KR20080007371A - 비구아니드 화합물 함유 과립성 제제 - Google Patents

비구아니드 화합물 함유 과립성 제제 Download PDF

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Publication number: KR20080007371A
Authority: KR; South Korea
Prior art keywords: granular; granular preparation; preparation according; pullulan; metformin
Prior art date: 2005-04-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

KR1020077026775A

Other languages

English (en)

Korean (ko)

Inventor

야스시 오치아이

야스히로 마츠이

Original Assignee

다이닛본 스미토모 세이야꾸 가부시끼가이샤

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-04-26

Filing date

2006-04-26

Publication date

2008-01-18

2006-04-26 Application filed by 다이닛본 스미토모 세이야꾸 가부시끼가이샤 filed Critical 다이닛본 스미토모 세이야꾸 가부시끼가이샤

2008-01-18 Publication of KR20080007371A publication Critical patent/KR20080007371A/ko

Status Ceased legal-status Critical Current

Links

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239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
229940085605 saccharin sodium Drugs 0.000 description 1
235000002639 sodium chloride Nutrition 0.000 description 1
235000010356 sorbitol Nutrition 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
229960002920 sorbitol Drugs 0.000 description 1
238000013112 stability test Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
125000001424 substituent group Chemical group 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
238000009495 sugar coating Methods 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
238000012360 testing method Methods 0.000 description 1
150000004044 tetrasaccharides Chemical class 0.000 description 1
229920002554 vinyl polymer Polymers 0.000 description 1
229910009112 xH2O Inorganic materials 0.000 description 1
239000000811 xylitol Substances 0.000 description 1
235000010447 xylitol Nutrition 0.000 description 1
HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
229960002675 xylitol Drugs 0.000 description 1
FYGDTMLNYKFZSV-BYLHFPJWSA-N β-1,4-galactotrioside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@H](CO)O[C@@H](O[C@@H]2[C@@H](O[C@@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-BYLHFPJWSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Inorganic Chemistry (AREA)
Obesity (AREA)
Nutrition Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Physiology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Glanulating (AREA)
Manufacturing Of Micro-Capsules (AREA)

KR1020077026775A 2005-04-26 2006-04-26 비구아니드 화합물 함유 과립성 제제 Ceased KR20080007371A (ko)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JPJP-P-2005-00127360		2005-04-26
JP2005127360		2005-04-26

Publications (1)

Publication Number	Publication Date
KR20080007371A true KR20080007371A (ko)	2008-01-18

Family

ID=37307936

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1020077026775A Ceased KR20080007371A (ko)	2005-04-26	2006-04-26	비구아니드 화합물 함유 과립성 제제

Country Status (13)

Country	Link
US (1)	US8192761B2 (ja)
EP (2)	EP1878426B1 (ja)
JP (1)	JP5084499B2 (ja)
KR (1)	KR20080007371A (ja)
CN (1)	CN101198319B (ja)
CA (1)	CA2607419C (ja)
CY (1)	CY1110756T1 (ja)
DE (1)	DE602006014958D1 (ja)
ES (1)	ES2343432T3 (ja)
PL (1)	PL1878426T3 (ja)
PT (1)	PT1878426E (ja)
SI (1)	SI1878426T1 (ja)
WO (1)	WO2006118137A1 (ja)

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US20100093875A1 (en) *	2006-10-25	2010-04-15	Dainippon Sumitomo Pharma Co., Ltd.	Granular preparation prevented from caking
US20080107787A1 (en) *	2006-11-02	2008-05-08	The Coca-Cola Company	Anti-Diabetic Composition with High-Potency Sweetener
MX2011001487A (es) *	2008-08-08	2011-03-30	Mcneil Ppc Inc	Uso de sucralosa como agente granulante.
TW201138843A (en)	2009-12-18	2011-11-16	Colgate Palmolive Co	Biguanide preservation of precipitated calcium carbonate
WO2011154975A2 (en)	2010-06-08	2011-12-15	Cadila Healthcare Limited	Pharmaceutical compositions of metformin
EP2663294B1 (en)	2011-01-11	2015-09-30	Capsugel Belgium NV	New hard capsules comprising pullulan
US11576870B2 (en)	2017-04-14	2023-02-14	Capsugel Belgium Nv	Pullulan capsules
EP3610028A1 (en)	2017-04-14	2020-02-19	Capsugel Belgium NV	Process for making pullulan
US20200093646A1 (en) *	2018-09-20	2020-03-26	Kci Licensing, Inc.	Super-absorbent, low trauma, advanced wound dressing

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US5026560A (en) *	1987-01-29	1991-06-25	Takeda Chemical Industries, Ltd.	Spherical granules having core and their production
JP3583166B2 (ja)	1994-06-27	2004-10-27	興和株式会社	損傷皮膚修復用粉末製剤
DE4432757A1 (de)	1994-09-14	1996-03-21	Boehringer Mannheim Gmbh	Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
US6413541B1 (en) *	1999-01-13	2002-07-02	Dainippon Pharmaceutical Co., Ltd.	Disintegrating tablet in oral cavity and production thereof
EP1082109B1 (en)	1998-04-29	2004-06-16	Sumitomo Pharmaceuticals Company, Limited	Oral formulation comprising biguanide and an organic acid
JP4606582B2 (ja) *	1998-04-29	2011-01-05	大日本住友製薬株式会社	ビグアナイド系薬物の内服製剤
AR030920A1 (es)	1999-11-16	2003-09-03	Smithkline Beecham Plc	Composiciones farmaceuticas para el tratamiento de la diabetes mellitus y condiciones asociadas con la diabetes mellitus, y procedimientos para preparar dichas composiciones
NZ524519A (en) *	2000-08-07	2004-09-24	Ranbaxy Signature Llc	Liquid formulation of metformin
JP2002241267A (ja)	2000-12-11	2002-08-28	Takeda Chem Ind Ltd	水溶解性が改善された医薬組成物
EP1238662B1 (en) *	2001-03-07	2006-05-31	Dainippon Sumitomo Pharma Co., Ltd.	Method for manufacturing drug granules, the drug granules and pharmaceutical preparation containing the drug granules
JP4438268B2 (ja)	2001-03-07	2010-03-24	大日本住友製薬株式会社	薬物顆粒の製造方法、および薬物顆粒、ならびにそれを用いた医薬製剤
US20040202718A1 (en) *	2001-09-28	2004-10-14	Tyebji Ziauddin Z.	Dosage form for treatment of diabetes mellitus
AU2003241537A1 (en)	2002-05-23	2003-12-12	Andrx Corporation	Biguanide formulations
PA8576201A1 (es) *	2002-07-10	2004-05-26	Pfizer Prod Inc	Composicion farmaceutica que tiene una distribucion y potencia uniforme de farmaco
UA80991C2 (en)	2002-10-07	2007-11-26		Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
CN1805738A (zh) *	2003-06-16	2006-07-19	兰贝克赛实验室有限公司	持续释放的二甲双胍片剂
FR2858556B1 (fr)	2003-08-06	2006-03-10	Galenix Innovations	Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation
JP2005068116A (ja)	2003-08-28	2005-03-17	Toa Eiyo Ltd	塩酸メトホルミンを含有する速放性フィルムコーティング錠剤
JP2005139173A (ja)	2003-10-17	2005-06-02	Medorekkusu:Kk	ビグアナイド系薬剤を含有するゼリー製剤
WO2005037264A1 (ja) *	2003-10-17	2005-04-28	Medrx Co., Ltd.	ビグアナイド系薬剤を含有するゼリー製剤
JP4814636B2 (ja)	2004-01-29	2011-11-16	大日本住友製薬株式会社	ビグアナイド系薬物の内服製剤

2006
- 2006-04-26 PT PT06745689T patent/PT1878426E/pt unknown
- 2006-04-26 KR KR1020077026775A patent/KR20080007371A/ko not_active Ceased
- 2006-04-26 EP EP06745689A patent/EP1878426B1/en not_active Not-in-force
- 2006-04-26 CN CN2006800218325A patent/CN101198319B/zh not_active Expired - Fee Related
- 2006-04-26 EP EP10003548A patent/EP2204169A1/en not_active Withdrawn
- 2006-04-26 SI SI200630749T patent/SI1878426T1/sl unknown
- 2006-04-26 CA CA2607419A patent/CA2607419C/en not_active Expired - Fee Related
- 2006-04-26 US US11/912,463 patent/US8192761B2/en not_active Expired - Fee Related
- 2006-04-26 JP JP2007514762A patent/JP5084499B2/ja not_active Expired - Fee Related
- 2006-04-26 WO PCT/JP2006/308711 patent/WO2006118137A1/ja not_active Ceased
- 2006-04-26 DE DE602006014958T patent/DE602006014958D1/de active Active
- 2006-04-26 PL PL06745689T patent/PL1878426T3/pl unknown
- 2006-04-26 ES ES06745689T patent/ES2343432T3/es active Active
2010
- 2010-09-02 CY CY20101100805T patent/CY1110756T1/el unknown

Also Published As

Publication number	Publication date
CA2607419A1 (en)	2006-11-09
JP5084499B2 (ja)	2012-11-28
EP1878426A1 (en)	2008-01-16
SI1878426T1 (sl)	2010-09-30
EP2204169A1 (en)	2010-07-07
US8192761B2 (en)	2012-06-05
CN101198319B (zh)	2012-08-01
ES2343432T3 (es)	2010-07-30
PL1878426T3 (pl)	2010-11-30
WO2006118137A1 (ja)	2006-11-09
EP1878426B1 (en)	2010-06-16
US20090130215A1 (en)	2009-05-21
PT1878426E (pt)	2010-06-28
CN101198319A (zh)	2008-06-11
CY1110756T1 (el)	2015-06-10
EP1878426A4 (en)	2008-12-24
JPWO2006118137A1 (ja)	2008-12-18
DE602006014958D1 (de)	2010-07-29
CA2607419C (en)	2014-06-17
HK1117381A1 (en)	2009-01-16

Publication	Publication Date	Title
KR101590115B1 (ko)	2016-02-01	약학 조성물
AU609988B2 (en)	1991-05-09	Pharmaceutical compositions
JP5315056B2 (ja)	2013-10-16	固結抑制粒状製剤
EA002608B1 (ru)	2002-06-27	Фармацевтические композиции, содержащие шипучую кислотно-основную пару
RU2583935C2 (ru)	2016-05-10	Фармацевтическая композиция для перорального введения с маскированным вкусом и способ ее получения
HK1213814A1 (zh)	2016-07-15	双氯芬酸制剂和使用方法
EP1945190A1 (en)	2008-07-23	Effervescent metformin composition and tablets and granules made therefrom
JPH07501533A (ja)	1995-02-16	エバスタイムまたはその類似体に基づく医薬組成物
KR20080007371A (ko)	2008-01-18	비구아니드 화합물 함유 과립성 제제
TW550082B (en)	2003-09-01	Disintegrant
US20080161417A1 (en)	2008-07-03	Xylitol Granules Capable of Directly Being Compressible Into Tablets and Preparation Process Thereof
JP2002193839A (ja)	2002-07-10	ココア製剤
EP2726063A1 (en)	2014-05-07	Ibuprofen chewable tablet
JP2001294524A (ja)	2001-10-23	アセトアミノフェン配合内服固形製剤
JP4860486B2 (ja)	2012-01-25	ポビドンヨードを含有する口腔内崩壊型の固形製剤
HK1145436A (en)	2011-04-21	Granular preparation containing biguanide compound
HK1117381B (en)	2011-01-07	Granular preparation containing biguanide compound
CN117357481A (zh)	2024-01-09	一种口服掩味药物组合物的制备工艺
JPS6115844A (ja)	1986-01-23	医薬組成物
HK1124521A (en)	2009-07-17	Diclofenac formulations and methods of use
HK1010100B (en)	2002-04-12	Rapidly disintegrating formulation comprising tramadol or a tramadol salt

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