KR20020009635A - Ｉｌ-8 수용체 길항제 - Google Patents

Ｉｌ-8 수용체 길항제 Download PDF

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Publication number: KR20020009635A
Authority: KR; South Korea
Prior art keywords: alkyl; optionally substituted; heterocyclic; heteroaryl; aryl
Prior art date: 1999-06-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

KR1020017016140A

Other languages

English (en)

Korean (ko)

Inventor

데보라 엘. 브라이언

존 지. 글리슨

캐서린 엘. 위도우슨

그레고리 엠. 벤슨

Original Assignee

스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스

스미스클라인 비참 코포레이션

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-16

Filing date

2000-06-16

Publication date

2002-02-01

2000-06-16 Application filed by 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스, 스미스클라인 비참 코포레이션 filed Critical 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스

2002-02-01 Publication of KR20020009635A publication Critical patent/KR20020009635A/ko

Status Withdrawn legal-status Critical Current

Links

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229920001277 pectin Polymers 0.000 description 1
239000008188 pellet Substances 0.000 description 1
230000035515 penetration Effects 0.000 description 1
RGSFGYAAUTVSQA-UHFFFAOYSA-N pentamethylene Natural products C1CCCC1 RGSFGYAAUTVSQA-UHFFFAOYSA-N 0.000 description 1
ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 description 1
229940117953 phenylisothiocyanate Drugs 0.000 description 1
239000002953 phosphate buffered saline Substances 0.000 description 1
230000035479 physiological effects, processes and functions Effects 0.000 description 1
230000035790 physiological processes and functions Effects 0.000 description 1
229920000728 polyester Polymers 0.000 description 1
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230000002335 preservative effect Effects 0.000 description 1
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125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 description 1
238000001243 protein synthesis Methods 0.000 description 1
239000003586 protic polar solvent Substances 0.000 description 1
238000000746 purification Methods 0.000 description 1
125000002294 quinazolinyl group Chemical group N1=C(N=CC2=CC=CC=C12)* 0.000 description 1
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125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
150000003335 secondary amines Chemical class 0.000 description 1
230000036303 septic shock Effects 0.000 description 1
RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
235000012239 silicon dioxide Nutrition 0.000 description 1
CQLFBEKRDQMJLZ-UHFFFAOYSA-M silver acetate Chemical compound [Ag+].CC([O-])=O CQLFBEKRDQMJLZ-UHFFFAOYSA-M 0.000 description 1
229940071536 silver acetate Drugs 0.000 description 1
229910001923 silver oxide Inorganic materials 0.000 description 1
239000002002 slurry Substances 0.000 description 1
150000003384 small molecules Chemical class 0.000 description 1
210000000329 smooth muscle myocyte Anatomy 0.000 description 1
239000000344 soap Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
229910000033 sodium borohydride Inorganic materials 0.000 description 1
239000012279 sodium borohydride Substances 0.000 description 1
241000894007 species Species 0.000 description 1
238000001228 spectrum Methods 0.000 description 1
235000011150 stannous chloride Nutrition 0.000 description 1
239000012258 stirred mixture Substances 0.000 description 1
125000005504 styryl group Chemical group 0.000 description 1
208000011117 substance-related disease Diseases 0.000 description 1
125000000547 substituted alkyl group Chemical group 0.000 description 1
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239000000758 substrate Substances 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
239000000375 suspending agent Substances 0.000 description 1
238000007910 systemic administration Methods 0.000 description 1
239000000454 talc Substances 0.000 description 1
229910052623 talc Inorganic materials 0.000 description 1
235000012222 talc Nutrition 0.000 description 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 1
125000001981 tert-butyldimethylsilyl group Chemical group [H]C([H])([H])[Si]([H])(C([H])([H])[H])[*]C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
229950011008 tetrachloroethylene Drugs 0.000 description 1
VLLMWSRANPNYQX-UHFFFAOYSA-N thiadiazole Chemical compound C1=CSN=N1.C1=CSN=N1 VLLMWSRANPNYQX-UHFFFAOYSA-N 0.000 description 1
150000003557 thiazoles Chemical class 0.000 description 1
125000001544 thienyl group Chemical group 0.000 description 1
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AXZWODMDQAVCJE-UHFFFAOYSA-L tin(II) chloride (anhydrous) Chemical compound [Cl-].[Cl-].[Sn+2] AXZWODMDQAVCJE-UHFFFAOYSA-L 0.000 description 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
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150000003852 triazoles Chemical class 0.000 description 1
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JLTRXTDYQLMHGR-UHFFFAOYSA-N trimethylaluminium Chemical compound C[Al](C)C JLTRXTDYQLMHGR-UHFFFAOYSA-N 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Tropical Medicine & Parasitology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Biotechnology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

KR1020017016140A 1999-06-16 2000-06-16 Ｉｌ-8 수용체 길항제 Withdrawn KR20020009635A (ko)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US13967499P	1999-06-16	1999-06-16
US60/139,674		1999-06-16
PCT/US2000/016813 WO2000076516A1 (en)	1999-06-16	2000-06-16	Il-8 receptor antagonists

Publications (1)

Publication Number	Publication Date
KR20020009635A true KR20020009635A (ko)	2002-02-01

Family

ID=22487784

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1020017016140A Withdrawn KR20020009635A (ko)	1999-06-16	2000-06-16	Ｉｌ-8 수용체 길항제

Country Status (22)

Country	Link
EP (1)	EP1191934A4 (xx)
JP (1)	JP2003501471A (xx)
KR (1)	KR20020009635A (xx)
CN (1)	CN1494424A (xx)
AR (1)	AR029368A1 (xx)
AU (1)	AU766086B2 (xx)
BR (1)	BR0010985A (xx)
CA (1)	CA2377397A1 (xx)
CZ (1)	CZ20014490A3 (xx)
EC (2)	ECSP003525A (xx)
HK (1)	HK1044716A1 (xx)
HU (1)	HUP0202019A3 (xx)
IL (1)	IL146214A0 (xx)
MX (1)	MXPA01013287A (xx)
NO (1)	NO20016065L (xx)
NZ (1)	NZ515232A (xx)
PE (1)	PE20010319A1 (xx)
PL (1)	PL352218A1 (xx)
TR (1)	TR200103690T2 (xx)
UY (1)	UY26209A1 (xx)
WO (1)	WO2000076516A1 (xx)
ZA (1)	ZA200110203B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6642215B2 (en) *	2001-05-24	2003-11-04	Leo Pharma A/S	Method of modulating NF-kB activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2060682T3 (es) *	1988-03-30	1994-12-01	Warner Lambert Co	N-((fenil(2,6-disubstituido))-n'-aril)ureas como agentes antihipercolesterolemicos y antiateroscleroticos.
US5780483A (en) *	1995-02-17	1998-07-14	Smithkline Beecham Corporation	IL-8 receptor antagonists
AR008290A1 (es) *	1996-08-15	1999-12-29	Smithkline Beecham Corp	Nuevos compuestos que contienen guanidina utiles como antagonistas de los receptores de il-8, composiciones farmaceuticas que los contienenprocedimiento para la preparacion de dichos compuestos y procedimiento para la preparacion de intermediarios.

2000
- 2000-06-12 EC EC2000003525A patent/ECSP003525A/es unknown
- 2000-06-14 PE PE2000000589A patent/PE20010319A1/es not_active Application Discontinuation
- 2000-06-14 UY UY26209A patent/UY26209A1/es not_active Application Discontinuation
- 2000-06-14 AR ARP000102925A patent/AR029368A1/es not_active Application Discontinuation
- 2000-06-16 MX MXPA01013287A patent/MXPA01013287A/es unknown
- 2000-06-16 IL IL14621400A patent/IL146214A0/xx unknown
- 2000-06-16 CA CA002377397A patent/CA2377397A1/en not_active Abandoned
- 2000-06-16 TR TR2001/03690T patent/TR200103690T2/xx unknown
- 2000-06-16 NZ NZ515232A patent/NZ515232A/xx unknown
- 2000-06-16 HK HK02106332.2A patent/HK1044716A1/zh unknown
- 2000-06-16 AU AU57482/00A patent/AU766086B2/en not_active Ceased
- 2000-06-16 HU HU0202019A patent/HUP0202019A3/hu unknown
- 2000-06-16 BR BR0010985-1A patent/BR0010985A/pt not_active IP Right Cessation
- 2000-06-16 WO PCT/US2000/016813 patent/WO2000076516A1/en not_active Ceased
- 2000-06-16 PL PL00352218A patent/PL352218A1/xx not_active Application Discontinuation
- 2000-06-16 EP EP00942933A patent/EP1191934A4/en not_active Withdrawn
- 2000-06-16 JP JP2001502849A patent/JP2003501471A/ja not_active Withdrawn
- 2000-06-16 CZ CZ20014490A patent/CZ20014490A3/cs unknown
- 2000-06-16 KR KR1020017016140A patent/KR20020009635A/ko not_active Withdrawn
- 2000-06-16 CN CNA008089205A patent/CN1494424A/zh active Pending
- 2000-08-14 EC EC2000003528A patent/ECSP003528A/es unknown
- 2000-12-12 ZA ZA200110203A patent/ZA200110203B/xx unknown
2001
- 2001-12-12 NO NO20016065A patent/NO20016065L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP0202019A3 (en)	2003-03-28
CZ20014490A3 (cs)	2002-07-17
PE20010319A1 (es)	2001-05-24
UY26209A1 (es)	2000-12-29
JP2003501471A (ja)	2003-01-14
HK1044716A1 (zh)	2002-11-01
HUP0202019A2 (en)	2002-10-28
ECSP003525A (es)	2002-01-25
CA2377397A1 (en)	2000-12-21
ZA200110203B (en)	2002-09-11
EP1191934A4 (en)	2004-02-04
AR029368A1 (es)	2003-06-25
IL146214A0 (en)	2002-07-25
AU5748200A (en)	2001-01-02
NO20016065D0 (no)	2001-12-12
MXPA01013287A (es)	2002-06-04
AU766086B2 (en)	2003-10-09
WO2000076516A1 (en)	2000-12-21
PL352218A1 (en)	2003-08-11
ECSP003528A (es)	2002-01-25
NO20016065L (no)	2001-12-12
BR0010985A (pt)	2002-03-26
TR200103690T2 (tr)	2002-05-21
EP1191934A1 (en)	2002-04-03
NZ515232A (en)	2004-02-27
CN1494424A (zh)	2004-05-05

Publication	Publication Date	Title
US6204294B1 (en)	2001-03-20	IL-8 receptor antagonists
US6218539B1 (en)	2001-04-17	IL-8 receptor antagonists
US5886044A (en)	1999-03-23	IL-8 receptor antagonists
US6005008A (en)	1999-12-21	IL-8 receptor antagonists
KR20000022273A (ko)	2000-04-25	Il-8 수용체 길항제
KR20000070368A (ko)	2000-11-25	인터루킨-8 수용체 길항제
KR20000022274A (ko)	2000-04-25	Il-8 수용체 길항제
US5955492A (en)	1999-09-21	Carboxylic acid indole inhibitors of chemokines
KR20030017526A (ko)	2003-03-03	Ｉｌ-８ 수용체 길항제
US6214881B1 (en)	2001-04-10	IL-8 receptor antagonists
JP2000513359A (ja)	2000-10-10	Ｉｌ―８受容体拮抗薬
KR20020010709A (ko)	2002-02-04	Ｉｌ-8 수용체 길항제
KR20020080460A (ko)	2002-10-23	Ｉｌ-８ 수용체 길항제
KR20020015347A (ko)	2002-02-27	Ｉｌ-8 수용체 길항제
KR20000070369A (ko)	2000-11-25	인터루킨-8 수용체 길항제
EP0971908B1 (en)	2004-06-30	Il-8 receptor antagonists
KR20040014901A (ko)	2004-02-18	Ｉｌ-８ 수용체 길항제
WO1998006398A1 (en)	1998-02-19	Il-8 receptor antagonists
KR20020091130A (ko)	2002-12-05	Ｉｌ-８ 수용체 길항제
KR20020009635A (ko)	2002-02-01	Ｉｌ-8 수용체 길항제
JP2002509105A (ja)	2002-03-26	Ｉｌ−８受容体アンタゴニスト
US20030225125A1 (en)	2003-12-04	IL-8 receptor antagonists
JP2000515495A (ja)	2000-11-21	Ｉｌ―８レセプターアンタゴニスト
KR20020091127A (ko)	2002-12-05	Ｉｌ-8 수용체 길항제
KR20020012275A (ko)	2002-02-15	Ｉｌ-8 수용체 길항제

Legal Events

Date	Code	Title	Description
2001-12-15	PA0105	International application	Patent event date: 20011215 Patent event code: PA01051R01D Comment text: International Patent Application
2002-02-01	PG1501	Laying open of application
2005-06-17	PC1203	Withdrawal of no request for examination
2005-06-17	WITN	Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid