KR20090049897A - Tooth whitening composition containing cleansing capsule - Google Patents

Abstract

The present invention relates to a tooth whitening composition containing a cleansing capsule, and more particularly, to a tooth whitening composition containing a cleansing capsule containing a contaminant dissolving agent and a porous material as a whitening component in order to effectively remove tooth contamination. will be. The tooth whitening composition according to the present invention dissolves hydrophobic contaminants on the tooth surface by limonene collected in the cleansing capsule, and removes the dissolved contaminants by absorbing the porous contaminants, which is very effective in removing tooth contaminants. .

Cleansing, Capsules, Limonene, Porous Materials, Cleansing Capsules

Description

Tooth whitening composition containing cleansing capsule

The present invention relates to a tooth whitening composition containing a cleansing capsule, and more particularly, to a tooth whitening composition containing a cleansing capsule containing a contaminant dissolving agent and a porous material as a whitening component in order to effectively remove tooth contamination. will be. The tooth whitening composition according to the present invention dissolves hydrophobic contaminants on the tooth surface by limonene collected in the cleansing capsule, and removes the dissolved contaminants by absorbing the porous contaminants, which is very effective in removing tooth contaminants. .

Known tooth discoloration factors are endogenous tooth discoloration caused by nerve damage inside the tooth, aging or overdose of antibiotics such as tetracyclines, and food residues deposited on the tooth surface or nicotine and tar components of tobacco, coffee It can be divided into exogenous tooth discoloration caused by black tea.

Peroxides are used to treat endogenous tooth discoloration, and in order to treat exogenous tooth discoloration, abrasives are blended and physically removed or chemically removed using a surfactant.

In Korean Patent Laid-Open No. 2003-0044389, it is reported that limonene is included in addition to the surfactant in order to remove contaminants from the fiber, thereby showing excellent hydrophobic stain removal effect.

Although limonene is also used in the toothpaste composition, it was merely used as a kind of fragrance and was not used to remove contamination.

When a large amount of an oil component such as limonene is blended in the dentifrice composition, there is a problem of deterioration of bubble power during brushing. In Japanese Patent Laid-Open No. 10-067625, a lipophilic component such as limonene is mainly composed of gellan gum. There is mentioned a composition for oral cavity comprising a capsule collected into a coating. Since this invention only intended to keep the lipophilic component stable in the toothpaste formulation, there was no consideration for enhancing the cleansing effect.

Therefore, the present inventors have been studying a method for effectively removing the contamination caused by the exogenous pigmentation of the tooth, while preparing a cleansing capsule containing a contaminant dissolving agent and a porous material as a whitening component and applying it to the oral composition, Hydrophobic contaminants on the tooth surface were dissolved by the collected contaminant solubilizer, and the dissolved contaminants were adsorbed and removed from the porous material, thereby completing the present invention.

Accordingly, it is an object of the present invention to provide a composition for whitening teeth which effectively removes contamination by exogenous coloring of teeth.

In order to achieve the above object, the present invention provides a composition for whitening teeth comprising a cleansing capsule containing a contaminant dissolving agent and a porous material as a tooth whitening component.

The tooth whitening composition according to the present invention was very effective in dissolving hydrophobic contaminants on the tooth surface by the contaminant dissolving agent collected in the cleansing capsule, and the dissolved contaminants were adsorbed on the porous material to remove the contaminants.

Hereinafter, the present invention will be described in more detail.

The cleansing capsule according to the present invention includes a contaminant dissolving agent and a porous material as a whitening ingredient.

In the present invention, as a contaminant dissolving agent for chemically removing contaminants of teeth, extracts such as lemon or orange containing a large amount of limonene or limonene may be used.

The lemon or orange extract used in the present invention is dried and then added to 3 to 30L of 20 to 95% ethanol per kg of dried skin, extracted at 25 to 80 ° C. for 1 to 12 hours, and then the extract is filtered and the filtrate is vacuumed. It is prepared by concentration.

The content of the contaminant dissolving agent is preferably 0.1 to 30% by weight based on the total weight of the capsule, and when the content of the dissolving agent is less than 0.1% by weight, the dissolving power of the cleansing capsule is too low to have a substantial decontamination effect. If the weight percentage is exceeded, the strength of the capsule is so low that there is a problem that all capsules collapse during toothpaste preparation.

As the porous material used in the present invention, a porous material having a particle size of 5 to 600 µm, preferably 10 to 400 µm, in particular, a porous material having a primary particle size of 1 to 100 nm is used. Examples of such porous materials include inorganic powders such as silica, calcium carbonate, dibasic calcium phosphate, aluminum hydroxide and kaolin, as well as polyethylene, polyvinyl chloride, polyester, polystyrene, polypropylene, polyamide, polycarbonate, phenolic resin, Polymeric materials such as paper, polymethyl methacrylate resin and melamine resin can also be used.

The content of the porous material is preferably 5 to 70% by weight based on the total weight of the capsule, and when the content of the porous material is less than 5% by weight, there is a problem that the dissolved contaminants are not sufficiently adsorbed and removed, and 70% by weight. In the case of exceeding the content of the coating agent of the capsule outer wall is too low a problem that does not coat the capsule sufficiently.

In a preferred embodiment of the present invention, a cleansing capsule is prepared using porous silica and limonene.

Meanwhile, in the present invention, the contaminant dissolving agent and the porous material may be mixed with a water insoluble solvent such as beeswax to prepare a cleansing capsule by a conventional method well known in the art using a fluidized bed granulator or a dry sprayer. .

Looking at the manufacturing process of the cleansing capsule used in the present invention in more detail as follows:

1) preparing an emulsion solution by dispersing a lemon or orange extract (hereinafter referred to as "limonene") and a porous material containing a large amount of limonene or limonene in a water-insoluble solvent; And

2) preparing the emulsion solution into a spherical capsule using a spray dryer;

Characterized in that it comprises a.

As a dispersion medium for uniformly dispersing the limonene and the porous material as described above, a water-insoluble material that exhibits a solid phase at room temperature may be used. As such a water-insoluble substance, preferably wax or oil can be used, and more preferably at least one selected from the group consisting of carnauba wax, bis wax, paraffin wax, animal stearate, coconut oil, palm oil and the like. Can be selected and used.

Since the prepared cleansing capsule is used in the oral composition, if the hardness of the capsule itself is too strong, it may damage the oral mucosa during use, and a sense of foreign body may be felt strongly, and thus it is used for adjusting the hardness of the cleansing capsule. It may be used by mixing one or more of the water-insoluble substances.

Spray drier was used in the present invention to prepare an emulsion solution containing limonene and a porous material prepared as in step 1) of the above method into a capsule in the form of a sphere. In general, a spray dryer is a device used to evaporate a solvent and obtain a powder form product while spraying a solution in which a specific component is dissolved. However, the spray dryer used in the present invention utilizes the principle of cooling and drying while free-falling in the chamber of the spray dryer when the emulsion solution is injected, rather than evaporating the solvent to form a spherical shape. At this time, the temperature inside the chamber may be any temperature that can be cooled and dried, but preferably 10 to 20 ° C.

Cleansing capsule of the present invention prepared through the above process has an average particle size of 300 ~ 600㎛.

The present invention relates to a composition for whitening teeth containing the cleansing capsule, wherein the composition for teeth whitening according to the present invention preferably contains the cleansing capsule at 0.05 to 10% by weight based on the total weight of the composition, and the cleansing capsule If the content of less than 0.05% by weight, the problem that can not remove the contamination substantially occurs, if the content of more than 10% by weight of the capsule in the toothpaste formulation is too high, the appearance of the toothpaste is not good, and when brushing Foreign object occurs.

In addition, even when the cleansing capsule according to the present invention is applied to the composition for oral cavity containing hydrogen peroxide water, it is possible to prepare a formulation having excellent effect of removing external staining and excellent whitening effect.

Other compounding components of the tooth whitening composition used in the present invention can be easily selected and changed by those skilled in the art according to the use and type of the composition in addition to the cleansing capsules described above.

Various toothpaste compositions for carrying out the present invention should use appropriate ingredients according to the kind, for example, as a conventional toothpaste components, such as abrasives, wetting agents, foaming agents, binders, sweeteners, pH adjusting agents, preservatives, active ingredients, flavoring agents, brighteners, A dye, a solvent, etc. can be contained.

The abrasive used in the present invention includes, but is not limited to, calcium carbonate, precipitated silica, aluminum hydroxide, calcium dihydrogen phosphate, insoluble sodium metaphosphate, and the like. These abrasives may be used alone or in admixture of two or more, 1-60% by weight, preferably 10-50% by weight, based on the total weight of the composition.

Wetting agents used in the present invention include, but are not limited to, glycerin, sorbitol liquid, polyethylene glycol and propylene glycol. These humectants may be used alone or in admixture of two or more, 10-60% by weight, preferably 20-50% by weight, based on the total weight of the composition.

As the foaming agent used in the present invention, anionic and nonionic surfactants such as sodium lauryl sulfate, sodium lauryl sarcosinate, sucrose fatty acid ester, polyoxyethylene-cured castor oil and polyoxyethylene polyoxypropylene copolymer alone or 2 It can mix 0.5 or more, and can use 0.5-5 weight% with respect to the total weight of a composition, Preferably 0.5-3 weight% is used.

As the binder used in the present invention, sodium carboxymethyl cellulose, hydroxymethyl cellulose, carrageenan, xanthan gum and sodium alginate may be used alone or in combination of two or more thereof, and 0.1-5% by weight, preferably 0.1- 2% by weight can be used.

As the sweetener used in the present invention, 0.05-5% by weight of saccharin sodium, aspartame, stevioside, xylitol and licorice may be used alone or in combination of two or more kinds thereof.

As the pH adjusting agent used in the present invention, sodium phosphate, disodium phosphate, trisodium phosphate, sodium pyrophosphate, citric acid, sodium citrate and tartaric acid may be used. Preservatives include methyl paraoxybenzoate, propyl paraoxybenzoate and benzoic acid. Sodium may be used alone or in combination of two or more thereof.

The active ingredients used in the present invention include sodium fluoride, sodium monofluorophosphate, tin fluoride, chlorohexidine, allantoin chlorohydroxy aluminate, aminocaproic acid, tranexamic acid, trichloric acid, cetylpyrididium, zinc chloride , Pyridoxine hydrochloride, tocopherol acetate and the like can be used alone or in combination of two or more thereof.As a fragrance, peppermint oil, spearmint oil, menthol and anetol can be mixed in an appropriate amount. Furnace can be prepared in accordance with the conventional toothpaste manufacturing method in a solvent of purified water and purified water and ethanol.

Hereinafter, the composition and effect of the tooth whitening composition according to the present invention will be described in more detail with examples and formulation examples. However, the present invention is not limited only to these examples.

Example 1 Preparation of Cleansing Capsule

After drying the lemon peel, 10L of 95% ethanol was added per 1 kg of dried peel, extracted at 60 ° C. for 10 hours, and the extract was filtered and the filtrate was concentrated in vacuo to obtain a lemon extract.

80 g of beeswax was heated to 65-75 ° C., and 10 g of silica granules and 10 g of lemon extract were added thereto and stirred to keep the porous silica powder from sinking. 100 g of the spherical cleansing capsule was prepared by adding the prepared liquid mixture to a spray dryer and simultaneously cooling and drying the sprayer. Capsules used in the present invention have a particle size of 300-600 μm in perfect spherical form.

Example 2

It was prepared in the same manner as in Example 1 except that limonene was used instead of the lemon extract in Example 1.

[Formulation Examples 1 to 3 and Comparative Formulation Examples 1 to 4]

Toothpaste of Formulation Examples 1 to 3 and Comparative Formulation Examples 1 to 4 was prepared according to the method for preparing a toothpaste according to the formulation of Table 1 below.

ingredient Formulation Example 1 Formulation Example 2 Formulation Example 3 Comparative Formulation Example 1 Comparative Formulation Example 2 Comparative Formulation Example 3 Comparative Formulation Example 4 Function 17 17 17 17 17 17 17 Sodium fluoride 0.22 0.22 0.22 0.22 0.22 0.22 0.22 Sorbitol solution 50 50 50 50 50 50 50 Carboxymethyl Cellulose Sodium 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Sodium Lauryl Sulfate 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Methylparaben 0.15 0.15 0.15 0.15 0.15 0.15 0.15 Hydrogen peroxide (35%) - 2.15 - - - 2.15 - Porous silica powder - - - - 0.1 Limonene - - - - 0.1 - - Cleansing Capsule (Example 1) 1.0 1.0 - - - - Cleansing Capsule (Example 2) 1.0 - - - - Gellan gum capsules 1.0 Titanium dioxide 0.4 0.4 0.4 0.4 0.4 0.4 0.4 Zaccarin Sodium 0.2 0.2 0.2 0.2 0.2 0.2 0.2 Purified water Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount

In Formulation Examples 1 and 2, the cleansing capsules prepared in Example 1 were added, and in Formulation Example 3, the cleansing capsules prepared in Example 2 were added. In Comparative Example 2, limonene and porous silica granules were used instead of the cleansing capsules. In Example 4 gellan gum capsules were added. Gellan gum capsules added above were prepared according to the method described in Japanese Patent Laid-Open No. 10-067625.

[Test Example 1] Measurement of tooth whitening effect (in vivo)

In order to examine the tooth whitening effect of the toothpaste for tooth whitening according to the present invention, 150 healthy male and female experimenters were selected as samples and the tooth chromaticity before and after use was measured.

First, the original tooth tone of the test subject was measured using SHADEEYE-EX (SHOFU Co.LTD., Japan). Place the SHADEEYE-EX tip 2 mm above the maxillary left central incisal buccal cervical region and at a right angle so that light does not leak out to the tooth surface in the middle of the mesial, irradiating light and measuring the primary baseline data. Toothpaste was prepared three times a day with the toothpaste of Formulation Examples 1 to 3 and Comparative Formulations 1 to 4 prepared. During the test, he was allowed to eat food according to his or her usual diet, but coffee, cola, and cigarettes were prohibited before chromaticity was measured on the day of chromaticity measurement. Two months after using the toothpaste of Formulation Examples 1-3 and Comparative Formulation Examples 1-4, the chromaticity was measured (secondary measurement), and the results are shown in Tables 2 and 3, respectively.

Tooth chromaticity change measurement result after two months Baseline mean Average after 2 months Formulation Example 1 7.89 6.15 Formulation Example 2 7.87 5.14 Formulation Example 3 7.82 5.85 Comparative Formulation Example 1 7.70 7.62 Comparative Formulation Example 2 7.90 7.34 Comparative Formulation Example 3 7.75 5.95 Comparative Formulation Example 4 7.79 7.54

Teeth whitening effect measurement result after two months Improved same Worse Formulation Example 1 34 (68%) 16 (32%) 0 (0%) Formulation Example 2 41 (82%) 9 (18%) 0 (0%) Formulation Example 3 36 (72%) 14 (28%) 0 (0%) Comparative Formulation Example 1 2 (4%) 47 (94%) 1 (2%) Comparative Formulation Example 2 6 (12%) 44 (88%) 0 (0%) Comparative Formulation Example 3 36 (72%) 14 (28%) 0 (0%) Comparative Formulation Example 4 3 (6%) 47 (94%) 0 (0%)

From the results of Tables 2 and 3, the toothpaste of Formulation Example 1 and Formulation 3 was superior to the toothpaste removal effect compared to the toothpaste of Comparative Formulation Examples 1, 2, 4, it was confirmed that the whitening effect was excellent. In addition, in the toothpaste containing hydrogen peroxide solution, the toothpaste of Formulation Example 2 was found to have a superior whitening effect as compared to Comparative Formulation Example 3 with an excellent effect of removing external staining.

Test Example 2 Evaluation

1 g of toothpaste of Formulation Examples 1 and 2 and Comparative Formulation Examples 1 and 2 were applied to the toothbrush soaked with saliva, and then brushed with 30 subjects for 3 minutes, washed 5 times with water, and then scored 5 points of bubble power and bitterness. Measured after brushing on a scale, the results are shown in Table 4 below.

Formulation Example 1 Formulation Example 2 Comparative Formulation Example 1 Comparative Formulation Example 2 Bubble 3.9 3.9 4.1 2.7 bitter 2.1 2.2 1.9 3.9

As can be seen from the results of Table 4, the foaming power decrease and bitter taste increase in Comparative Formulation Example 2 to which limonene was added directly, Formulation Examples 1 to 2 including a cleansing capsule does not include a whitening component There was no significant difference in foaming power and bitter taste with Comparative Formulation Example 1.

Claims (9)

1) at least one selected from the group consisting of limonene, lemon extract and orange extract; And 2) porous material; Tooth whitening composition containing a capsule containing a. The method of claim 1, wherein the porous material is an inorganic powder comprising silica, calcium carbonate, dicalcium phosphate, aluminum hydroxide and kaolin; And a polymer material including polyethylene, polyvinyl chloride, polyester, polystyrene, polypropylene, polyamide, polycarbonate, phenol resin, urea resin, polymethyl methacrylate resin, and melamine resin. Tooth whitening composition. The composition of claim 1, wherein the capsule has a particle size of 300-600 μm. The composition of claim 1, wherein the capsule is prepared by further mixing a water-insoluble solvent. The composition of claim 4, wherein the water-insoluble solvent is at least one selected from the group consisting of carnauba wax, bis wax, paraffin wax, animal stearate, coconut oil, and palm oil. The composition for tooth whitening according to claim 1, wherein the composition further contains hydrogen peroxide water. 1) dispersing limonene, lemon extract or orange extract with a porous material in a water insoluble solvent to prepare an emulsion solution; And 2) preparing the emulsion solution into a spherical capsule using a spray dryer; Method for producing a composition for whitening teeth comprising a. The method of claim 7, wherein the porous material is inorganic powder including silica, calcium carbonate, dicalcium phosphate, aluminum hydroxide and kaolin; And a polymer material including polyethylene, polyvinyl chloride, polyester, polystyrene, polypropylene, polyamide, polycarbonate, phenol resin, urea resin, polymethyl methacrylate resin, and melamine resin. Method for producing a composition for whitening teeth. The method of claim 7, wherein the water-insoluble solvent is at least one selected from the group consisting of carnauba wax, bis wax, paraffin wax, animal stearate, coconut oil and palm oil. .