KR20140103933A - Petrolatum Composition - Google Patents

Abstract

From 10 to 60% by weight of waxes having an average number of carbon atoms per molecule of from 25 to 70 and wherein the branches have 5 to 50% by weight of branched paraffins selected from methyl and ethyl branches, and linear 10 to 60% by weight of paraffin; And, optionally, a low melting point wax. The petrolatum composition has a dropping melting point of 35 to 80 캜.

Description

Petrolatum Composition < RTI ID = 0.0 >

The present invention relates to petrolatum compositions.

Petroleum jelly is a soft, oily, semi-solid mixture of hydrocarbons obtained from high boiling hydrocarbons and hydrocarbons, usually liquid at room temperature. )to be. Depending on the purity, petrolatum ranges from impure black petrolatum in color to highly pure petrolatum, which is usually white in color.

Typical characteristics of petrolatum are soft unctuous mass and slight fluorescence in sunlight when melted. Petroleum jelly is substantially insoluble in water, soluble in methylene chloride or hexane, and substantially insoluble in alcohol and glycerol.

Petroleum jellies are widely used as pharmaceutical ointment bases, infant care, cosmetics, leather care, elastomers, and also as greases or lubricants. It has alications. Petroleum jelly products are used for human consumption and should therefore be of high purity. For example, the product should contain less than 1 ppm polycyclic aromatic hydrocarbons (carcinogens) and the petroleum jelly must pass acidity / alkalinity and sulphated ash tests do.

White petroleum jelly / petrolatum is a mixture of purified and fully or nearly decolorized semi-solid hydrocarbons (C _n H _{2n + 2} ) obtained from petroleum and high boiling point liquid hydrocarbons. It has a translucent appearance of white or almost white.

Petrolatum is typically produced by mixing petroleum-derived oil components with slack waxes. Jojoba is obtained during the de-waxing process of lubricant base-oils from crude oil. These petroleum-based petrolatums are described in US Pat. No. 2,828,248 and US Pat. No. US Pat. No. 179,196. Although the term "petrolatum" is derived from petroleum, which is a fossil fuel derived product, petrolatum also includes those in which the molecules of at least one component (or all of its components) are derived by chemical synthesis And forms derived from synthetic sources. Petrolatum may also contain natural ingredients such as vegetable waxes.

British Patent GB 955348 discloses a cable impregnant comprising a mixture of 10-30% Fischer-Tropsch wax, 35-45% petroleum and 35-45% liquid polypropylene . Japanese Patent Publication JP 2009-234991 describes the use of Fischer-Tropsch wax and liquid paraffin to provide stick cosmetics. However, the characteristics of the stick type cosmetics are very different from those of the petrolatum in that the stick type cosmetics are not the unctuous paste, whereas the petrolatum is the milky face. Instead, stick-type cosmetics are more solid and harder than petrolatum, since stick-type cosmetics require mold release properties.

The use of synthetic components in petrolatum has been proposed in U.S. Pat. Nos. US 7851663, US 3764 and JP 2009-234991. U.S. Pat. No. 7,856,663 discloses a process for grafting paraffins produced by long chain olefins and Fischer Tropsch synthesis to provide iso-paraffins having long chain branches that exhibit properties of petrolatum. .

Synthetic waxes, for example, waxes obtained from the Fischer-Tropsch process, do not contain significant amounts of aromatic and polynuclear aromatic components, which are beneficial to petrolatum. However, when synthetic ingredients are used in petrolatum formulations, the use of cows is still challenging to obtain the three-dimensional network structure of US Pat. No. US 7851663, US Pat. No. 3,764 and Japanese patent document definitions stability and petrolatum It remains a challenge. In particular, when the petrolatum composition comprises linear paraffins that are liquid at room temperature, the linear paraffins tend to separate from the heavier components in the formulation, resulting in unstable petrolatum formulations. In order to obtain a stable composition, a "solvent binding" effect is required.

It is an object of the present invention to provide a stable petrolatum which normally contains liquid linear paraffin.

According to a first aspect of the present invention,

From 10 to 60% by weight of a wax having an average carbon number per molecule of from 25 to 70 and from 5 to 50% by weight of branched paraffins wherein the branches are selected from methyl and ethyl branches;

From 10 to 60% by weight of linear paraffins having an average carbon number per molecule of from 10 to 20; And

Optionally, a low melting wax;

/ RTI >

A petrolatum composition is provided having a drop melt point of 35 to 80 占 폚.

The wax (hereinafter, also referred to as a "wax component") may be an aliphatic wax. More specifically, it may be a hydrocarbon wax, preferably a paraffin wax. The wax may be a synthetic wax. Preferably, the wax is macrocrystalline synthetic wax. The wax may be present in an amount of 20 to 40% by weight or 25 to 35% by weight of the petrolatum composition. The wax may have an average carbon number of from 28 to 60 per molecule.

The wax may have branched paraffins of from 10 to 50% by weight, preferably from 20 to 40% by weight. In one embodiment of the present invention, the wax has less than 25% by weight branched paraffin. Preferably, the wax has a dropping melting point of 60 to 110 캜. The wax may have a carbon number per molecule of 25 to 70, preferably 28 to 60.

The wax may be selected from the group consisting of hydroisomerised wax, hydroisomerized Fischer-Tropsch wax, alpha-olefin wax and Fischer-Tropsch wax .

The linear paraffin (hereinafter also referred to as the 'linear paraffin component') may be synthetic paraffin, which may be a Fischer-Tropsch derived paraffin. The linear paraffin may be 20 to 40 wt% or 25 to 35 wt% of the petrolatum composition. Preferably, the linear paraffin has a melting point of 25 占 폚 or lower. The linear paraffin may have from 10 to 20 carbon atoms per molecule.

As used herein, the term " linear paraffin "refers to a straight-chain carbon backbone having no branches thereon (n-paraffin) and containing only carbon and hydrogen atoms, ≪ / RTI > Although the source of the linear paraffin used to prepare the petrolatum composition may include some branching molecules as shown in Table 1 below under the heading "linear paraffin ", these branching molecules are used for the present invention It is not a material.

The composition may also comprise a low melting wax (hereinafter also referred to as a "the low melt wax component"). When the low melting point wax is present, it may be a wax having a falling melting point of 20 to 30 캜. Preferably, the low melting wax has an average carbon number per molecule of 20 to 30. The low melting point wax may have a carbon number of 20 to 30 per molecule. The petrolatum composition may comprise from 10 to 60% by weight of the low melting point wax.

The low melting point wax may have branched paraffins of 15 to 30 wt%, preferably 20 to 28 wt%. The low melting point wax may be a hydrocarbon wax and preferably it is a paraffin wax. The low melting point wax may be a synthetic wax and is preferably a Fisher-Tropsch wax. The low melting point wax may be 20 to 40 wt% or even 25 to 35 wt% of the petrolatum composition.

The petrolatum composition may have a dropping melting point of 35 to 70 캜. Preferably, the petrolatum has a cone penetration of 60-300 mm / 10 (as measured by ASTM D937-07 using the cone defined in ASTM D217-10).

The petrolatum may be a white unctuous paste that is slightly fluorescent in the sunlight when melted.

In another preferred embodiment, there is provided a petrolatum composition as described in the present application, wherein each of said wax component and said linear paraffin component is synthesized. In another preferred embodiment, the wax component, the linear paraffin component and the low melting point wax component, respectively, are synthetic ingredients.

The Applicant has surprisingly found that stable petrolatum can be obtained with the compositions described in the present application.

According to a second aspect of the present invention there is provided the use of the petrolatum composition according to the first aspect of the present invention in a cosmetic, pharmaceutical or cable filling application, / RTI > Due to the absence of aromatics, sulfur and other skin irritants, the petrolatum is particularly suitable for use in skin care applications.

According to a third aspect of the present invention there is provided a method of manufacturing a cosmetic product, a pharmaceutical product, a cable-filling product, or a filled cable product, Lt; RTI ID = 0.0 > Petrolaton < / RTI >

According to a fourth aspect of the present invention there is provided a cosmetic composition or material, a pharmaceutical composition or material, a cable-filling composition or material, Adding the petrolatum composition according to the first aspect to a cable component to thereby produce a cosmetic product, a medicament, a cable-filled product or a filled cable product, which comprises obtaining a cosmetic product, a medicament, a cable-filled product or a filled- Is provided.

According to a fifth aspect of the present invention,

So that the petrolatum composition has a sufficient amount of the wax and the linear paraffin so as to have 10 to 60 wt% of wax and 10 to 60 wt% of linear paraffin, and

Wherein the petrolatum composition has a dropping melting point of 35 to < RTI ID = 0.0 > 80 C <

A wax having an average number of carbon atoms per molecule of 25 to 70 and having branches of 5 to 50 weight percent branched paraffins selected from methyl and ethyl branches, a linear paraffin having an average carbon number per molecule of 10 to 20, Melting point wax, thereby obtaining the petrolatum composition;

There is provided a process for producing the petrolatum composition of the first aspect of the present invention.

The method may further comprise adding 10 to 60% by weight of a low melting wax having an average carbon number per molecule of 20 to 30.

According to a sixth aspect of the present invention there is provided a cosmetic composition comprising 10 to 40% by weight of the petrolatum composition of the first aspect of the present invention.

The invention will be described in more detail with reference to the following non-limiting embodiments and the accompanying drawings.
1 shows the viscosity of O / W emulsions evaluated as good (cream D) and less good (cream A, B and C) for Example 2, FIG.
Figure 2 shows the boundaries for the onset and maximum viscosity of the flow in the region of excellent primary skin feel for cream and lotion, for Example 2;

Example  One

Manufacture of petrolatum

The petrolatum composition / samples were prepared according to the following recipe: In each case, the wax component and the low melting point wax component were melted in an oven at 100 占 폚. The paraffin, which is liquid at room temperature, was also preheated at 100 < 0 > C in an oven. The molten waxes were transferred to a clean stainless steel beaker and placed on a measuring scale to weigh accurately the amount of wax required according to the petroleum jelly formula. The temperature of the waxes was raised to 80 DEG C, and the molten waxes and the liquid paraffin (also at 80 DEG C) were mixed. The solutions were stirred until the resulting mixture was observed to become clear, and then left to set for 5 hours.

The above ingredients used had the properties described in Table 1 below (description of petrolatum components). The viscosity was measured using ASTM method D445. Dropping melting point was measured using ASTM method D127.

ingredient Explanation Minute map
(Branching degree)
^*** basin
shape
(Branching type) fall
Melting point
(Drop Melting Poing) Average carbon number
^**** Viscosity unit Weight% (Mass%) - ℃ - Centipoise
(cP) Wax component Susol wax H1
(Sasolwax H1) Hard ^* FT wax
(hard ^* FT wax) 6 methyl 110 C41 8.0@13 ° C Sexy Wax HX35 Hydrogenation - isomerization hard ^* FT
Wax 20 methyl 108 C40 9.0@13 ° C Sasol Wax C80M Hard ^* FT
Wax 10 methyl 89 C38 6.0 ° C C30 + Alpha-olefin 19 methyl 70 C30 6.4 @ C24-C28
Alpha-olefin Alpha-olefin 10 methyl 52 C26 2.3@100 ° C Low melting point wax Solsol wax F5 Heavy ^* FT wax
(medium ^* FT wax) 12 methyl 50 C27 3.6 ° C Sasol wax wax A Semi-liquid ^* FT wax 13 methyl 28 C21 5.6 @ Linear paraffin Sasol wax C14-C20 paraffin Liquid paraffin 8 methyl - C17 2.9 @ Sugar wax
C9-C11 paraffin Liquid paraffin 8 methyl - C10 2.6@40 ° C Crude oil based feedstock Sexy Wax 7836 Micro wax 82 C> 1 73 C55 12.8 ° C Jojoba wax Heavy wax 39 C> 1 40 C28 3.7@100 ° C Mineral oil
(mineral oil) Liquid oil 29 ^** C> 1 print - C23 12.5 @

^* FT Fisher Tropsch

^** Also contains 63% ring components

^*** molecules with at least one branch on the carbon skeleton, in percent (by weight) of the total molecule,

^**** Average carbon number per molecule

Determination of branching type and degree of components

The branch morphology and degree of each of the above components of the petrolatum composition was determined by High-Temperature GC (HTGC) using a Varian CP-3800 GC. Hydrogen (H ₂ ) was used as a carrier gas. A Restek MXT-1 capillary column (100% crosslinked dimethyl-polysiloxane) was used (length: 15 m, inner diameter: 0.28 mm, phase thickness: 0.15 탆). The injection was performed with a programmable on-column injector and a flame ionization detector (FID) was used. Xylene was used as a solvent for the wax. Table 2 (gas chromatography method used for analysis of the wax samples) shows the conditions used in this method.

Injector
Initial temperature (℃): 40
Initial delay time (minutes): 0
Ramp Rate (° C / min): 70
Temperature (° C): 420
Latency (minutes): 49.57
Total hours (in minutes): 55
EFC flow program (electro-flow control (EFC) flow program)
Flow (ml / min): 3.5
Delay time (minutes): 55.0 column
Initial temperature (℃): 40
Initial delay in minutes: 5
Tilt speed (° C / min): 10
Final temperature (캜): 440
Final delay time in minutes: 10
Total hours (in minutes): 55 Detector (flame ionization detector)
N ₂ make-up flow (ml / min): 25
Hydrogen flow (H ₂ flow) (ml / min): 30
Air flow (ml / min): 300
Detector temperature (占 폚): 450

Petrogradum  The properties of the composition / samples

Formulations and characterization results are shown in Table 3 (petroleum jelly formulations and properties).

Raw material Sample
→ One
◇◇◇ 2 3 4 5 6 7 Sasol wax 7836 ◇ 30 - - - - - - Jojoba wax ◇ 20 - - - - - - Mineral oil ◇ 45 - - - - - - Wax component Susol wax H1 - - 20 - - - - Sexy Wax HX35 - 20 - 20 20 30 4 Sasol Wax C80M - 5 5 5 - - 6 C30 + - 5 5 5 10 - - C24-C28
Alpha-olefin - - - - - - 19 Low melting point wax Solsol wax F5 5 5 5 5 10 20 4 Sugar wax
Wax A - 35 35 35 30 20 35 Linear paraffin Solsol wax C14-C20
paraffin - 30 30 - 30 30 32 Solsol wax C9-C11
paraffin - - - 30 - - - Total crude oil origin
(◇) Content (%): 95 0 0 0 0 0 0 Total Synthetic Content (%): 5 100 100 100 100 100 100 ocean White, oil-based paste
◇◇ White, oil-based paste White, oil-based paste Non-petrolatum, hard, wax-like products White, oil-based paste White, oil-based paste White, oil-based paste White, oil-based paste Dropping melting point
(° C) 35-70 ◇◇ 60.4 69.8 72.5 65.5 65.1 63.5 69.5 Cone penetration
(0.1 mm) 60-300 ◇◇ 160 162 20 170 185 187 167

◇ ◇ European Pharma requirement (Eur. Pharm requirement)

◇◇◇ Comparison example

All the samples shown in Table 3 have passed the polycyclic aromatic hydrocarbons, identification, acidity / alkalinity and sulfuric acid ash test as described in the European Pharmacopoeia.

Example 2

In personal protection products Petrolatum  use

General test conditions

Rheology is a science of materials transformation and flow as a function of the shear rate and shear stress applied to the product. Rheological measurements for this example were performed using an Anton Paar rheometer (Anton Paar GmbH, Strasbourg, Austria). The Anton Pareometer is a strain-controlled rheometer capable of measuring dynamic or static shear stress measurements and the resulting torque values exerted by the sample corresponding to the imposed shear strain, to be. The dynamic / static stress strain is applied by a step-motor and the torque is measured by a force rebalance transducer (FRT).

The thermal and shear history, aging and composition of the jellies significantly influence the yield stress measurement, see T. K. Parkins, J.B. Turner, Starting Behavior of Gathering Lines and Pipelines Filled with Gelled Prudhoe Bay J. Pet. Technol. 23 (1971) 301-308. For all measurements performed in this example, a freshly prepared sample was used and the sample was allowed to rest for 40 minutes after loading to allow for material relaxation and temperature equilibration. It has been found that 40 minutes is enough to allow the samples to fully relax and thermally equilibrate. All measurements were repeated at least 3 times for each test and in all cases highly reproducible data were obtained within a coefficient of variation of +/- 5%.

In this example, all measurements were performed with a parallel-plate fixture with a radius of 25 mm and a gap size of 2.5 mm. The larger gap size between the two plates ensures a smaller gap error.

Measurements for primary skin tactile test

During this investigation, the onset of flow (T _F ) of the cream samples was determined from the maximum of the viscosity curve? _Max (FIG. 1).

Sensory assessment results were obtained from a panel of 15 different age groups, gender and ethnicity. The panel was asked to evaluate four samples and to grade a product with a good sensory rating to a value of 10 and a product with a bad sensory rating to a value of zero (see Table 4 (panel sensory evaluation and rheological measurement Results)). Samples were evaluated during the blind test and the samples received by the panel were labeled with creams A to D.

product Used in cream
In petroleum jelly
Fisher-Tropsch
Wax% Shear stress
(Flow initiation)
T _F (Pascal) Dynamic maximum viscosity
η _max
(Pascal second) Sensory evaluation ^* Cream A
Cream B
Cream C
Cream D 0
0
100 ^**
65 36
21
26
16 14700
6700
4680
3400 5
6
7
8

^* 10, very good ... 1, poor (poor)

^** Petrolatum composition of sample 2 in Table 3 above

Creams A through D are all based on the following compositions (Table 5 (tested cream formulation)).

ingredient % function water
Disodium ethylenediamine tetraacetic acid
Propylene glycol
glycerin
Lipowax R2 (Lipowax R2)
Lipomulse 165 (Lipomulse 165)
Mineral oil
Petrogradum
Microcare Phthalate Dimethyl (Microcare DMP)
Parfum 66.3
0.1
1.5
3.5
6
2.5
4
15
0.6
0.5 Vehicle
Chelating agent
Moisturizer
Moisturizer
Viscosity modifier / stabilizer
Emulsifying agent
palliative
Blocker / emollient
Preservative
air freshener

The cream formulations used contained 15% petroleum jelly or petrolatum (Table 5), and Fisher Tropsch petroleum jelly products ranging from 0 to 100% were used to prepare the emulsions (Table 4). Cream A contains 0% Fisher-Tropsch wax and is a traditional mineral oil based jelly. Cream B also contains 100% mineral oil-based petroleum jelly, which has a slightly different formulation than the petroleum jelly used in Cream A. Cream C completely contains petroleum jelly based on Fisher-Tropsch wax; For cream D, synthetic petroleum jelly containing mostly 65% Fischer-Tropsch wax was used.

The sensory evaluation of the product's spreadability by the panel is related to the maximum viscosity and shear stress measured at the start of the flow depicted in the window as shown in Fig. The boundaries of the window were determined by the results of the cream samples to obtain good sensory evaluation results by a panel of people as shown in Fig. The graphical window of the diagram is depicted as measured values for shear stress and maximum viscosity at the start of flow and provides upper and lower limits for products with good sensory evaluation. Figure 2 shows the case where products according to the features of the present invention are measured in relation to rheological properties as compared to literature data of creams having good skin tenderness evaluation.

As shown in FIG. 2, only the cream D (including 65% Fischer-Tropsch wax) tested during this irradiation was used in cosmetic emulsions in Colloids and Surfaces, Physicochemical and Engineering Aspects 152 (1999) In a rheological study that objectifies the sensations that occur when applying to the skin, R. Brummer, S. & Belonging to the above window of good primary skin tactile as found by S. Gorderskty. During this investigation, it was found that formulations containing petroleum jelly based on 65% Fischer-Tropsch wax raw materials have the best primary sensory evaluation or spreadability as compared to traditional mineral oil based products. Commentary from the panel on cream D states that cream D had a smooth application and was easily absorbed. 100% Fischer-Tropsch based petroleum jelly cream C was just outside the boundary for good sensory evaluation. Cream C is closer to the window than mineral oil based products, Cream A and B. Cream C also received a higher rating by the panel. (2) the farther away the product is from the window defined for good sensory evaluation; It is interesting to note that the rating given by the panel is lower. Cream A was furthest away from the window and also received the lowest rating by the panel.

Claims (17)

From 10 to 60% by weight of a wax having an average carbon number per molecule of from 25 to 70 and from 5 to 50% by weight of branched paraffins wherein the branches are selected from methyl and ethyl branches;
From 10 to 60% by weight of linear paraffins having an average carbon number per molecule of from 10 to 20; And
Optionally, a low melting wax is included,
RTI ID = 0.0 > 80 C < / RTI > The method according to claim 1,
Wherein the wax is a synthetic wax. 3. The method according to claim 1 or 2,
Wherein the wax is 20 to 40% by weight of the petrolatum composition. The method according to claim 1,
Wherein the wax is selected from the group consisting of hydrogenated isomerized waxes, hydrogenated isomerized Fischer-Tropsch waxes, alpha-olefin waxes, and Fischer-Tropsch waxes. 5. The method according to any one of claims 1 to 4,
Wherein the linear paraffin is a Fischer-Tropsch derived paraffin. 6. The method according to any one of claims 1 to 5,
Wherein the linear paraffin comprises 20 to 40% by weight of the petrolatum composition. 7. The method according to any one of claims 1 to 6,
Wherein the low melting point wax has an average number of carbon atoms per molecule of from 20 to 30. 8. The method of claim 7,
Wherein the low melting point wax is a Fischer-Tropsch wax. 9. The method according to any one of claims 1 to 8,
RTI ID = 0.0 > 35-70 C. < / RTI > 10. The method according to any one of claims 1 to 9,
A petrolatum composition having a cone penetration of 60 to 300 mm / 10 (as measured by ASTM D937-07 using the cone defined in ASTM D217-10). The method according to claim 1,
Wherein the wax component and the linear paraffin components are each synthetic. 12. The method of claim 11,
Wherein the low melting point wax is present, and the synthetic wax is a petrolatum composition. Use of a petrolatum composition according to any one of claims 1 to 12 for cosmetic, pharmaceutical or cable filling. Use of a petrolatum composition according to any one of claims 1 to 12 in the manufacture of cosmetics, medicaments, cable-filled products or filled cable products. To a cosmetic composition or material, to a pharmaceutical composition or material, to a cable-filled composition or material, or to a cable or cable component, with a petrolatum composition according to any one of claims 1 to 12, A method of manufacturing a cosmetic, pharmaceutical, cable-filled or filled cable product, comprising obtaining a cable-filled product or a packed cable product. So that the petrolatum composition has a sufficient amount of the wax and the linear paraffin so as to have 10 to 60 wt% of wax and 10 to 60 wt% of linear paraffin, and
Wherein the petrolatum composition has a dropping melting point of 35 to < RTI ID = 0.0 > 80 C <
A wax having an average number of carbon atoms per molecule of 25 to 70 and having branches of 5 to 50 weight percent branched paraffins selected from methyl and ethyl branches, a linear paraffin having an average carbon number per molecule of 10 to 20, Melting point wax, thereby obtaining the petrolatum composition;
Lt; RTI ID = 0.0 > 1, < / RTI > 10. A cosmetic composition comprising the petrolatum composition of claim 1 in an amount of from 10 to 40% by weight.

Images