KR102621129B1 - Natural cosmetic composition using grains and herbal medicines - Google Patents
Natural cosmetic composition using grains and herbal medicines Download PDFInfo
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- KR102621129B1 KR102621129B1 KR1020230035834A KR20230035834A KR102621129B1 KR 102621129 B1 KR102621129 B1 KR 102621129B1 KR 1020230035834 A KR1020230035834 A KR 1020230035834A KR 20230035834 A KR20230035834 A KR 20230035834A KR 102621129 B1 KR102621129 B1 KR 102621129B1
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Abstract
Description
본 발명은 곡물 및 한약재를 이용한 천연 화장료 조성물에 관한 것으로, 피부 노화 방지 및 주름 개선 효능을 가지고 있으며, 피부 미백 및 수분 보습 효능이 우수하고, 화농성 여드름을 개선하는 다양한 효과를 가진 천연 화장료 조성물 및 이의 제조방법에 관한 것이다. The present invention relates to a natural cosmetic composition using grains and herbal medicine, which has anti-aging and wrinkle-improving effects, has excellent skin whitening and moisturizing effects, and has various effects in improving purulent acne, and natural cosmetic compositions thereof. It is about manufacturing method.
인체의 피부는 자외선이나 다양한 오염 및 공해물질이나, 온도 및 습도의 변화 등과 같은 피부에 유해한 외부환경 자극으로부터 인체를 보호해 주는 일차 배리어(barrier)로서의 기능을 수행한다. 피부는 표피, 진피 및 피하조직의 3개 층으로 구분되며, 표피는 다시 각질층, 과립층, 유극층 및 기저층으로 분류되고, 각질층은 외관상으로 드러나게 되는 최외곽층으로서 유해한 외부 환경에 대한 물리 화학적 저항력을 나타내며 미용학적으로 매우 중요하다. The human skin functions as a primary barrier that protects the human body from external environmental stimuli harmful to the skin, such as ultraviolet rays, various pollution and pollutants, and changes in temperature and humidity. The skin is divided into three layers: the epidermis, dermis, and subcutaneous tissue. The epidermis is further divided into the stratum corneum, stratum granulosum, stratum spinosum, and basal layer. The stratum corneum is the outermost layer that is visible and provides physical and chemical resistance to harmful external environments. It is very important cosmetically.
인간의 표피는 외측으로부터 "각질층(각층)", "과립층", "유극층", "기저층"으로 구성되며, 기저 층에서 생겨난 표피 세포(케라티노사이트)가 순차적으로 외측으로 이동하여 각질층이 되고, 결국에는 벗겨져 떨어지게 된다. 보다 상세하게는 케라티노사이트가 표피의 가장 안쪽에 있는 기저층에서 증식하고 분화하여 상층으로 밀어 올려지며, 최종적으로 표피의 가장 외측에 위치하는 각질층(각층)이 되고, 때가 되어 탈락하게 된다. 이 케라티노사이트의 증식, 이동, 분화, 탈락의 일련의 과정을 턴오버라고 하며, 케라티노사이트가 일정 주기로 새롭게 생성되어 변해감으로써 피부의 항상성이 유지되고 있는데, 나이 듦에 따라 피부의 턴오버(turn-over) 속도가 느려지고, 그 결과, 주름이나 처짐이나 피부 거침이 생긴다고 한다.The human epidermis is composed of the “stratum corneum”, “stratum granulosum”, “layer spinosum”, and “basal layer” from the outside, and epidermal cells (keratinocytes) generated in the basal layer sequentially move outward to become the stratum corneum. , it will eventually peel off and fall off. More specifically, keratinocytes proliferate and differentiate in the basal layer, the innermost layer of the epidermis, and are pushed up to the upper layer, ultimately becoming the stratum corneum (stratum corneum), located on the outermost layer of the epidermis, before falling off in due course. This series of processes of proliferation, movement, differentiation, and shedding of keratinocytes is called turnover, and skin homeostasis is maintained as keratinocytes are newly produced and changed at regular intervals. As skin ages, turnover occurs. It is said that the (turn-over) speed slows down, resulting in wrinkles, sagging, and rough skin.
피부는 다양한 외부자극(화학물질, 대기오염물질, 건조한 환경, 자외선 등)에 대한 방어와 피부를 통한 체내 수분의 과도한 발산을 막는 장벽기능을 가지고 있으며, 이러한 장벽기능은 각질형성세포로 구성된 각질층이 정상적으로 형성되어 있을 경우에만 그 기능을 유지할 수 있다. 또한, 각질형성세포는 표피의 최하층에서 지속적으로 증식하는 기저세포가 단계적으로 형태 및 기능상의 변화를 거쳐 수분을 함유하면서 얇은 각질층으로 발달하는 특징적인 세포이며, 일정 기간이 경과하면 오래된 각질세포는 피부에서 탈락되고 새로운 각질세포가 그 기능을 대신하는 각화과정을 반복적으로 거친다.The skin has a barrier function that protects against various external stimuli (chemicals, air pollutants, dry environment, ultraviolet rays, etc.) and prevents excessive dissipation of body moisture through the skin. This barrier function is achieved by the stratum corneum composed of keratinocytes. It can maintain its function only if it is formed normally. In addition, keratinocytes are characteristic cells in which basal cells that continuously proliferate in the lowest layer of the epidermis gradually undergo changes in form and function and develop into a thin keratin layer while containing water. After a certain period of time, old keratinocytes become part of the skin. It goes through the keratinization process repeatedly, where it falls off and new keratinocytes take over its function.
이러한 각질층은 생활 습관적 요인(과도한 세안, 목욕)이나 환경적인 요인(건조한 대기 오염 물질) 및 내인성 질환(아토피성 피부, 노인성 피부) 등에 의해 그 기능이 소실될 수 있다. 특히 일상 생활 중에 화장료 또는 오염을 제거하기 위해 비누를 사용하는 과정에서 피부의 수분이 빠져나가 당기는 느낌을 받게 되는데 이는 일반적인 비누의 경우 세정과정에서 피부장벽에 수분이 손실되어 피부 보습력이 저하되는 것에 기인한 것이다. 이는 피부주름을 높일 뿐 아니라 지속적으로 비누 세정에 의한 피부 보습력 저하의 경우 각종 피부질환의 원인이 될 수 있다.This stratum corneum can lose its function due to lifestyle factors (excessive washing, bathing), environmental factors (dry air pollutants), and endogenous diseases (atopic skin, senile skin). In particular, in the process of using soap to remove cosmetics or contamination during daily life, moisture from the skin is lost and a tight feeling is felt. This is due to the loss of moisture in the skin barrier during the washing process in the case of general soap, which reduces the skin's moisturizing ability. It was done. This not only increases skin wrinkles, but can also cause various skin diseases if the skin's moisturizing ability decreases due to continuous soap washing.
이에, 우수한 세정효과와 함께 피부자극 및 건조에 의한 주름생성을 억제할 수 있는 천연 세정제에 대한 수요가 높아지고 있으며, 최근 다양한 천연물 및 첨가물이 포함되어 다양한 기능을 낼 수 있도록 하는 기능성 비누 등이 개발되고 있다. 그러나, 이들 비누들은 천연물의 부작용이 발생하여 소량으로 사용할 수밖에 없거나 피부 보습 효과 또는 피부미백 개선 효과가 미미하여 일반적인 기능추가에 그치고 있으며 실질적으로 피부 개선에 탁월한 효과를 갖는 제품은 거의 없는 실정이다. Accordingly, the demand for natural cleansers that have excellent cleaning effects and can suppress wrinkles caused by skin irritation and dryness is increasing. Recently, functional soaps containing various natural products and additives that provide various functions have been developed. there is. However, these soaps have side effects from natural products, so they can only be used in small quantities, or their skin moisturizing effect or skin whitening improvement effect is minimal, so they are limited to adding general functions, and there are virtually no products that have an excellent effect on improving the skin.
따라서 본 발명자는 상기와 같은 문제점을 해결할 수 있는 새로운 천연 화장료 조성물 및 그 제조 방법을 개발하고자 하였다.Therefore, the present inventor sought to develop a new natural cosmetic composition and a method for producing the same that can solve the above problems.
상기와 같은 문제점을 해결하기 위한 본 발명의 목적은 현미, 기장, 서리태 등 12종의 곡물 혼합물;과 오미자, 녹용, 백복령 등의 31종의 한약재 혼합 추출물; 피마자씨 오일, 팜열매 오일 등 9종의 오일 혼합물;을 특유의 비율로 혼합하여 제조하는 복합 피부 개선용 화장료 조성물을 제공하는 것이다. The purpose of the present invention to solve the above problems is a mixture of 12 types of grains such as brown rice, millet, and Seoritae; and a mixture of extracts of 31 types of herbal medicines such as Schisandra chinensis, deer antler, and Baekbokryeong; The present invention provides a complex skin improvement cosmetic composition prepared by mixing a mixture of nine types of oils, such as castor seed oil and palm fruit oil, in a unique ratio.
상기와 같은 목적을 달성하기 위한 본 발명의 일 측면은 곡물가루 혼합물, 한약재 혼합 추출물 및 오일 혼합물을 포함하는 피부 개선용 화장료 조성물로서, 상기 곡물가루 혼합물은 현미, 기장, 서리태, 율무, 귀리, 보리, 수수, 팥, 녹두, 흑미, 좁쌀의 곡물 10종과 산자나무 열매 및 키위를 포함하여 총 12종의 식물을 건조 후 분말화 하여 혼합한 것이고, 상기 한약재 혼합 추출물은 오미자, 녹용, 백복령, 솔잎, 백작약, 인삼, 산수유, 황기, 뽕잎, 황기, 구기자, 녹차, 감초를 포함하는 제1 한약재 혼합물; 백지, 백급, 백렴, 백강잠, 백부자, 천화분, 감송향, 삼내자, 곽향, 영릉향, 방풍, 고본을 포함하는 제2한약재 혼합물; 및 조각자, 생지황, 황금, 황백, 치자, 백수오를 포함하는 제3 한약재 혼합물;을 포함하여 제조되는 것이며, 상기 오일 혼합물은 팜열매 오일, 쌀겨 오일, 피마자씨 오일, 해바라기씨 오일, 라벤더 오일, 시어버터, 올리브오일, 코코넛야자오일, 포도씨오일의 9종을 포함하여 제조되는 것이다. One aspect of the present invention for achieving the above object is a cosmetic composition for skin improvement comprising a grain powder mixture, a mixed extract of herbal medicine, and an oil mixture, wherein the grain powder mixture includes brown rice, millet, seaweed, coix seed, oats, and barley. , a total of 12 types of plants, including 10 types of grains such as sorghum, red beans, mung beans, black rice, and millet, and sea buckthorn fruit and kiwi, are dried, powdered, and mixed, and the herbal medicine mixed extract is Schisandra chinensis, antler, white bokryeong, and pine needles. , a first herbal medicine mixture containing white peony, ginseng, Cornus officinalis, astragalus, mulberry leaf, astragalus, goji berry, green tea, and licorice; A second herbal medicine mixture including Baekji, Baekgeup, Baekryeom, Baekganjam, Baekbuja, Cheonhwabun, Spikenth, Samnaeja, Kwakhyang, Yeongneunghyang, Bangpung, and Gobon; And a third herbal medicine mixture containing Scallop, Saenghwang, Golden, Hwangbaek, Gardenia, Baeksoo, and the oil mixture is palm fruit oil, rice bran oil, castor seed oil, sunflower seed oil, lavender oil, and shea. It is manufactured including 9 types of butter, olive oil, coconut palm oil, and grape seed oil.
구체적으로, 상기 곡물가루 혼합물은 현미, 율무, 팥 등의 곡물 10종과 2종의 열매를 혼합하고 분쇄하고 건조하여 가루로 만든 것으로 피부에 영양과 수분을 공급하고 각질과 노폐물을 부드럽게 제거하는 역할을 한다.Specifically, the grain powder mixture is made by mixing, pulverizing, drying, and powdering 10 types of grains such as brown rice, coix seed, and red beans, and 2 types of fruits, and serves to provide nutrition and moisture to the skin and gently remove dead skin cells and waste. Do it.
각 성분에 대해 더욱 구체적으로 살펴보면, 현미는 비타민 B1과 B2가 풍부하여 피부 탄력을 증진하고 색소침착을 방지하는 것으로 알려져 있고, 기장은 식이섬유와 칼슘이 많아 장 건강을 돕고 피부에 수분과 영양을 공급하는 것으로 알려져 있다. 서리태는 아미노산과 미네랄이 많아 피부 재생을 돕고 항염 및 항산화 작용을 할 수 있으며, 율무는 비타민 E와 셀레늄이 많아 피부 노화를 예방하고 멜라닌 생성을 억제하는 것으로 알려져 있다. 또한, 귀리(오트밀)는 베타글루칸이라는 성분을 포함하여 각질 제거와 보습에 좋으며 염증성 질환에도 도움이 되고, 보리는 실리카라는 성분이 콜라겐 생성을 촉진하고 모공을 축소시키는 것으로 알려져 있다. 수수는 당질과 단백질이 많아 피부 탄력과 윤기를 높여줄 수 있으며, 팥은 철분과 비타민 B1이 많아 혈액순환을 돕고 주근깨나 여드름 등의 발생을 줄여줄 수 있다. 녹두는 비타민 A와 C가 많아 각질 제거와 미백에 좋으며, 흑미는 안토시아닌이라는 성분이 항산화 작용을 하며 멜라닌 생성을 억제하여 미백에 도움을 줄 수 있고, 좁쌀은 철분과 엽산이 풍부하여 피부 건강에 도움을 줄 수 있을 뿐 아니라 식물성 단백질이 많이 함유되어 피부 탄력과 수분을 증가시킬 수 있다.Looking at each ingredient in more detail, brown rice is rich in vitamins B1 and B2, which are known to improve skin elasticity and prevent pigmentation, while millet is rich in dietary fiber and calcium, which helps maintain intestinal health and provides moisture and nutrition to the skin. It is known to supply Seoritae is rich in amino acids and minerals, so it helps skin regeneration and has anti-inflammatory and antioxidant properties. Coix radish is rich in vitamin E and selenium, so it is known to prevent skin aging and suppress melanin production. In addition, oats (oatmeal) contain a component called beta-glucan, which is good for exfoliating and moisturizing, and is helpful for inflammatory diseases, while barley contains a component called silica, which is known to promote collagen production and shrink pores. Sorghum is high in sugar and protein, which can increase skin elasticity and gloss, and red beans are high in iron and vitamin B1, which can help blood circulation and reduce the occurrence of freckles and acne. Mung beans are high in vitamins A and C, which are good for exfoliation and whitening. Black rice contains anthocyanin, which has an antioxidant effect and can help whiten by suppressing melanin production. Millet rice is rich in iron and folic acid, which helps keep skin healthy. Not only does it contain a lot of vegetable protein, it can increase skin elasticity and moisture.
본 발명에서 산자나무열매(Hippophae rhamnoides L)는 보리수과에 속하는 관목으로서 100여종 이상의 성분을 포함하고 있으며, 특히 비타민(A, B, C, E, F, K) 등 유효한 성분을 많이 함유하고 있다. 항산화 물질인 카로티노이드의 베타카로틴, 플라보노이드 성분이 풍부하게 들어있어 강력한 항산화 작용을 하는 것으로 알려져 있다. 키위는 비타민 C가 다수 함유되어 콜라겐 합성을 돕고, 피부 손상을 개선할 수 있으며, 비타민 E와 폴리페놀이 함유되어 잔주름을 줄이고, 노화를 방지할 수 있는 것으로 알려져 있다.In the present invention, sea buckthorn fruit ( Hippophae rhamnoides L ) is a shrub belonging to the linden family and contains more than 100 kinds of ingredients, especially vitamins (A, B, C, E, F, K) and other effective ingredients. It is known to have a strong antioxidant effect as it is rich in beta-carotene and flavonoids, which are antioxidant carotenoids. Kiwi is known to contain a lot of vitamin C, which helps collagen synthesis and improve skin damage, and it contains vitamin E and polyphenol, which can reduce fine wrinkles and prevent aging.
한편, 상기 한약재 혼합 추출물은 31종의 한약재를 이용하여 제조한 것으로서, 피부 진정과 보습, 항산화와 항염 등의 다양한 효능을 가지고 있다.Meanwhile, the herbal medicine mixed extract is manufactured using 31 types of herbal medicine, and has various effects such as skin soothing and moisturizing, antioxidant and anti-inflammatory properties.
구체적으로, 상기 제1한약재 혼합물은 13종의 한약재인 오미자, 녹용, 백복령, 솔잎, 백작약, 인삼, 산수유, 황기, 뽕잎, 황기, 구기자, 녹차, 감초가 혼합된 것으로서, 녹용을 제외한 나머지 12종의 한약재는 동일한 중량으로 포함되며, 녹용은 오미자 중량의 0.1 중량부가 되도록 혼합하였다. 오미자는 5가지 맛이 나는 식물로 폐와 간의 기능을 개선하고 정력과 피로를 회복하는 효능이 있다. 녹용은 체액을 보충하고 원기를 회복하는 보양제로 쇠약과 피로에 좋다. 백복령은 비염과 알레르기에 도움이 되는 항염제로 사용될 수 있다. 솔잎은 가래와 염증을 완화하고 면역력을 강화하는 효능이 있다. 백작약은 혈액 순환을 돕고 빈혈과 월경불순에 좋다. 인삼은 기운을 북돋우고 신경계와 호흡계를 안정시키는 효능이 있다. 산수유는 비타민C가 풍부하여 면역력과 항산화 작용을 한다. 황기는 위장 기능을 강화하고 당뇨와 관절염에 도움이 되는 효능이 있다. 뽕잎은 혈관 건강과 혈당 조절에 도움이 되는 효능이 있다. 구기자는 안색을 개선하고 심혈관 질환 예방에 도움이 되는 효능이 있다. 녹차는 치아 건강과 다이어트에 도움이 되는 항산화 성분이 들어있다. 감초는 염증과 감염을 억제하고 해독 작용을 하는 효능이 있다.Specifically, the first herbal medicine mixture is a mixture of 13 kinds of herbal medicines, Schisandra chinensis, deer antler, Baekbokryeong, pine needles, peony peony, ginseng, Cornus officinalis, astragalus, mulberry leaf, astragalus, goji berry, green tea, and licorice. Excluding deer antler, the remaining 12 kinds. Herbal medicines were included in the same weight, and deer antler was mixed in an amount of 0.1 part by weight based on the weight of Schisandra chinensis. Schisandra chinensis is a plant that comes in five flavors and has the effect of improving lung and liver function and restoring energy and fatigue. Antler is an aphrodisiac that replenishes body fluids and restores vitality, and is good for weakness and fatigue. Baekbokryeong can be used as an anti-inflammatory to help with rhinitis and allergies. Pine needles have the effect of relieving phlegm and inflammation and strengthening immunity. White peony helps blood circulation and is good for anemia and menstrual irregularities. Ginseng has the effect of boosting energy and stabilizing the nervous and respiratory systems. Cornus officinalis is rich in vitamin C, which boosts immunity and acts as an antioxidant. Astragalus has the effect of strengthening gastrointestinal function and helping with diabetes and arthritis. Mulberry leaves have beneficial effects on blood vessel health and blood sugar control. Goji berry has the effect of improving complexion and helping prevent cardiovascular disease. Green tea contains antioxidants that are helpful for dental health and diet. Licorice has the effect of suppressing inflammation and infection and detoxifying.
상기 제2한약재 혼합물은 12종의 한약재인 백지, 백급, 백렴, 백강잠, 백부자, 천화분, 감송향, 삼내자, 곽향, 영릉향, 방풍, 고본이 혼합된 것으로서, 백지, 백급, 백렴, 백강잠, 백부자, 천화분은 모두 피부 미백에 도움이 되는 한약재로 알려져 있으나, 나머지 한약재와 다같이 함께 사용된 예는 알려진 바 없다. 본 제2한약재 혼합물의 한약재는 모두 동일 중량으로 혼합하여 제조하였다. 구체적으로, 백지(白芷), 백급(白), 백렴(白蓮), 백강잠(白降丹), 백부자(白茯), 천화분(千花粉)은 모두 피부 미백에 효과적인 한약재이다. 이들은 피부 색소인 멜라닌의 합성과 침착을 억제하고 피부 세포의 재생을 촉진하여 기미와 주근깨를 예방하고 개선한다. 감송향, 삼내자, 곽향, 영릉향은 피부에 좋은 약재로 알려져 있다. 이들은 피부의 혈액 순환을 돕고 염증을 완화하여 여드름과 뾰루지를 치료하고 피부 건강을 유지한다. 방풍과 고본은 피부에 좋은 해열제와 진해제이다. 이들은 열기와 습기를 제거하고 독소를 배출하여 피부 발진과 가려움증을 줄이고 피부를 맑게 한다.The second herbal medicine mixture is a mixture of 12 kinds of herbal medicine, Baekji, Baekgeup, Baekryeom, Baekgangjam, Baekbuja, Cheonhwabun, Gamsonhyang, Samnaeja, Gwakhyang, Yeongneunghyang, Bangpung, and Gobon. Baekbuja and Cheonhwabun are all known as herbal medicines that help whiten the skin, but there are no known examples of them being used together with the rest of the herbal medicines. All the herbal medicines in this second herbal medicine mixture were prepared by mixing them at the same weight. Specifically, Baekji(白芷), Baekgeup(白), Baekryeom(白蓮), Baekgangjam(白降丹), Baekbuja(白茯), and Cheonhwabun(千花粉) are all effective herbal medicines for skin whitening. They inhibit the synthesis and deposition of melanin, a skin pigment, and promote the regeneration of skin cells to prevent and improve spots and freckles. Gamsonhyang, Samnaeja, Gwakhyang, and Yeongneunghyang are known as medicinal herbs that are good for the skin. They help with blood circulation in the skin and relieve inflammation, treating acne and pimples and maintaining skin health. Bangpung and Gobon are antipyretics and cough relievers that are good for the skin. They remove heat and moisture and expel toxins, reducing skin rashes and itching and clearing the skin.
상기 제3한약재 혼합물은 6종의 한약재인 조각자, 생지황, 황금, 황백, 치자, 백수오로 이루어져 있으며, 이들의 혼합 비율은 2:2:1:2:2:1의 중량비가 되도록 혼합하였다. 조각자는 피부 손상 치료 및 염증 감소에 기여하는 것으로 알려져 있으며, 이는 피부 장벽 회복에 도움을 줄 수 있다. 생지황은 피부 탄력 증진과 주름 개선에 효과적인 성분으로, 콜라겐 생성을 촉진함으로써 피부 노화 방지에 기여한다. 황금은 피부 톤 개선과 미백 효과를 제공하여, 멜라닌 생성을 억제하고 기미와 주근깨를 줄이는 데 도움이 된다. 황백은 피부 진정 효과를 가지고 있어, 피부의 붉은 기와 자극을 완화하며, 피부 장벽 강화에 기여한다. 치자는 피부 보습 작용을 가지고 있어, 건조한 피부에 수분을 공급하고 유지함으로써 촉촉한 피부를 유지하도록 돕는다. 백수오는 각질 제거와 피부 재생을 촉진하는 성분으로, 매끄러운 피부결 형성을 도와줄 수 있다.The third herbal medicine mixture consists of six kinds of herbal medicines, Scallopia, Saenghwang, Golden, Hwangbaek, Gardenia, and Baeksoo, and their mixing ratio was mixed to a weight ratio of 2:2:1:2:2:1. Sculptor is known to help heal skin damage and reduce inflammation, which can help restore the skin barrier. Raw Rehmannia glutinosa is an effective ingredient in improving skin elasticity and improving wrinkles, and contributes to preventing skin aging by promoting collagen production. Gold improves skin tone and provides a whitening effect, helping to suppress melanin production and reduce dark spots and freckles. Yellow-white has a skin-soothing effect, relieves skin redness and irritation, and contributes to strengthening the skin barrier. Gardenia has a skin moisturizing effect, helping to maintain moist skin by supplying and maintaining moisture in dry skin. Baeksoo is an ingredient that removes dead skin cells and promotes skin regeneration, and can help form a smooth skin texture.
상기 제1 내지 3 한약재 혼합물은 필요에 따라 혼합 비율을 달리 할 수 있으나, 본 발명의 천연 화장료 조성물이 가지는 여러 복합적인 효과로서 주름개선, 미백, 기미 개선 및 여드름 완화의 효과를 보기 위해서는 제1, 2, 3 한약재 혼합물이 순서대로 각각 1:3:1의 비율로 혼합되는 것이 가장 효과가 좋으며, 피부보습 효과를 개선하기 원하면 제3한약재 혼합물의 비율을 2배가량 높여 적용하는 것도 가능하다.The mixing ratio of the first to third herbal medicine mixtures may be varied as needed, but in order to see the various complex effects of the natural cosmetic composition of the present invention, such as wrinkle improvement, whitening, dark spot improvement, and acne relief, the first to third herbal medicine mixtures may be mixed as needed. It is most effective to mix the 2nd and 3rd herbal medicine mixture in order at a ratio of 1:3:1, respectively. If you want to improve the skin moisturizing effect, it is also possible to double the ratio of the third herbal medicine mixture.
본 발명의 한약재를 추출하는 방법은 특별히 제한되지 아니하며, 당해 기술 분야에서 통상적으로 사용하는 방법에 따라 추출할 수 있다. 상기 추출 방법의 비제한적인 예로는, 열수 추출법, 초음파 추출법, 여과법, 환류 추출법 등을 들 수 있으며, 이들은 단독으로 수행되거나 2 종 이상의 방법을 병용하여 수행될 수 있다. The method for extracting the herbal medicine of the present invention is not particularly limited, and can be extracted according to a method commonly used in the art. Non-limiting examples of the extraction method include hot water extraction, ultrasonic extraction, filtration, and reflux extraction, which may be performed alone or by combining two or more methods.
본 발명에서 사용되는 추출용매의 종류는 특별히 제한되지 아니하며, 당해 기술 분야에서 공지된 임의의 용매를 사용할 수 있다. 상기 추출 용매의 비제한적인 예로는 물(정제수), C1 내지 C4의 무수 또는 저급 알코올, 상기 물과 저급 알코올의 혼합 용매, 아세톤, 1,3-부틸렌글리콜, 에틸아세테이트, 클로로포름으로 이루어진 군에서 선택되는 1 종 이상으로, 단독으로 2종 이상 혼합하여 사용할 수 있다. The type of extraction solvent used in the present invention is not particularly limited, and any solvent known in the art can be used. Non-limiting examples of the extraction solvent include water (purified water), C 1 to C 4 anhydrous or lower alcohol, a mixed solvent of water and lower alcohol, acetone, 1,3-butylene glycol, ethyl acetate, and chloroform. One or more types selected from the group can be used individually or in mixture of two or more types.
본 발명에서는 상기 한약재를 100℃의 정제수를 이용하여 4내지 6시간동안 열수 추출하고, 이를 감압 농축하여 본 발명의 한약재 혼합 추출물을 수득하였으나, 이에 제한되는 것은 아니다.In the present invention, the herbal medicine mixed extract of the present invention was obtained by hot-water extraction of the herbal medicine using purified water at 100°C for 4 to 6 hours and concentration under reduced pressure, but the extract is not limited thereto.
본 발명에서 상기 오일혼합물은 올리브 오일 및 쌀겨 오일 등의 식물성 오일로 구성되는 것으로서, 피부장벽을 강화하고 유수분 밸런스를 조절하는 역할을 한다. 구체적으로, 본 발명에서는 팜열매 오일, 쌀겨 오일, 피마자씨 오일, 해바라기씨 오일, 라벤더 오일, 시어버터, 올리브오일, 코코넛야자오일, 포도씨오일을 동일한 비율로 혼합한 오일 혼합물을 사용하였다. 상기 팜열매 오일은 피부 장벽 강화와 수분 보존 능력 향상에 도움을 주는 성분으로 작용한다. 쌀겨 오일은 항산화 성분이 풍부하여 피부 노화 방지와 피부톤 개선에 기여한다. 피마자씨 오일은 오메가-3 지방산의 고함량으로 인해 피부의 탄력 개선과 진정 효과를 제공한다. 해바라기씨 오일은 비타민 E의 농도가 높아 피부 항산화 작용을 지원하며, 자극받은 피부에 진정 효과를 가져온다. 라벤더 오일은 진정 효과가 우수하여 여드름이나 트러블 피부에 도움을 준다. 시어버터는 수분 잠금 능력이 뛰어나 건조한 피부에 적합하다. 올리브오일은 피부 보습 및 부드러움 증진에 효과적이다. 코코넛야자오일은 피부에 깊은 영양과 보습 효과를 제공한다. 포도씨 오일은 항산화 성분이 풍부하여 피부 노화 예방 및 유연성 증진에 도움을 줄 수 있다.In the present invention, the oil mixture is composed of vegetable oils such as olive oil and rice bran oil, and serves to strengthen the skin barrier and regulate oil and water balance. Specifically, in the present invention, an oil mixture of palm fruit oil, rice bran oil, castor seed oil, sunflower seed oil, lavender oil, shea butter, olive oil, coconut palm oil, and grape seed oil in equal proportions was used. The palm fruit oil acts as an ingredient that helps strengthen the skin barrier and improve moisture retention ability. Rice bran oil is rich in antioxidants, which contributes to preventing skin aging and improving skin tone. Castor seed oil improves skin elasticity and provides soothing effects due to its high content of omega-3 fatty acids. Sunflower seed oil has a high concentration of vitamin E, which supports skin antioxidant activity and has a soothing effect on irritated skin. Lavender oil has an excellent soothing effect and helps with acne or troubled skin. Shea butter has excellent moisture locking ability and is suitable for dry skin. Olive oil is effective in moisturizing the skin and promoting softness. Coconut palm oil provides deep nourishment and moisturizing effects to the skin. Grapeseed oil is rich in antioxidants, which can help prevent skin aging and improve flexibility.
본 발명의 화장료 조성물은 상기 곡물가루 혼합물 100 중량부에 대하여, 상기 한약재 혼합 추출물 5 내지 15 중량부, 상기 오일 혼합물 3 내지 8 중량부를 포함하여 제조되는 것일 수 있고, 더욱 구체적으로는 곡물가루 혼합물 100 중량부 대비 한약재 혼합 추출물 10 중량부, 상기 오일 혼합물 5 중량부를 포함하여 제조된 것일 수 있으나, 이에 제한되는 것은 아니다.The cosmetic composition of the present invention may be prepared by comprising 5 to 15 parts by weight of the herbal medicine mixed extract and 3 to 8 parts by weight of the oil mixture, based on 100 parts by weight of the grain powder mixture, and more specifically, 100 parts by weight of the grain powder mixture. It may be prepared by including 10 parts by weight of herbal medicine mixed extract and 5 parts by weight of the oil mixture, but is not limited thereto.
상기 한약재 혼합 추출물이 5 중량부보다 적게 포함되는 경우에는 이를 포함하지 않은 경우와 비슷한 정도의 효과밖에 보이지 못하여 사실상 효과를 발휘하지 못하였고, 15중량부보다 많이 포함되는 경우에는 한약재의 향이 너무 강해 전반적인 선호도가 급격히 하락하였다. If the mixed extract of the herbal medicine was included in less than 5 parts by weight, the effect was only similar to that of the case without it, and was virtually ineffective, and if it was included in more than 15 parts by weight, the scent of the herbal medicine was too strong, causing overall damage. Preference dropped sharply.
상기 오일 혼합물이 3 중량부보다 적게 포함되는 경우에는 효과를 발휘하지 못하였고, 8 중량부보다 과하게 포함되는 경우에는 최종적으로 분말화 된 형태에서 스스로 응집하는 현상이 발생하여 장기간 보관시 쉽게 굳어져 사용성이 현저히 떨어지고, 끈적한 느낌이 들어 별로라는 반응이 다수 발생하였다.If the oil mixture was contained in less than 3 parts by weight, it was not effective, and if it was contained in excess than 8 parts by weight, self-agglomeration occurred in the final powdered form, and it hardened easily when stored for a long time, making it usable. There were many reactions that said it was not good because it fell off significantly and felt sticky.
본 발명에서의 용어 “피부 개선”은 피부 미백, 피부 주름 개선, 피부 재생, 피부 보습 개선, 기미 개선, 여드름 완화 및 외부 자극에 의한 손상 피부 장벽 개선 중 어느 하나 이상을 포함할 수 있다. 본 발명에서는 피부 미백 및 기미 개선, 여드름 완화 및 주름 개선 효과를 확인하였으나, 이에 제한되는 것은 아니다.The term “skin improvement” in the present invention may include any one or more of skin whitening, skin wrinkle improvement, skin regeneration, skin moisturizing improvement, blemish improvement, acne relief, and improvement of skin barrier damaged by external stimuli. In the present invention, the effects of skin whitening, blemish improvement, acne relief, and wrinkle improvement were confirmed, but are not limited thereto.
또한 본 발명의 일 실시예에서 색소 침착 및 이를 통한 피부 미백 효능을 확인한 결과 멜라닌 형성 저해 효과가 우수하게 나타났으며, 인체 실험을 통해 일정 기간 도포한 결과, 피부의 색소침착 및 피부 밝기 개선에 효과적임을 확인하였다. In addition, as a result of confirming pigmentation and skin whitening efficacy through this in an embodiment of the present invention, the effect of inhibiting melanin formation was excellent, and as a result of application for a certain period of time through human experiments, it was effective in improving skin pigmentation and skin brightness. It was confirmed that it was.
상기 화장료 조성물의 제형은 특별히 제한되는 바가 없으며, 예를 들어, 용액, 외용 연고, 크림, 리퀴드, 폼, 영양 화장수, 유연 화장수, 팩, 유연수, 바디워시, 유액, 메이크업 베이스, 에센스, 비누, 액체 세정료, 입욕제, 선 스크린 크림, 선 오일, 현탁액, 유탁액, 페이스트, 겔, 로션, 파우더, 비누, 폼 클렌징, 오일, 분말 파운데이션, 유탁액 파운데이션, 왁스 파운데이션, 패치 및 스프레이 중 어느 하나의 제형을 가질 수 있다.The formulation of the cosmetic composition is not particularly limited, and includes, for example, solution, external ointment, cream, liquid, foam, nourishing lotion, softening lotion, pack, softening water, body wash, emulsion, makeup base, essence, soap, liquid. Any of the following formulations: cleanser, bath bomb, sunscreen cream, sun oil, suspension, emulsion, paste, gel, lotion, powder, soap, foam cleansing, oil, powder foundation, emulsion foundation, wax foundation, patch, and spray. You can have
상기 화장료의 조성물은 화장료의 제형 또는 사용 목적에 맞게 임의로 선정한 물질을 첨가할 수 있다. 예를 들어, 정제수, 유분, 계면활성제, 보습제, 고급알코올, 증저점제, 킬레이트제, 색소, 지방산, 산화방지제, 방부제, 왁스, pH조절제, 향료 등이 첨가될 수 있으나, 이에 제한되지 않을 수 있다.The cosmetic composition may contain materials arbitrarily selected to suit the formulation or purpose of use of the cosmetic. For example, purified water, oil, surfactant, moisturizer, higher alcohol, viscosity increasing agent, chelating agent, colorant, fatty acid, antioxidant, preservative, wax, pH adjuster, fragrance, etc. may be added, but may not be limited thereto. there is.
상기 화장료 조성물의 제형이 페이스트, 크림 또는 젤인 경우, 담체 성분으로서 동물성유, 식물성유, 왁스, 파라핀, 전분, 트라칸트, 셀룰로오스 유도체, 폴리에틸렌 글리콜, 실리콘, 벤토나이트, 실리카, 탈크 또는 산화아연 등을 포함할 수 있으나 이에 제한되지 않을 수 있다.When the formulation of the cosmetic composition is a paste, cream or gel, the carrier ingredients include animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide. It may be possible, but may not be limited to this.
상기 화장료 조성물의 제형이 파우더 또는 스프레이인 경우, 담체 성분으로서 락토스, 탈크, 실리카, 알루미늄 히드록시드, 칼슘 실리게이트 또는 폴리아미드 파우더를 포함할 수 있고, 특히 스프레이인 경우 추가적으로 클로로플루오로히드로카본, 프로판/부탄 또는 디메틸 에테르와 같은 추진제를 포함할 수 있으나, 이에 제한되지 않을 수 있다. When the formulation of the cosmetic composition is powder or spray, it may include lactose, talc, silica, aluminum hydroxide, calcium silicate, or polyamide powder as carrier ingredients, and especially in the case of spray, chlorofluorohydrocarbon, It may include, but is not limited to, propellants such as propane/butane or dimethyl ether.
상기 화장료 조성물의 제형이 용액 또는 유탁액인 경우, 담체 성분으로서 용매, 용해화제 또는 유탁화제를 포함할 수 있고, 예를 들어, 물, 에탄올, 이소프로판올, 에틸 카보네이트, 에틸 아세테이트, 벤질 알코올, 벤질 벤조에이트, 프로필렌글리콜, 1,3-부틸글리콜 오일, 글리세롤 지방족 에스테르, 폴리에틸렌 글리콜 또는 소르비탄의 지방산 에스테르를 포함할 수 있으나, 이에 제한되지 않을 수 있다. When the formulation of the cosmetic composition is a solution or emulsion, it may include a solvent, solubilizing agent, or emulsifying agent as a carrier component, for example, water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, and benzyl benzoate. It may include, but is not limited to, fatty acid esters of ester, propylene glycol, 1,3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol, or sorbitan.
상기 화장료 조성물의 제형이 현탁액인 경우, 담체 성분으로서 물, 에탄올 또는 프로필렌글리콜과 같은 액상의 희석제, 에톡실화 이소스테아릴 알코올, 폴리옥시에틸렌 소르비톨 에스테르 및 폴리옥시에틸렌 소르비탄 에스테르와 같은 현탁제, 미소 결정성 셀룰로오스, 알루미늄 메타히드록시드, 벤토나이트, 아가 또는 트라칸트 등을 포함할 수 있으나, 이에 제한되지 않을 수 있다.When the formulation of the cosmetic composition is a suspension, the carrier ingredients include water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester, and polyoxyethylene sorbitan ester, and miso. It may include, but is not limited to, crystalline cellulose, aluminum metahydroxide, bentonite, agar, or tracant.
상기 화장료 조성물의 제형이 계면-활성제 함유 클렌징인 경우, 담체 성분으로서 지방족 알코올 설페이트, 지방족 알코올 에테르 설페이트, 설포숙신산 모노에스테르, 이세티오네이트, 이미다졸리늄 유도체, 메틸타우레이트, 사르코시네이트, 지방산 아미드 에테르 설페이트, 알칼아미도베타인, 지방족 알코올, 지방산 글리세리드, 지방산 디에탄올아미드, 식물성유, 라놀린 유도체 또는 에톡실화 글리세롤 지방산 에스테르 등을 포함할 수 있으나, 이에 제한되지 않을 수 있다.When the formulation of the cosmetic composition is a surfactant-containing cleansing agent, the carrier component may include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyl taurate, sarcosinate, fatty acid. It may include, but is not limited to, amide ether sulfate, alkalamidobetaine, fatty alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative, or ethoxylated glycerol fatty acid ester.
본 발명의 조성물은 피부에 직접 도포하거나 살포하는 등의 경피 투여 방법으로 사용될 수 있으며, 본 발명 조성물의 투여 경로는 목적조직에 도달할 수 있는 한 어떠한 일반적인 경로를 통하여 투여될 수 있다. The composition of the present invention can be used by transdermal administration methods such as direct application or spraying to the skin, and the composition of the present invention can be administered through any general route as long as it can reach the target tissue.
본 발명의 조성물의 사용량은 연령, 병변의 정도 등의 개인 차이나 제형에 따라 적절하게 조절될 수 있으며, 1일 1회 내지 수회 적?韜?을 피부에 도포하여 1 주일 내지 수개월 사용될 수 있다.The amount used of the composition of the present invention can be appropriately adjusted depending on individual differences such as age and degree of lesion, and the formulation. It can be applied to the skin once or several times a day and used for one week to several months.
본 발명의 화장료 조성물은 곡물 및 한약재 등의 천연 재료로부터 유래한 것으로서 인체 유해성이 없을 뿐 아니라, 여드름 완화, 피부 주름 개선, 기미 개선 및 피부 미백의 복합적인 효과를 나타내는 바, 활용 가능성이 매우 높다. The cosmetic composition of the present invention is derived from natural ingredients such as grains and herbal medicine, and is not harmful to the human body. It also has a complex effect of alleviating acne, improving skin wrinkles, improving freckles, and whitening the skin, so it has a very high possibility of being utilized.
본 발명의 효과는 상기한 효과로 한정되는 것은 아니며, 본 발명의 상세한 설명 또는 청구범위에 기재된 발명의 구성으로부터 추론 가능한 모든 효과를 포함하는 것으로 이해되어야 한다. The effects of the present invention are not limited to the effects described above, and should be understood to include all effects that can be inferred from the configuration of the invention described in the detailed description or claims of the present invention.
이하, 본 발명을 실시예에 의해 상세히 설명한다. 단, 하기 실시예는 본 발명을 예시하는 것일 뿐, 본 발명이 하기 실시예에 의해 한정되는 것은 아니다.Hereinafter, the present invention will be described in detail by examples. However, the following examples are merely illustrative of the present invention, and the present invention is not limited by the following examples.
실시예 1. 화장료 조성물의 제조Example 1. Preparation of cosmetic composition
실시예 1-1 곡물 혼합물의 제조Example 1-1 Preparation of grain mixture
본 발명의 화장료 조성물을 제조하기 위하여, 우선 12종의 식물 혼합물을 분쇄하고 건조하여 곡물 혼합물을 준비하였다. To prepare the cosmetic composition of the present invention, a grain mixture was prepared by first grinding and drying a mixture of 12 types of plants.
구체적으로, 10종의 곡물인 현미, 기장, 서리태, 율무, 귀리, 보리, 수수, 팥, 녹두, 흑미, 좁쌀을 모두 같은 중량비로 혼합하고, 산자나무 열매는 현미의 0.5배, 키위는 현미의 0.1배가 되도록 혼합하고, 분쇄한 뒤 이를 건조하여 곡물 혼합물을 준비하였다.Specifically, 10 types of grains, such as brown rice, millet, seaweed, coix seed, oats, barley, sorghum, red beans, mung beans, black rice, and millet, are all mixed in the same weight ratio, sea buckthorn fruit is 0.5 times the amount of brown rice, and kiwi is 0.5 times the amount of brown rice. It was mixed to a volume of 0.1, pulverized, and dried to prepare a grain mixture.
실시예 1-2. 한약재 혼합 추출물의 제조Example 1-2. Preparation of herbal medicine mixed extract
본 발명의 한약재 혼합 추출물은 제1 내지 3 한약재 혼합 추출물을 각각 제조한 뒤, 제1, 2, 3 한약재 혼합 추출물이 순서대로 각각 1:3:1의 비율이 되도록 혼합하여 제조하였다. The herbal medicine mixed extract of the present invention was prepared by preparing the first to third herbal medicine mixed extracts, and then mixing the first, second, and third herbal medicine mixed extracts in that order at a ratio of 1:3:1.
구체적으로, 제1한약재 혼합 추출물은 13종의 한약재인 오미자, 녹용, 백복령, 솔잎, 백작약, 인삼, 산수유, 황기, 뽕잎, 황기, 구기자, 녹차, 감초가 혼합된 것으로서, 녹용을 제외한 나머지 12종의 한약재는 동일한 중량으로 포함되며, 녹용은 오미자 중량의 0.1 중량부가 되도록 혼합하였다. 이후 상기 혼합물을 100℃의 정제수를 이용하여 4시간동안 열수추출하고 감압 농축하여 본 발명 제1한약재 혼합 추출물을 수득하였다. Specifically, the first mixed extract of herbal medicine is a mixture of 13 kinds of herbal medicines, Schisandra chinensis, deer antler, Baekbokryeong, pine needles, Paeonia, ginseng, Cornus officinalis, astragalus, mulberry leaf, astragalus, goji berry, green tea, and licorice. Excluding deer antler, the remaining 12 kinds. Herbal medicines were included in the same weight, and deer antler was mixed in an amount of 0.1 part by weight based on the weight of Schisandra chinensis. Afterwards, the mixture was subjected to hot water extraction using purified water at 100°C for 4 hours and concentrated under reduced pressure to obtain the first herbal medicine mixed extract of the present invention.
상기 제2한약재 혼합 추출물은 12종의 한약재인 백지, 백급, 백렴, 백강잠, 백부자, 천화분, 감송향, 삼내자, 곽향, 영릉향, 방풍, 고본을 모두 동일 중량으로 혼합한 후에 100℃의 정제수로 6시간동안 열수추출 후 감압 농축하여 제조하였다.The second mixed extract of herbal medicine is made by mixing 12 kinds of herbal medicines, Baekji, Baekgeup, Baekryeom, Baekgangjam, Baekbuja, Cheonhwabun, Spikenthhyang, Samnaeja, Gwakhyang, Yeongneunghyang, Bangpung, and Gobon in equal weight and then soaking them in purified water at 100℃. It was prepared by hot water extraction for 6 hours and then concentration under reduced pressure.
상기 제3한약재 혼합 추출물은 6종의 한약재인 조각자, 생지황, 황금, 황백, 치자, 백수오가 2:2:1:2:2:1의 중량비가 되도록 혼합한 후에 100℃의 정제수로 6시간동안 열수추출 후 감압 농축하여 제조하였다.The third herbal medicine mixed extract is made by mixing 6 kinds of herbal medicines, such as chives, fresh rehmannia, goldenrod, yellow white, gardenia, and white water, in a weight ratio of 2:2:1:2:2:1, and then soaking in purified water at 100°C for 6 hours. It was prepared by hot water extraction and concentration under reduced pressure.
실시예 1-3. 오일 혼합물의 제조Example 1-3. Preparation of oil mixture
본 발명에서 사용한 오일 혼합물은 팜열매 오일, 쌀겨 오일, 피마자씨 오일, 해바라기씨 오일, 라벤더 오일, 시어버터, 올리브오일, 코코넛야자오일, 포도씨오일을 동일한 부피비율로 혼합한 뒤 사용하였다.The oil mixture used in the present invention was made by mixing palm fruit oil, rice bran oil, castor seed oil, sunflower seed oil, lavender oil, shea butter, olive oil, coconut palm oil, and grape seed oil in equal volume ratios.
실시예 1-4. 화장료 조성물의 제조Example 1-4. Preparation of cosmetic compositions
상기 곡물 혼합물 100 중량부 대비, 한약재 혼합 추출물 10 중량부 및 오일 혼합물 5 중량부를 혼합하여 실시예 1의 화장료 조성물을 제조하였다.The cosmetic composition of Example 1 was prepared by mixing 10 parts by weight of the herbal medicine mixed extract and 5 parts by weight of the oil mixture with 100 parts by weight of the grain mixture.
구체적으로, 곡물 혼합물 100 중량부에 한약재 혼합 추출물 10 중량부를 붓고 교반하고, 오일 혼합물 5중량부가 충분히 잘 스며들도록 소량씩 첨가하면서 계속해서 교반하였다. 이후 굳을 때까지 방치한 후에 다시 분쇄하는 과정을 거쳐 본 발명 실시예 1의 화장료 조성물을 제조하였다.Specifically, 10 parts by weight of the mixed extract of herbal medicine was poured into 100 parts by weight of the grain mixture and stirred, and 5 parts by weight of the oil mixture was added in small amounts so that it could sufficiently permeate while continuing to stir. Afterwards, the cosmetic composition of Example 1 of the present invention was prepared by leaving it until it hardened and then grinding it again.
비교예 1 내지 5. 조성을 달리한 화장료 조성물의 제조Comparative Examples 1 to 5. Preparation of cosmetic compositions with different compositions
실시예 1과 동일한 방법으로 제조하되, 하기 표 1에 정리된 바와 같이 각각의 조성비를 달리 하여 비교예 1 내지 5의 화장료 조성물을 제조하였다.Cosmetic compositions of Comparative Examples 1 to 5 were prepared in the same manner as in Example 1, but with different composition ratios as summarized in Table 1 below.
실험예 1. 여드름 완화 및 피부 진정효과 확인Experimental Example 1. Confirmation of acne relief and skin soothing effect
본 발명 화장료 조성물의 여드름 완화 효과를 확인하기 위하여 시료를 한천 희석법(agar dilution method)으로 여드름균을 접종한 후 37℃ 혐기상태에서 48시간 동안 배양하고, 디스크 확산법을 이용하여 실시예 1 및 비교예 1 내지 5의 화장료 조성물의 항균력을 측정하였다. 실시예 1의 성장저지환의 크기를 100%하여, 상대적인 효과를 하기 표 2에 나타내었다.In order to confirm the acne alleviating effect of the cosmetic composition of the present invention, samples were inoculated with Acne bacteria using the agar dilution method, cultured for 48 hours in anaerobic conditions at 37°C, and Example 1 and Comparative Examples were obtained using the disk diffusion method. The antibacterial activity of the cosmetic compositions 1 to 5 was measured. The size of the growth-inhibiting ring of Example 1 was set to 100%, and the relative effects are shown in Table 2 below.
사멸효과acne bacteria
Extinction effect
그 결과, 상기 표 2에 나타난 바와 같이, 한약재 혼합 추출물을 제외한 비교예 1 및 한약재 혼합 추출물의 비율을 낮춘 비교예 4의 경우 현저한 효과 하락이 확인되었으며, 오일 혼합물을 포함하지 않은 비교예 2의 경우도 효과 하락이 확인되었다.As a result, as shown in Table 2 above, a significant decrease in effectiveness was confirmed in the case of Comparative Example 1 excluding the herbal medicine mixed extract and Comparative Example 4 in which the ratio of the herbal medicine mixed extract was lowered, and in the case of Comparative Example 2 which did not include the oil mixture A decrease in effectiveness was also confirmed.
반면, 오일 혼합물을 과량 포함한 비교예 3 및 한약재 혼합 추출물을 과량 포함한 비교예 5의 경우 다소간의 효과 상승이 확인되었으나, 비교예 3은 끈적한 느낌이 들어 선호도가 하락할 뿐 아니라, 분말이 스스로 응집하여 굳어지는 문제점이 발생하였으며, 비교예 5의 경우 약냄새가 너무 강해 화장료 조성물로의 활용도가 떨어진다는 피드백이 확인되었다.On the other hand, in the case of Comparative Example 3, which contained an excessive amount of oil mixture, and Comparative Example 5, which contained an excessive amount of mixed extract of herbal medicine, a slight increase in effect was confirmed. However, Comparative Example 3 not only had a sticky feeling, which lowered the preference, but also the powder self-agglomerated and hardened. A problem arose, and in the case of Comparative Example 5, feedback was confirmed that the medicinal smell was too strong and the usability as a cosmetic composition was low.
실험예2. 피부 주름 개선 효과 확인Experimental example 2. Confirm the effect of improving skin wrinkles
상기 실시예 및 비교예에서 제조된 화장료 조성물의 피부 주름 개선 효과를 인체를 대상으로 확인하였다. 본 실험예는 20세 내지 60세의 남녀 30명을 대상으로 하였으며, 각각 5명씩 6개의 그룹으로 나누어 1달간 세안시 꾸준히 사용하도록 하고, 해당 실험기간에는 평소 사용하던 화장품의 종류나 사용량을 최대한 유지하도록 하고, 1달이 경과한 후의 피부 주름 개선 효과에 대하여 평가하였다. The skin wrinkle improvement effect of the cosmetic composition prepared in the above Examples and Comparative Examples was confirmed on human subjects. This experimental example was conducted on 30 men and women aged 20 to 60. They were divided into 6 groups of 5 people each and were asked to use them consistently when washing their face for 1 month. During the experiment period, the types and amounts of cosmetics used were maintained as much as possible. The effect of improving skin wrinkles after one month was evaluated.
평가 기준은 매우 효과가 있다(5점), 효과가 있다(4점), 보통이다(3점), 효과가 없다(2점), 전혀 효과가 없다(1점)으로 하여 그 결과를 하기 표 3에 나타내었다.The evaluation criteria are very effective (5 points), effective (4 points), average (3 points), not effective (2 points), and not effective at all (1 point), and the results are shown in the table below. It is shown in 3.
상기 표 3에서 확인할 수 있듯이, 실시예 1의 결과가 가장 우수하였으며, 비교예 3, 5의 경우 우수한 효과를 보였으나, 실험예 1때와 마찬가지로 끈적거리는 사용감에 대한 불만(비교예 3)과 강한 향에 대한 불호도가 심해(비교예 5) 매일 사용하기에는 적합하지 않았다.As can be seen in Table 3, the results of Example 1 were the best, and Comparative Examples 3 and 5 showed excellent effects, but as in Experimental Example 1, there were complaints about the sticky feeling (Comparative Example 3) and strong Because of the severe dislike of the scent (Comparative Example 5), it was not suitable for daily use.
실험예 3. 기미 개선 및 미백 효과 측정Experimental Example 3. Measurement of freckle improvement and whitening effect
멜라닌 함량 분석(melanin contents assay)를 통해 실시예 및 비교예의 시료에 의한 멜라닌 형성 저해능을 평가하였다.The ability to inhibit melanin formation by the samples of Examples and Comparative Examples was evaluated through melanin contents assay.
먼저 실시예 및 비교예의 시료를 정제수에 50 mg/L 농도로 각각 현탁한 후 멜라닌 생성량을 평가하였다. 60 mm 컬쳐 디쉬(culture dish)에 B16F10 세포를 1.5X105 cells/well의 농도로 접종한 후 24시간 동안 배양하였다. 멜라닌 형성을 촉진하는 호르몬인 α-MSH(Sigma-Aldrich, St. Louis, MO, USA)와 실시예 및 비교예의 시료를 50 mg/L 농도로 배지에 투입하였다(Virador VM et al, 1999).First, the samples of Examples and Comparative Examples were each suspended in purified water at a concentration of 50 mg/L, and then the amount of melanin produced was evaluated. B16F10 cells were inoculated into a 60 mm culture dish at a concentration of 1.5X10 5 cells/well and cultured for 24 hours. α-MSH (Sigma-Aldrich, St. Louis, MO, USA), a hormone that promotes melanin formation, and the samples of Examples and Comparative Examples were added to the medium at a concentration of 50 mg/L (Virador VM et al, 1999).
48시간 경과 후, 세포를 수확하여 PBS로 1회 세척한 후 1N NaOH 용출 버퍼 120 uL를 넣고 95℃에서 10분간 가열하여 세포를 용해하였다. 마이크로플레이트 리더(microplate reader)를 이용하여 450 nm 파장에서 흡광도를 측정하였으며, 대조군으로 100 ug/mL 농도의 알부틴(albutin)을 사용하였다.After 48 hours, the cells were harvested and washed once with PBS, then 120 uL of 1N NaOH elution buffer was added and heated at 95°C for 10 minutes to lyse the cells. Absorbance was measured at a wavelength of 450 nm using a microplate reader, and arbutin at a concentration of 100 ug/mL was used as a control.
[식 1][Equation 1]
멜라닌 생성 억제율(%) = 100X(1-(각 시험물질의 흡광도/대조군의 흡광도))Melanin production inhibition rate (%) = 100X (1-(absorbance of each test substance/absorbance of control group))
그 결과, 상기 표 4에 나타난 바와 같이, 실시예 1 및 비교예 3이 우수한 효과를 나타내었다.As a result, as shown in Table 4, Example 1 and Comparative Example 3 showed excellent effects.
전술한 본 발명의 설명은 예시를 위한 것이며, 본 발명이 속하는 기술 분야의 통상의 지식을 가진 자는 본 발명의 기술적 사상이나 필수적인 특징을 변경하지 않고서 다른 구체적인 형태로 쉽게 변형이 가능하다는 것을 이해할 수 있을 것이다. 그러므로 이상에서 기술한 실시 예들은 모든 면에서 예시적인 것이며 한정적이 아닌 것으로 이해해야만 한다. 예를 들어, 단 일형으로 설명되어 있는 각 구성 요소는 분산되어 실시될 수도 있으며, 마찬가지로 분산된 것으로 설명되어 있는 구성 요소들도 결합된 형태로 실시될 수 있다.The above description of the present invention is for illustrative purposes, and those skilled in the art will understand that the present invention can be easily modified into other specific forms without changing the technical idea or essential features of the present invention. will be. Therefore, the embodiments described above should be understood in all respects as illustrative and not restrictive. For example, each component described as a single type may be implemented in a distributed form, and similarly, components described as distributed may also be implemented in a combined form.
본 발명의 범위는 후술하는 청구범위에 의하여 나타내어지며, 청구범위의 의미 및 범위 그리고 그 균등 개념으로부터 도출되는 모든 변경 또는 변형된 형태가 본 발명의 범위에 포함되는 것으로 해석되어야 한다.The scope of the present invention is indicated by the claims described below, and all changes or modified forms derived from the meaning and scope of the claims and their equivalent concepts should be construed as being included in the scope of the present invention.
Claims (5)
상기 곡물 혼합물은,
현미, 기장, 서리태, 율무, 귀리, 보리, 수수, 팥, 녹두, 흑미 및 좁쌀의 곡물 10종과 산자나무 열매 및 키위를 포함하여 총 12종의 식물을 건조 후 분말화하여 혼합한 것이고,
상기 한약재 혼합 추출물은,
오미자, 녹용, 백복령, 솔잎, 백작약, 인삼, 산수유, 황기, 뽕잎, 구기자, 녹차 및 감초로부터 추출된 제1 한약재 혼합 추출물;
백지, 백급, 백렴, 백강잠, 백부자, 천화분, 감송향, 삼내자, 곽향, 영릉향, 방풍 및 고본으로부터 추출된 제2한약재 혼합 추출물; 및
조각자, 생지황, 황금, 황백, 치자 및 백수오로부터 추출된 제3 한약재 혼합 추출물;을 혼합한 것이고,
상기 오일 혼합물은,
팜열매 오일, 쌀겨 오일, 피마자씨 오일, 해바라기씨 오일, 라벤더 오일, 시어버터, 올리브오일, 코코넛야자오일 및 포도씨오일의 9종을 포함하여 제조되는 것인,
피부 개선용 화장료 조성물.Containing a grain mixture, herbal medicine mixed extract and oil mixture in a weight ratio of 100:10:5,
The grain mixture is,
It is a mixture of a total of 12 types of plants, including 10 types of grains such as brown rice, millet, seaweed, coix, oats, barley, sorghum, red beans, mung beans, black rice, and millet, as well as sea buckthorn fruit and kiwi, dried, powdered, and mixed.
The herbal medicine mixed extract,
The first herbal medicine mixed extract extracted from Schisandra chinensis, deer antler, Baekbokryeong, pine needles, white peony, ginseng, Cornus officinalis, astragalus, mulberry leaf, goji berry, green tea and licorice;
Mixed extracts of secondary herbal medicines extracted from Baekji, Baekgeup, Baekryeom, Baekganjam, Baekbuja, Cheonhwabun, Spikensonhyang, Samnaeja, Gwakhyang, Yeongneunghyang, Bangpung and Gobon; and
It is a mixture of the third herbal medicine mixed extract extracted from Sculptor, Saengji Huang, Golden, Hwangbaek, Gardenia and Baeksoo,
The oil mixture is,
It is manufactured including 9 types of palm fruit oil, rice bran oil, castor seed oil, sunflower seed oil, lavender oil, shea butter, olive oil, coconut palm oil and grape seed oil,
Cosmetic composition for improving skin.
상기 곡물 혼합물은 현미, 기장, 서리태, 율무, 귀리, 보리, 수수, 팥, 녹두, 흑미, 좁쌀은 모두 같은 중량으로 혼합하고, 산자나무 열매는 현미의 0.5배 중량, 키위는 현미의 0.1배 중량이 되도록 혼합한 것이고,
상기 한약재 혼합 추출물은 상기 제1, 제2 및 제3 한약재 혼합 추출물을 1:3:1의 중량비로 혼합한 것이고,
상기 제1 한약재 혼합 추출물은 오미자, 백복령, 솔잎, 백작약, 인삼, 산수유, 황기, 뽕잎, 구기자, 녹차 및 감초는 동일한 중량으로 혼합하고, 녹용을 상기 오미자 중량의 0.1 중량부가 되도록 혼합한 혼합물로부터 열수추출 된 것이고,
상기 제2 한약재 혼합 추출물은 백지, 백급, 백렴, 백강잠, 백부자, 천화분, 감송향, 삼내자, 곽향, 영릉향, 방풍 및 고본이 동일 중량으로 혼합된 혼합물로부터 열수추출 된 것이고,
상기 제3 한약재 혼합물은 조각자, 생지황, 황금, 황백, 치자 및 백수오를 2:2:1:2:2:1 중량비로 혼합한 혼합물로부터 열수추출 된 것이고,
상기 오일 혼합물은 팜열매 오일, 쌀겨 오일, 피마자씨 오일, 해바라기씨 오일, 라벤더 오일, 시어버터, 올리브오일, 코코넛야자오일 및 포도씨오일을 동일한 부피로 혼합한 것인,
피부 개선용 화장료 조성물. According to paragraph 1,
The grain mixture includes brown rice, millet, seaweed, coix radish, oats, barley, sorghum, red beans, mung beans, black rice, and millet, all mixed in equal weight, sea buckthorn fruit at 0.5 times the weight of brown rice, and kiwi at 0.1 times the weight of brown rice. It was mixed so that
The herbal medicine mixed extract is a mixture of the first, second and third herbal medicine mixed extracts at a weight ratio of 1:3:1,
The first mixed extract of herbal medicine is obtained by mixing equal weights of Schisandra chinensis, Baekbokryeong, pine needles, Paeonia, ginseng, Cornus officinalis, Astragalus, mulberry leaf, Goji berry, green tea and licorice, and mixing deer antler in an amount of 0.1 part by weight of the weight of Schisandra chinensis. It was extracted,
The second herbal medicine mixed extract is hot water extracted from a mixture of equal weight of Baekji, Baekgeup, Baekryeom, Baekgangjam, Baekbuja, Cheonhwabun, Gamsonhyang, Samnaeja, Gwakhyang, Yeongneunghyang, Bangpung and Gobon,
The third herbal medicine mixture was hot water extracted from a mixture of Scallop, Saenghwang, Golden, Hwangbaek, Gardenia and Baeksoo in a weight ratio of 2:2:1:2:2:1,
The oil mixture is an equal volume of palm fruit oil, rice bran oil, castor seed oil, sunflower seed oil, lavender oil, shea butter, olive oil, coconut palm oil, and grape seed oil,
Cosmetic composition for improving skin.
상기 피부 개선은 여드름 완화, 피부 미백 및 피부 주름 개선인, 피부 개선용 화장료 조성물.According to claim 1 or 2,
A cosmetic composition for improving skin, wherein the skin improvement includes alleviating acne, whitening skin, and improving skin wrinkles.
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| KR102716642B1 (en) * | 2024-02-13 | 2024-10-16 | (주)트윈켐 | Cosmetic composition having hair loss-proof and growth accelerating effect |
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| KR20040090644A (en) * | 2003-04-18 | 2004-10-26 | (주)휴먼엘씨에스코리아 | Cosmetic composition containing grain extract and fermented grain phellinus linteus extract, and cosmetics containing the same |
| KR20090034241A (en) * | 2007-10-02 | 2009-04-07 | 동국대학교 산학협력단 | Fermentation method of natural plant material and herbal medicine, fermented product prepared by the above method and pharmaceutical composition, cosmetic composition and food composition containing the same |
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| KR102716642B1 (en) * | 2024-02-13 | 2024-10-16 | (주)트윈켐 | Cosmetic composition having hair loss-proof and growth accelerating effect |
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| KR20240142281A (en) | 2024-09-30 |
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