing for generating three-dimensional model data from the extracted two-dimensional model data. The present invention provides a system for creating a patient-customized implant.

In a preferred embodiment of the present invention, in extracting the two-dimensional data from the medical imaging data, the two-dimensional image information extracting module extracts the extracted two-dimensional data through Radon transformation, and in the three- The present invention provides a patient-customized implant modeling system using a 3D imaging technique, wherein 3D model data is extracted from the data by inverse transformation of Radon Transform.

In order to solve the problem of the implant having a limited standard, the patient-customized implant can be manufactured so that a customized artificial joint is provided for each individual patient so as to have an excellent fit, There is an effect that can be achieved.

Another effect of the present invention is to acquire the image information data (MRI, CT, X-ray, etc.) of the affected part by determining the characteristics of various medical devices so as to measure the exact size of the affected part, And to create a customized implant model through a 3D design program on the computer.

In particular, another effect of the present invention is to provide a patient-tailored optimized implant model by calculating image information data for precise three-dimensional modeling matching the affected part through the medical imaging information, .

In addition, the present invention can save time and cost in re-manufacturing, and can be manufactured in a patient-customized manner to increase the life span of the artificial joint.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a diagram illustrating an example of an overall procedure for manufacturing an implant model according to the present invention; FIG.
FIG. 2 is an explanatory diagram for explaining a two-dimensional image information extraction technique during image information extraction in the method of manufacturing an implant model according to the present invention.
FIG. 3 is a photograph showing an example that can be applied to each step in the method of manufacturing an implant model according to the present invention.
FIG. 4 is a view illustrating an example of a process of performing a Radon Transform transformation process using two-dimensional data from Raw Data in the method of manufacturing an implant model according to the present invention.
FIG. 5 is a view illustrating an example of a process of inverse transformation of a Radon Transform with three-dimensional data in the method of manufacturing an implant model according to the present invention.
FIG. 6 is an exemplary view showing processing of 3D design data in the method of manufacturing an implant model according to the present invention.
FIG. 7 is a diagram illustrating an overall configuration of an implant model production system according to the present invention.
8 is a flowchart of a method of manufacturing an implant model according to the present invention.

Hereinafter, the present invention will be described in detail with reference to the accompanying drawings.

That is, a method of manufacturing an implant model such as a knee joint using 3D imaging data according to the present invention and a system 10 for manufacturing an implant model, as shown in FIGS. 1 to 8, include a CT imaging device, an MRI imaging device, And to produce an implant model using the medical imaging data photographed by the imaging device 100.

Implant models made to replace the human joints are easy to extrude into the outside as well as to estimate the shape and ease of treatment. However, there are many cases in which it is difficult to know the implant model as easily as the bone, but the treatment is not easy.

For example, the knee (knee joint) knee to the knee to the back functioning to bend the knee from the edge of the bottom of the femur, starting at the edge of the tibia is attached to the edge. In addition, strengthening of the bones is strengthened by many strong ligaments, including the medial and lateral collateral ligaments, and the sphincter ligaments within the joints, as well as their direction and range of motion. The knee joint is the largest joint in our body and very unstable joint. It is the surrounding ligaments and muscles that maintain the stability of this unstable joint. These knee joints are easily damaged by traffic accidents, sports injuries, etc. Knee injuries caused by sports can result in bone fractures, surrounding ligaments, or cartilage rupture in the knee. It is an important factor in the treatment of knee joints to accurately shape and produce an important implant model such as the knee joint.

Therefore, in order to produce bone implants as important as the knee joints, the implant model preparation method and the implant model production system 10 using the 3D contrast data according to the present invention can be customized by using the medical image data And the implants are implanted.

That is, the medical imaging device 100 extracts two-dimensional data according to a predetermined anatomical implant model from the medical imaging data captured by the medical imaging device 100, and performs data processing for generating three-dimensional model data from the extracted two- Dimensional model data is generated by a three-dimensional image processing method (Data Processing), and image data for three-dimensional implant production is generated using the generated three-dimensional model data. An implant for implanting a patient- And a model making system (10).

In addition, the implant model making system 10 extracts two-dimensional data according to a predetermined anatomical implant model from the medical imaging data taken by the medical imaging apparatus 100, and extracts three-dimensional data from the extracted two- 3D model data is generated through data processing to generate 3D model data, and image data for 3D implant preparation is generated using the generated 3D model data to produce a 3D implant model And a method of manufacturing a patient-customized implant model using the 3D imaging technique.

Hereinafter, an implant model making system 10 and an implant model making method according to the present invention will be described in detail.

A medical image photographing information processing unit 20 for receiving the received image information from the medical image photographing apparatus 100, receiving the processed image information, and storing the received image information in the storage unit. The medical image capturing information processing unit 20 receives and processes the medical image capturing data of the human body transmitted from the medical image capturing apparatus 100, and is stored in the data storage unit.

In the method of manufacturing an implant model, a medical image capturing information processing step S20 (S20) of receiving medical image capturing information from the medical image capturing apparatus 100 by a medical image capturing information processing unit 20, ).

In the implant model making system 10, the stored medical imaging data are read to extract two-dimensional data according to a predetermined anatomical implant model and to generate three-dimensional model data from the extracted two-dimensional model data And an image information extracting unit 30 for generating three-dimensional model data through data processing.

In addition, in the method of manufacturing the implant model, the image information extracting unit 30 reads the stored medical imaging data, extracts two-dimensional data according to a predetermined anatomical implant model, and extracts three- An image information extracting step S30 for generating three-dimensional model data through data processing for generating model data is performed.

Hereinafter, the detailed configuration of the image information extracting unit 30 and the image information extracting step S30 will be described.

That is, the image information extracting unit 30 includes a two-dimensional image information extracting module 31 for reading stored medical image sensing data and extracting two-dimensional data according to a predetermined anatomical implant model.

In addition, in the image information extracting step S30, the 2D image information extracting module 31 reads the stored medical image capturing data and extracts 2D image data according to a predetermined anatomical implant model The extraction step S31 is performed.

In particular, in the two-dimensional image information extraction module 31 and the two-dimensional image information extraction step S31, extraction of two-dimensional data from medical imaging data is performed through Radon transformation.

The image information extracting unit 30 includes a three-dimensional image information extracting module (not shown) for generating three-dimensional model data through data processing for generating three-dimensional model data from the extracted two-dimensional model data 32).

In the image information extracting step S30, the three-dimensional image information extracting module 32 extracts the three-dimensional model data from the extracted two-dimensional model data through data processing for generating three- Dimensional image information extraction step (S32) for generating 3D model data.

In the three-dimensional image information extraction module 32 and the three-dimensional image information extraction step S32, the three-dimensional model data is extracted from the data of the two-dimensional model through inverse transformation of the Radon Transform .

Thus, the 3D modeling data for the medical image of the object for producing the implant model is calculated. Next, it is a process for producing an implant model using such data.

That is, a 3D image data generation unit 40 for generating three-dimensional implant image data for model building using the generated 3D model data in the implant model production system 10 is provided.

In addition, in the method of fabricating an implant model, a 3D image data generation step (S40) of generating 3D implant preparation image data for model production using the generated 3D model data by the 3D image data generation unit 40 ).

Thus, we can calculate the data that can be used to create a 3D model of an actual implant model.

And an implant model information processing unit 50 for transferring image data for three-dimensional implant manufacturing to the implant model making apparatus 200 in the implant model making system 10 so that the implant model is produced.

In addition, in the method of manufacturing the implant model, the implant model information processing unit 50 transmits the image data for three-dimensional implant preparation to the implant model making apparatus 200, thereby preparing the implant model making step S50 .

Accordingly, various devices commonly known in the art can be used for the implant model making apparatus 200.

This process can be summarized as follows.

① Comparison and selection of medical image data (CT): It is to select medical image capturing information such as CT by grasping characteristics and shortcomings of representative medical image data (X-ray, MRI, CT)

② - a. Medical Image Information Extraction (CT): Extraction of data from the mathematical and anatomical aspects of CT image data.

② - b. Data conversion processing: Based on the data extracted from the mathematical and anatomical aspects, the two-dimensional data is calculated by three-dimensional data processing.

③ Imaging of three-dimensional information: Creation of data that can create an implant model by imaging three-dimensional data through appropriate software.

④ 3D print applicability: It is to make an implant model by compatible 3D print.

Hereinafter, a more detailed embodiment will be described with reference to the accompanying drawings and tables.

① Comparison and selection of medical image data (CT)

As shown in Table 1, image data suitable for medical situations can be obtained from various medical imaging devices. Implant models are constructed using these medical imaging data.

②-a. Medical image information extraction

■ Radon conversion

라고 하면, 각 광선

에 대한 선 적분은,Speaking of f (x, y) = ω (x, y, z 0) for ω (x, y, z) to said object (human body) in a three-dimensional, and a fixed value of z z ₀ f (x, y ) Can obtain a single-layered section of an object. The sections can be aligned and stacked in order to obtain the volume data of the object. Ideally, the thickness of each section should be infinitely small, but not in a real scanner, and can be adjusted within a certain range. For a fixed z value z ₀ , consider the intercept f (x, y) and the parallel rays passing through the object. (Fig. 2), a ray perpendicular to the line inclined by &thetas; in the x-axis and at a distance t from the origin

Respectively,

For the line integrals,

Lt; / RTI >

방향의 선(line)이다. 고정된 θ값에 대해 P_θ(t)는 1차원의 신호이고,This is called a Radon transform (P _θ (t)) at f (x, y). Where s is

It is a line in the direction. For a fixed θ value, P _θ (t) is a one-dimensional signal,

를 매개변수로 나타내면 xcosθ+ysinθ=t이므로, dirac delta함수를 쓰면,Is a complete set of primary projections of f (x, y).

Is expressed as a parameter, xcosθ + ysinθ = t. Therefore, by using the dirac delta function,

. Our goal is to reconstruct f (x, y) at P _θ (t).

②-b. Data conversion processing

Radiation, such as X-rays, has a different attenuation depending on the type of tissue in the body as it passes through the body. CT scan uses this fact to reconstruct the tomographic image of the human body by visualizing the distribution of the attenuation coefficient when the X-ray passes through the human body.

Based on reconstruction of the original image from a series of projections of the image.

■ Inversion of Radon Transform

The inverse Radon transform in two dimensions,

to be. Using the principal value,

Assuming that there exists and is continuous,

.

Where Hε (1) is

이다).. Hε (l) serves as a high-pass filter (the Fourier transform

to be).

The above integral is used to obtain f (x, y)

To "(x, y) plane", which is called reconstruction using filterd back-projection. Thereby generating three-dimensional image data.

③ Image generation step of 3D information

From the raw data obtained above, the 3D image data is used to construct the image through the 3D imageable software.

④ Implant model making by 3D printing

Through CAD or other software, it is predicted that the application of the technology for model making is sufficiently possible through the 3D printer compatible with the imaged file.

As described above, according to the present invention, a 3D implant model can be produced through 2D RawDate.

In addition, a 3D modeling process for a 3D implant model is performed using medical imaging information such as a lesion photograph, thereby making it possible to produce a model of an implant such as a customized knee joint.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments. The technical idea of the present invention should not be construed as being limited.

10: Implant model making system 20: Medical image taking information processor
30: image information extracting unit 40: 3D image data generating unit
50: Implant model information processing unit 100: Medical imaging device
200: Implant model making device

Claims (8)

A data processing method for extracting two-dimensional data according to a predetermined anatomical implant model from medical imaging data captured by a medical imaging apparatus and generating three-dimensional model data from the extracted two-dimensional model data, And a 3D implant model is produced by generating image data for three-dimensional implant production using the generated 3D model data. In this case, a patient-customized implant model Production method.
A medical image photographing information processing step of receiving, receiving, processing, and storing the image information photographed by the medical image photographing apparatus in a storage unit;
Dimensional medical image data through data processing for extracting two-dimensional data according to a predetermined anatomical implant model by reading the stored medical imaging data and generating three-dimensional model data from the extracted two-dimensional model data, An image information extracting step of generating data;
A 3D image data generation step of generating image data for three-dimensional implant preparation for model building using the generated 3D model data; And
A step of preparing an implant model for transferring image data for 3D implant preparation to an implant modeling apparatus and preparing an implant model;
Wherein the method comprises the steps of: preparing a patient-customized implant model using a 3D imaging technique.
3. The method of claim 2,
The image information extracting step includes:
A two-dimensional image information extraction step of reading the stored medical image pickup data and extracting two-dimensional data according to a predetermined anatomical implant model; And
And a 3D image information extracting step of generating 3D model data through data processing for generating 3D model data from the extracted 2D model data. How to make Patient Customized Implant Model.
The method of claim 3,
In the two-dimensional image information extracting step, the two-dimensional data is extracted from the medical image photographing data by Radon transformation,
Wherein the 3D model image data is extracted from the 2D model data through inversion of Radon Transform in the 3D image information extraction step.
A data processing method for extracting two-dimensional data according to a predetermined anatomical implant model from medical imaging data captured by a medical imaging apparatus and generating three-dimensional model data from the extracted two-dimensional model data, Dimensional model data, and generates three-dimensional image data for implant preparation using the generated three-dimensional model data. The system for creating a patient-customized implant model using the 3D imaging technique.
A medical image photographing information processing unit for receiving, receiving, processing, and storing the image information photographed from the medical image photographing apparatus in a storage unit;
Dimensional medical image data through data processing for extracting two-dimensional data according to a predetermined anatomical implant model by reading the stored medical imaging data and generating three-dimensional model data from the extracted two-dimensional model data, An image information extracting unit for generating data;
A 3D image data generation unit for generating image data for three-dimensional implant preparation for model building using the generated 3D model data; And
An implant model information processing unit for transferring image data for three-dimensional implant fabrication to an implant model manufacturing apparatus to make an implant model;
The system for creating a patient-customized implant using a 3D imaging technique.
The method according to claim 6,
Wherein the image information extracting unit comprises:
A two-dimensional image information extraction module for reading stored medical image data and extracting two-dimensional data according to a predetermined anatomical implant model; And
And a three-dimensional image information extraction module for generating three-dimensional model data through data processing for generating three-dimensional model data from the extracted two-dimensional model data. Patient Customized Implant Modeling System.
8. The method of claim 7,
In the two-dimensional image information extraction module, extraction of two-dimensional data from medical imaging data is performed through Radon transformation,
Wherein the three-dimensional image information extraction module extracts the three-dimensional model data from the data of the two-dimensional model through inversion of the Radon Transform to generate a patient-customized implant model using the 3D imaging technique.

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