KR20030043520A - Oral compositions against halitosis - Google Patents

Abstract

PURPOSE: Provided is an oral composition against halitosis, which is excellent in inhibition of halitosis and oral hygiene, by using oral sterilizing agent, oral inflammation inhibitor and halitosis inducing material remover. CONSTITUTION: An oral composition is characterized by comprising 0.01-1 wt.% of xanthorrhizol, 0.001-2 wt.% of Ulmi cortex extract, dipotassium glycyrrhizinate or the mixture thereof, 0.01-2 wt.% of Paeonia suffruticosa roots, and 0.01-1 wt.% of a shampinion extract. It can be formulated into chewing gum, edible file, mouth spray, tooth paste and the like.

Description

Oral hygiene-promoting composition excellent in bad breath suppression {ORAL COMPOSITIONS AGAINST HALITOSIS}

[Industrial use]

The present invention relates to an oral hygiene-promoting composition excellent in suppressing bad breath, and more particularly to oral hygiene-promoting compositions for inhibiting bad breath by inhibiting and removing bacterial oral inflammation and bad breath-causing substances that cause bad breath. It is about.

[Prior art]

Bad breath is generally caused by oral diseases such as acquired systemic diseases or oral inflammation, or when proteins, food residues, etc. in saliva are decomposed by microorganisms in the oral cavity to produce substances causing bad smell. The main components causing bad breath are volatile sulfides (Volatile Sulfide Compounds (VSC)), which include hydrogen sulfide (H ₂ S), methyl mercaptan (CH ₃ SH), dimethyl mercaptan ( CH ₃ ) ₂ S], and methylmercaptan, in particular, is known as a main component of disgusting smell during bad breath. In addition, the gas of the intestinal rot product is also absorbed by the intestinal tract in the stomach, and is delivered to the lungs through the blood and through the exhaled breath.

As a method for removing such volatile sulfides, Korean Patent Publication No. 1997-8154 and Japanese Patent Laid-Open Publication No. 60-75418 disclose that suppressing bad breath by removing volatile sulfides.

However, in order to effectively suppress bad breath, oral microorganisms must be removed, and oral inflammation must be treated. In addition, bad breath-causing substances generated in the oral cavity and intestine should be removed. However, these methods have not yet solved these problems, and there is a need for the development of new oral hygiene composition.

In order to solve the problems of the prior art as described above, an object of the present invention is to provide an oral hygiene-promoting composition excellent in the antibacterial ability, oral anti-inflammatory effect, and the ability to remove bad breath-causing substances against oral microorganisms. It is done.

In order to achieve the above object, the present invention provides a composition for promoting oral hygiene, a) xantorisol; b) milky skin extract, licorice acid, or mixtures thereof; And c) neck skin extract; And d) provides an oral hygiene-promoting composition excellent in inhibiting bad breath, including the championion extract.

More specifically, the composition for promoting oral hygiene of the present invention comprises a) 0.01 to 1% by weight of xantolizol; b) 0.001 to 2% by weight of milky skin extract, licorice acid, or mixtures thereof; and c) 0.01 to 2% by weight of skin extract; And d) 0.01 to 1% by weight of championion extract.

Hereinafter, the present invention will be described in detail.

In order to solve the problems, the present inventors have repeatedly conducted a bad breath removal study, as a result of the excellent antimicrobial activity against oral microorganisms Xantholizol, oral anti-inflammatory effect milk milk extract or licorice acid, and occur in the oral cavity The present invention was completed by revealing that it is possible to effectively suppress bad breath when a mixture of bark skin extract, which is effective in adsorbing and removing bad breath-causing substances, and a championion extract, which is excellent in removing gas of decay products generated in the intestine. It was.

In the composition for promoting oral hygiene of the present invention, a) xantholizole is used to enhance the antimicrobial activity against oral microorganisms. Xanthozol is an antimicrobial component extracted from Curcuma xanthothiza Roxb. The curcuma zantorija is a traditional Indonesian medicinal plant known as Java turmeric as a ginger plant, and is known to have various physiological activities such as triglyceride reducing action, anticancer properties, and serum cholesterol reducing effect. In addition, since the Curcuma Xantori is a material that has been used as a tea in Indonesia for a long time, the human stability is already secured by the ingestion of the body, and it is an extremely safe plant with little irritation to the skin and mucous membranes. The method for obtaining xantholizol from the Curcuma Xantoriza is described in detail in Korean Patent Publication Nos. 2000-73295 and 2000-000342.

In the composition for promoting oral hygiene according to the present invention, the content of xantolizole is preferably used in 0.01 to 1% by weight based on the total amount of the composition. If the content of the xantholizole is less than 0.01% by weight can not be expected to inhibit bad breath by the bactericidal effect, when the content exceeds 1% by weight is difficult to apply the product is difficult and uneconomically unfavorable.

In addition, in the composition for promoting oral hygiene of the present invention, b) milky skin extract, licorice acid or a mixture thereof is used to improve oral anti-inflammatory efficacy.

Yubaekpi, which is a raw material for obtaining the milky extract, is obtained by extracting the roots of the stem or root of the elm tree of the elm family and dried in the sun. The components of the milky skin include procyanidins, beta-cyterol (β-siterol), and the like. The baekbaekpi is a material that has been used for a long time in medicinal herbs and medicinal, it is an extremely safe plant that has already secured the human stability according to the intake of the body, and almost no irritation to the skin and mucous membranes.

In addition, the licorice acid is a component that is purified from licorice and is a component that shows an excellent effect on anti-inflammatory.

In the composition for promoting oral hygiene of the present invention, the content of milk extract, licorice or a mixture thereof is preferably used in an amount of 0.001 to 2% by weight based on the total amount of the composition. If the content of the milk extract, licorice acid or a mixture thereof is less than 0.001% by weight, anti-inflammatory effect can not be expected, if it exceeds 2% by weight it is difficult to expect an increase in the anti-inflammatory effect of the increase in the content, and Because of its compatibility, there is difficulty in applying the product.

In addition, in the composition for promoting oral hygiene of the present invention, c) neck extract and d) champinion extract are used to remove bad breath-causing substances.

The bark skin is obtained by harvesting roots in the fall from the peony (or herds : Peony, Paeoniaceae) whose scientific name is Paeonia suffruticosa Andrews, and dried only the bark in the sun. Known chemical constituents of the bark skin include Paeonol and its glycosides, and other benzoic acid, campesterol and the like. Neck skin has been used as a sedative, antipyretic, and inflammatory medicine as a heat-fever medicine in oriental medicine. The bark skin is also a material that has been used in oriental medicine for a long time, and the human safety is already secured according to the intake of the body, and it is an extremely safe plant with little irritation to the skin and mucous membranes.

In the composition for promoting oral hygiene of the present invention, the content of the bark skin is preferably used in 0.01 to 2% by weight based on the total amount of the composition. If the content of the bark skin is less than 0.01% by weight can not be expected to inhibit the bad breath, if it exceeds 2% by weight it is difficult to expect an increase in the bad breath inhibitory effect due to the increase in content, difficult to apply the product due to the compatibility with the formulation There is this.

The champinion extract is an extract of the matsutake mushroom (Agaricus bisporous) and suppresses the occurrence of bad breath and body odor components methylmercaptan, ammonia and amines by addition and neutralization reaction with odor generating components It acts to suppress or eliminate body odor. In addition, the pine mushroom is a material that has been used for food, its extract is also an extremely safe plant that has already secured the human stability according to the intake of the body, almost no irritation to the skin and mucous membranes.

In the composition for promoting oral hygiene of the present invention, the content of the champinion extract is preferably used in 0.01 to 1% by weight based on the total amount of the composition. If the content of the champignion extract is less than 0.01% by weight anti-inflammatory effect can not be expected, if it exceeds 1% by weight it is difficult to expect an increase in the anti-inflammatory effect of the increase in content, the compatibility with the formulation is poor Difficult to apply

The natural extracts can be prepared by a general extraction method, briefly described as follows.

Each natural product may be ground to a size of 10 to 200 mesh, the extraction powder is added to the ground powder, cooled for 48 hours, filtered, and the filtered extract solution may be concentrated to obtain each natural product extract. At this time, the extraction solvent used may be one or more selected from the group consisting of purified water, methanol, ethanol, propanol, butanol, ethylene glycol, propylene glycol, 1,3-butylene glycol, ethyl acetate, and acetone.

In the composition for promoting oral hygiene of the present invention, the formulation may be prepared in various formulations of oral hygiene enhancers such as chewing gum, dietary film, mouse spray, dentifrice and toothpaste, and each composition may be prepared by conventional methods. Do. Examples of the chewing gum, dietary film, and mouse spray composition among them are as follows.

First, the composition for promoting oral hygiene of the chewing gum formulation of the present invention is the above-mentioned xantolizole, milky skin extract and / or licoriceic acid in the existing chewing gum composition including a gum base, a sweetener, a plasticizer, an emulsifier, and other additives, and Thickened skin extract and champinion extract are used as main active ingredients of bad breath control.

The content of the gum base is preferably used in 15 to 50% by weight based on the total amount of the composition.

The sweetener is preferably used in an amount of 40 to 80% by weight based on the total amount of the composition, and includes 40 to 70% by weight of sugar, 4 to 15% by weight of glucose, and 4 to 15% by weight of starch syrup as usual.

The plasticizer may be used, such as glycerol or lecithin, the content of the plasticizer is preferably used in 0.05 to 0.2% by weight based on the total amount of the composition.

The emulsifier is usually used sucrose fatty acid ester, the content of the emulsifier is preferably used in 0.1 to 0.3% by weight.

As other additives, a small amount of fragrance, colorant, acidulant, sugar alcohol and the like can be used.

In addition, when describing the dietary film formulation in the composition for promoting oral hygiene of the present invention.

According to the present invention, by using a variety of known water-soluble polymers to prepare a dietary film containing a bad breath inhibiting component and adhered to the oral mucosa, bad breath can be suppressed by the bad breath inhibiting component is slowly released while the film is dissolved in saliva. Drug delivery studies using these formulations have been progressing in relation to medicines, but studies on bad breath control have not been conducted. The formulation by the dietary film does not need to spit the medicament, unlike the formulation such as fern because the film is dissolved in saliva, there is an advantage that does not remain unpleasant, such as foreign matter or stickiness does not remain insoluble components in the oral cavity.

The dietary film composition of the present invention comprises the above-mentioned xantorizole, milky skin extract and / or licoriceic acid, and chlorophyll extract in a dietary film composition comprising a water-soluble polymer, a plasticizer, and other antioxidants, preservatives, flavoring agents, and coloring agents. Champignion extract is used as the main active ingredient of bad breath control.

In the mucoadhesive dietary film composition of the present invention, the water-soluble polymer may be a hydrophilic polymer. The hydrophilic water-soluble polymer is hydroxypropyl cellulose (Hydroxypropyl cellulose-Klucel ^TM ), hydroxypropyl methyl cellulose (Hydroxypropyl methylcellulose), hydroxy ethyl cellulose (Hydroxy ethylcellulose), ethyl cellulose (ethylcellulose), carboxymethyl cellulose (Carboxymethylcellulose) , Dextran, gaur-gum, polyvinyl pyrrolidone (PVP), pectins, starcrs, gelatin, casein, sodium alginate, polyethylene glycol (polyethlyene glycol), and one or more selected from the group consisting of polyvinyl glycol (polyvinyl glycol) can be used, but is not limited to the above-mentioned polymer, various other water-soluble polymer can be used. The content of the water-soluble polymer is preferably used in 40 to 95% by weight based on the total amount of the composition.

The plasticizer may be one or more selected from the group consisting of glycols such as propylene glycol and ethylene glycol, glycerin, sorbitol, mineral oil and vegetable oil. The amount of the plasticizer is preferably used in 1 to 10% by weight based on the total amount of the composition.

As other conventional components, for example, small amounts of antioxidants, preservatives, flavoring agents, sweetening agents or coloring agents can be used.

In addition, the mouse spray composition of the present invention is a conventional mouse spray composition comprising ethanol, wetting agents, surfactants, sweeteners, fragrances and other additives described above in the xantorizol, milky skin extract and / or licoriceic acid, and the ethanol extract and siamese Pinion extract is used as the main active ingredient of bad breath suppression.

The content of the ethanol is preferably used in 5 to 70% by weight based on the total amount of the composition.

The humectant may be glycerin, sorbitol, propylene glycol and the like. The content of the humectant is preferably used in 3 to 40% by weight of the total amount of the composition.

The surfactant may be a polyoxyethylene polyoxypropylene copolymer polymer, polyoxyethylene cured castor oil and the like. The amount of the surfactant is preferably 0.1 to 5% by weight based on the total amount of the composition,

The sweetener may be used sodium saccharin, sorbitol, aspartame, xylitol and the like. The content of the sweetener is preferably used in 0.001 to 0.3% by weight based on the total amount of the composition.

The fragrance may be a fragrance substance used in a conventional toothpaste or a substance used as a food fragrance. The amount of the perfume is preferably used in 0.01 to 5% by weight based on the total amount of the composition.

In addition, other additives may be used a small amount of auxiliary agents, preservatives, buffers, pigments and the like.

Hereinafter, the present invention will be described with reference to the following Examples and Comparative Examples. However, these examples are only for illustrating the present invention, and the present invention is not limited thereto.

EXAMPLE

Example 1 Preparation of Chewing Gum Composition

Chewing gum of the present invention (Examples 1-1 to 1-4) and chewing gum (Comparative Examples 1-1 to 1-4) containing only or part of the bad breath inhibiting component of the present invention were prepared using the components shown in Table 1 as main components. It was.

(Unit: g weight) Example Comparative example 1-1 1-2 1-3 1-4 1-1 1-2 1-3 1-4 Xantorisol 0.1 One 5 10 - - One - Milky Skin Extract 0.01 One 10 20 - - - One Peel Extract 0.1 One 10 20 - One - - Champagne Extract 0.1 One 5 10 - One - - Gum base 250 250 250 250 250 250 250 250 Sugar 520 520 520 520 520 520 520 520 glucose 65 65 65 65 65 65 65 65 corn syrup 65 65 65 65 65 65 65 65 Fruit flavoring 25 25 25 25 25 25 25 25 Glycerol 2 2 2 2 2 2 2 2 Sucrose Fatty Acid Esters 2 2 2 2 2 2 2 2 Citric acid 5 5 5 5 5 5 5 5 Sorbitol 4 4 4 4 4 4 4 4

Experimental Example 1. Comparative experiment of bad breath inhibitory effects on Examples 1-1 to 1-4 and Comparative Examples 1-1 to 1-4

In this experiment, 40 men and women without dental caries were selected and 5 subjects per chewing gum were tested. The bad breath inhibition was measured by using a Halimeter instrument and sensory evaluation.

After eating the same meal, the bad breath was measured with Halimeter to determine the initial level of bad breath, chewed with each chewing gum for 30 minutes, and then bad breath was measured again with Halimeter. The usage of Halimer is as follows. For 2 minutes before the measurement, the mouth was closed and breathed only through the nose. During the measurement, the straw was put into the mouth about 1.5 cm and maintained for about 15 seconds. At this time, the straw did not touch the tongue, the lips were kept about 3-4 mm apart, and the breathing was done only with the nose. Halimeter measurements are in ppb, and the bad breath inhibition rates of each chewing gum were compared by averaging the bad breath measurements obtained from the respective test subjects. The bad breath inhibition rate was calculated through the following equation.

[Equation 1]

% Of bad breath suppressed = (early measured value-measured value after chewing gum chewing) ÷ (initial measured value) × 100

In the sensory evaluation, five sensory assessors were used to measure the degree of bad breath on a five-point scale as described below, and the average value was used.

5 points | pieces: The bad breath inhibitory effect is good. 3 points | pieces: The bad breath inhibitory effect is moderate.

1 point | piece: Bad breath control effect is bad.

After chewing each chewing gum, the results for the bad breath inhibitory effect are shown in Table 2 below.

Average bad breath inhibition rate (%) Sensory evaluation Example 1-1 29 2.8 1-2 48 4.2 1-3 62 4.4 1-4 86 4.8 Comparative example 1-1 23 2.4 1-2 40 3.8 1-3 37 3.4 1-4 37 3.2

In Table 2, the bad breath produced after eating showed an average inhibition rate of 23% even in Comparative Example 1-1, which contained no active ingredient when measured after chewing chewing gum, but the inhibition rate was not large as in Example. . In addition, Comparative Examples 1-2, 1-3, and 1-4, in which the active ingredients were added by function of the active ingredients, respectively, compared to Comparative Example 1-1, but the inhalation inhibition rate was increased, but each Example in which all the active ingredients were added Rather than a large rate of inhibition of bad breath, xantolizol, milky skin extract, bark skin extract, and champinion extract were found to show synergistic effect.

In addition, the results of the sensory evaluation also showed that the case of using the xantholizol and milky skin extract together with the bark skin extract and the champinion extract showed a higher value than the comparative example, which is superior to the bad breath inhibitory effect. .

Therefore, synergism of each component when using xantolizol as an oral fungicide, milky white skin extract as an anti-inflammatory agent, velvet skin extract as an inhalation agent, and champinion extract as an odor removing agent from intestinal erosion products are used. It can be seen that it can be effectively suppressed.

Example 2. Preparation of Dietary Film Compositions

Next, the dietary film containing the components as shown in Table 3 as a main component (Examples 2-1 to 2-4) and no or only part of bad breath inhibitory components (Comparative Examples 2-1 to 2- 4) was prepared.

(Unit: g weight) Example Comparative example 2-1 2-2 2-3 2-4 2-1 2-2 2-3 2-4 Xantorisol 0.01 0.1 0.5 One - 0.1 - - Milky Skin Extract 0.001 0.1 One 2 - - - 0.1 Peel Extract 0.01 0.1 0.5 One - - 0.1 - Champagne Extract 0.01 0.1 One 2 - 0.1 - - Hydroxypropyl cellulose 50 50 50 50 50 50 50 50 PVP 30 30 30 30 30 30 30 30 glycerin 5 5 5 5 5 5 5 5 Sorbitol 4 4 4 4 4 4 4 4 Fruit flavoring 5 5 5 5 5 5 5 5 water 100 100 100 100 100 100 100 100 ethanol 100 100 100 100 100 100 100 100

Experimental Example 2. Comparative experiment of bad breath inhibitory effect on Examples 2-1 to 2-4 and Comparative Examples 2-1 to 2-4

For this study, 40 men and women without dental caries were selected and 5 dietary films were included. The bad breath inhibition was measured by using a Halimeter instrument and sensory evaluation.

After the same meal, the bad breath was measured with a Halimeter to determine the initial degree of bad breath. Each dietary film was adhered to the tongue, and after the film was completely dissolved in saliva, bad breath was measured again using a Halimeter. The experimental measurement method of the Halimeter and sensory evaluation was the same as in the previous Experimental Example 1.

The results for the bad breath inhibitory effect after taking each dietary film are shown in Table 4 below.

Average bad breath inhibition rate (%) Sensory evaluation Example 2-1 29 2.8 2-2 45 3.8 2-3 62 4.4 2-4 87 4.6 Comparative example 2-1 15 1.8 2-2 38 3.4 2-3 37 3.4 2-4 34 3.2

In Table 4, an average of 15% inhibition was observed in Comparative Example 2-1 containing no active ingredient, but the inhibition was not greater than that of the Example. In addition, Comparative Examples 2-2, 2-3, and 2-4, in which the active ingredients were added by function of the active ingredients, respectively, compared to Comparative Example 2-1 containing no active ingredients, the inhibition rate of bad breath was increased. It was found that synergism with each other when combined with xantolizole, pelvic bark extract, champinion extract and milky bark extract was not greater than the example of adding all the ingredients. In addition, as the content of the active ingredient increases, the rate of bad breath inhibition also increases with Example 2 comprising about 1% of xantholizol, about 1% of milky skin extract, about 2% of bark extract, and about 1% of championion extract. -4 showed an average bad breath inhibition rate of 87%.

In addition, the results of the sensory evaluation also showed that the example using the xantholizol, the milky skin extract, the velvet extract, and the championion extract showed a higher value than the comparative example, showing that the bad breath inhibitory effect was more excellent.

Therefore, synergism of each component in the case of using xantholizol as an oral fungicide, milky white skin extract as an anti-inflammatory agent, velvet skin extract as a bad breath-causing substance remover, and champinion extract as an odor removing agent from intestinal rot products, It can be seen that it can be effectively suppressed.

Example 3. Preparation of Mouse Spray Compositions

Mouse sprays of the present invention (Examples 3-1 to 3-4) and the bad breath-inhibiting component containing only a part of the components as shown in Table 5 (Comparative Examples 3-1 to 3-4) Was prepared.

(Unit: weight%) Example Comparative example 3-1 3-2 3-3 3-4 3-1 3-2 3-3 3-4 Xantorisol 0.01 0.1 0.5 One - 0.1 - - Milky Skin Extract 0.001 0.1 One 2 - - - 0.1 Peel Extract 0.01 0.1 One 2 - - 0.1 - Champagne Extract 0.01 0.1 0.5 One - - 0.1 - ethanol 60 60 60 60 60 60 60 60 glycerin 7 7 7 7 7 7 7 7 Sodium fluoride 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 Sodium citrate 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 Citric acid 0.005 0.005 0.005 0.005 0.005 0.005 0.005 0.005 Zaccarin Sodium 0.011 0.011 0.011 0.011 0.011 0.011 0.011 0.011 F-127 One One One One One One One One Methylparaben 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Propylparaben 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 Combination spices 0.12 0.12 0.12 0.12 0.12 0.12 0.12 0.12 Purified water Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount Remaining amount

Experimental Example 3. Comparative experiment on the effects of bad breath

In this experiment, 40 men and women without dental caries were selected and 5 mouse sprays were used as the test subjects. The bad breath inhibition was measured by using a Halimeter instrument and sensory evaluation.

After the same meal, the bad breath was measured with a Halimeter to determine the initial degree of bad breath. Each mouse spray was sprayed five times evenly in the mouth, and again bad breath was measured by Halimeter, at which time sensory evaluation was performed together. The experimental measurement method of the Halimeter and sensory evaluation was the same as in the previous Experimental Example 1.

The results for the bad breath inhibitory effect after applying each mouse spray are shown in Table 6 below.

Average bad breath inhibition rate (%) Sensory evaluation Example 3-1 25 2.8 3-2 48 3.8 3-3 65 4.4 3-4 86 4.6 Comparative example 3-1 23 2.6 3-2 40 3.4 3-3 40 3.2 3-4 38 3.2

As shown in Table 6, Comparative Example 3-1 containing no active ingredient at all showed an inhibition rate of 23% on average, showing a similar inhibition rate as that of Example 3-1 containing the least amount of active ingredient, but more than that. The inhibition rate was not large compared with Examples 3-2, 3-3, and 3-4 containing the active ingredient. In addition, Comparative Examples 3-2, 3-3, and 3-4, in which the active ingredients were added for each function of the active ingredients, showed an increase in the bad breath inhibition rate compared to Comparative Example 3-1, which contained no active ingredients, It was found that the rate of bad breath inhibition was not greater than that of Example 3-2, in which all of the active ingredients were added, and thus synergistic effects were obtained when xantolizole, velvet skin extract, championion extract, and milky skin extract were used together. In addition, as the content of the active ingredient increased, the rate of bad breath was also increased with 86% in Example 3-4 containing 1% of xantholizol, 1% of milk extract, 2% of nutmeg extract, and 1% of championion extract. Average bad breath inhibition rate was shown.

In addition, the results of the sensory evaluation also showed a higher value than the comparative example in the case of using the xantholizol, milk white skin extract, velvet skin extract, and championion extract showed that the bad breath inhibitory effect was more excellent.

Therefore, in case of using oral sterilization, oral and intestinal decay products, and using xantolizol, milk white skin extract, championion extract and velvet skin extract, which have anti-inflammatory effects, bad breath can be effectively prevented by synergistic action of each component. It can be seen that it can be suppressed.

As described above, according to the present invention using oral fungicides, oral inflammation inhibitors, and bad breath-causing substances remover, oral hygiene excellent in the bad breath inhibitory effect of various formulations such as chewing gum, dietary film, mouth spray (mouth spray), etc. Promoting compositions can be provided.

Claims (3)

In the composition for promoting oral hygiene, a) xantholizole; b) milky skin extract, licorice acid, or mixtures thereof; And c) neck skin extract; And d) championion extract Oral hygiene composition excellent in inhibiting bad breath comprising a. The method of claim 1, a) 0.01 to 1 weight percent of xantholizol; b) 0.001 to 2% by weight of milk extract, licorice acid, or mixtures thereof; And c) 0.01-2% by weight of the extract of bark; And d) 0.01 to 1% by weight of championion extract Oral hygiene-promoting composition excellent in inhibiting bad breath, characterized in that it comprises a. According to claim 1, wherein the formulation of the composition for promoting oral hygiene is a chewing gum, dietary film (edible film), mouth spray (mouth spray), toothpaste, or toothpaste excellent oral hygiene enhancement effect, characterized in that the toothpaste. Composition.