JPS56128721A - Antiallergic agent - Google Patents
Antiallergic agentInfo
- Publication number
- JPS56128721A JPS56128721A JP3030880A JP3030880A JPS56128721A JP S56128721 A JPS56128721 A JP S56128721A JP 3030880 A JP3030880 A JP 3030880A JP 3030880 A JP3030880 A JP 3030880A JP S56128721 A JPS56128721 A JP S56128721A
- Authority
- JP
- Japan
- Prior art keywords
- activity
- bronchial asthma
- antiallergic agent
- compound
- antiallergic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000043 antiallergic agent Substances 0.000 title abstract 3
- 208000006673 asthma Diseases 0.000 abstract 4
- 230000000694 effects Effects 0.000 abstract 4
- 208000030603 inherited susceptibility to asthma Diseases 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 201000009961 allergic asthma Diseases 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 230000007883 bronchodilation Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000002227 vasoactive effect Effects 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PURPOSE: An antiallergic agent that contains a specific basic polypeptide, thus being especially useful as a remedy for bronchial asthma.
CONSTITUTION: The objective antiallergic agent contains a polypetide of the formula, Vasoactive, Intestinal polypeptide (abbreviated to VIP hereinafter) as an active principle. The compound has been isolated from the inside of alimentary tract mucosas and known to have activities of increasing bloodstreams and lowering blood pressures. And now, it has been found to have antiallergic activity. Especially, the compound of the formula has an activity of prohibiting the elimination of chemical mediaton, thus it is useful for treatment and prevention against various kinds of allergoses, e.g., allergic rhinitis, bronchial asthma, or hay fever. Further, it has bronchodilation activity, too, thus being most effectively used for bronchial asthma and allergic asthma. Side-effects also are reduced.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3030880A JPS56128721A (en) | 1980-03-12 | 1980-03-12 | Antiallergic agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3030880A JPS56128721A (en) | 1980-03-12 | 1980-03-12 | Antiallergic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS56128721A true JPS56128721A (en) | 1981-10-08 |
Family
ID=12300137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3030880A Pending JPS56128721A (en) | 1980-03-12 | 1980-03-12 | Antiallergic agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56128721A (en) |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6434923A (en) * | 1987-04-30 | 1989-02-06 | Cooper Lab | Aerosolization of proteinaceous remedy |
| US5376637A (en) * | 1991-04-22 | 1994-12-27 | Sanwa Kagaku Kenkyusho Co., Ltd. | Pharmaceutical preparation containing vasoactive intestinal polypeptide or its analogue |
| US5428015A (en) * | 1990-06-26 | 1995-06-27 | Sana Kagaku Kenkyusho Co., Ltd. | Vasoactive intestinal polypeptide analogues and use thereof |
| WO2004089407A3 (en) * | 2003-03-31 | 2005-01-20 | Brigham & Womens Hospital | Zwitterionic immunomodulators for the treatment of asthma and allergy |
| US8008276B2 (en) | 2000-12-05 | 2011-08-30 | The Brigham And Women's Hospital, Inc. | Use of zwitterionic polysaccharides for the specific modulation of immune processes |
| US8206726B2 (en) | 2006-02-06 | 2012-06-26 | The Brigham And Women's Hospital, Inc. | Zwitterionic polysaccharides for promotion of immune system maturation and health |
| US10772918B2 (en) | 2013-05-10 | 2020-09-15 | California Institute Of Technology | Probiotic prevention and treatment of colon cancer |
| US10857177B2 (en) | 2015-08-19 | 2020-12-08 | President And Fellows Of Harvard College | Lipidated PSA compositions and methods |
| US11103566B2 (en) | 2010-05-20 | 2021-08-31 | California Institute Of Technology | Antigen specific Tregs and related compositions, methods and systems |
| US11331335B2 (en) | 2015-06-10 | 2022-05-17 | California Institute Of Technology | Sepsis treatment and related compositions methods and systems |
| US11419887B2 (en) | 2010-04-07 | 2022-08-23 | California Institute Of Technology | Vehicle for delivering a compound to a mucous membrane and related compositions, methods and systems |
| US11491181B2 (en) | 2016-07-15 | 2022-11-08 | President And Fellows Of Harvard College | Glycolipid compositions and methods of use |
| US11622973B2 (en) | 2007-11-09 | 2023-04-11 | California Institute Of Technology | Immunomodulating compounds and related compositions and methods |
-
1980
- 1980-03-12 JP JP3030880A patent/JPS56128721A/en active Pending
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618786A (en) * | 1987-04-30 | 1997-04-08 | Cooper Laboratories, Inc. | Aerosolization of protein therapeutic agent |
| JPS6434923A (en) * | 1987-04-30 | 1989-02-06 | Cooper Lab | Aerosolization of proteinaceous remedy |
| US5428015A (en) * | 1990-06-26 | 1995-06-27 | Sana Kagaku Kenkyusho Co., Ltd. | Vasoactive intestinal polypeptide analogues and use thereof |
| US5376637A (en) * | 1991-04-22 | 1994-12-27 | Sanwa Kagaku Kenkyusho Co., Ltd. | Pharmaceutical preparation containing vasoactive intestinal polypeptide or its analogue |
| US8008276B2 (en) | 2000-12-05 | 2011-08-30 | The Brigham And Women's Hospital, Inc. | Use of zwitterionic polysaccharides for the specific modulation of immune processes |
| US9265790B2 (en) | 2003-03-31 | 2016-02-23 | The Brigham And Women's Hospital, Inc. | Zwitterionic immunomodulators for the treatment of asthma and allergy |
| AU2004227852B2 (en) * | 2003-03-31 | 2010-01-14 | The Brigham And Women's Hospital, Inc. | Zwitterionic immunomodulators for the treatment of asthma and allergy |
| WO2004089407A3 (en) * | 2003-03-31 | 2005-01-20 | Brigham & Womens Hospital | Zwitterionic immunomodulators for the treatment of asthma and allergy |
| US8206726B2 (en) | 2006-02-06 | 2012-06-26 | The Brigham And Women's Hospital, Inc. | Zwitterionic polysaccharides for promotion of immune system maturation and health |
| US11622973B2 (en) | 2007-11-09 | 2023-04-11 | California Institute Of Technology | Immunomodulating compounds and related compositions and methods |
| US11419887B2 (en) | 2010-04-07 | 2022-08-23 | California Institute Of Technology | Vehicle for delivering a compound to a mucous membrane and related compositions, methods and systems |
| US11103566B2 (en) | 2010-05-20 | 2021-08-31 | California Institute Of Technology | Antigen specific Tregs and related compositions, methods and systems |
| US10772918B2 (en) | 2013-05-10 | 2020-09-15 | California Institute Of Technology | Probiotic prevention and treatment of colon cancer |
| US11331335B2 (en) | 2015-06-10 | 2022-05-17 | California Institute Of Technology | Sepsis treatment and related compositions methods and systems |
| US10857177B2 (en) | 2015-08-19 | 2020-12-08 | President And Fellows Of Harvard College | Lipidated PSA compositions and methods |
| US11491181B2 (en) | 2016-07-15 | 2022-11-08 | President And Fellows Of Harvard College | Glycolipid compositions and methods of use |
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