JP7720146B2 - Aerosol product for spraying a fixed amount of pest control fluid and method for controlling pests using the same - Google Patents

Description

The present invention relates to a pest control aerosol product for spraying a metered amount of pests in a small space having a volume of 2.0 to 18.8 ^m3 , and a pest control method using the same.

Aerosol products, which allow for the simple spraying of pest control ingredients into a treatment space, are used in a variety of applications as pest control products. For example, products that control flying pests that invade indoor spaces such as homes (see, for example, Patent Document 1) and products for treating dog and cat breeding kennels (see, for example, Patent Document 2) are known.

The aerosol product in Patent Document 1 is designed so that the residual rate of the treatment agent in the air in the treatment space is 15% or more one hour after the start of treatment, or 5% or more two hours after the start of treatment. According to Patent Document 1, by keeping the agent in the air after it is released and preventing a decrease in its airborne concentration, it is possible to maintain a sufficient extermination effect against mosquitoes hiding in the shadows.

The aerosol product in Patent Document 2 is installed at the entrance to the animal shed and sprays the entire contents. According to Patent Document 2, spraying this aerosol product toward the animal shed makes disposal easy and safe, as users are not exposed to chemicals.

Japanese Patent Application Laid-Open No. 2001-17055 Japanese Patent Application Laid-Open No. 2001-238586

The aerosol product in Patent Document 1 attempts to increase the duration of the drug's effect by adjusting the particle size of the drug that diffuses indoors, such as in a home, thereby lengthening the time the drug remains in the air. However, the aerosol product in Patent Document 1 is designed for use in an 8-tatami room, and is not necessarily designed to be suitable for use in small spaces such as tents or automobiles.

The aerosol product in Patent Document 2 requires the use of a total-discharge aerosol device, which requires time-consuming preparation before use, and is not a formulation that can be easily and frequently adopted. In particular, the use of a total-discharge aerosol device is intended for use in animal sheds where there are no dogs, cats, etc., and in small spaces where people or pets are staying, such as tents or cars, there is a higher risk of people or pets inhaling the chemicals and the irritation may be intensified. Furthermore, the aerosol product in Patent Document 2 is designed to target fleas and ticks, which are blood-sucking pests of dogs, cats, etc., and is not necessarily suitable for the purpose of exterminating flying pests such as mosquitoes.

Thus, there is a need for the development of an aerosol product that can reduce the irritation that can be a concern when used in small spaces where people and pets are present, and that can also provide sufficient control of pests, especially mosquitoes, but none of these have yet been put to practical use.

The present invention was made in consideration of the above-mentioned problems, and aims to provide a metered-dose aerosol product for pest control that can exert excellent control effects against pests, particularly mosquitoes, in small spaces while reducing the irritation felt by people and pets, and a pest control method using the same.

The characteristic configuration of the pest control metered-quantity aerosol product according to the present invention for solving the above problems is as follows:
A pest control metered dose aerosol product for controlling pests in a small space having a volume of 2.0 to 18.8 ^m3 ,
The aerosol concentrate containing a pest control component and an organic solvent and a propellant are filled in an aerosol container equipped with a metered injection valve with a single injection volume of 0.08 to 2.0 mL,
The specific gravity of the aerosol concentrate is 0.76 to 0.95;
In the aerosol container, the volume ratio (a/b) of the aerosol concentrate (a) to the propellant (b) is set to a/b ≦ 50/50 by volume, and the internal pressure is set to 0.20 to 0.60 MPa at 25°C.

The pest control metered dose aerosol product of this configuration comprises an aerosol concentrate containing a pest control ingredient and an organic solvent, and a propellant, filled in an aerosol container equipped with a metered dose valve with a single spray volume of 0.08 to 2.0 mL. Because the specific gravity, volume ratio (a/b), and internal pressure at 25°C of the aerosol concentrate are within the above-mentioned ranges, when sprayed in a narrow space with a volume of 2.0 to 18.8 ^m3 , the sprayed particles adhere to the wall surface without remaining in the air in excess. Pests, particularly mosquitoes, spend more time perched on walls and waiting for an opportunity to suck blood than they do flying, so the sprayed particles adhering to the wall surface can provide excellent mosquito control in narrow spaces. Meanwhile, because the sprayed particles do not remain in the air in excess even in narrow spaces, the irritation felt by people and pets, which can be a concern when used in narrow spaces, is reduced.

In the pest control metered dose aerosol product according to the present invention,
It is preferable that the spray amount of the control component is set to 0.2 to 20.0 mg per volume of 2.0 to 18.8 ^m3 .

According to the pest control metered-dose aerosol product of this configuration, the amount of pest control component sprayed is set to 0.2 to 20.0 mg per volume of 2.0 to 18.8 ^m3 , so that when the aerosol is sprayed in a small space, it is possible to obtain an appropriate control effect against pests, particularly mosquitoes, while reducing the irritation felt by people and pets.

In the pest control metered dose aerosol product according to the present invention,
The content of the control component in the aerosol concentrate is preferably 0.2 to 25.0 w/v %.

With this pest control metered-dose aerosol product, the content of the pest control ingredient in the aerosol concentrate is 0.2 to 25.0 w/v%, so when the aerosol is sprayed in a small space, it is possible to obtain appropriate pest control effects against pests, particularly mosquitoes, while reducing irritation to people and pets.

In the pest control metered dose aerosol product according to the present invention,
The organic solvent is preferably a lower alcohol having 2 to 3 carbon atoms.

In this pest control metered-dose aerosol product, the organic solvent is a lower alcohol with 2 to 3 carbon atoms, which helps prevent stickiness and staining on surfaces where the spray particles adhere, even in small spaces.

In the pest control metered dose aerosol product according to the present invention,
The control component preferably contains a pyrethroid compound having a vapor pressure at 30°C of 2 x 10 ^-4 to 1 x 10 ^-2 mmHg.

In the pest control metered-dose aerosol product of this configuration, the control ingredient contains a pyrethroid compound having a vapor pressure of 2 x 10 ^-4 to 1 x 10 ^-2 mmHg at 30°C, which makes it easy for the control ingredient to volatilize in small spaces where people and pets stay, which are usually kept at room temperature, and it is possible to achieve excellent control effects against pests, particularly mosquitoes.

In the pest control metered dose aerosol product according to the present invention,
The pyrethroid compound is preferably at least one selected from the group consisting of transfluthrin, metofluthrin, and profluthrin.

With this pest control metered-dose aerosol product, the pyrethroid compound is the appropriate compound described above, which allows for superior pest control effects against pests, particularly mosquitoes, in small spaces.

In the pest control metered dose aerosol product according to the present invention,
It is preferable that the spray force at a spray distance of 15 cm is set to 3.0 to 20.0 gf.

With this pest control metered-dose aerosol product, by setting the spray force at a spray distance of 15 cm to 3.0 to 20.0 gf, the spray particles reach the wall surface when sprayed in a small space, providing sufficient pest control effect against pests, particularly mosquitoes, while also reducing irritation to people and pets.

The characteristic configuration of the pest control method according to the present invention for solving the above problems is as follows:
A method for controlling pests using the above-mentioned metered dose aerosol product for pest control,
The pest control metered-quantity spray aerosol product is sprayed in a small space having a volume of 2.0 to 18.8 ^m3 .

According to this pest control method, by spraying the above-described pest control metered-dose aerosol product in a small space with a volume of 2.0 to 18.8 ^m3 , the sprayed particles can be attached to the wall surface in the small space without remaining in the air in excess. Because pests, particularly mosquitoes, spend more time perched on walls and waiting for an opportunity to suck blood than they do flying, the sprayed particles attached to the wall surface can provide excellent mosquito control in small spaces. Meanwhile, because the sprayed particles do not remain in the air in excess, the irritation felt by people and pets, which can be a concern when using the product in small spaces, can be reduced.

In the pest control method according to the present invention,
It is preferable to spray the liquid at a spray direction angle of 30 to 60 degrees with respect to the horizontal plane.

With this pest control method, spraying at a spray direction angle of 30 to 60 degrees relative to the horizontal plane can improve diffusion uniformity.

The following describes the pest control metered-dose aerosol product and pest control method of the present invention. However, the present invention is not intended to be limited to the configurations described below.

[Fixed-dose aerosol product for pest control]
The pest control metered-dose aerosol product of the present invention is a metered-dose aerosol used to control pests, particularly mosquitoes, in small spaces, and is configured by filling an aerosol concentrate containing a pest control ingredient and a solvent, as well as a propellant, into an aerosol container equipped with a metered-dose valve. Here, the term "small space" as used herein refers to a space having a volume of approximately 2.0 to 18.8 ^m3 , such as an enclosed or semi-enclosed space such as a car, tent, toilet, warehouse, storage room, garage, washroom, or entryway. More specifically, an example of a small space having a volume of 2.0 to 4.0 ^m3 is the interior of a light vehicle or compact car, and an example of a small space having a volume of 4.0 to 18.8 ^m3 is a small room measuring 1 to 4.5 tatami mats. The pest control metered-dose aerosol product of the present invention is a metered-dose aerosol, so the amount of agent sprayed is small. Furthermore, by appropriately setting the specific gravity of the aerosol concentrate, the volume ratio of the aerosol concentrate to the propellant in the aerosol container, and the internal pressure of the aerosol container at 25°C, it achieves pest control effects in small spaces and reduces the irritation felt by people and pets. In this specification, the term "control effect" refers to the control effect based on the knockdown effect and lethal effect, as well as the repellent effect. Even if the control effect is low, sufficient repellent effect can often achieve practical pest control.

<Concentrated aerosol>
The pest control component, which is one of the main components of the aerosol concentrate, contains a pyrethroid compound such as metofluthrin, profluthrin, transfluthrin, empenthrin, telallethrin, furamethrin, fenothrin, cyphenothrin, permethrin, cyfluthrin, imiprothrin, bifenthrin, fenpropathrin, tralomethrin, and etofenprox, and preferably contains a room-temperature volatile pyrethroid compound having a vapor pressure of 2×10 ⁻⁴ to 1×10 ⁻² mmHg at 30° C. Examples of room-temperature volatile pyrethroid compounds include metofluthrin, profluthrin, transfluthrin, empenthrin, telallethrin, and furamethrin, but among these, metofluthrin, profluthrin, and transfluthrin are preferred in consideration of volatility (vapor pressure), stability, basic insecticidal efficacy, and the like. The pyrethroid compounds described above can be used alone or in combination. When optical isomers based on asymmetric carbons or geometric isomers based on double bonds exist in the acid moiety or alcohol moiety of the pyrethroid compound, each of these isomers and any mixture thereof are also encompassed in the present invention.

In addition to the pyrethroid compounds mentioned above, other compounds with insecticidal activity may also be added as appropriate as control ingredients. Examples of such compounds include organosilicon compounds such as silafluofen, neonicotinoid compounds such as dinotefuran, imidacloprid, and clothianidin, and carbamate compounds such as propoxur.

From the perspective of reducing irritation to people and pets when used in small spaces, the content of the pest control ingredient in the aerosol concentrate is preferably 0.2 to 25.0 w/v%, more preferably 0.4 to 12.5 w/v%, and even more preferably 0.5 to 5.0 w/v%. If the content of the pest control ingredient in the aerosol concentrate is within the above range, when the aerosol is sprayed in a small space, it is possible to obtain an appropriate pest control effect against pests, particularly mosquitoes, while reducing irritation to people and pets.

Examples of organic solvents, which are one of the main components of aerosol concentrates, include lower alcohols with 2 to 3 carbon atoms, such as ethanol and isopropanol (IPA), hydrocarbon solvents such as normal paraffin and isoparaffin, higher fatty acid esters with 16 to 20 carbon atoms, such as isopropyl myristate (IPM), glycol ether solvents with 3 to 10 carbon atoms, and ketone solvents. Among these, lower alcohols with 2 to 3 carbon atoms are preferred because they ensure uniform dispersion of spray particles and are less likely to leave sticky or dirty floors or walls to which the spray particles adhere. The above organic solvents can be used alone or in combination, but it is preferable to use only one type of organic solvent to simplify the manufacturing process. It is also possible to mix an aqueous solvent, such as water, in addition to the organic solvent.

The specific gravity of the aerosol concentrate is set to 0.76 to 0.95, preferably 0.76 to 0.85, and more preferably 0.76 to 0.82. The specific gravity of the aerosol concentrate is an important factor affecting the settling of sprayed particles, and if the specific gravity of the aerosol concentrate is within the above range, the sprayed particles can be properly attached to the wall surface after spraying in a narrow space. Pests, particularly mosquitoes, spend more time perched on walls and waiting for an opportunity to suck blood than they do flying, so by attaching sprayed particles containing a control ingredient to the wall surface, mosquitoes can be effectively controlled in narrow spaces.

In addition to the above ingredients, the aerosol concentrate can also contain repellents, miticides, antifungal agents for mold and fungi, antibacterial agents, disinfectants, antiviral agents, fragrances, deodorizers, stabilizers, antistatic agents, defoamers, and excipients as appropriate. Repellents include DEET, ethyl butylacetylaminopropionate (IR3535), and icaridin. Miticides include methyl 5-chloro-2-trifluoromethanesulfonamidobenzoate, 3-iodo-2-propynyl butylcarbamate, amidoflumet, benzyl benzoate, phenyl salicylate, benzyl salicylate, butyl adipate, diethyl phthalate, and dibutyl phthalate. Antifungal agents, antibacterial agents, disinfectants, and antiviral agents include hinokitiol, 2-mercaptobenzothiazole, 2-(4-thiazolyl)benzimidazole, 5-chloro-2-methyl-4-isothiazolin-3-one, triforine, 3-methyl-4-isopropylphenol, and ortho-phenylphenol. Examples of fragrances include orange oil, lemon oil, lavender oil, peppermint oil, eucalyptus oil, lemon eucalyptus oil, citronella oil, lime oil, yuzu oil, jasmine oil, cypress oil, green tea essential oil, peppermint oil, menthol, p-menthane-3,8-diol, menthyl acetate, limonene, α-pinene, linalool, geraniol, phenylethyl alcohol, amyl cinnamic aldehyde, cumin aldehyde, and benzyl acetate, as well as fragrance ingredients containing leaf alcohol and leaf aldehyde, known as "green scents."

The pest control metered-dose aerosol product of the present invention can also be formulated as a water-based formulation. In this case, the amount of water contained in the aerosol concentrate is preferably 5 to 50 v/v%, and a small amount of a nonionic surfactant may be added as a solubilizing aid, as long as it does not affect the spray pattern of the spray particles. Examples of nonionic surfactants include ethers such as polyoxyethylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, and polyoxyethylene alkylamino ethers; fatty acid esters such as polyethylene glycol fatty acid esters, polyoxyethylene sorbitan fatty acid esters, and polyoxyethylene glycerin fatty acid esters; polyoxyethylene styrenated phenol; and polyalkalolamides of fatty acids.

<Propellant>
Examples of propellants used in the pest control metered-dose aerosol product of the present invention include liquefied gases such as liquefied petroleum gas (LPG), dimethyl ether (DME), and hydrofluoroolefins, as well as compressed gases such as nitrogen gas, carbon dioxide gas, nitrous oxide, and compressed air. The above propellants can be used alone or in a mixture, but propellants containing LPG as the main component are generally easy to use.

The pest control metered-dose aerosol product of the present invention comprises an aerosol concentrate containing a pest control ingredient and an organic solvent, and a propellant, filled in an aerosol container. Within the aerosol container, the volume ratio (a/b) of the aerosol concentrate (a) to the propellant (b) is set such that a/b ≦ 50/50 (0 < a/b). The volume ratio (a/b) is preferably set to 1/99 ≦ a/b ≦ 50/50, and more preferably 5/95 ≦ a/b ≦ 50/50. When the volume ratio (a/b) is within the above range, when sprayed in a narrow space, the sprayed particles adhere to the wall surface without excessively remaining in the air, allowing a sufficient amount of the pest control ingredient to adhere to the wall surface. This allows for appropriate pest control effects against pests, particularly mosquitoes, while reducing irritation to people and pets.

The pest control metered-dose aerosol product of the present invention has an internal pressure of the aerosol container set to 0.20 to 0.60 MPa at 25°C, with 0.30 to 0.50 MPa being preferred. When the internal pressure is within the above range at 25°C, a sufficient amount of the control ingredient can adhere to the wall surface when sprayed in a narrow space. If the internal pressure is less than 0.20 MPa, the spray particles tend to settle before reaching the wall surface after spraying, resulting in an insufficient amount of the control ingredient adhering to the wall surface, which may result in insufficient pest control. If the internal pressure exceeds 0.60 MPa, the spray force may be too strong, causing some of the spray particles to rebound when they reach the wall surface, potentially causing a strong irritation to people or pets when the aerosol is sprayed in a narrow space. The internal pressure of such aerosol products can be adjusted appropriately depending on the type of propellant, the vapor pressure of the propellant, and other factors. The aerosol container may be a pressure-resistant container that can withstand an internal pressure of 0.20 to 0.60 MPa, and may be made of metals such as aluminum or tinplate, synthetic resins such as polyethylene terephthalate, or pressure-resistant glass. Furthermore, if the aerosol container is made of synthetic resin, it may be translucent or transparent.

The pest control metered dose aerosol product of the present invention preferably has a spray force set to 3.0 to 20.0 gf, and more preferably 3.0 to 15.0 gf, at a distance of 15 cm from the nozzle. If the spray force is within the above range, the spray particles will reach the wall surface when sprayed in a narrow space, providing a practically sufficient effect in controlling pests, particularly mosquitoes, while also reducing irritation to people and pets.

The pest control metered dose aerosol product of the present invention is equipped with a metered dose valve for spraying a fixed amount in a narrow space, and the metered dose valve's per-spray volume is set to 0.08 to 2.0 mL, preferably 0.08 to 1.0 mL, more preferably 0.08 to 0.4 mL, and even more preferably 0.08 to 0.2 mL. When the per-spray volume is within the above range, practically sufficient control effect against pests, particularly mosquitoes, can be achieved when sprayed in a narrow space, and irritation to people and pets can also be reduced. If the per-spray volume is less than 0.08 mL, there is a risk that pests will not be sufficiently controlled in a narrow space. If the per-spray volume is more than 2.0 mL, there is a risk that the aerosol will cause a strong irritation to people and pets when sprayed in a narrow space.

In the pest control metered dose aerosol product of the present invention, the nozzle diameter of the spray element attached to the metered dose valve is preferably 0.2 to 1.0 mm. A nozzle diameter of 0.2 to 1.0 mm allows the spray force to be adjusted appropriately within a range. The shape (cross-sectional shape) of the nozzle is not particularly limited, but examples include circle, polygons such as squares, and ellipses, with circle being preferred. Here, the nozzle diameter refers to the major axis of the ellipse when the nozzle shape is elliptical, and refers to the diameter of the circumscribing circle of the polygon when the nozzle shape is polygonal.

The nozzle of the pest control metered dose aerosol product of the present invention has an elevation angle of the nozzle relative to the horizontal plane that is typically set to between 0 and 60 degrees, preferably between 10 and 60 degrees, and more preferably between 15 and 50 degrees. If the elevation angle of the nozzle relative to the horizontal plane is within the above range, spraying defects are unlikely to occur and the aerosol concentrate can be sprayed stably.

The pest control metered spray aerosol product of the present invention is preferably designed so that the spray amount of the control ingredient is 0.2 to 20.0 mg per volume of 2.0 to 18.8 ^m3 , more preferably 0.3 to 10.0 mg, and even more preferably 0.4 to 8.0 mg. When the spray amount of the control ingredient is within the above range, the mosquito control effect is appropriately exerted in a narrow space with a volume of 2.0 to 18.8 ^m3 , and it is possible to reliably knock down or kill mosquitoes while reducing irritation to people and pets. The pest control metered spray aerosol product of the present invention is preferably designed so that the spray amount of the control ingredient per spray is 0.2 to 20.0 mg, more preferably 0.3 to 10 mg. In this case, it is possible to treat a narrow space with a volume of 2.0 to 18.8 ^m3 with a single spray. Furthermore, the amount of the control component sprayed in a single spray of the pest control metered-dose aerosol product of the present invention may be set so that ^multiple sprays result in an amount of 0.2 to 20.0 mg, preferably 0.3 to 10.0 mg, of the control component per volume of 2.0 to 18.8 m3. This amount of the control component sprayed can be achieved by appropriately adjusting the composition of the aerosol concentrate, the volume ratio (a/b) of the aerosol concentrate (a) to the propellant (b), the spray volume per spray of the metered-dose spray valve, and the like, each within the above-mentioned ranges.

A single application of the pest control metered-dose aerosol product of the present invention can create an atmosphere in a small space that can control pests for approximately 3 to 24 hours.

<Pests to be controlled>
The metered dose aerosol product for pest control of the present invention is effective against cockroaches such as American cockroaches, Smoky cockroaches, and German cockroaches; bedbugs such as bedbugs (cimex), Taiwanese bedbugs (Nettite cimex); stink bugs such as brown marmorated stink bugs; ants such as Japanese wood ants, sand ants, brown ants, house ants, red fire ants, and fire ants; spiders such as huntsman spiders, spotted house spiders, and redback spiders; millipedes; centipedes such as the Japanese stag beetle; pill bugs; woodlice; termites; and Japanese white ants. In addition to crawling pests such as termites and caterpillars, it can be used to control a variety of pests, including mosquitoes such as Culex pipiens, Aedes albopictus, Aedes aegypti and Culex pipiens; flies such as house flies and flesh flies; flying pests such as small gnats, moths, chironomids, wasps and moths; clothing pests such as burrs moths and Japanese box moths; dermestid beetles such as dermestid beetles and small dermestid beetles; grain storage pests such as maize weevils; and indoor dust mites such as flour mites, house dust mites, dust mites, chigger mites and Dermatophagoides pteronyssinus. In particular, it is effective for controlling flying pests such as mosquitoes such as Culex pipiens, Aedes albopictus, Aedes aegypti, and Culex pipiens, flies such as house flies and flesh flies, small flies, moths, chironomids, wasps, and moths, and it exhibits excellent control effects against mosquitoes such as Culex pipiens, Aedes albopictus, Aedes aegypti, and Culex pipiens.

[Pest control method]
The pest control method of the present invention involves spraying the above-mentioned pest control metered dose aerosol product in a narrow space having a volume of 2.0 to 18.8 ^m3 . By using the above-mentioned pest control metered dose aerosol product, the pest control method of the present invention can exert excellent control effects against pests, particularly mosquitoes, in narrow spaces while reducing the irritation felt by people and pets that can be a concern when used in narrow spaces. In the pest control method of the present invention, when the pest control metered dose aerosol product is sprayed in a narrow space, the spray amount of the control component is preferably adjusted to 0.2 to 20.0 mg per volume of 2.0 to 18.8 ^m3 , more preferably 0.3 to 10.0 mg, and even more preferably 0.4 to 8.0 mg. When the spray amount of the control component is within the above range, when the aerosol is sprayed in a narrow space, it is possible to obtain appropriate control effects against pests, particularly mosquitoes, while reducing the irritation felt by people and pets.

In the pest control method of the present invention, the aerosol is preferably sprayed at a spray direction angle of 0 to 60 degrees relative to the horizontal plane, and more preferably at 30 to 60 degrees. If the aerosol spray direction angle is within the above range, excellent diffusion uniformity will be achieved.

To verify the effectiveness of the pest control metered-dose aerosol product of the present invention, pest control metered-dose aerosol products (Examples 1 to 17) equipped with the characteristic features of the present invention were prepared, and tests were conducted to evaluate (1) the wall adhesion of the control ingredient, (2) the irritation sensation, and (3) the effect on fabric. For comparison, pest control metered-dose aerosol products (Comparative Examples 1 to 6) not equipped with the characteristic features of the present invention were also prepared and similar tests were conducted. Furthermore, using the pest control metered-dose aerosol product of Example 1, a test was conducted to evaluate (4) its use in tents. In the following examples and comparative examples, the spray force of the pest control metered-dose aerosol product was measured using a digital force gauge (FGC-0.5, manufactured by Nidec-Shimpo Corporation).

Example 1
An aerosol concentrate was prepared by dissolving the pest control ingredient, transfluthrin (2.0 w/v%), in ethanol, an organic solvent. The specific gravity of this aerosol concentrate was 0.80. 9 mL of the aerosol concentrate (a) and 21 mL of liquefied petroleum gas (b) as a propellant were pressurized and filled into an aerosol container (pressure-resistant container) with a metered spray valve and a spray volume of 0.2 mL, so that the volume ratio (a/b) was 30/70, to obtain the pest control metered spray aerosol product of Example 1. This pest control metered spray aerosol product had an internal pressure of 0.45 MPa at 25°C and sprayed 1.2 mg of the pest control ingredient per spray. The spray force at a spray distance of 15 cm was 8.0 gf.

Comparative Example 1
The control ingredient transfluthrin (2.0 w/v%) was dissolved in ethanol, an organic solvent, to prepare 30 mL of aerosol concentrate. This aerosol concentrate had a specific gravity of 0.80. This aerosol concentrate was placed in a container equipped with a pump spray head with a single spray volume of approximately 0.2 mL, to obtain a pump spray product for pest control of Comparative Example 1. This pump spray product for pest control had a spray amount of 1.2 mg of the control ingredient per spray. The spray force at a spray distance of 15 cm was 2.0 gf.

[Examples 2 to 17, Comparative Examples 2 to 6]
Various pest control metered dose aerosol products shown in Table 1 were prepared using procedures similar to those of Example 1. Note that for the pest control metered dose aerosol products of Examples 2 to 5, 7 to 12, and 15 to 17 and Comparative Examples 2 to 4 and 6, an aerosol container with a metered dose valve and a single spray volume of 0.2 mL was used; for the pest control metered dose aerosol products of Examples 6 and 13, an aerosol container with a metered dose valve and a single spray volume of 0.4 mL was used; for the pest control metered dose aerosol product of Example 14, an aerosol container with a metered dose valve and a single spray volume of 1.0 mL was used; and for the pest control metered dose aerosol product of Comparative Example 5, an aerosol container with a metered dose valve and a single spray volume of 2.2 mL was used.

For Examples 1 to 17 and Comparative Examples 1 to 6, tests were conducted to evaluate (1) the wall adhesion of the pest control ingredient, (2) irritation, and (3) the effect on fabric. The test results are shown in Table 2.

(1) Wall adhesion of the control ingredient 20 cm x 20 cm glass plates were placed at six locations on the floor and nine locations on the walls of ^a closed small room (1.8 m wide, 1.3 m deep, 1.8 m high) with a volume of 4.2 m3. Standing in one of the four corners of the room, the test aerosol product was sprayed once from a height of 1 m above the floor toward the center of the space at a slight angle upward. 20 minutes after spraying, the glass plates placed on the floor and the wall were removed, and the adhered control ingredient was washed with acetone and analyzed by gas chromatography. Based on the obtained analytical values, the ratio of the amount of control ingredient adhered to the wall surface to the amount of control ingredient adhered to the floor surface within 20 minutes after spraying treatment was calculated to evaluate wall adhesion. The results were ranked on a three-point scale: A, B, and C, with wall adhesion being the best.

(2) Sensation of irritation: The subject stood in one of the four corners of a closed small room (1.8 m wide, 1.3 m deep, 1.8 m high) with a volume of 4.2 ^m3 , and sprayed the test aerosol product once from a height of 1 m above the floor, slightly diagonally upward toward the center of the room. After spraying, the subject waited in the room for 10 minutes, and the sensation of irritation was evaluated based on the following evaluation criteria.
(Evaluation criteria)
A: I didn't feel any irritation at all.
B: I hardly felt any irritation.
C: I felt a sense of stimulation.

(3) Effects on Fabrics In small spaces such as automobiles and tents where textile products such as seat covers and futons are installed, it is desirable that the product not only be less irritating but also have less impact on the textile products, such as stains and dirt. Therefore, the following test was conducted to simulate the effects on seat covers and futons inside automobiles and tents. A 5 cm x 5 cm polyester cloth was placed in the center of the floor of ^a closed small room (1.8 m wide, 1.3 m deep, 1.8 m high) with a volume of 4.2 m. Standing in one of the four corners of the small room, the test aerosol product was sprayed once, slightly diagonally upward from a height of 1 m above the floor, toward the center of the space. After 20 minutes had passed since spraying, the cloth was removed, and the degree of liquid staining (contamination) and stickiness was evaluated based on the following evaluation criteria.
(Evaluation criteria)
A: No liquid stains (staining) or stickiness occurred.
B: Liquid stains (staining) and stickiness were hardly observed.
C: Liquid stains (contamination) and stickiness occurred.

As a result of the tests, the pest control metered-dose aerosol products of Examples 1 to 17 were evaluated as being favorable in terms of wall adhesion of the control ingredient, irritation, and effect on fabric. This confirmed that the pest control metered-dose aerosol products of the present invention are effective in controlling mosquitoes in small spaces and reduce the irritation felt by people and pets when used in small spaces. In particular, the pest control metered-dose aerosol products of Examples 1 to 10 and 13, which had an internal pressure of 0.30 to 0.50 MPa at 25°C, a single spray volume of 0.1 to 0.4 mL, and a control ingredient content of 0.2 to 5.0 w/v%, were evaluated as being particularly favorable in terms of wall adhesion of the control ingredient and irritation. Furthermore, the pest control metered-dose aerosol products of Examples 1 to 7, 9, 11 to 14, and 17, which used ethanol as the organic solvent, caused absolutely no liquid stains (contamination) or stickiness on fabric, and were evaluated as having particularly excellent effects on fabric.

In contrast, the pump spray product of Comparative Example 1, the pest control metered dose aerosol product of Comparative Example 2, which has an internal pressure of less than 0.20 MPa at 25°C, the pest control metered dose aerosol product of Comparative Example 3, in which the specific gravity of the aerosol concentrate exceeds 0.86, and the pest control metered dose aerosol product of Comparative Example 6, in which the volume ratio (a/b) of the aerosol concentrate to the propellant is less than 50/50, showed poor wall adhesion of the control ingredient in narrow spaces. For this reason, it is believed that the pump spray product of Comparative Example 1 and Comparative Examples 2, 3, and 6 are not sufficiently effective in controlling pests in narrow spaces.

The pest control metered-dose aerosol product of Comparative Example 4, which had an internal pressure of more than 0.60 MPa at 25°C, and the pest control metered-dose aerosol product of Comparative Example 5, which had a spray volume of more than 1.0 mL, caused an irritating sensation when used in small spaces and were not preferable.

(4) Use in a tent A futon was placed in a tent with a volume of 12 ^m3 (area 8 ^m2 , height 1.5 m), and the pest control metered dose aerosol product of Example 1 was sprayed three times from the entrance at 9:00 PM in the summer, after which the subject went to sleep. The subject woke up at 8:00 AM the next day, but was not bitten by any mosquitoes in the tent during this time. In other words, mosquito control was achieved for more than 10 hours. Furthermore, the subject did not experience any irritation such as choking while staying in the tent, and was able to spend the time comfortably. No stains or dirt were found on the futon.

The pest control metered-dose aerosol product and pest control method of the present invention can be used to control pests, particularly mosquitoes, in small spaces such as automobiles and tents.

Claims (8)

A pest control metered dose aerosol product for controlling pests in a small space with a volume of 2.0 to 12 ^m3 ,
the pest is a mosquito,
The aerosol concentrate containing a pest control component and an organic solvent and a propellant are filled in an aerosol container equipped with a metered injection valve with a single injection volume of 0.08 to 2.0 mL,
the control component contains only a pyrethroid compound having a vapor pressure of 2×10 ⁻⁴ to 1×10 ⁻² mmHg at 30°C;
The specific gravity of the aerosol concentrate is 0.76 to 0.95;
The aerosol product for controlling pests in a metered dose is configured such that the volume ratio (a/b) of the aerosol concentrate (a) to the propellant (b) in the aerosol container is a/b ≦ 50/50 by volume, and the internal pressure is 0.20 to 0.60 MPa at 25°C. A pest control metered dose aerosol product for controlling pests in a small space with a volume of 2.0 to 12 ^m3 ,
The aerosol concentrate containing the pest control component and the organic solvent and the propellant are filled in an aerosol container equipped with a metered injection valve with a single injection volume of 0.08 to 0.2 mL,
the control component contains only a pyrethroid compound having a vapor pressure of 2×10 ⁻⁴ to 1×10 ⁻² mmHg at 30°C;
The specific gravity of the aerosol concentrate is 0.76 to 0.95;
The aerosol product for controlling pests in a metered dose is configured such that the volume ratio (a/b) of the aerosol concentrate (a) to the propellant (b) in the aerosol container is a/b ≦ 50/50 by volume, and the internal pressure is 0.20 to 0.60 MPa at 25°C . 3. The pest control metered spray aerosol product according to claim 1, wherein the content of the control component in the aerosol concentrate is 0.2 to 25.0 w/v %. 4. The pest control metered-dose aerosol product according to claim 1 , wherein the organic solvent is a lower alcohol having 2 to 3 carbon atoms. The pest control metered dose aerosol product according to any one of claims 1 to 4 , wherein the pyrethroid compound is at least one selected from the group consisting of transfluthrin, metofluthrin, and profluthrin. 6. The pest control metered dose aerosol product according to claim 1, wherein the spray force at a spray distance of 15 cm is set to 3.0 to 20.0 gf. A method for controlling pests using the metered dose aerosol product for pest control according to any one of claims 1 to 6 ,
A method for controlling pests, comprising spraying the pest control metered-quantity spray aerosol product in a small space having a volume of 2.0 to 12 ^m3 . 8. The method for controlling insect pests according to claim 7 , wherein the spray direction angle is 30 to 60 degrees relative to the horizontal plane.