KR20010020301A - Stable Herbal Dentifrice - Google Patents

Abstract

The present invention provides a dentifrice gel comprising up to 60% sodium bicarbonate, up to 5% natural ingredients and 2% flavourant in addition to the other dentifrice components.

Description

Stable Herbal Dentifrice

The dentifrice has been known for a long time and has been used to clean teeth and remove plaque. Skirt manufacturers are constantly seeking new ways to improve the beauty of their skirts to encourage compliance with oral health rules. With the improvement of flavor that has been practiced for many years, the appearance of traditional white paste toothpaste has been variously improved.

One of the most significant improvements in appearance was the introduction of the dentifrice gel. In lieu of opaque pastes, transparent or translucent gels have been provided to the public and have encouraged compliance with oral health rules.

Another concern in recent years for consumers has been the use of more types of "natural" raw materials in general products including dentifrices. Therefore, baking soda, which is a traditional skirting ingredient, has recently started to be used as a cleaning agent for skirting agents.

However, the problem of baking soda as a dentifrice component is stability. Baking soda (sodium bicarbonate) tends to decompose in combination with water. Thus, the shelf life of the baking soda dentifrice can be unacceptably short.

Delaney et al., US Patent No. 3,937,804, issued February 10, 1976 (all with the corresponding US Patent No. 3,943,240, issued March 9, 1976, are all assigned to the Colgate-Palmolive Company) at least about An example of a baking soda dentifrice is disclosed in which 20%, preferably 30%, sodium bicarbonate is mixed with water, polyol humectants, gelling or thickening agents and fluorides. The dentifrice exhibits a granular tissue appearance due to the macroscopic crystalline bicarbonate granules rather than the smooth continuous matrix. Baking soda appears to remain stable because it forms huge granules and is separated from the water.

US Patent No. 5,326,544 to Fitz, Jr., published July 5, 1994, relates to a sodium bicarbonate-containing oral hygiene composition using sodium carbonate as a stabilizing buffer.

US Pat. No. 4,623,536 to Winston et al., Published November 18, 1986, and US Pat. No. 4,721,614 to January 26, 1988, relate to toothpastes containing at least 60% sodium bicarbonate. More than 30% of the bicarbonate has a particle size of less than 25 microns, and bicarbonate is the only abrasive component of the dentifrice. The document claims that smaller particle size is the basis of the stability required for toothpaste. The Delaney patent discussed above is differentiated in that it maintains stability by stopping degassing of the dentifrice composition prior to complete degassing. Thus, Delaney's patent avoided raising the pH value unacceptably.

U.S. Patent 4,943,429, published July 24, 1990, relates to a dentifrice gel containing sodium bicarbonate. The dentifrice comprises up to about 60% by weight sodium bicarbonate and at least about 22% by weight humectants such as glycerol or sorbitol. It is preferable to use coarser bicarbonate at bicarbonate concentrations above 30%, because cobalt (greater than about 149 microns) grade bicarbonate can be used to increase the bicarbonate concentration in translucent gels.

Sodium bicarbonate and peroxide skirting agents have been provided in separate tubular forms to address stability issues, as in US Pat. No. 5,456,902 to Williams et al., October 10, 1995.

Baking soda can have good or bad effects on other ingredients in your dentifrice. For example, US Pat. Nos. 5,180,576 (published Jan. 19, 1993) and 5,318,773 (published June 7, 1994) to Winston et al. It relates to a dentifrice containing. The combination of sodium bicarbonate and pyrophosphate has been shown to be synergistic and claim less pyrophosphate. However, since bicarbonate precipitates pyrophosphate and is present in the state in which the pyrophosphate is almost insoluble in the dentifrice, the two components remain as separated solids in the dentifrice.

United States Patent No. 5,455,024 to Winston et al., Published October 3, 1995, relates to the use of a combination of zinc oxide and sodium bicarbonate in a dentifrice.

In addition to baking soda, other natural ingredients have been blended into the dentifrice. For example, US Pat. No. 5,149,521 to Hirose et al., Published September 22, 1992, relates to an oral care composition such as a dentifrice. The document describes compositions comprising powdered granules, menthol and basil, laurel, lavender or lactone. Powder feel is significantly reduced when using such compositions.

Examples of dentifrices using “natural” ingredients can be found in US Pat. No. 5,472,684 to Nabi et al., Published December 5, 1995. The patent claims that combinations of sesquiterpene alcohols such as thymol, eugenol and optionally farnesol, exhibit antimicrobial properties. Camomile, Myrrh Gum, Latania Root, Australian Tea Tree Oil, Eucalyptol, Sage Oil, Tulsi Oil, Neem Oil, Echininacea Extract, Rosemary Extract, Golden Seed Extract, A variety of natural ingredients can add flavor to the blend, such as passion flower extract, turmeric root extract, betel extract, sunphenon tea extract, and dandelion root extract.

US Pat. No. 4,812,306 to Cocherell et al., Published March 14, 1989, discloses anise oil, cloves oil, sasafras, peppermint, glycerin, corn starch, sweetener, sodium la It relates to a moisture-free dentifrice containing usyl sulphate, sodium bicarbonate and vegetable oils.

The problem with dentifrice gels containing natural ingredients is the liquid syneresis, ie, the tendency of the liquid components to separate in the gel. This problem can occur rapidly in compositions of high solid concentration, such as in dentifrices containing baking soda.

This study of natural remedies is not limited to dentifrices. For example, US Pat. No. 4,670,264 to Warren et al., Published June 2, 1987, discloses nutmeg, mace, kerosene, gilded muscle, myristicin, iso via inhalation or skin. It is directed to reducing stress by delivering elemycin or elemycin.

Zeines, U.S. Patent No. 5,378,465, issued January 3, 1995, discloses Echinacea, hydratis canadensis, sanguinaria canadensis, and quercus albe. ), An aqueous mouthwash comprising grape seed extract, aloe vera juice, water, vegetable glycerin and peppermint oil.

US Patent No. 5,043,153 to Videki et al., Published August 27, 1991, relates to compositions for the prevention and treatment of periodontitis. This composition comprises celandine, peppermint, marigold, thyme, millfoil, and optionally an aqueous solution of chamomile, melilot leaves, and cloves or arnica.

Noorlander, US Pat. No. 4,607,263, issued June 2, 1987, relates to a non-toxic fungicide comprising an Alantion, optionally ascorbic acid, chlorophyll or carotene.

Along with baking soda and other "natural" ingredients, skirting manufacturers are constantly looking for more effective skirting ingredients. Lukacovic, US Pat. No. 5,578,294, published November 26, 1996, relates to compositions for oral cavity containing chelating agents and hydrophobic anionic surfactants in the absence of enzymes. The chelating agent may be betaine and the surfactant is preferably a combination of sarcosinate and tartarate. The blend provides a cleaning effect without desequamation of the soft tissues. U.S. Application No. 5,320,831 to Majeti et al., Published June 14, 1994, which relates to oral compositions containing enzymes, surfactants, chelating agents and fluorine ion sources, is also added.

Despite continued interest in this area, there has not yet been produced a stable aqueous dentifrice gel containing baking soda and other natural ingredients with strong cleaning properties.

Summary of the Invention

The main object of the present invention is to provide a stable aqueous skirting agent containing baking soda.

Another object of the present invention relates to a dentifrice containing other natural ingredients with strong cleaning properties.

An advantage of the present invention is that the toothpaste can be formulated as a gel.

Another advantage of the present invention is that the sensitization of the dentifrice is good and encourages regular use.

Still other objects and advantages of the invention are set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. The objects and advantages of the invention can be understood and attained by means and details particularly pointed out in the claims.

In order to achieve the above object embodied and broadly described herein, the present invention provides an aqueous dentifrice comprising a blend of baking soda and natural ingredients.

In addition, to achieve the above object, the present invention provides a method for producing a dentifrice comprising water, baking soda and natural ingredient blends.

The present invention relates to oral hygiene products containing fluoride and baking soda, in particular dentifrices and more specifically gel dentifrices. The present invention also relates to a method for producing and using a dentifrice.

Hereinafter, preferred embodiments of the present invention will be described in detail.

The preparation of dentifrices or gels with a high content of solids, especially baking soda, has generally been a difficult task. This is because a high solid concentration is likely to cause solid-liquid separation or separation. When natural ingredients are formulated in liquid form such as extracts, the problem becomes more difficult.

To overcome this problem, the present invention blends baking soda, natural ingredient blends, flavoring and other dentifrice ingredients to form a stable dentifrice gel.

One of the dentifrice components of the present invention is baking soda, sodium bicarbonate. The dentifrice of the present invention may comprise up to 60% by weight of baking soda. However, it preferably comprises about 35% to about 55% by weight baking soda, more preferably about 40% to about 50% by weight. In the most preferred embodiment of the invention, the dentifrice comprises about 45% by weight baking soda. Although the particle size of the baking soda is not a decisive factor in the present invention, the preferred baking soda is No. 0 to 2% is retained on a 100 standard screen and No. 20 to 45% on 200 standard screens; 60 to 100% retained on a 325 standard screen.

In addition to baking soda, the dentifrice contains various natural ingredients. As used herein, a "natural" component is one that is not essential but is typically extracted or derived from a plant with minimal chemical treatment. Many of such ingredients are commercially available and include, but are not limited to, plant extracts, herbal and flower compresses, and distillates of various materials.

Parodontax Toothpaste of the trademark is one of the preferred combinations of natural ingredients and includes echinacea, myrrh, chamomile, latania and sage.

Echinacea is also known as a juice or extract of cornflower chrysanthemum and is commercially available. This is the dried rhizome and root of Echinacea Pallida and includes inulin, sucrose, betaine and other raw materials.

Myrrh is derived from various species of Commiphora and is a combination of gum, volatile oils and bitter taste components. These are commercially available as extraction components of nonvolatile materials and alcohol solutions.

Camomile is made from dried flower heads of Anthemis nobilis. Their extract ingredients are commercially available and include bitter glucosides, anesterolol, anthemene and volatile oils.

Latania is also known as Krameria and is the dried root of Kramenia triandra and other Kramerian plants. These include chlameriatanic acid and are commercially available as extraction components.

Sage is known as Salvia and is widely known as a flavoring agent. Commercially available, its extract component is derived from dried leaves of Salvia officinalis. 1 to 2.5% of volatile oils, resins, tannins and bitter taste ingredients.

Although any natural ingredient that solid-separates baking baking from the gel is within the scope of the present invention, blends of natural ingredients are preferred. In a preferred embodiment of the invention the natural ingredient blend is Parodontax Combinations of trademark dentifrice natural ingredients, but other natural ingredients may also be included.

In a preferred embodiment, the natural ingredient may comprise up to about 5% by weight of the dentifrice. In a more preferred embodiment, the natural component comprises about 1% to about 4% by weight of the dentifrice. In a more preferred embodiment of the invention, the natural component may comprise from about 2% to about 4% by weight of the dentifrice, and in the most preferred embodiment of the invention may comprise about 3.6% by weight of the dentifrice. In the following examples, the natural ingredients echinacea, myrrh, chamomile, sage and latania make up 3.596% by weight of the dentifrice composition. Those skilled in the art will appreciate that 3.596% by weight is well within the definition of "about 3.6% by weight" as used herein.

In addition to baking soda and other natural ingredients, the dentifrice may include other ingredients used in the dentifrice, including gel skirting agents.

Fluorine sources such as sodium fluoride, tin fluoride, or sodium monofluorophosphate can be used in the dentifrice. Fluorine sources typically comprise less than about 5%, more preferably less than about 2%, and most preferably less than about 1% by weight of the dentifrice.

In addition, the skirting agent of the present invention may include a polishing agent and an abrasive. Examples of such compounds include, but are not limited to, colloidal silicon dioxide and amorphous silica. Such compounds can be used alone or in combination and generally comprise from about 5% to about 15%, preferably from about 6% to about 12%, most preferably about 10% by weight of the dentifrice. .

In addition, dentifrices include sorbitol solutions and humectants such as glycerin. The dentifrice comprises from about 10% to about 40% by weight, preferably from about 20% to about 35% by weight and preferably about 27% by weight of the dentifrice.

In addition, the dentifrice may contain a binder such as xanthan gum and a sweetener such as sodium saccharin. The binder generally comprises less than about 1% by weight of the dentifrice, and the sweetener can adjust the taste.

One of the advantages of the present invention is that it is possible to incorporate a moderately large amount of flavor into the dentifrice. As long as the flavoring agent is a "natural" component as described above, the primary purpose of such raw materials in dentifrices is to impart good flavor to the toothpaste. Typically flavoring agents include various mint flavoring agents such as spearmint and peppermint. However, the present invention is not limited to toothpaste flavored with mint. Although the flavourant, preferably constitutes up to about 3% by weight of the dentifrice composition, more preferably up to about 2% by weight, the flavour comprises up to about 5% by weight of the dentifrice.

The dentifrice may also contain other known ingredients used in the dentifrice, including bleach, tartar and desensitizing agents.

Unexpectedly, the composition prepared according to the present invention appeared to be stable. Without wishing to be bound by any theory, it appears that the components and / or methods of processing the components combine to make the product physically stable.

The dentifrice of the present invention is prepared essentially by the method shown in Example 1. Water soluble salts, ie fluorides and sweeteners, are mixed in water. A moisturizer is then added and a binder is also added. Natural ingredients are added, followed by abrasives, cleaners and baking soda. Finally, flavor oil, more detergent and additional natural raw materials are added.

The following examples are merely intended to illustrate some features and advantages of the present invention and are not intended to limit the scope of the claims.

Example 1

274 kg of water was charged to the mixing tank to prepare a 3,000 kg batch of dentifrice according to the present invention. 1.5 kg sodium saccharin and 9.4 kg sodium fluoride were added and stirred until dissolved. With continuous stirring, 300 kg of glycerin and 510 g of sorbitol were added to the tank, and 15 kg of xanthan gum was added slowly with high shear stress for 30 minutes. 18.7 g Myrrh extract component, 18.7 g Camomile extract component and 28.5 kg Echinacea were slowly added to the tank. 24 kg of colloidal silicon dioxide were added with high shear stress mixed, followed by 300 kg of amorphous silica. Sodium sarcosinate (30 kg) is added, followed by 700 kg of sodium bicarbonate, 6 kg of coco-amidopropyl betaine, another 650 kg of sodium bicarbonate, 57.8 kg of peppermint oil, 15 kg of lysolexine, 4.38 kg of sage oil and 37.44 kg of Latania extract were added. The whole product was thoroughly mixed and placed in a suitable tube, and the composition of the dentifrice is shown in Table 1.

A portion of the composition of Example 1 was filled in a 25 ml dentifrice tube and subjected to a standard freeze / thaw test. The results are shown in Table 2. In addition, the sample was tested for stability at 40 ° C. for 4 months, and the results are shown in Table 3. "NR" in Tables 2 and 3 means that nothing was measured. "Pass" means that the properties tested meet the designed product specifications. In appearance and container integrity, there were no obvious drawbacks in the design specification. In Munsell color, the specifications were 7.5R 2/4 and 7.5R 6/6.

Examples 2 and 3

The composition shown in Table 1 was prepared using the method shown in Example 1. A portion of this composition was filled into 25 ml dentifrice tubes and subjected to the freeze / thaw test and stability test. The results are shown in Table 3. Example 3 was not tested for stability at 40 ° C.

Dentifrice composition Raw material Example 1 wt% Example 2 wt% Example 3 wt% water 9.118 8.298 13.218 Sodium fluoride 0.31 0.23 0.31 Sodium saccharin 0.05 0.05 0.05 Juice squeezed from cornflower-stabilized 0.954 0.954 0.954 Myrrh Extract Ingredients 0.624 0.624 0.624 Camomile Extract Ingredients 0.624 0.624 0.624 Latania Extract Ingredients 1.248 1.248 1.248 Sorbitol solution 70% 17 17 17 Colloidal silicon dioxide 0.8 1.7 1.7 Amorphous silica 10 10 5 Glycerin 96% 10 10 10 Xanthan gum 0.5 0.5 0.5 Cocoamidopropyl betaine 0.2 0.2 0.2 Sodium Lauryl Sarcosinate One One One Lysolectin 0.5 0.5 0.5 Sodium bicarbonate 45 45 45 Sage oil 0.146 0.146 0.146 Peppermint Oil 1.926 1.926 1.926 sum 100.000 100.000 100.000

Freeze / Thaw Data Tested characteristics Duration, 0 days 5 days 9th example: 3-10 days 14 days ocean 1: Pass 1: Pass 1: Pass 1: Pass 2: Pass 2: Pass 2: Pass 2: Pass 3: pass 3: pass 3: pass 3: pass Munsell color 1: Pass 1: Pass 1: Pass 1: Pass 2: Pass 2: Pass 2: Pass 2: Pass 3: pass 3: pass 3: pass 3: pass pH 2: 8.76 2: 8.72 1: 8.2 1: 8.2 3: 8.71 3: 8.40 2: 8.10 2: 8.29 1: 1.56 1: 1.58 3: 8.59 3: 8.47 Viscosity (x 103) cps 2: 1.76 2: 3.00 1: 1.72 1: 2.00 3: 1.40 3: 1.24 2: 3.80 2: 5.20 1: 1358 1: NR 3: 2.40 3: 1.80 Fluorine Ion (ppm) 2: 1063 2: NR 1: NR 1: 1282 2: NR 1: 1022 3: 1501 3: NR 3: NR 1: 1433 Sodium bicarbonate (% by weight) 1: 46% 1: NR 1: NR 1: 45% 2: 46.4% 2: NR 2: NR 1: 46.1% 3: 46.7% 3: NR 3: NR 1: 46.3% Container integrity 1: Pass 1: NR 1: NR 1: Pass 2: Pass 2: Pass 2: Pass 2: Pass 3: pass 3: pass 3: pass 3: pass

Safety test Tested characteristics Duration, 0 months 1 month 3 months 4 months ocean 1: Pass 1: Pass 1: Pass 1: Pass 2: Pass 2: NR 2: Pass 2: Pass Munsell color 1: Pass 1: NR 1: NR 1: NR 2: Pass 2: NR 2: Pass 2: Pass pH 1: 8.3 2: 8.8 1: 8.4 1: 8.2 2: 8.76 3: NR 2: 8.18 2: 8.71 Viscosity (x 103) cps 1: 1.56 2: 1.98 1: 2.44 1: 3.00 2: 1.78 3: NR 2: 6.30 2: 7.75 Ionic Fluoride (ppm) 1: 1358 2: 1344 1: 1346 1: 1368 2: 1063 3: NR 3: 1000 1: 1042 Sodium bicarbonate (% by weight) 1: 46% 1: 46% 1: 47% 1: 48% 2: 46.4% 2: NR 2: 47.7% 1: 47% Courage preservation 1: Pass 1: Pass 1: Pass 1: Pass 2: Pass 2: NR 2: Pass 2: Pass

The purpose of the above description is to illustrate some embodiments of the invention without limitation. Those skilled in the art will readily appreciate that various modifications and changes can be made in the apparatus or process of the invention without departing from the scope or spirit of the invention.

Claims (19)

(a) sodium bicarbonate; (b) natural ingredient blends; And (c) flavoring agents Oral hygiene composition comprising a. 2. The oral care composition of claim 1, wherein said natural ingredient blend contains at least one component selected from the group consisting of echinacea, myrrh, chamomile, latania and sage. (a) sodium bicarbonate; (b) natural ingredient blends; And (c) flavoring agents Skirting agent including. The dentifrice of claim 3 wherein the sodium bicarbonate constitutes up to about 60% by weight. The dentifrice of claim 4 wherein sodium bicarbonate comprises about 35% by weight. 6. The dentifrice of claim 5 wherein sodium bicarbonate comprises about 40 wt% to 50 wt%. The dentifrice of claim 6 wherein sodium bicarbonate comprises about 45% by weight. 4. The dentifrice of claim 3 wherein said natural ingredient blend comprises one or more ingredients selected from the group consisting of echinacea, myrrh, chamomile, latania and sage. The dentifrice of claim 8 wherein said natural ingredient blend constitutes at most about 5% by weight. 10. The dentifrice of claim 9 wherein said natural ingredient blend comprises about 1% to about 4% by weight. The dentifrice of claim 10 wherein said natural ingredient blend comprises about 2% to 4% by weight. 12. The dentifrice of claim 11 wherein said natural ingredient blend comprises about 3.6% by weight. 4. The dentifrice of claim 3 further comprising a fluoride source. The dentifrice of claim 13, further comprising at least one abrasive polish, at least one moisturizer, at least one binder, at least one sweetener, and water. (a) up to about 60 weight percent sodium bicarbonate; (b) up to about 5 weight percent of a natural ingredient blend; And (c) up to about 2 percent by weight flavor Skirt gel containing a. The method of claim 15, (d) less than about 5 weight percent fluoride source; (e) up to about 5 weight percent of one or more surfactants; (f) about 5% to about 15% by weight of one or more abrasive polishes; (g) about 10 wt% to about 40 wt% humectant; And (h) less than 1% by weight of binder Schizogel gel further comprising. (a) about 45 weight percent sodium bicarbonate; (b) about 3.6% by weight natural ingredient blend; (c) about 5% flavoring agent; (d) less than about 1 weight percent fluoride source; (e) up to about 3 weight percent of one or more surfactants; (f) about 10 weight percent abrasive polish; (g) about 27% wetting agent; (h) less than 1 wt% binder; (i) less than about 1 weight percent sweetener; And (j) water Skirt gel containing a. (a) mixing the sweetener and the fluoride source in water to produce a primary mixture; (b) adding at least one moisturizer to the primary mixture; (c) adding at least one natural component, a binder and at least one abrasive polish to the primary mixture to form a secondary mixture; (d) combining sodium bicarbonate, at least one surfactant, a flavourant and at least one additional natural ingredient to the secondary mixture to form a dentifrice Manufacturing method of the skirting agent containing. The method of claim 18, wherein the dentifrice is a gel.