JPH11244391A - Catheter for image making - Google Patents

Abstract

PROBLEM TO BE SOLVED: To realize correct image making by X ray with the least move at the top end of the catheter that is caused at an angle part when a contrast medium is poured even if it has the bent part (angle part) at the top end. SOLUTION: Catheter 1 for image making consists of a lumen and a catheter tube that has an opening at the top end as it is connected with the lumen. The catheter tube consists of bent part 9 that is formed at the side of the top end, wound and deformed part 2 that is wound as it projects toward inner direction of the bent part and that is shaped at the top end of the catheter tube as it is nearer to the top end than the bent part and side holes composing part 5 that consists of a lot of side holes 4 made between the bent part and the wound and deformed part. The whole area of all the side holes that exist in the interior part of the bent part 9 of the side holes composing part 5 should be smaller than that of all the side holes that exists in the exterior part of the bent part 9 of the side holes composing part 5.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an in-vivo imaging catheter used for angiography of a heart or a tissue around the heart, and imaging of a living organ such as a liver, a pancreas, and a bile duct.

[0002]

2. Description of the Related Art Hitherto, catheters of the Judkins type and Amplatz type have been used as catheters for coronary angiography, and pigtail type catheters have been used as catheters for left ventricular imaging. . For example, a pigtail catheter is introduced into a blood vessel from a femoral artery by the Seldinger method or the sheath method. A guide wire is inserted into the catheter, and by performing operations such as moving the catheter forward and backward and rotating with the guide wire, the bifurcation of the blood vessel is selected and reached to the ascending artery. Insert part into left ventricle. Then, in this state, a contrast agent is supplied from the proximal end side of the catheter, and the contrast agent is ejected from the distal end portion of the catheter into the left ventricle to image the left ventricle.

[0003] As a conventional catheter for coronary angiography, there is a so-called angled pigtail catheter. The angled pigtail type catheter includes a lumen and a catheter tube having a distal end opening communicating with the lumen. The catheter tube has a bent portion (angle portion) formed on the distal side and a distal side (angle of the catheter tube) from the bent portion. And a curved deformation portion (pigtail portion) that is formed at the distal end and that is curved so as to protrude inward of the bent portion. When the contrast agent is injected into the catheter, when the contrast agent passes through the angle portion, the contrast agent hits the inner wall of the angle portion and exerts a force on the inner wall, and the force causes the catheter to move outward from the angle portion. For this reason, there has been a problem that the distal end of the catheter disposed at the target site is displaced, and accurate X-ray imaging is not performed.

[0004]

SUMMARY OF THE INVENTION An object of the present invention is to solve the above-mentioned conventional problems and to provide a bent portion (angle portion) at the distal end.
The present invention provides a contrast catheter capable of performing an accurate X-ray contrast even when the contrast catheter includes:

[0005]

The above object is achieved by providing a catheter tube having a lumen and a distal end opening communicating with the lumen.
A bent portion formed at the distal end side, a curved deformed portion formed at the distal end portion of the catheter tube, and curved to protrude inward of the bent portion, provided between the bent portion and the curved deformed portion. And a side hole forming portion in which a number of side holes communicating with the lumen are formed, and the total area of the side holes located at a portion inside the bent portion of the side hole forming portion is the side An imaging catheter having a smaller area than the total area of side holes located outside the bent portion of the hole forming portion.

Then, a component of a force applied by the injected contrast agent to the bent portion in a direction perpendicular to the axis of the side hole forming portion and discharged from a side hole inside the bent portion of the side hole forming portion. The sum of the component and the component in the same direction in the ejection output of the contrast agent is opposite to the component in the ejection output of the contrast agent ejected from the side hole of the portion outside the bent portion of the side hole forming portion. It is preferable that the component substantially balances with the component.

In order to achieve the above object, a catheter tube having a lumen and a distal end opening communicating with the lumen is provided. The catheter tube has a bent portion formed on the distal end side and a distal end portion of the catheter tube. A curved deformed portion that is formed and curved to protrude inward of the bent portion, and a side provided between the bent portion and the curved deformed portion, on which a plurality of side holes communicating with the lumen are formed. The side hole forming portion has a component in a direction perpendicular to an axis of the side hole forming portion in a force applied by the injected contrast agent to the bending portion and the bending of the side hole forming portion. The sum of the component and the component in the same direction in the ejection power of the contrast agent ejected from the side hole of the portion inside the portion is ejected from the side hole of the portion outside the bent portion of the side hole forming portion. In the ejection power of the contrast agent Serial component opposite direction component to be angiographic catheter side hole is provided so as to substantially balance.

The plurality of side holes may have the same side hole shape and the same opening area. Further, the side hole forming portion includes, for example, an outer side hole row provided in a portion outside the bent portion of the side hole forming portion in parallel with a central axis of the side hole forming portion, and the side hole forming portion. The inner side hole row is provided so as to face the outer side hole row at a portion inside the bent portion of the portion, and has a smaller number of side holes than the outer side hole row. Further, the side hole forming portion includes, for example, an outer side hole row provided in a portion outside the bent portion of the side hole forming portion in parallel with a central axis of the side hole forming portion, and the side hole forming portion. A portion inside the bent portion of the portion is provided so as to face the outer side hole row, and has an inner side hole row composed of side holes having a smaller opening area than the side holes of the outer side hole row. .

In order to achieve the above object, there is provided a catheter tube having a lumen and a distal end opening communicating with the lumen. The catheter tube has a bent portion formed on the distal end side and a distal end portion of the catheter tube. A curved deformed portion that is formed and curved to protrude inward of the bent portion, and a side provided between the bent portion and the curved deformed portion, on which a plurality of side holes communicating with the lumen are formed. A portion of the side hole forming portion, which is inside the bent portion, is a contrast catheter having a side hole non-forming portion. And a component in a direction perpendicular to an axis of the side hole forming portion in a force applied by the injected contrast agent to the bent portion and a contrast agent discharged from a side hole of a portion of the side hole forming portion outside the bent portion. It is preferable that the component in the direction opposite to the above-mentioned component in the ejection power is substantially balanced.

In order to achieve the above object, a catheter tube having a lumen and a distal end opening communicating with the lumen is provided. The catheter tube has a bent portion formed on the distal end side and a distal end portion of the catheter tube. A curved deformed portion that is formed and curved to protrude inward of the bent portion, and a side provided between the bent portion and the curved deformed portion, on which a plurality of side holes communicating with the lumen are formed. The side hole forming portion has a component in a direction perpendicular to an axis of the side hole forming portion in a force applied by the injected contrast agent to the bending portion and the bending of the side hole forming portion. This is a contrast catheter having a side hole formed so as to be substantially balanced with a component in a direction opposite to the above-described component in the ejection power of the contrast agent discharged from a side hole of a portion outside the part. And
The side hole forming portion is, for example, an outer side hole row provided in a portion outside the bent portion of the side hole forming portion in parallel with a central axis of the side hole forming portion, and a side hole forming portion. A side hole non-forming portion is provided in a portion inside the bent portion so as to face the outer side hole row. The plurality of side holes may have the same side hole shape and the same opening area.

The side hole forming portion includes a right side surface side hole array provided in a portion of the side hole forming portion on the right side of the bent portion in parallel with a center axis of the side hole forming portion. It is preferable that the side hole forming portion has a left side hole array provided at a portion on the left side of the bent portion so as to face the right side hole array. Furthermore, it is preferable that the right side surface side row and the left side side hole row have the same number of side holes. Further, the side hole forming portion includes a first right side surface side row of holes provided in parallel to a central axis of the side hole forming portion at a portion on the right side of the bent portion of the side hole forming portion; Second
And a first left side surface side provided at a portion of the side hole forming portion which is a left side surface of the bent portion so as to face the first right side side hole line. It is preferable to have a hole row and a second left side hole row provided so as to face the second right side hole row. Further, the first right side hole row and the first left side hole row have the same number of side holes, and the second right side hole row and the second left side hole row have the same number of side holes. The number of side holes in the side hole row is preferably the same. Further, it is preferable that the side holes of the right side hole row and the left side hole row have the same side hole shape and the same opening area. Further, it is preferable that the distal end opening of the catheter is substantially parallel to the axial direction of the main body of the catheter and faces the distal direction. It is preferable that nine or more side holes having an area of 0.8 mm ² or less exist in an arbitrary axial length of 10 mm of the side hole forming portion. Further, the area of the side hole is 0.008 mm.
It is preferably at least ² .

[0012]

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a perspective view of a catheter for in vivo contrast imaging according to the present invention. FIG. 1 is a partially omitted side view of an embodiment of the in-vivo contrast catheter of the present invention. FIG. 2 is an enlarged view of the distal end portion of the catheter shown in FIG. FIG. 3 is an enlarged view of the distal end portion of the catheter shown in FIG. 1 as viewed from the inside of the bent portion. FIG. 4 is an enlarged sectional view of a distal end portion of the catheter shown in FIG.

The imaging catheter 1 of the present invention includes a lumen 8 and a catheter tube 10 having a distal opening 3 communicating with the lumen 8. Catheter tube 10
Is formed at the distal end side of the catheter tube, and at the distal end side of the bent portion 9 and the distal end side of the bent portion 9,
A curved deformation portion 2 that is curved so as to protrude inward of the bent portion 9; and a side hole formed between the bent portion 9 and the curved deformation portion 2 and formed with a number of side holes 4 that communicate with the lumen. A part 5. The total area of the side holes 4 located inside the bent portions 9 of the side hole forming portions 5 is
Is smaller than the total area of the side holes 4 located outside the bent portion 9. For this reason, the side hole forming part 5
Of the contrast medium ejected from the side hole of the part inside the bent portion 9 of the side hole and the ejection power of the contrast agent ejected from the side hole of the part outside the bent part 9 of the side hole forming part 5 Since the buffer is buffered, the behavior of the catheter tip caused by the bending portion 9 during the injection of the contrast agent is small.

Further, in the catheter of the present invention, the side hole forming portion 5 has a component in the direction perpendicular to the axis of the side hole forming portion 5 in the force applied by the injected contrast agent to the bending portion 9 and the side hole forming portion. The same direction (same direction) as the above component in the ejection power of the contrast agent discharged from the side hole of the portion inside the bent portion 9 of the portion 5
Is large so that the component in the direction opposite to the above component in the ejection power of the contrast agent ejected from the side hole of the portion outside the bent portion 9 of the side hole forming portion 5 is substantially balanced. Are provided. In particular, the catheter 1 of this embodiment has an outer side hole row group provided in a portion outside the bent portion 9 of the side hole forming portion 5 in parallel with the central axis of the side hole forming portion 5, and a side hole forming portion 5. An inner side hole row group is provided at a portion inside the bent portion 9 so as to face the outer side hole row and has a smaller number of side holes than the outer side hole row. Therefore, the movement of the distal end of the catheter caused by the bending portion 9 during the injection of the contrast medium is extremely small, and the distal end of the arranged catheter is little moved, so that accurate X-ray imaging can be performed.

The imaging catheter 1 of the present invention is used for imaging living organs such as cardiovascular, liver, pancreas and bile duct. The imaging catheter 1 of this embodiment is a cardiovascular imaging catheter, and has a pigtail-shaped curved deformation portion 2 (pigtail portion) at the distal end, and is formed at the distal end and at the rear end side of the curved deformation portion 2. It has a bent portion 9 (angle portion). The catheter 1 has flexibility as a whole, and the curved deformable portion 2 (pigtail portion) and the bent portion 9 (angle portion) maintain the state without applying external force. Specifically, the catheter 1 includes a catheter tube 10 and a hub 7 fixed to a proximal end of the catheter tube 10. The catheter tube 10 includes a curved deformation section 2, a side hole forming section 5, a bent section 9, and a main body section 6 from the distal end side.

The catheter 1 may be made of, for example, a polyolefin such as polyethylene, polypropylene, or ethylene-vinyl acetate copolymer, or a polyolefin-based elastomer thereof, a polyamide-based resin (eg, nylon 11, nylon 12, nylon 6), or polyester. -Based polyamide resin (for example, product name: GIRAC manufactured by DIC), polyether-based polyamide resin (for example, product name: Pebax, manufactured by Atochem), polyurethane, ABS resin, fluorine-based resin (PFA, PTF)
E, ETFE, etc.) or various synthetic resins such as a soft fluororesin, a polyimide, a shape memory resin, a polymer blend containing them, and a polymer alloy (for example, a polymer alloy of a polyamide elastomer and a polyurethane). In addition, since the insertion of the catheter 1 into a living body is performed while confirming the position thereof under X-ray fluoroscopy, for example, barium sulfate,
An X-ray opaque material such as bismuth oxide or tungsten may be blended.

It is preferable that the curved deformation portion 2 is more flexible than the main body portion 6 and the side hole forming portion 5. In this case, a material that is more flexible than the material of the main body portion and the side hole forming portion, in other words, a material that is highly flexible, is selected as the material for forming the curved deformation portion 2. In order to facilitate the connection between the main body and the side hole forming portion 5 and to increase the bonding strength, a resin forming the curved deformation portion 2 and a resin forming the main body portion and the side hole forming portion 5 are formed. Preferably have good compatibility. Good compatibility means that thermodynamic mutual solubility is good. In other words, it means that there is no separation between the two after curing.

As a combination of resins, it is desirable that both resins have the same system. For example, nylon 12 or a polyether polyamide block copolymer is selected as a material for forming the main body portion and the side hole forming portion 5, and a material having higher flexibility than the polyether polyamide block copolymer is used as a material for forming the curved deformation portion 2. An ether polyamide block copolymer is selected and both are made of a polyamide-based resin.
A polyolefin-based elastomer (for example, polyethylene elastomer) is selected as a forming material of the polyolefin-based elastomer, and a polyolefin-based elastomer (for example, polyethylene elastomer) having higher flexibility than the polyolefin-based elastomer is selected as a forming material of the curved deformation portion 2. And a polyester-based elastomer (for example, a polyester elastomer having a soft segment and a hard segment and having many soft segment portions) as a material for forming the curved deformation portion 2, and a material for forming the main body portion and the side hole forming portion 5. Polyester elastomer (for example, a polyester elastomer having a soft segment and a hard segment and having a soft segment portion less than the material for forming the curved deformation portion 2), and both are made of polyester. Plasticized vinyl chloride resin is selected as a material for forming the main body portion and the side hole forming portion 5, and a high plasticization having higher flexibility than the plasticized vinyl chloride resin as a material for forming the curved deformation portion 2. A vinyl chloride resin is selected and both are vinyl chloride resins. Polyurethane is selected as a material for forming the curved deformation portion 2 and a polymer alloy of polyamide elastomer and polyurethane is selected as a material for forming the main body portion and the side hole forming portion 5. It is conceivable that both are made of polyurethane.

Further, the catheter 1 has a curved deformation portion 2,
An outer layer covering the entirety of the bent portion 9, the main body portion 6 and the side hole forming portion 5 may be provided. As the material for forming the outer layer, a material having adhesiveness to the material for forming the curved deformation portion, the material for forming the main body and the side hole is preferable. Specifically, the same or similar materials as those forming materials are preferable. For example, thermoplastic resins such as polyethylene, polypropylene, polyolefin using ethylene-propylene copolymer, polyvinyl chloride, ethylene-vinyl acetate copolymer, polyamide elastomer, polyurethane, silicone rubber, latex rubber and the like can be used. Preferably, a polyamide elastomer or polyurethane softened by a plasticizer such as paraoxybenzoic ethylhexyl (POBO) can be used. Then, in order to make the outer surface of the catheter 1 smooth, X
It is preferable not to mix the radiopaque material. further,
The outside of the outer layer may be coated with a resin having biocompatibility, especially antithrombotic properties, for example, polyhydroxyethyl methacrylate, a copolymer of hydroxyethyl methacrylate and styrene (for example, HEMA-St-H).
EMA block copolymer) can be used.

Inside the catheter 1, there is formed a lumen 8 which extends from the rear end to the front end and serves as a flow path for a liquid such as a contrast medium. The lumen 8 opens at the distal end of the catheter 1 and forms the distal opening 3. When the catheter 1 is inserted into a living body or the like, a guide wire (not shown) is inserted into the lumen 8. Further, in the catheter 1 of this embodiment, the distal end opening 3 formed at the distal end of the curved deformation portion 2 is substantially parallel to the main body 6 of the catheter tube 10 and the lumen 8 of the side hole forming portion 5 and of the catheter 1. Pointing toward the tip. For this reason, the curved deformation part 2
Is maintained as it is, the contrast medium is discharged from the distal end opening 3 so as to be substantially parallel to the lumen 8 (axis) of the catheter 1.

The outer diameter of the catheter 1 is not particularly limited, but is generally preferably about 0.8 to 3.0 mm,
About 2.5 mm is more preferable. In addition, catheter 1
Is not particularly limited, but is usually 0.1 to 0.7.
mm, preferably about 0.15 to 0.5 mm. The radius (curvature radius) of the curved deformation portion 2 is 3.0
About 15 mm, particularly preferably 3.0 to 15 mm.
8.0 mm.

A bent portion 9 is formed at the distal end of the catheter tube, at a position closer to the base end than the curved deformable portion 2. The bent portion 9 is preferably formed at a position approximately 40 to 100 mm proximal to the distal end of the catheter tube. In other words, in other words, it is preferable that the tangent line X drawn from the rearmost position of the curved deformation portion 2 in FIG. 2 is formed at a position closer to the base end by about 5 to 65 mm than the position crossing the catheter tube. The bending angle of the bending portion 9 is preferably about 90 to 170 degrees. In particular, about 100 to 160 degrees is preferable.

A side hole forming portion 5 is located between the curved deformation portion 2 and the bent portion 9 of the catheter 1, and a large number of minute side holes 4 are formed in the side hole forming portion 5. . The side hole 4 is formed at a position between the rearmost position of the curved deformation portion 2 and the bent portion 9. In other words, the side hole 4 is formed at the same position as the position where the tangent line X drawn from the rearmost end position of the curved deformation portion 2 crosses the catheter tube 10 or at the rear end side and up to the bent portion 9. . The length L in the axial direction of the side hole forming portion 5 is preferably about 5 to 80 mm, and more preferably about 10 to 45 mm. Further, the side hole 4 is located at a rear end side, preferably 1 to 10 mm, particularly preferably 1 to 10 mm, of a position where a tangent line X (FIG. 2) drawn from the rearmost end position of the curved deformation portion 2 crosses the catheter tube 10. , 1 to 8 mm.

The side hole forming part 5 has a large number of side holes 4.
Is provided so as to be dense on the side surface of the portion outside the bent portion 9 of the side hole forming portion 5 of the catheter tube and to be sparse on the side surface of the opposite side (inside the bent portion 9). I have. In particular, the total area of the side holes located inside the bent portion 9 of the side hole forming portion 5 is smaller than the total area of the side holes located outside the bent portion 9 of the side hole forming portion 5. It has become something. Specifically, the total area of the side holes located inside the bent portion 9 of the side hole forming portion 5 is
About 0 to 90% of the total area of the side holes located outside the bent portion 9. In particular, it is preferably about 30 to 50%.

The side hole forming portion 5 of the catheter tube
The side hole on the side surface of the portion outside the bent portion 9 and the side hole of the outer side hole row to be described later are formed by the injection power of the contrast agent discharged from the side hole and the force applied by the injected contrast agent to the bent portion 9. Means a side hole having a component in the direction perpendicular to the axis of the side hole forming portion 5 and a component in the opposite direction. In addition, the side hole on the side surface inside the bent portion 9 of the side hole forming portion 5 of the catheter tube and the side hole of an inner side hole row to be described later receive the injection power of the contrast agent discharged from the side hole. A side hole having a component in the same direction (the same direction) as the component perpendicular to the axis of the side hole forming portion 5 in the force exerted by the contrast agent on the bent portion 9. The injection of the contrast agent is usually performed from the rear end of the catheter under the conditions of a pressure of 300 to 1200 psi and a flow rate of 5 to 15 ml / sec, so that the injection conditions within this range are almost balanced.

The side hole arrangement in the side hole forming portion 5 of the catheter of this embodiment is as shown in FIGS.
N rows (n ≧ 2, specifically 2 to 24, 6 in the illustrated example) of side hole rows are arranged at an equal angle in parallel with the central axis of the side hole forming portion. Each row has 1 to 280 pieces (12
), And the side holes of the side holes (inner side hole row) on the side adjacent to the inside of the bent portion 9 of the side hole forming portion 5 are 1 to
The number is reduced to 280 (only eight in the center row in the illustrated example). It is preferable that the number of side holes reduced increases as the area of one side hole decreases, and increases as the angle of the bent portion becomes sharper (the degree of bending increases).
The adjacent side hole rows are displaced in the axial direction so that the adjacent side holes are not located on the same circumference perpendicular to the axial direction of the side hole forming portion. By doing so, the side holes adjacent to each other on the same circumference are not located, so that the kink at the side hole portion is small. In addition, when the side hole interval in one side hole row is m, it is preferable that the side holes of adjacent side hole rows are shifted in the axial direction by m / n.

In other words, if the expression is changed, the side hole forming part 5
As shown in FIGS. 2 and 3, the bent portion 9 of the side hole forming portion 5 is formed.
The outer side hole row group (the number of side holes is 5 to 280, 12 in the illustrated example) provided in a portion outside the side in parallel with the central axis of the side hole forming portion 5, and the bent portion 9 of the side hole forming portion 5 The inner side hole row group is provided so as to face the outer side hole row group at a portion inside the hole, and the number of side holes is smaller than that of the outer side hole row group by 1 to 280 (8 in the figure, 4).
As shown in FIG. 3, the number of side holes is reduced as shown in FIG. 3, in which the distance between side holes is the same as that of the other side hole rows. 5, a side hole non-forming portion 5a extending in parallel to the axial direction is formed, and the distance between the side holes is widened and dispersed in the entire axial direction of the side hole forming portion 5, so that the side hole non-forming portion 5a is formed. Any form that is not formed may be used.
The position of the converging portion in the form in which the side hole consolidating portion is formed is preferably axially below the side hole forming portion 5 (the distal end side of the catheter tube) as shown in FIG. The central portion of the forming portion 5 or the base end of the side hole forming portion 5 may be used. In addition, by setting the side hole consolidating portion to be lower in the axial direction (toward the distal end of the catheter tube), the contrast of the apex (apex) side in left ventricle contrast enhancement is improved.

In the catheter 1, a component F1 in a direction perpendicular to the axis of the side hole forming portion 5 in the force applied to the bending portion 9 generated at the time of injection of the contrast agent shown in FIG. The sum of the component F1 and the component F2 in the same direction (the same direction) in the ejection power of the contrast agent discharged from the side hole in the portion inside the bent portion 9 is the bent portion 9 of the side hole forming portion 5.
The components F1 and F2 in the ejection power of the contrast agent ejected from the side hole outside the portion F1 are substantially balanced with the component F3 in the opposite direction.

Further, the catheter of this embodiment has a first right side surface provided in parallel with the central axis of the side hole forming portion 5 at a portion on the right side of the bent portion 9 of the side hole forming portion 5. A first row of holes (right side outer side row), a second right side side hole row (right side inner side row), and a first portion on the left side of the bent portion 9 of the side hole forming portion 5 are provided. A first left side hole row (left side inner side hole row) provided to face the right side hole row and a second second side hole row provided to face the second right side hole row. It has a left side hole row (left side outer hole row). In addition, the ejection power of the contrast agent discharged from the side holes of the right side hole row and the left side hole row corresponds to the axis of the side hole forming portion 5 due to the force applied to the bent portion 9 generated during the injection of the contrast agent. And a component in the same or opposite direction to the component F1 in the vertical direction. However, in this embodiment, the right side hole row and the left side hole row are all in the same side hole form, and the side hole forming part 5 is subjected to the force applied to the bent part 9 generated during the injection of the contrast agent. It is not used for buffering the component F1 perpendicular to the axis. However, the number of side holes in the right side inner side hole row and the left side inner side hole row is made smaller than the number of side holes in the right side outer side hole row and the left side outer side hole row, and the bending generated at the time of injection of the contrast agent. It may be used for buffering the component F1 in the direction perpendicular to the axis of the side hole forming portion 5 in the force applied to the portion 9.

As described above, in the catheter of this embodiment, the side hole forming portion 5 has a total of six side hole rows. In this embodiment, the forces F4 and F5 generated during the injection of the contrast medium shown in FIG. 8 are substantially balanced, and the first right side surface is used to prevent the catheter tip from moving in the side direction during the injection. The number of side holes in the side hole row and the first left side hole row is the same, and the number of side holes in the second right side hole row and the second left side hole row is the same. ing. The number of side hole rows is not limited to six (four side hole rows) in this embodiment, but four (no second side hole row, two side hole rows). Further, a third right side row of side holes is provided in a portion on the right side of the bent portion 9 of the side hole forming portion 5 in parallel with the central axis of the side hole forming portion 5, and further, the third right side surface A third left side hole array is provided to face the side hole array,
Eight side hole arrays (the number of side surface hole arrays is six) may be provided.

It is preferable that there are nine or more side holes 4 having an area of 0.3 mm ² or less at an arbitrary axial length of 10 mm of the side hole forming portion 5. The number of side holes is calculated by selecting a portion 10 mm having the largest number of side holes in the side hole forming portion 5. Also, 10m
It is assumed that the number of side holes applied to both ends of the m region is one. The area of the side hole 4 is 0.003 mm ^{2 to} 0.8 m
It is preferably about m ² . In particular, 0.003 mm ² ~
It is preferably about 0.3 mm ² . Furthermore, 0.008m
It is preferably set to m ² ~0.28mm ^2, more preferably 0.05mm ² ~0.25mm ^2. Also,
The hole diameter (average hole diameter) of the side holes 4 is preferably about 0.06 to 0.6 mm, more preferably 0.1 to 0.5 mm, and particularly preferably about 0.2 to 0.5 mm. . Further, it is preferable that the number of side holes at an arbitrary length of 10 mm in the axial direction of the side hole forming portion 5 is 9 to 500. In particular, 9 to 240 is preferable, and 1 is more preferable.
0 to 120. The total number of side holes is 15 to 100.
About 0 is preferable, and especially 15 to 240 is preferable.
The distance between the side holes (average distance) is 0.3 to 10 mm.
It is preferably about 0.5 to 8.0 mm.

Further, the total opening area of the side holes is 0.12 m.
m ^{2 to} 300 mm ² is preferable, and in particular,
It is preferable that the 0.45mm ² ~72mm ² about.
The total opening area of the side holes at an arbitrary axial length of 10 mm of the side hole forming portion 5 is 0.072 mm ² to 15
It is preferably about 0 mm ² , particularly 0.27 m
It is preferable to be about m ^{2 to} 70 mm ² . More preferably a 0.5mm ² ~30mm ^2, especially 2.0mm
^{2 to} 15 mm ² is preferred.

The side hole may be an ellipse or an ellipse that is long in the axial direction of the catheter tube. The side hole 4 is
Preferably, the ratio of the length of the major axis to the length of the minor axis is 1.2 or more, and the length of the minor axis is 0.06 mm or more. Further, the side hole 4 preferably has a ratio of the length of the major axis to the length of the minor axis of 1.3 or more, and the length of the minor axis is 0.2 mm or more. Further, the length of the long axis of the side hole 4 is preferably about 0.072 to 3 mm.
More preferably, it is set to about 12 to 3 mm. Further, the length of the minor axis of the side hole 4 is preferably about 0.06 to 0.9 mm, and more preferably about 0.1 to 0.5 mm. By making the shape of the side hole 4 an ellipse or an ellipse, the tensile strength of the side hole forming portion is higher than that of a catheter having a substantially circular side hole having substantially the same area. Further, as the ratio of the length of the major axis to the length of the minor axis approaches 1, the effect of improving the tensile strength of the side hole forming portion decreases, and the ratio of the length of the major axis to the length of the minor axis decreases. If it is too high (specifically, if it exceeds 50), the side hole will be weak against buckling stress.

The ellipse mentioned here is not a perfect ellipse but an ellipse including a straight line portion. The side hole 4 is provided such that the long axis is substantially parallel to the axial direction of the catheter tube. The long axis of the side hole 4 may be slightly inclined with respect to the axial direction of the catheter tube. In the case where the side hole is an ellipse or an ellipse that is long in the axial direction, the number of side holes in an arbitrary 10 mm length in the axial direction of the side hole forming portion 5 is preferably 9 to 500. Particularly, 9 to 240 is preferable, and 10 to 120 is more preferable. The total number of side holes is 15 to
About 1000 pieces are preferable, and especially 25 to 200 are preferable. The distance (average distance) between the side holes is 0.3 to 1
It is preferably about 0 mm, and more preferably about 0.5 to 8.0 mm.

The side hole is the ratio of the amount Q1 of the contrast agent ejected from the distal end opening 3 during one injection of the contrast agent and the total weight Q2 of the contrast agent ejected from each side hole. Side hole flow rate ratio = Q2 / (Q1 + Q2) is from 0.25 to 0.8
Preferably, it is formed so that In particular, the side hole flow rate ratio is preferably from 0.3 to 0.8, more preferably from 0.5 to 0.75, and most preferably from 0.6 to 0.75. In addition, the above numerical value is a viscosity of 10.6 c. p. This is the value when the contrast agent (37 ° C.) was injected from the rear end of the catheter 1 under the conditions of a total injection flow rate of 36 ml, a pressure of 1000 psi, and a flow rate of 12 ml / sec.

The method of forming the side hole is not particularly limited, and the side hole 4 can be formed by machining. However, the side hole 4 is formed by laser processing because of its excellent easiness, shape and dimensional accuracy. Is preferred. Among laser processing, processing using a laser whose oscillation wavelength is in the ultraviolet region is particularly preferable. In particular, an excimer laser is preferable. An excimer laser is a laser that oscillates a short pulse with a high peak power in the ultraviolet region, and is a rare gas (Ar, Kr, X
e) and a halogen (F, Cl, Br, etc.), for example, to oscillate at a wavelength of 193 to 351 nm.
By using such an excimer laser, small-diameter side holes 4 can be easily formed with high dimensional accuracy, with excellent workability, without the occurrence of processing defects such as deterioration, melting, burrs, and soot.

Considering the constituent materials of the catheter 1 and the like,
Among the excimer lasers, especially, the oscillation wavelength is 248n.
m or less, and a KrF having an oscillation wavelength of 248 nm.
An excimer laser or an ArF excimer laser having an oscillation wavelength of 193 nm is preferable. Those having such a wavelength are particularly excellent in workability. It is needless to say that a solid-state laser using a wavelength conversion technique and having an oscillation wavelength in an ultraviolet region can be used as the processing laser light source. A hub 7 made of a hard synthetic resin (for example, polycarbonate, polypropylene, or nylon) is attached to the proximal end of the catheter tube 10.
The hub 7 has a rear end portion to which a contrast agent injector (for example, a syringe) can be attached.

Next, the contrast catheter 20 of the embodiment shown in FIG. 5 will be described. The catheter 20 of this embodiment
Comprises a catheter tube having a lumen and a distal end opening communicating with the lumen, the catheter tube being formed at the distal end side, and being formed at the distal end portion of the catheter tube, protruding inward of the bent portion 9. And a side hole forming portion 5 provided between the bent portion 9 and the bent portion 2 and formed with a large number of side holes communicating with the lumen. A portion inside the bent portion 9 of the portion 5 is a side hole non-formed portion 5a. The difference between the catheter 20 of this embodiment and the above-described catheter 1 is only the presence or absence of an inner side hole row and the number of side holes of an outer central side hole row, and the other points are the same. And
In the catheter of this embodiment, the component of the force exerted by the injected contrast agent on the bent portion 9 in the direction perpendicular to the axis of the side hole forming portion 5 and the portion outside the bent portion 9 of the side hole forming portion 5 The component in the ejection power of the contrast agent discharged from the side hole and the component in the opposite direction are substantially balanced.

Specifically, this catheter has an outer central side hole row provided in a portion outside the bent portion 9 of the side hole forming portion 5 in parallel with the central axis of the side hole forming portion 5, Forming part 5
Has a side hole non-forming portion 5a provided to face the outer central side hole row in a portion inside the bent portion 9 of the first embodiment.
The size of the side hole non-formed portion 5a is preferably about 1/12 to 1/3 of the outer circumference of the catheter (side hole formed portion 5). More specifically, the side hole forming portion 5 of the catheter of this embodiment includes an outer central side hole row, a first right side hole row, a second right side hole row, and a first left side face. A side hole array and a second left side hole array are provided. The first and second right side hole arrays and the first and third left side hole arrays are the same as those in the above-described embodiment, and the same as in the above-described embodiment. There may be four or even eight columns.

It is preferable that the number of side holes in the outer center side hole row is about 0 to 5/6 times the number of side holes in the side side hole row. The number of side holes in the side hole row may be reduced in accordance with the decrease in the number of side holes in the outer center side hole row, but a sufficient amount of the contrast agent flowing out of the side hole is ensured to perform good contrast. Therefore, it is preferable to reduce only the number of side holes in the outer central side hole row. The area of the outer central hole row may be reduced without reducing the number of side holes in the outer central hole row.

Next, the catheter 30 of the embodiment shown in FIG.
Will be described. In the catheter 30 of this embodiment,
The side hole forming portion 5 includes an outer central side hole row provided in a portion outside the bent portion 9 of the side hole forming portion 5 in parallel with the central axis of the side hole forming portion 5, and a bending of the side hole forming portion 5. An inner central hole row is provided in a portion inside the portion 9 so as to face the outer central hole row, and has an inner hole 4a having an opening area smaller than that of the outer central hole row. The difference between the catheter 30 of this embodiment and the above-described catheter 1 is only the size of the side hole of the inner central side hole row.
Is the same. In this catheter 30, the number of side holes in the outer central hole row is the same as the number of side holes in the inner central hole row. However, the present invention is not limited to this. For example, a difference may be provided between the two such as reducing the number of inner side holes. The area of the side hole 4a in the catheter 30 is 1 / the size of the side hole 4 in the outer central side hole row.
It is preferable to be about 12 to 5/6. Furthermore, the total area of the side holes 4a is also 0 to 5/5 times the total area of the outer central side hole row.
It is preferred to be about six times.

In all of the catheters of the above-described embodiments, the side hole forming portion 5 of the catheter is located at the base end of the side hole forming portion, and the side hole opening density is higher than other portions of the side hole forming portion. A low side hole opening and low density portion may be provided. In other words, by providing a portion having physical properties intermediate between the main body 6 and the other portions of the side hole forming portion 5 at the base end of the side hole forming portion, the pushing force applied at the base portion of the catheter is reduced. It is possible to prevent kink at the boundary between the side hole forming portion 5 and the main body 6 that are easily concentrated. As a specific mode, the base end portion of the side hole forming portion 5 is a side hole reduction portion having a smaller number of side holes in the unit axial direction length than other portions, more specifically, a side hole. Simply reducing the number of side holes per unit length at the base end portion of the forming portion 5;
Further, it is conceivable that the distance between the side holes between the side hole rows at the base end portion of the side hole forming portion 5 is longer than the other portions. Furthermore, the side hole at the base end portion of the side hole forming portion 5 may have a smaller area than other portions.

[0043]

DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, specific embodiments of the present invention will be described in detail. (Example 1) A tube having an outer diameter of 1.7 mm and an inner diameter of 1.2 mm was prepared by adding a barium sulfate powder to a polymer alloy of a polyamide elastomer and a polyurethane. A tube (body-side tube) obtained by cutting this tube by about 1100 mm was prepared. In addition, a tube having an outer diameter of 1.7 mm and an inner diameter of 1.0 mm was prepared by adding barium sulfate powder to polyurethane. About 3 tubes
A tube (bending tube) cut by 3 mm was prepared. Then, a curved tube was thermally fused to the tip of the main body side tube to produce a connection tube. Then, a nylon hub was fixed to the rear end of the catheter tube. The distance between the centers of the side holes adjacent in the axial direction (the distance between the side holes arranged in the same row) is 2. from the position 38 mm proximal to the distal end of the catheter tube to the axial length of about 24 mm.
0 mm, area 0.27 mm ² (short axis 0.5
6 mm (oval with 0.7 mm long axis)
(Only one row has four side holes) at an equal angle, and a total of 64 side holes were provided.

The side holes are formed at an oscillation wavelength of 248 nm.
KrF excimer laser (power density 0.5 kW / cm ^{2 on} workpiece surface, irradiation time per side hole 2.3 sec)
This was performed by laser processing using c). Then, a portion of the curved portion of the catheter tube which is 60 mm proximal from the most distal portion of the catheter is heated, and a bent portion having an angle of 155 degrees is formed so that the side hole row having four side holes is inside. did. Further, the tube portion for bending was heated to produce a loop-shaped curved portion having a radius of curvature of about 6 mm protruding inside the bent portion, and a catheter for angiography having a shape as shown in FIG. 1 was produced. The side hole is formed on the rear end side from a position where the tangent line X drawn from the rearmost end position of the curved deforming portion is 3 mm rear end side from the position crossing the catheter tube, and the opening at the catheter tip is formed at the end of the catheter. It was almost parallel to the lumen of the main body and the side hole forming part, and was directed toward the distal end of the catheter.

The number of side holes in an arbitrary 10 mm axial direction portion (including a side hole array having four side holes) in the side hole forming portion of this catheter was 25. The total area of the side holes in an arbitrary 10 mm portion in the axial direction (portion including a side hole array having four side holes) in the side hole forming portion of this catheter was about 6.87 mm ² . The total area ratio of the side hole located inside the bent portion to the total area of the side hole located outside the bent portion of the side hole forming portion was 1/3.

(Example 2) A catheter was produced in the same manner as in Example 1 except that the conditions relating to the bent portion and the side hole were changed as follows. 3 from the tip of the catheter tube
From the position of 8 mm base end to the axial length of about 10 mm, the distance between the centers of the side holes adjacent in the axial direction (the distance between the side holes arranged in the same row) is 2.5 mm, Five rows of side holes having an area of 0.27 mm ² (an ellipse having a short axis of 0.5 mm and a long axis of 0.7 mm) were arranged in five rows (four rows, side hole row intervals of 60 degrees), and a total of 20 side holes were provided. . In the side hole forming portion, a side hole non-forming portion extending in the axial direction and having a spread of 120 degrees with respect to the axis was formed.

Then, the portion of the curved portion of the catheter tube which is 25 mm proximal from the most distal portion of the catheter is heated so that the center of the side hole non-formed portion is on the inside.
A bent portion having an angle of 155 degrees was formed. Further, the tube portion for bending was heated to form a loop-shaped curved portion having a radius of curvature of about 6 mm protruding inside the bent portion, and a catheter for angiography was prepared. The side hole is formed on the rear end side from a position where the tangent line X drawn from the rearmost end position of the curved deforming portion is 3 mm rear end side from the position crossing the catheter tube, and the opening at the catheter tip is formed at the end of the catheter. It was almost parallel to the lumen of the main body and the side hole forming part, and was directed toward the distal end of the catheter. The number of side holes in an arbitrary 10 mm portion in the axial direction (portion including a side hole array with four side holes) in the side hole forming portion of this catheter was 16 pieces. In addition, the total side hole area in an arbitrary 10 mm axial direction portion (portion including a side hole row having four side holes) in the side hole forming portion of this catheter was about 4.4 mm ² .

(Example 3) A catheter was produced in the same manner as in Example 1 except that the conditions regarding the bent portion and the side hole were changed as follows. 3 from the tip of the catheter tube
From the position of 8 mm base end side to the axial length of about 24 mm, the distance between the centers of the side holes adjacent in the axial direction (the distance between the side holes arranged in the same row) is 2.0 mm. Five rows (12 per row) of side holes having an area of 0.27 mm ² (an ellipse having a short axis of 0.5 mm and a long axis of 0.7 mm) have an area of 0.029 mm.
² (a circle with a diameter of 0.34 mm)
Are arranged at equal angles (60-degree intervals), for a total of 7 rows.
Two side holes were provided. The number of side holes in an arbitrary 10 mm axial direction portion (portion including a side hole row with four side holes) in the side hole forming portion of this catheter was 26. Also,
Arbitrary axial direction 1 in the side hole forming part of this catheter
The total area of the side holes in the 0 mm portion (the portion including the side hole row having four side holes) was about 6.32 mm ² . The total area ratio of the side hole located inside the bent portion to the total area of the side hole located outside the bent portion of the side hole forming portion was 1/3.

Example 4 A catheter was produced in the same manner as in Example 1 except that the conditions regarding the bent portion and the side hole were changed as follows. 3 from the tip of the catheter tube
From the position of 8 mm base end side to the axial length of about 24 mm, the distance between the centers of the side holes adjacent in the axial direction (the distance between the side holes arranged in the same row) is 2.0 mm. Five rows of side holes with an area of 0.27 mm ² (an ellipse with a short axis of 0.5 mm and a long axis of 0.7 mm) (12 in a row), so that the center distance between the side holes adjacent in the axial direction is 7.3 mm. And the area 0.2
A total of six rows of 7 mm ² (an ellipse having a short axis of 0.5 mm and a long axis of 0.7 mm) were arranged at an equal angle in one row (the number of side holes is 4), and a total of 64 side holes were provided. The number of side holes in the arbitrary 10 mm portion in the axial direction (portion including the side hole row with four side holes) in the side hole forming portion of this catheter was 23. The total side hole area in an arbitrary 10 mm axial direction portion (portion including four side hole rows) in the side hole forming portion of this catheter was about 6.23 mm ² . Also,
The total area ratio of the side hole located inside the bent portion to the total area of the side hole located outside the bent portion of the side hole forming portion was 1/3.

(Example 5) A catheter was produced in the same manner as in Example 1 except that the conditions regarding the bent portion and the side hole were changed as follows. 3 from the tip of the catheter tube
From the position of 8 mm base end side to the axial length of about 24 mm, the distance between the centers of the side holes adjacent in the axial direction (the distance between the side holes arranged in the same row) is 2.0 mm. Five rows of side holes with an area of 0.27 mm ² (an ellipse with a short axis of 0.5 mm and a long axis of 0.7 mm) (12 in 4 rows, 8 in one row, side hole row spacing 60 degrees) are arranged, and a total of 56 Individual side holes were provided. Note that the side hole forming portion has an axially extending and one
A side hole non-formation portion having a spread of 20 degrees was formed, and the eight side hole rows faced the center of the side hole non-formation portion.

Then, the portion of the curved portion of the catheter tube which is 60 mm proximal from the portion which is the most distal end of the catheter is heated so that the center of the side hole non-formed portion is on the inside.
A bent portion having an angle of 155 degrees was formed. Further, the tube portion for bending was heated to form a loop-shaped curved portion having a radius of curvature of about 6 mm protruding inside the bent portion, and a catheter for angiography was prepared. The side hole is formed on the rear end side from a position where the tangent line X drawn from the rearmost end position of the curved deforming portion is 3 mm rear end side from the position crossing the catheter tube, and the opening at the catheter tip is formed at the end of the catheter. It was almost parallel to the lumen of the main body and the side hole forming part, and was directed toward the distal end of the catheter. The number of side holes in an arbitrary 10 mm portion in the axial direction (portion including a side hole array with four side holes) in the side hole forming portion of this catheter was 21. The total side hole area in an arbitrary 10 mm axial direction portion (portion including a side hole row with four side holes) in the side hole forming portion of this catheter was about 5.77 mm ² .

Comparative Example A catheter was prepared in the same manner as in Example 1 except that the conditions for the bent portion and the side hole were changed as follows. 38 from the end of the catheter tube
From the position on the base end side to the axial length of about 24 mm, the distance between the centers of the side holes adjacent in the axial direction (the distance between the side holes arranged in the same row) is 2.0 mm. Six rows of side holes with an area of 0.27 mm ² (an ellipse with a short axis of 0.5 mm and a long axis of 0.7 mm) (12 in one row, side hole row spacing 60 degrees)
And a total of 72 side holes were provided. Then, a portion of the curved portion of the catheter tube that is 60 mm proximal from the most distal portion of the catheter is heated and bent at an angle of 155 degrees so that one side hole array becomes the inner central side hole array of the curved portion. Part was formed. Further, the tube portion for bending was heated to form a loop-shaped curved portion having a radius of curvature of about 6 mm protruding inside the bent portion, and a catheter for angiography was prepared. In addition, the side hole is 3 mm from the position where the tangent line X drawn from the rearmost end position of the curved deformation section crosses the catheter tube.
It was formed on the rear end side from the position on the rear end side, and the opening at the distal end of the catheter was substantially parallel to the lumen of the main body portion and the side hole forming portion of the catheter, and was directed toward the distal end of the catheter. The number of side holes in an arbitrary 10 mm axial portion of the side hole forming portion of this catheter was 26. Further, the total area of the side holes in an arbitrary 10 mm axial direction portion in the side hole forming portion of this catheter is about 7.
It was 15 mm ² .

(Experiment) Using the catheters of Examples and Comparative Examples, experiments were conducted on the dispersibility of the contrast agent, the ratio of the side hole flow rate, and the behavior of the tip of the catheter. The results were as shown in Table 1. In the experiment, the contrast agent [viscosity 10.6 c.
p. (37 ° C)], total flow rate: 36 ml, pressure: 10
The injection was performed by injecting from the rear end of the catheter under the conditions of 00 psi and flow rate: 12 ml / sec. The dispersibility test of the contrast agent was carried out under the same pseudo-contrast agent injection conditions as described above, by adding a red ink to the pseudo-contrast agent, and in a water tank, and visually assessing the state of dispersion. In Table 1, ◎ indicates very good, ○ indicates good, and × indicates bad. In the behavior of the catheter tip, ◎ indicates that there was almost no movement, ○ indicates that there was slight movement, and X indicates that there was large movement. Further, the side hole flow rate ratio is obtained by measuring the amount Q1 of the contrast agent ejected from the front end opening and the total weight Q2 of the contrast agent ejected from each side hole, and calculating the equation Q
2 / (Q1 + Q2).

[0054]

[Table 1]

[0055]

The contrast catheter of the present invention includes a lumen and a catheter tube having a distal end opening communicating with the lumen. The catheter tube has a bent portion formed on the distal side and a distal end portion of the catheter tube. A curved deformed portion that is formed and curved to protrude inward of the bent portion, and a side provided between the bent portion and the curved deformed portion, on which a plurality of side holes communicating with the lumen are formed. Having a hole forming portion, and the total area of the side holes located in a portion inside the bent portion of the side hole forming portion is a side located in a portion outside the bent portion of the side hole forming portion. It is smaller than the total area of the holes. Therefore, the component of the force applied to the bent portion by the injected contrast agent in the direction perpendicular to the axis of the side hole forming portion is a contrast component discharged from the side hole inside the bent portion of the side hole forming portion. Buffered by the difference between the component in the same direction as the component in the ejection power of the agent and the component in the direction opposite to the component in the ejection power of the contrast agent ejected from the side hole of the portion outside the bent portion of the side hole forming portion. Therefore, the behavior of the distal end of the catheter caused by the bent portion at the time of injection of the contrast agent is small, the distal end of the catheter inserted into the living body is very little separated from the target site and the deviation is small, and appropriate X-ray imaging can be performed.

The catheter of the present invention includes a lumen and a catheter tube having a distal end opening communicating with the lumen. The catheter tube has a bent portion formed on the distal end side and a distal end portion of the catheter tube. A curved deformation portion curved so as to protrude inward of the bent portion, and a side hole formed between the bent portion and the curved deformation portion and formed with a number of side holes communicating with the lumen. And a portion inside the bent portion of the side hole forming portion is a side hole non-forming portion. For this reason,
The component in the direction perpendicular to the axis of the side hole forming portion at the bent portion due to the injected contrast agent is the component in the ejection power of the contrast agent discharged from the side hole of the portion outside the bent portion of the side hole forming portion. The movement of the tip of the catheter caused by the bent portion during the injection of the contrast agent is small, the tip of the catheter inserted into the living body is very little separated from the target site, the deviation is small, and the proper X Line imaging can be performed.

[Brief description of the drawings]

FIG. 1 is a partially omitted side view of an embodiment of the contrast catheter of the present invention.

FIG. 2 is an enlarged view of a distal end portion of the catheter shown in FIG.

1. FIG. 3 is an enlarged view of the distal end portion of the catheter shown in FIG.

FIG. 4 is an enlarged sectional view of a distal end portion of the catheter shown in FIG.

FIG. 5 is an enlarged view of a distal end portion of another embodiment of the contrast catheter of the present invention.

FIG. 6 is an enlarged view of a distal end portion of another embodiment of the contrast catheter of the present invention.

FIG. 7 is an explanatory diagram for explaining the operation of the catheter of the present invention.

FIG. 8 is an explanatory diagram for explaining the operation of the catheter of the present invention.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Catheter 2 Curved deformation part 3 Tip opening 4 Side hole 5 Side hole formation part 6 Main body part 7 Hub 8 Lumen 9 Bending part 10 Catheter tube

Continued on the front page (72) Inventor Tetsu Nakagawa 1500 Inoguchi, Nakai-cho, Ashigara-gun, Kanagawa Prefecture Terumo Corporation

Claims (19)

[Claims] 1. A catheter tube having a lumen and a distal end opening communicating with the lumen, wherein the catheter tube is formed at a distal end side, and formed at a distal end portion of the catheter tube, inside the bent portion. A curved deformation portion curved to protrude in the direction, provided between the bent portion and the curved deformation portion, having a side hole forming portion formed with a number of side holes communicating with the lumen, The total area of the side holes located inside the bent portion of the side hole forming portion is smaller than the total area of the side holes located outside the bent portion of the side hole forming portion. An imaging catheter, comprising: 2. A component in a direction perpendicular to an axis of a side hole forming portion in a force applied by an injected contrast agent to a bent portion and discharged from a side hole of a portion inside the bent portion of the side hole forming portion. The sum of the component and the component in the same direction in the ejection output of the contrast agent is opposite to the component in the ejection output of the contrast agent ejected from the side hole of the portion outside the bent portion of the side hole forming portion. The imaging catheter according to claim 1, wherein the components are substantially balanced. 3. A catheter tube having a lumen and a distal end opening communicating with the lumen, wherein the catheter tube is formed at a distal end side, and formed at a distal end portion of the catheter tube, inside the bent portion. A curved deformation portion curved to protrude in the direction, provided between the bent portion and the curved deformation portion, having a side hole forming portion formed with a number of side holes communicating with the lumen, The side hole forming portion includes a component in a direction perpendicular to an axis of the side hole forming portion in a force applied by the injected contrast agent to the bent portion and a side of a portion inside the bent portion of the side hole forming portion. The sum of the component in the ejection power of the contrast agent ejected from the hole and the component in the same direction is the component in the ejection power of the contrast agent ejected from the side hole of the portion outside the bent portion of the side hole forming portion. And the component in the opposite direction is almost An imaging catheter, wherein a side hole is provided so as to be balanced. 4. The imaging catheter according to claim 1, wherein the plurality of side holes have the same side hole shape and the same opening area. 5. The side hole forming portion includes: an outer side hole row provided in a portion of the side hole forming portion outside the bent portion in parallel with a central axis of the side hole forming portion; The inner side hole row provided in the part inside the said bent part of the formation part so as to face the outer side hole row, and having a smaller number of side holes than the outer side hole row. The catheter for imaging according to item 1. 6. The side hole forming portion includes: an outer side hole row provided in a portion of the side hole forming portion outside the bent portion in parallel with a central axis of the side hole forming portion; An inner side hole row comprising a side hole having a smaller opening area than a side hole of the outer side hole row, the inner side hole row being provided so as to face the outer side hole row in a portion inside the bent portion of the forming portion. 5. The imaging catheter according to any one of 1 to 4. 7. A catheter tube having a lumen and a distal end opening communicating with the lumen, wherein the catheter tube is formed at a distal end side, and formed at a distal end portion of the catheter tube, inside the bent portion. A curved deformation portion curved to protrude in the direction, provided between the bent portion and the curved deformation portion, having a side hole forming portion formed with a number of side holes communicating with the lumen, A portion of the side hole forming portion which is inside the bent portion is a side hole non-forming portion, wherein the catheter is used for imaging. 8. A component in a direction perpendicular to an axis of the side hole forming portion in a force applied by the injected contrast agent to the bent portion and discharged from a side hole of a portion of the side hole forming portion outside the bent portion. 8. The contrast catheter according to claim 7, wherein a component in a direction opposite to the component in the ejection power of the contrast agent to be adjusted is substantially balanced. 9. A catheter tube having a lumen and a distal end opening communicating with the lumen, wherein the catheter tube is formed at a distal end side, and formed at a distal end portion of the catheter tube, inside the bent portion. A curved deformation portion curved to protrude in the direction, provided between the bent portion and the curved deformation portion, having a side hole forming portion formed with a number of side holes communicating with the lumen, The side hole forming portion includes a component in a direction perpendicular to an axis of the side hole forming portion in a force applied by the injected contrast agent to the bent portion and a side of a portion of the side hole forming portion outside the bent portion. A contrast catheter, wherein a side hole is formed such that the component in the ejection power of the contrast agent discharged from the hole and the component in the opposite direction are substantially balanced. 10. The side hole forming portion includes: an outer side hole row provided in a portion of the side hole forming portion outside the bent portion in parallel with a central axis of the side hole forming portion; 8. A side hole non-formation portion provided at a portion inside the bent portion of the formation portion so as to face the outer side hole row.
10. The imaging catheter according to any one of claims 9 to 9. 11. The imaging catheter according to claim 7, wherein the plurality of side holes have the same side hole shape and the same opening area. 12. The side hole forming portion includes: a right side surface side hole row provided in a portion of the side hole forming portion on the right side of the bent portion in parallel with a central axis of the side hole forming portion. 12. The side hole forming portion according to claim 5, further comprising a left side hole array provided at a portion on the left side of the bent portion so as to face the right side hole array. 13. Imaging catheter. 13. The imaging catheter according to claim 12, wherein the right side hole row and the left side hole row have the same number of side holes. 14. A first right side surface side provided in parallel with a central axis of the side hole forming portion at a portion of the side hole forming portion on the right side of the bent portion of the side hole forming portion. A hole array and a second right-side side hole array, and a first hole-forming portion provided on the left side of the bent portion of the side hole forming portion so as to face the first right-side side hole array. And a second left side hole array provided so as to face the left side hole array and the second right side hole array.
The catheter for imaging according to any one of the above. 15. The first right side hole row and the first right side hole row.
The number of side holes of the left side surface side hole row is the same, and the number of side holes of the second right side surface side hole row and the second left side side hole row is the same. Imaging catheter. 16. The imaging catheter according to claim 11, wherein the side holes of the right side hole row and the left side hole row have the same side hole shape and the same opening area. 17. The imaging catheter according to claim 1, wherein the distal opening of the catheter is substantially parallel to the axial direction of the main body of the catheter and faces the distal direction. 18. An arbitrary axial length 1 of the side hole forming portion.
18. The imaging catheter according to claim 1, wherein the 0 mm portion has nine or more side holes having an area of 0.8 mm ² or less. 19. The area of the side hole is 0.008 mm ²
The catheter for imaging according to any one of claims 1 to 18, which is as described above.