KR20090085237A - Herbal Medicine Composition for Prevention and Treatment of Brain Disease Containing Natural Pearl Powder - Google Patents
Herbal Medicine Composition for Prevention and Treatment of Brain Disease Containing Natural Pearl Powder Download PDFInfo
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- KR20090085237A KR20090085237A KR1020080011032A KR20080011032A KR20090085237A KR 20090085237 A KR20090085237 A KR 20090085237A KR 1020080011032 A KR1020080011032 A KR 1020080011032A KR 20080011032 A KR20080011032 A KR 20080011032A KR 20090085237 A KR20090085237 A KR 20090085237A
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Abstract
본 발명은 조성비로 황금, 당귀, 단삼, 백지, 오미자, 진교, 맥문동, 오수유, 대황(탄), 목향, 용뇌, 천연진주분을 함유하는 뇌질환(중풍, 치매) 예방 및 치료 등 한약 조성물에 관한 것이며, 본 발명의 조성물은 뇌혈관질환 예방과 치료에 우수한 효능을 가진다.The present invention in the composition of the Chinese herbal composition, such as golden, Angelica, Dansam, white paper, Schisandra chinensis, Jingyo, Magmun-dong, sorghum, rhubarb (tan), Mokyang, Longeruk, brain disease containing natural pearl powder (Mungpoong, dementia) The composition of the present invention has excellent efficacy in preventing and treating cerebrovascular diseases.
Description
본 발명은 천연 진주가루를 함유하는 뇌질환질환(ex. 중풍, 치매) 예방과 치료용 한약조성물에 관한 것으로, 보다 상세하게는 인류의 장수화로 노년인구증가와 음식문화, 스트레스 등으로 인하여 뇌혈관질환이 증가되는 것을 예방 및 치료를 위한 것으로 뇌동맥과 정맥의 혈전을 막아주고 심장을 안정시켜서 뇌기능 활성화용 한약 조성물에 관한 것이다.The present invention relates to a herbal composition for preventing and treating cerebral disease (ex. Para stroke, dementia) containing natural pearl powder, and more specifically, cerebral blood vessels due to an increase in elderly population, food culture, stress, etc. The present invention relates to a herbal composition for activating brain function by preventing blood clots in cerebral arteries and veins and stabilizing the heart by preventing diseases from increasing.
본 발명은 중국국가 기밀보호처방으로 등재되었던 화타재조환을 쓰던 중 열성반응이 많은 것에 착안하여 오수유의 함량을 줄이고 황금, 목향, 대황(탄), 천연진주분을 첨가하고 홍삼 대신 단삼을 첨가하여 사용하게 되었는데 그 치료효과가 훨씬 더 우수하였다.The present invention focuses on a lot of thermal reactions during the use of fire reconstruction, which was listed as a Chinese country's confidential prescription, reducing the amount of sewage oil, adding golden, mokyang, rhubarb (tan), natural pearl powder, and adding red ginseng instead of red ginseng. The effect was much better.
인체에 필요한 20여종의 아미노산과 28종의 미량원소가 들어있고 특히 열을 내리고 독을 풀어주며 눈을 밝게 하고 정신을 맑아지게 하며, 심신을 안정시키고 양생하는 작용이 있는 천연 진주가루를 신경보호작용이 있는 약물, 혈관을 열어주 는 약물 등과 배합하여 뇌혈관질환(중풍, 치매)을 우수하게 예방 및 치료하는데 우수한 효과를 나타냄을 발견하고 본 발명을 완성하게 되었다.It contains 20 kinds of amino acids and 28 kinds of trace elements which are needed for human body. Especially, it protects natural pearl powder that lowers heat, releases poisons, brightens eyes and clears the mind, stabilizes and cures the mind and body. In combination with drugs, drugs that open blood vessels, etc. have been found to exhibit excellent effects in excellent prevention and treatment of cerebrovascular diseases (Stroke, dementia) and completed the present invention.
본 발명의 목적은 뇌혈관질환을 예방 및 치료할 수 있는 한약조성물을 제공하는 것이다.An object of the present invention to provide a herbal composition that can prevent and treat cerebrovascular diseases.
상기 목적을 달성하기 위하여 본 발명은, 뇌질환 예방 및 치료용 한약조성물에 있어서, 황금 11 내지 13 중량부, 천궁 11 내지 13 중량부, 당귀 11 내지 13 중량부, 진교 11 내지 13 중량부, 단삼 11 내지 13 중량부, 백지 11 내지 13 중량부, 오미자 11 내지 13 중량부, 맥문동 7 내지 9 중량부, 오수유 3 내지 5 중량부, 대황(탄) 3 내지 5 중량부, 목향 2 내지 4 중량부, 용뇌 0.2 내지 0.4 중량부, 박하뇌 0.3 내지 0.5 중량부, 진주분 1 내지 2 중량부를 포함하여 이루어지는 것을 특징으로 하는 뇌혈관질환 예방 및 치료용 한약조성물을 제공한다.In order to achieve the above object, the present invention, in the herbal composition for the prevention and treatment of brain diseases, 11 to 13 parts by weight of gold, 11 to 13 parts by weight, Angelica 11 to 13 parts by weight, 11 to 13 parts by weight of Jinkyo, Dansam 11 to 13 parts by weight, 11 to 13 parts by weight of white paper, 11 to 13 parts by weight of Schizandra chinensis, 7 to 9 parts by weight of Macmundong, 3 to 5 parts by weight of sewage oil, 3 to 5 parts by weight of rhubarb (tan), 2 to 4 parts by weight of wood It provides a herbal composition for preventing and treating cerebrovascular diseases, comprising 0.2 to 0.4 parts by weight of brain, 0.3 to 0.5 parts by weight of peppermint, and 1 to 2 parts by weight of pearl powder.
또한, 상기 목적을 달성하기 위하여 본 발명은 상기 한약조성물을 포함하는 것을 특징으로 하는 뇌혈관질환 예방 및 치료용 한약 환제를 제공한다.In addition, the present invention provides a herbal medicine pill for preventing and treating cerebrovascular disease, characterized in that it comprises the herbal composition.
또한, 상기 목적을 달성하기 위하여 본 발명은 상기 한약조성물을 열수 추출하여 제조되는 열수추출물을 유효성분으로 포함하는 뇌혈관질환 예방 및 치료용 한약조성물을 제공한다.In addition, the present invention provides a herbal composition for the prevention and treatment of cerebrovascular disease comprising a hydrothermal extract prepared by extracting the herbal composition as hot water to achieve the above object.
본 발명에 의하면 본 발명의 한약조성물을 환제, 정제, 캡슐제, 액제, 건강식품, 건강음료 등과 같은 제형으로 복용함으로써 뇌질환(중풍, 치매)예방과 치료 에 우수한 효과를 발휘한다.According to the present invention by taking the herbal composition of the present invention in the form of pills, tablets, capsules, liquids, health foods, health drinks, etc., it has an excellent effect on the prevention and treatment of brain diseases (palsy, dementia).
본 발명에 따른 뇌질환(중풍, 치매) 예방 및 치료용 한약조성물의 구성성분을 설명한다.It describes the components of the herbal composition for the prevention and treatment of brain diseases (palsy, dementia) according to the present invention.
황금(黃芩, Scutellaria baicalensis)은 뿌리에 flavone glucuronide 화합물인 baicalin, baicalein, wogonin 등이 함유되어 있으며 성질이 찬 약으로 이뇨 지혈작용이 있으며, 폐의 열로 인한 해수(咳嗽), 황달, 하혈, 태동불안 등에 쓴다.Gold (Scutellaria baicalensis) contains flavone glucuronide compounds baicalin, baicalein, wogonin, etc. in the root and is a cold natured diuretic hemostatic effect, sea water, jaundice, bleeding, taedonganxiety due to lung heat Write on your back.
천궁(川芎, Cnidium officinale)은 피라진 이라는 성분이 주성분으로, 독특한 강한 향기 성분이 혈전(血栓)을 용해하여 혈액순환을 개선시키며, 진정·진통·강장에 효능이 있어 두통·빈혈증·부인병 등에 사용한다. 임상적으로 진경, 진정, 협압강화, 혈관확장, 항균작용 등의 치료에 쓰이고 있다.Cnidium officinale is the main ingredient of pyrazine, and its unique strong fragrance component dissolves blood clots to improve blood circulation. It is effective in calming, analgesic, and tonic. It is used for headache, anemia and women's diseases. . Clinically, it is used for the treatment of dyspnea, soothing, narrowing pressure, vasodilation, and antibacterial action.
당귀(當歸, Angelica gigas Nakai, 참당귀)의 주성분은 베투가프텐과 휘발성의 당귀유로서, 한국산 참당귀는 중국산 당귀보다 보혈작용보다는 피를 원활히 순환하게 해주는 활혈작용(活血作用)이 더 뛰어나며, 항암효과 및 혈압강하작용이 강하다. 약리학적으로 당귀는 관상동맥의 혈류량을 촉진시키고, 적혈구 생성을 왕성하게 한다.The main ingredient of Angelica gigas Nakai (beetle Angelica) is betugaphthene and volatile sugar donkey oil. Korean Angelica gigas has better blood circulation than Chinese donkey, which is more active in blood circulation. Anticancer effect and blood pressure lowering effect is strong. Pharmacologically, Angelica stimulates coronary blood flow and stimulates red blood cell production.
진교(, Gentiana macrophylla Pallas)는 리카코니틴, 미오스티닌 등을 함유하며, 풍습성 관절동통, 열이 나고 붓는 증상, 수족마비감, 황달, 뼛골이 쑤시고 조열이 나는 증상 등에 쓰인다. 약리작용은 항염증작용과 피부진균, 이질균 등에 대한 억균 작용이 보고되었다.School Gentiana macrophylla Pallas contains lycaconitine and myostinin, and it is used for customary joint pain, fever and swelling, hand and hand paralysis, jaundice, swelling and fever. Pharmacological action has been reported to anti-inflammatory action and fungal action against skin fungi, dysentery.
단삼(丹蔘, Salvia miltiorrhiza Bunge)은 심(心)에 들어가기 때문에 적삼(赤參)이라고 부르기도 한다. 스쿠텔라린(scutellarin)이 주성분으로, 혈액순환을 돕고, 어혈을 제거하며 사지관절 동통을 완화시킨다. 부인의 생리불순, 생리통, 산후복통, 어혈성심복부통, 타박상 등을 치료한다. 고열로 인한 정신혼몽, 헛소리, 번조, 불면증, 피부발진, 심계항진 등을 치료한다.Salvia miltiorrhiza Bunge is called red ginseng because it enters the heart. Scutellarin is the main ingredient, helping to circulate blood, remove blood and relieve joint pain. Menstrual dysmenorrhea, menstrual pain, postpartum abdominal pain, bloody heartache, bruises, etc. are treated. Heals mental fever, bullshit, annoyance, insomnia, skin rash, palpitations due to high fever.
약리작용은 관상동맥 확장, 콜레스테롤 강하, 혈압 강하, 간기능 활성화, 진정 항염, 항암, 항균작용이 보고되었다.Pharmacological action has been reported to coronary dilatation, lower cholesterol, lower blood pressure, activate liver function, sedative anti-inflammatory, anticancer, antibacterial activity.
백지(白芷, Angelica dahurica Bentham et Hooker)는 유행성 감기로 인한 두통, 코막힘, 콧물을 다스리는 진통약이며, 위장장애, 산전 산후두통, 어지럼증, 치통, 안면신경통, 마비 등에 유효하다. 또한 월경 뒤 하혈이나, 대하, 대변에 피가 섞여 나올 때, 축농증으로 인한 두통, 창양, 종독, 피부궤양 등에도 효과가 있다. 약리작용으로 항균 작용, 동물의 연수 혈관 운동 중추, 호흡중추, 미주 신경 및 척수부의 흥분 작용, 관상동맥 혈류량 증가작용, 백전풍(: 살갗에 흰 반점이 생기는 병증), 은설병(銀屑病: 만성피부병으로, 홍반과 구진으로 인하여 피부 표면에 여러 층으로 된 백색 비늘가루가 생기는 병증)에 유효작용이 보고되었다.White paper (白芷, Angelica dahurica Bentham et Hooker) is a pain medication for headaches, stuffy nose and runny nose caused by the flu, and is effective for gastrointestinal disorders, prenatal postpartum headache, dizziness, toothache, facial neuralgia, and numbness. In addition, when menstrual blood, stool, feces, feces after the menstruation, sinusitis caused by headaches, spear, swollen poison, skin ulcers are effective. Pharmacological action, antibacterial action, animal soft vascular movement center, respiratory center, excitatory effect of vagus nerve and spinal cord, coronary blood flow increase, baekjeon wind ( : It has been reported to be effective in white spots on skin), septic disease (銀屑病: chronic skin disease, multi-layered white scales on the surface of skin due to erythema and papules).
오미자(五味子, Schisandra chinensis Baillon)은 시잔드린·고미신·시트럴·사과산·시트르산 등의 성분이 들어 있어 심장을 강하게 하고 혈압을 내리며 면역력을 높여 주어 강장제로 쓴다. 약리작용으로 대뇌피질 흥분작용, 혈압 강하작용, 거담, 진해 작용, 호흡 흥분 작용, 강심작용, 당 대사 촉진과 당분해작용, 세포 면역 기능 증강작용, 자궁 흥분 작용, 담즙 분비 촉진 작용, 위액 분비 조절 작용, 억균작용이 보고되었다.Schisandra chinensis Baillon (Schisandra chinensis Baillon) contains ingredients such as cizandrin, gomisin, citric acid, citric acid, citric acid, etc. It is used as a tonic by strengthening the heart, lowering blood pressure and enhancing immunity. Pharmacological action: cerebral cortical excitability, blood pressure lowering, expectoration, antitussive action, respiratory excitability, cardiac action, glucose metabolism and glycolysis, cellular immune function enhancement, uterine excitability, bile secretion, gastric secretion control Actions, fungi have been reported.
맥문동(麥門冬, Liriope platyphylla Wang et Tang)은 진액을 보하는 대표적인 약으로 폐음손상으로 인한 마른기침, 각혈, 가래, 해수에 쓰며, 위음 부족으로 인한 갈증, 소갈 및 변비에도 사용한다. 음혈 소상으로 가슴답답하고 팔다리를 가만히 두지 못하는 증상과 불면증에 사용한다. 약리효과는 항산화작용, 혈류량촉진, 심장수축력증가, 진정, 면역증강, 혈당강하, 항균작용 등이 보고되었다.Limonpe platyphylla Wang et Tang (麥 門冬, Liriope platyphylla Wang et Tang) is a representative of the essence of the essence of the fluid used in dry cough, bleeding, sputum, sea water due to lung ulcer damage, thirst, dehydration and constipation due to lack of false negatives. It is used for insomnia and symptom of heart swelling and inability to keep limbs still. The pharmacological effects of antioxidant, blood flow promotion, cardiac contractility increase, sedation, immunity enhancement, hypoglycemic activity and antimicrobial activity have been reported.
오수유(吳茱萸, Evodia officinalis)의 주요 성분은 Evodiamine, Rutaecarpine, Evodene, Ocimene, Zimonin, Evodol 등으로 인체의 몸통부위를 따뜻하게 하며 통증을 완화시키고 기를 소통시키며 습을 말리는 효능이 있다. 주로 간 과 위가 차가워서 그 탁한 기운이 아래로 내려가지 못하고 위로 올라가서 생기는 두통, 찬 기운으로 인한 옆구리 통증 및 구토, 치통, 습진등을 치료한다.The main components of Osuyu (吳茱萸, Evodia officinalis) are Evodiamine, Rutaecarpine, Evodene, Ocimene, Zimonin, Evodol, etc. It has the effect of warming the torso area of the human body, relieving pain, communicating qi and drying moisture. The liver and stomach are cold, so the turbid energy does not go down, but the headache caused by going up, cold side, side pain, vomiting, toothache, eczema, etc. are treated.
대황탄(大黃炭, Rheum palmatum L.)은 사하작용으로 장위를 세척하고 대사를 촉진하며 열성변비와 복부창만을 치료한다. 화를 내려 두통, 충혈, 인후통, 변비, 이질 설사와 코피, 토혈, 종기, 허열에 효과가 있고 이뇨, 부종에도 사용한다. 약리작용으로 대장운동촉진, 사하작용, 해열, 체온강하, 담즙분비 촉진, 혈액응고 시간 단축, 항균, 이뇨, 간기능 보호 등이 보고되었다.Rheum palmatum (大黃 炭, Rheum palmatum L.) is a hypothalamic action to wash the stomach, promote metabolism, and treat only constipation and abdominal spear. Get angry, have headaches, hyperemia, sore throat, constipation, dysentery diarrhea and nosebleeds, bleeding, boils, fever, diuretic, edema is also used. Pharmacological action has been reported to promote colon exercise, lowering action, antipyretic, lowering body temperature, promoting bile secretion, shortening blood coagulation time, antibacterial, diuretic, protection of liver function.
목향(木香, Radix Saussurea Seu Inulae)은 복부가 차서 생기는 복통, 헛배 부른 증상, 구토, 설사에 사용하며 기를 잘 통하게 해 소화기의 만성 염증, 위통에 효과가 있고, 항균작용이 있어서 이질과 고환염에 쓴다. 약리작용으로 기관지와 소장 경련을 풀어 주며 혈압강하작용, 항균작용 등이 보고되었다.Mokhyang (木香, Radix Saussurea Seu Inulae) is used for abdominal pain caused by cold abdominal pain, flat stomach symptoms, vomiting and diarrhea, and it is effective for chronic inflammation of the digestive organs and stomach pain. Write Pharmacological action to release bronchial and small intestine spasms, blood pressure lowering action, antibacterial action has been reported.
용뇌(龍腦, Dryobalanops aromatica Gaertner)는 막힌 것을 통하게 하고 정신을 맑게 하여 정신혼몽, 의식장애 등을 열과 부기를 내리고 통증을 완화시켜 주며, 고열, 경련, 소아 경기에 효과가 있으며 인후염과 구내염, 눈병, 가려움증, 충혈, 귀코의 염증 등 각종 염증에 이용된다. 약리작용으로 항균, 항염증작용이 있으며, 국소적인 진통작용과 방부작용이 보고되었다.Dryobalanops aromatica Gaertner helps to block the blockage and clears the mind, reducing fever, swelling, and pain in mental disorders, consciousness disorders, etc. It is effective for fever, cramps, and pediatric competition. It is used for various inflammations such as itching, redness, and inflammation of the ear nose. Pharmacological action has antibacterial and anti-inflammatory effects, and local analgesic and antiseptic effects have been reported.
박하뇌(薄荷腦, Mentha arvensis var. piperascens)는 소염 진통작용이 뛰어나며, 상처부위의 염증을 치료하고 통증을 억제한다.Minty brain (薄荷 腦, Mentha arvensis var. Piperascens) is an anti-inflammatory analgesic, cures inflammation of the wound and suppresses pain.
진주분(珍珠紛, Ptreria margaritifera)은 진주의 미세분말로 여러 아미노산과 천연미네랄이 함유되어 있으며, 진주는 성질이 차고 무독(無毒)하여 심신을 평안케 하며 눈을 밝게 하고 피부의 종기를 다스리는 효과가 있으며, 필요없는 열을 내려주어, 급성 열병으로 인한 경풍이나 경계 정충을 다스린다.Pearl powder (Ptreria margaritifera) is a fine powder of pearl and contains various amino acids and natural minerals. Pearl is cold and non-toxic, so it helps to relax the mind and body, brighten the eyes and control the boils of the skin. It can lower unnecessary heat and control wind and border bugs caused by acute fever.
본 발명의 한약조성물은 이상의 성분들을 포함하되, 그 비율은 황금 11 내지 13 중량부, 천궁 11 내지 13 중량부, 당귀 11 내지 13 중량부, 진교 11 내지 13 중량부, 단삼 11 내지 13 중량부, 백지 11 내지 13 중량부, 오미자 11 내지 13 중량부, 맥문동 7 내지 9 중량부, 오수유 3 내지 5 중량부, 대황(탄) 3 내지 5 중량부, 목향 2 내지 4 중량부, 용뇌 0.2 내지 0.4 중량부, 박하뇌 0.3 내지 0.5 중량부, 진주분 1 내지 2 중량부를 포함하여 이루어진다.Chinese medicine composition of the present invention comprises the above components, the ratio is 11 to 13 parts by weight of gold, 11 to 13 parts by weight of cheongung, 11 to 13 parts by weight, Angelica 11 to 13 parts by weight, 11 to 13 parts by weight of Dansam, 11 to 13 parts by weight of white paper, 11 to 13 parts by weight of Schizandra chinensis, 7 to 9 parts by weight of Macmundong, 3 to 5 parts by weight of sewage oil, 3 to 5 parts by weight of rhubarb (coal), 2 to 4 parts by weight of cedar, 0.2 to 0.4 weight of cedar Part, the peppermint brain comprises 0.3 to 0.5 parts by weight, pearl powder 1 to 2 parts by weight.
이들 성분은 모두 한약제로서 사용되는 통상의 건조된 약재형태의 것을 의미한다. 상기 각 성분이 상, 하한치를 벗어날 경우 뇌질환(중풍, 치매)예방 및 치료 효과가 미약하거나 없게 된다.All of these components are meant to be in the form of conventional dried herbs used as herbal medicines. When each component is above the upper and lower limits, brain disease (stroke, dementia) prevention and treatment effect is weak or absent.
상기한 조성물을 갖는 본 발명의 한약조성물을 통상의 방법에 따라 열수추출하여 열수추출물을 얻을수 있으며, 이 추출물을 동결 건조하여 분말상 건조추출 물을 얻을 수도 있다. 열수추출은 섭씨 100~125도의 온도에서 2~3시간 동안 하는 것이 가장 바람직하다. The herbal composition of the present invention having the composition described above may be subjected to hot water extraction according to a conventional method to obtain a hot water extract, and the extract may be lyophilized to obtain a dry powder extract. Hot water extraction is most preferably performed for 2 to 3 hours at a temperature of 100-125 degrees Celsius.
또한, 상기 조성을 갖는 본 발명의 한약조성물은 분말하여 분말총량에 대하여 60%~70% 에 해당하는 찹쌀풀을 혼합하여 통상의 제환과정으로 제환하는 방법도 있다.In addition, the herbal composition of the present invention having the above composition may be powdered and mixed with glutinous rice paste corresponding to 60% to 70% based on the total amount of the powder to be recirculated in a normal recycling process.
또한, 상기 조성을 갖는 본 발명의 한약조성물을 통상의 방법에 따라 물, 탄소수 1내지5의 알코올 또는 알코올수용액으로 이루어지는 군으로부터 선택된 1종이상의 용매를 사용하여 추출함으로써 추출액을 얻을수 있으며, 이 추출액 또는 이를 동결건조하여 얻은 분말상 건조추출물을 뇌질환예방 및 치료에 사용할 수도 있다.In addition, the herbal composition of the present invention having the above composition can be extracted by using one or more solvents selected from the group consisting of water, alcohol having 1 to 5 carbon atoms or an aqueous solution of alcohol according to a conventional method, and the extract can be obtained or the same. Lyophilized powdered dry extracts may be used for the prevention and treatment of brain diseases.
이러한 본 발명의 한약조성물은 상기한 성분을 포함하여 제조된 것이라면 그 제형에 특별한 제한이 없으며, 예를 들어 환제, 정제, 캡슐제, 액제, 건강식품, 건강음료 등과 같은 제형을 가질 수 있다.Such a herbal composition of the present invention is not particularly limited as long as it is prepared by including the above components, and may have a formulation such as pills, tablets, capsules, liquids, health foods, health drinks, and the like.
이하, 제조에 및 실시예를 들어 본 발명을 상세히 설명하지만 본 발명이 이들 예로만 한정되는 것은 아니다.Hereinafter, the present invention will be described in detail by way of manufacture and examples, but the present invention is not limited only to these examples.
〈제조예 1〉한약 조성물<Production example 1> Chinese medicine composition
건조된 황금, 천궁, 당귀, 진교, 단삼, 백지, 오미자 각 60g, 맥문동 40g, 오수유 20g, 대황(탄) 20g, 목향 15g, 용뇌 1.5g, 박하뇌 2g, 진주분 5g을 균일하게 혼합 분해하여 찹쌀풀 320g과 같이 통상의 환 제조공정에 의하여 제환하여 멸균처리하여 제조하였다.Glutinous rice mixed with dried golden, Cheongung, Angelica, Jingyo, Dansam, white paper, Schisandra chinensis 60g, Macmundong 40g, Sewage oil 20g, Rhubarb (tan) 20g, Mokhyang 15g, Dragon head 1.5g, Mint brain 2g, Pearl powder 5g The paste was prepared by sterilization by recirculation according to a conventional ring manufacturing process such as 320 g of grass.
〈제조예 2〉한약조성물의 열수추출물<Manufacture example 2> Hot water extract of herbal composition
3차 증류수 10리터 가 담긴 플라스크에 제조예1의 혼합물 중 박하뇌, 용뇌, 진주분을 제외한 515g의 혼합물을 투입한 후 섭씨 100~120도의 온도에서 2시간 동안 열수 추출하여 열수 추출액에 박하뇌 2g, 용뇌 1.5g, 진주분 5g을 녹여서 120ml씩 포장하였다.Into the flask containing 10 liters of tertiary distilled water, 515 g of the mixture of peppermint brain, brain, and pearl powder was added to the flask of Preparation Example 1, followed by hot water extraction at a temperature of 100 to 120 degrees Celsius for 2 hours. 1.5 g and 5 g of pearl powder were dissolved and packed in 120 ml each.
〈시험예1〉중풍, 치매 전조증의 완화 효능평가<Test Example 1> Evaluation of palliative effect of stroke and dementia prognosis
2005년 10월부터 2007년 10월까지 출원인의 한의원에 방문한 중풍, 치매 전조증을 보인 45세 이상의 환자에게 30일간 1일2회 제조예2의 열수 추출액 120ml를 복용하도록 하였다.From October 2005 to October 2007, 120 years old patients with stroke and dementia prognosis who visited the Korean medical clinic of the applicant were asked to take 120 ml of hot water extract of Preparation Example 2 twice daily for 30 days.
복용 후 그 증상을 평가하도록 하고 그 결과를 표1에 나타내었다.After taking the drug, the symptoms were evaluated and the results are shown in Table 1.
[표 1]TABLE 1
치매전조증 32명32 dementia
중풍전조증 28명Psychiatric precursors 28 people
〈시험예 2〉<Test Example 2>
2005년 10월부터 2007년 10월까지 출원인의 한의원에 방문한 중풍, 치매에 걸린 45세 이상의 환자에게 60일간 1일 2회 제조예2의 열수추출액 120ml를 복용하도록 하였다. 복용 후 그 증상을 평가하도록 하고 그 결과를 표2에 나타내었다.From October 2005 to October 2007, 120 years of patients with stroke and dementia who visited the Korean medical clinic of the applicants were asked to take 120 ml of hot water extract of Preparation Example 2 twice daily for 60 days. After taking the drug, the symptoms were evaluated and the results are shown in Table 2.
[표 2]TABLE 2
치매환자 9명9 patients with dementia
중풍환자 13명13 stroke patients
상기에서 알 수 있는 바와 같이 본 발명의 한약조성물은 뇌질환(중풍, 치매)과 전조증에 대하여 완화와 치료 효능이 우수함을 확인할 수 있다.As can be seen from the above, the herbal composition of the present invention can be confirmed that the remission and treatment efficacy for brain diseases (Pung stroke, dementia) and prognostic symptoms are excellent.
이상에서 본 발명은 기재된 구체예에 대해서만 상세히 설명되었지만 본 발명의 기술사상 범위내에서 다양한 변형 및 수정이 가능함은 당업자들에게 있어서 명백할 것이며, 이러한 변형 및 수정이 첨부된 청구범위에 속함은 당연한 것이다.Although the present invention has been described in detail only with respect to the described embodiments, it will be apparent to those skilled in the art that various modifications and variations are possible within the technical spirit of the present invention, and such modifications and modifications belong to the appended claims. .
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014187942A1 (en) * | 2013-05-24 | 2014-11-27 | Nestec S.A. | Treatment or prevention of neurodegenerative disorders using menthol, linalool and/or icilin |
| WO2014187945A1 (en) * | 2013-05-24 | 2014-11-27 | Nestec S.A. | Treatment or prevention of non-inflammatory neuronal damage from brain trauma and strokes using menthol, linalool and/or icilin |
| CN104435551A (en) * | 2014-11-26 | 2015-03-25 | 张华� | Traditional Chinese medicine composition for treating hemiplegia |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014187942A1 (en) * | 2013-05-24 | 2014-11-27 | Nestec S.A. | Treatment or prevention of neurodegenerative disorders using menthol, linalool and/or icilin |
| WO2014187945A1 (en) * | 2013-05-24 | 2014-11-27 | Nestec S.A. | Treatment or prevention of non-inflammatory neuronal damage from brain trauma and strokes using menthol, linalool and/or icilin |
| CN105228601A (en) * | 2013-05-24 | 2016-01-06 | 雀巢产品技术援助有限公司 | Use menthol, linalool and/or ice extract for treating or prevention by cerebral trauma and in wind-induced non-inflammatory neuronal damage |
| JP2016524608A (en) * | 2013-05-24 | 2016-08-18 | ネステク ソシエテ アノニム | Treatment or prevention of neurodegenerative diseases using menthol, linalool and / or icilin |
| US10799502B2 (en) | 2013-05-24 | 2020-10-13 | Societe Des Produits Nestle S.A. | Treatment or prevention of non-inflammatory neuronal damage from brain trauma and strokes using Menthol, Linalool and/or Icilin |
| CN104435551A (en) * | 2014-11-26 | 2015-03-25 | 张华� | Traditional Chinese medicine composition for treating hemiplegia |
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