JP6811622B2 - Film for moisture absorption and gas adsorption and laminate for packaging - Google Patents

Description

The present invention relates to films for moisture absorption and gas adsorption and laminates for packaging.

Conventionally, in the fields of foods, pharmaceuticals, electronic parts, precision machinery, recording materials, etc., a method of including a desiccant has been adopted for the purpose of preventing quality deterioration due to moisture. Further, in order to give the packaging material itself a hygroscopic function without putting a separate desiccant in the packaging, the desiccant is contained in the packaging material itself.

For example, Patent Document 1 discloses a desiccant film using a desiccant-containing resin containing a molecular sieve and a resin having an MFR of 10 or more.

In addition, depending on the contents, there are those that release volatile organic gas or inorganic gas called outgas. If this outgas has an odor, the odor diffuses when opened, which may cause discomfort to the user. Therefore, in order to reduce the outgas in the packaging, a gas absorbent is contained in the packaging material itself.

For example, Patent Document 2 discloses a PTP (press-through package) blister film having an adsorption layer containing hydrophobic zeolite as a deodorant.

Japanese Unexamined Patent Publication No. 2005-280188 Japanese Unexamined Patent Publication No. 2006-334819

If there is a lot of water in the package, the outgas, which is an odor component, may stay without being dispersed, and as a result, the odor may be strongly felt. In addition, the contents packaged by moisture are hydrolyzed to generate outgas, which may make it easier to feel a strong odor. Therefore, in order to effectively remove the odor in the package, it is desirable not only to remove the outgas but also to remove the water in the package.

Further, depending on the contents to be packaged, there are some that generate a large amount of outgas, so it may be necessary to increase the amount of outgas adsorbed. In this case, if the content of the gas adsorbent is increased, the amount of outgas adsorbed can be increased, but considering the moldability and cost of the packaging material, it is preferable to increase the content of the gas adsorbent. Sometimes not.

Therefore, there is a need to provide a film for moisture absorption and gas adsorption that has a moisture absorption function and can absorb a larger amount of outgas even with a small amount of gas adsorbent.

As a result of diligent studies, the present inventors have found that the above problems can be solved by the following means, and have completed the present invention. That is, the present invention is as follows:
<1> It has an absorbent layer containing a thermoplastic resin and a chemical absorbent and a hydrophobic physical adsorbent dispersed in the thermoplastic resin, and the equilibrium humidity of the hydrophobic physical adsorbent is high. , 35% RH or more,
Film for moisture absorption and gas adsorption.
<2> The film for moisture absorption, moisture absorption and gas adsorption according to the above item <1>, wherein the equilibrium humidity of the chemical absorbent is 35% RH or less.
<3> The film for moisture absorption and gas adsorption according to the above <1> or <2>, wherein the total content of the chemical absorbent and the hydrophobic physical adsorbent is 70% by mass or less.
<4> The film for moisture absorption and gas adsorption according to any one of the above items <1> to <3>, further comprising a skin layer on one or both surfaces of the absorption layer.
<5> In any one of the above items <1> to <4>, the chemical absorbent is selected from the group consisting of calcium oxide, calcium chloride, calcium sulfate, magnesium sulfate, sodium sulfate and a mixture thereof. The film for absorbing moisture and adsorbing gas.
<6> The moisture absorption and gas adsorption according to any one of the above items <1> to <5>, wherein the physical adsorbent is selected from the group consisting of hydrophobic zeolite, activated carbon, mesoporous substances and mixtures thereof. Film for.
<7> A packaging laminate comprising the moisture-absorbing and gas-adsorbing film according to any one of the above items <1> to <6> and a base material layer.
<8> The packaging laminate according to item <7>, wherein the base material layer includes a barrier layer and a resin layer.
<9> The film for moisture absorption and gas adsorption of the packaging laminate according to the above <7> or <8>, and the packaging laminate is provided with one or a plurality of the packaging laminates. A portion of the side is bag-shaped by being heat-sealed with another portion of this laminate or another film.
Packaging bag.
<10> A packaging bag containing the contents and the packaging bag according to the above item <9>, which contains the contents and the contents.
<11> The packaging laminate according to the above <7> or <8>, which is a blister pack laminate.
<12> A blister pack comprising the packaging laminate according to the above item <11>, which has a pocket portion for storing the contents, and a lid material laminated on the packaging laminate.
<13> A blister pack containing the contents and the blister pack according to the above item <12>, which contains the contents and the above contents.

According to the present invention, it is possible to provide a film for absorbing moisture and adsorbing gas, which has a moisture absorbing function and can absorb a large amount of outgas.

FIG. 1 is an example of a layer structure of the packaging laminate of the present invention. FIG. 2 is a diagram showing an evaluation result of equilibrium humidity.

<< Film for moisture absorption and gas adsorption >>
The moisture-absorbing and gas-adsorbing film of the present invention has a thermoplastic resin and an absorbing layer containing a chemical absorbent and a hydrophobic physical adsorbent dispersed in the thermoplastic resin. The equilibrium humidity of the hydrophobic physical adsorbent is 35% RH or more.

Here, the "equilibrium humidity" of the chemical absorber or the hydrophobic physical adsorbent refers to the chemical absorbent or the hydrophobicity of the film containing the chemical absorbent or the hydrophobic physical adsorbent with respect to the moisture in the closed container. The amount of the physical adsorbent should be excessive, that is, the amount of the chemical absorbent or the hydrophobic physical adsorbent should be such that the humidity in the closed container can be reduced to 0% RH (relative humidity). It is the relative humidity in the closed space in an equilibrium state when left in the closed space in an environment of 23 ° C. and 55% RH. This equilibrium humidity was determined by, for example, adding 20% by mass of a chemical absorbent or a hydrophobic physical adsorbent to low density polyethylene to obtain a film having a thickness of 100 μm, and then cutting the film to a size of 5 cm × 5 cm and then cutting the film. It can be measured by leaving one or two films in a 140 mL enclosed space in an environment of 23 ° C. and 55% RH for 24 hours.

The specific equilibrium humidity of the chemical absorbent and the physical adsorbent is shown with reference to FIG. In FIG. 2, a film having a thickness of 100 μm is obtained by heating and kneading 20% by mass of a chemical absorber or a physical adsorbent and 80% by mass of low-density polyethylene with a kneader, and then heating and kneading the obtained resin composition with a hot press machine. Was cut into 5 x 5 cm squares, and this and a temperature / humidity logger (Hygrocron, KN Laboratories Co., Ltd.) were placed in a 140 mL glass bottle with air at 23 ° C and 55% RH and sealed. It is stored in the environment for one day, and the humidity inside the bottle is measured over time.

With reference to FIG. 2, the equilibrium humidity of calcium oxide, which is a chemical absorbent in the present invention, is less than 35% RH, whereas hydrophobic zeolite, mesoporous, which is a hydrophobic physical adsorbent in the present invention. It can be seen that the equilibrium humidity of silica, activated carbon, and peanut shells (powder) exceeds 35% RH.

The present inventors have found that a film for moisture absorption and gas adsorption having the above-mentioned structure can absorb a large amount of outgas while having a moisture absorption function.

Although not bound by theory, this is due to the rapid absorption of outgas by the hydrophobic physisorbent described above, which suppresses the rapid deactivation of the chemical absorbent, thereby the gas absorption capacity of the chemical absorbent. That is, the absorption behavior of the chemical absorbent and the hydrophobic physical adsorbent, that is, the relationship between the partial pressure of outgas and the absorption rate in the enclosed space is different from each other. It is considered that it is due to the interaction with.

Hereinafter, each component of the present invention will be described.

<Absorption layer>
The absorbent layer is an absorbent layer containing a thermoplastic resin, a chemical absorbent and a hydrophobic physical adsorbent. Here, in the present specification, the term "absorption" should be understood to include not only chemical absorption caused by a chemical reaction but also physical adsorption.

Further, the absorption layer may further include an optional skin layer. The skin layer may be present on one or both surfaces of the absorbent layer.

The total content of the chemical absorbent and the hydrophobic physical adsorbent in the absorption layer can be more than 0% by mass, 5% by mass or more, 10% by mass or more, or 15% by mass or more, and 70% by mass. Hereinafter, it can be 50% by mass or less, or 40% by mass or less.

The mass ratio of the chemical absorbent to the hydrophobic physical adsorbent can be 0.1 or greater, 0.2 or greater, and 9.0 or lower, 7.0 or lower, or 5.0 or lower. it can. In order to improve the dispersibility of the chemical absorbent and the hydrophobic physical adsorbent in the absorption layer, the mass ratio of the chemical absorbent to the hydrophobic physical adsorbent should be 0.3 or more, or 0.6. The above is preferably 4.0 or less, 3.0 or less, or 1.5 or less.

The thickness of the absorption layer can be 5 μm or more, 10 μm or more, 20 μm or more, or 30 μm or more, and can be 200 μm or less, 180 μm or less, 160 μm or less, 140 μm or less, 120 μm or less, or 100 μm or less.

{Thermoplastic resin}
As the thermoplastic resin, a thermoplastic resin having high permeability of water and outgas and excellent kneadability can be used. As such a thermoplastic resin, at least one selected from, for example, polyolefin, vinyl polymer, polyester, ionomer, polycarbonate, polyamide, thermoplastic elastomer and the like, or a combination thereof can be used.

Examples of the polyolefin include polyethylene-based resin and polypropylene-based resin.

In the present specification, the polyethylene-based resin contains a repeating unit of an ethylene group in the main chain of the polymer in an amount of 30 mol% or more, 40 mol% or more, 50 mol% or more, 60 mol% or more, 70 mol% or more, or 80 mol% or more. Resins, such as low density polyethylene (LDPE), linear low density polyethylene (LLDPE), medium density polyethylene (MDPE), high density polyethylene (HDPE), ethylene-acrylic acid copolymer (EAA), ethylene- Methacrylate copolymer (EMAA), ethylene-ethyl acrylate copolymer (EEA), ethylene-methyl acrylate copolymer (EMA), ethylene vinyl acetate copolymer (EVA), carboxylic acid-modified polyethylene, carboxylic acid-modified ethylene It is selected from the group consisting of vinyl acetate copolymers, derivatives thereof, and mixtures thereof.

In the present specification, the polypropylene resin is a resin containing 30 mol% or more, 40 mol% or more, 50 mol% or more, 60 mol% or more, 70 mol% or more, or 80 mol% or more of repeating units of propylene groups in the main chain of the polymer. Yes, for example, polypropylene (PP) homopolymers, random polypropylene (random PP), block polypropylene (block PP), chlorinated polypropylene, carboxylic acid-modified polypropylene, derivatives thereof, and mixtures thereof.

Examples of the vinyl polymer include PVC (polyvinyl chloride), polystyrene and the like.

Examples of the polyester include PET (polyethylene terephthalate) and polybutylene terephthalate.

Examples of the ionomer include a resin obtained by cross-linking a copolymer of ethylene and methacrylic acid with a metal such as zinc.

Examples of the polycarbonate include a resin obtained by condensation polymerization of bisphenol A and carbonyl chloride.

Examples of the polyamide include nylon such as nylon (registered trademark) 6 and nylon MXD6.

Examples of the thermoplastic elastomer include styrene-butadiene rubber and ethylene-propylene rubber.

{Chemical absorbent}
The chemical absorbent is a chemical absorbent dispersed in a thermoplastic resin.

In particular, the equilibrium humidity of the chemical absorbent can be 35% RH or less, 33% RH or less, or 30% RH or less, and 5% RH or more, 13% RH or more, or 15% RH or more. Can be done. When the equilibrium humidity of the chemical absorbent is within the above range, the chemical absorbent can have a role as a hygroscopic agent capable of preferentially absorbing water.

Examples of the chemical absorbent include calcium oxide, calcium chloride, calcium sulfate, magnesium sulfate, sodium sulfate and the like. These chemical absorbents may be used alone or as a mixture.

The average particle size of the chemical absorber (particle size at an integrated value of 50% in the particle size distribution obtained by the laser diffraction / scattering method) can be 1 μm or more, 3 μm or more, or 5 μm or more, and 50 μm or less, 40 μm. It can be less than or equal to 30 μm or less.

{Hydrophobic physical adsorbent}
The hydrophobic physical adsorbent is a physical adsorbent dispersed in a thermoplastic resin and having an equilibrium humidity of 35% RH or more.

This equilibrium humidity can be 35% RH or higher, 38% RH or higher, or 40% RH or higher, and can be 50% RH or lower, 48% RH or lower, or 45% RH or lower. When the equilibrium humidity of the hydrophobic physical adsorbent is within the above range, the hydrophobic physical adsorbent can have a role as a gas adsorbent capable of preferentially adsorbing outgas.

Here, the outgas is a volatile organic gas or an inorganic gas (excluding water vapor) released from the contents or the like stored in the package. Specifically, examples of outgas include aromatic compounds such as benzene and toluene, esters such as ethyl acetate, aliphatic hydrocarbons such as methane and ethane, alcohols such as ethanol, aldehydes such as acetaldehyde, and isobutylamine. Examples include amines. Such outgassing may not only be unpleasant with respect to odor, but may also adversely affect the contents.

Examples of the hydrophobic physical adsorbent include hydrophobic zeolite, silica gel, hydrophobically treated silica gel, mesoporous substances, activated carbon, and plant shell powder. The mesoporous substance is a substance having a pore diameter intermediate between micropores (2 nm or less) and macropores (50 nm or more), and examples thereof include mesoporous silica. As the plant shell powder, a powder obtained by finely crushing a porous peanut shell can be used. These hydrophobic physical adsorbents may be used alone or as a mixture.

In the present specification, the hydrophobic zeolite is a zeolite having a Si / Al molar ratio of more than 1.5. The Si / Al molar ratio can be more than 1.5, 2.0 or more, 5.0 or more, 10.0 or more, 30.0 or more, 50.0 or more, or 100.0 or more. Zeolites having a Si / Al molar ratio within the above range can have an equilibrium humidity of 35% RH or more, thereby having a role as a gas adsorbent capable of preferentially adsorbing outgas.

As such hydrophobic zeolite, for example, beta type, ZSM-5 type, ferrienite type, mordenite type, L type, or Y type zeolite can be used. Further, ZSM-11, which is an analog of ZSM-5 type zeolite, silicalite, silicalite-2, and pentasil type metallosilicate can also be used. These may be used alone or in combination.

The average particle size of the hydrophobic physical adsorbent (particle size at an integrated value of 50% in the particle size distribution obtained by the laser diffraction / scattering method) can be 1 μm or more, 3 μm or more, or 5 μm or more, and 50 μm or less. , 40 μm or less, or 30 μm or less.

{Skin layer}
The skin layer prevents the chemical absorbent and the hydrophobic physical adsorbent contained in the absorbent layer from falling off, and has strength as a packaging container, for example, tensile fracture strength and heat seal strength with other films and laminates. It is an optional layer laminated on one or both surfaces of the absorption layer.

The skin layer can be made of a thermoplastic resin to improve film formation stability and / or prevent the chemical absorbent and / or hydrophobic physical adsorbent from falling off or coming into direct contact with the outside. / Or surface smoothness to be laminated with the base material layer can be imparted.

As the thermoplastic resin constituting the skin layer, the above-mentioned thermoplastic resin can be used. When skin layers are laminated on both sides of the absorption layer, the thermoplastic resins constituting the skin layers may be the same or different.

The thickness of the skin layer can be 1 μm or more, 3 μm or more, 5 μm or more, or 7 μm or more, and can be 50 μm or less, 40 μm or less, 30 μm or less, 20 μm or less, or 15 μm or less. When skin layers are laminated on both sides of the absorption layer, the thickness of these skin layers may be the same or different.

<< Laminate for packaging >>
As shown in FIG. 1A, the packaging laminate (100) of the present invention includes the above-mentioned moisture absorbing and gas adsorbing film (10) and a base material layer (20).

<Base layer>
The base material layer may be, for example, a resin layer, a barrier layer, or a laminate thereof.

The base material layer may be laminated on a film for absorbing moisture and adsorbing gas. More specifically, the base material layer may be laminated on the moisture absorbing and gas adsorbing film directly or via another layer.

{Resin layer}
As the resin layer, a thermoplastic resin having excellent impact resistance, abrasion resistance, etc., for example, polyolefin, vinyl polymer, polyester, polyamide, etc. can be used alone or in combination of two or more in a plurality of layers. .. This resin layer may be a stretched film or a non-stretched film.

As the polyolefin, in addition to the polyethylene-based resin and polypropylene-based resin mentioned for the absorption layer, a copolymer of ethylene and an oxygen-containing ethylenically unsaturated monomer and the like can be used. Examples of the copolymer of ethylene and the oxygen-containing ethylenically unsaturated monomer include EVOH (ethylene-vinyl alcohol copolymer) and the like.

As the vinyl polymer, PVDC (polyvinylidene chloride), polychlorotrifluoroethylene, PAN (polyacrylonitrile) and the like can be used in addition to the vinyl polymers mentioned for the absorption layer.

As the polyester and polyamide, the polyester and polyamide mentioned for the absorption layer can be used.

The thickness of the resin layer can be 3 μm or more, 5 μm or more, 7 μm or more, 10 μm or more, or 12 μm or more, and 120 μm or less, 100 μm or less, 80 μm or less, 60 μm or less, 50 μm or less, 40 μm or less, 30 μm or less, Alternatively, it can be 20 μm or less.

{Barrier layer}
As the barrier layer, a material capable of suppressing the permeation of moisture from the outside into the absorption layer can be used. A barrier layer is not required when the resin layer has sufficient water vapor barrier properties and gas barrier properties, but it is preferable to provide a barrier layer when the resin layer does not have sufficient barrier properties. For example, but not limited to this, a metal foil such as an aluminum foil or an aluminum alloy, an aluminum vapor deposition film, a silica vapor deposition film, an alumina vapor deposition film, an inorganic vapor deposition film such as a silica-alumina dual vapor deposition film, or polyvinylidene chloride. An organic coating film such as a coating film or a polyvinylidene fluoride coating film can be used.

The thickness of the barrier layer can be 1 μm or more, 3 μm or more, 5 μm or more, or 7 μm or more, and must be 70 μm or less, 60 μm or less, 50 μm or less, 40 μm or less, 30 μm or less, 20 μm or less, or 10 μm or less. Can be done.

<Other layers>
The packaging laminate of the present invention may include another layer, for example, an adhesive layer, between each layer. As the adhesive layer, for example, a dry laminate adhesive, a hot melt adhesive, a water-soluble adhesive, an emulsion adhesive, a thermoplastic resin for extrusion lamination and the like can be used.

<< Laminated body for blister pack >>
As shown in FIG. 1 (b), the blister pack laminate (200) may include the above-mentioned film for moisture absorption and gas adsorption (10), a reinforcing layer (30), and a base material layer (20). it can.

<Reinforcement layer>
As the reinforcing layer (30), at least one selected from high-density polyethylene, PVC (polyvinyl chloride), polypropylene, PET (polyethylene terephthalate), and polyamide, or a combination thereof can be used.

Examples of the polyamide include the polyamides mentioned for the binder resin.

The thickness of the reinforcing layer for use in the blister pack laminate is preferably 12 μm or more, 15 μm or more, or 20 μm or more from the viewpoint of imparting appropriate elasticity to the laminate, and maintains appropriate moldability. From the viewpoint of the above, it is preferably 60 μm or less, 55 μm or less, or 50 μm or less.

<Base layer>
The base material layer may be, for example, a resin layer, a barrier layer, or a laminate thereof.

(Resin layer)
As the resin layer, the resin mentioned above can be used, but a non-stretched film is preferable from the viewpoint of imparting moldability of the pocket.

The thickness of the resin layer can be the thickness mentioned above, but from the viewpoint of imparting appropriate elasticity to the blister pack laminate, it is preferably 12 μm or more, 13 μm or more, or 15 μm or more. Further, from the viewpoint of maintaining appropriate moldability, it is preferably 25 μm or less, 22 μm or less, or 20 μm or less.

(Barrier layer)
As the barrier layer, the barrier layer mentioned above can be used, but it is preferable to use a metal foil such as an aluminum foil or an aluminum alloy. Similar to the above, when the resin layer has sufficient water vapor barrier property and gas barrier property, the barrier layer is not necessary, but when the resin layer does not have sufficient barrier property, it is preferable to provide the barrier layer. ..

The thickness of the barrier layer can be the thickness mentioned above, but is preferably 7 μm or more, 10 μm or more, or 15 μm or more from the viewpoint of imparting appropriate elasticity to the blister pack laminate. Further, from the viewpoint of maintaining appropriate moldability, it is preferably 45 μm or less, 40 μm or less, or 35 μm or less.

<Other layers>
The blister pack laminate of the present invention may include another layer, for example, an adhesive layer, between each layer. As the adhesive layer, the adhesive layer mentioned for the packaging laminate can be used.

《Packaging bag》
The packaging bag of the present invention includes one or a plurality of the above-mentioned packaging laminates, and a part of the one or a plurality of packaging laminates on the film side for moisture absorption and gas adsorption is the laminate. It is bag-shaped by being heat-sealed with other parts or other films. Here, the other film may be another packaging laminate, or may be another film other than the packaging laminate.

The packaging bag of the present invention can be a packaging bag containing contents that stores the contents.

<Contents>
The contents are not limited as long as they can be deteriorated by contact with the outside air, and include foods, cosmetics, medical instruments, medical devices, electronic parts, precision machines, recording materials, etc. in addition to drugs. Can be done. In addition to pharmaceutical preparations, drugs include cleaning agents, pesticides and the like.

<< Manufacturing method of packaging bag >>
The method for producing a packaging bag of the present invention includes the following steps:
A process of melt-kneading a thermoplastic resin, a chemical absorbent, and a hydrophobic physisorbent to prepare a masterbatch.
A process of forming a masterbatch film to produce a film for moisture absorption and gas adsorption,
A step of laminating a base material layer on a film for moisture absorption and gas adsorption to prepare a laminate for packaging, and a part of the film for moisture absorption and gas adsorption of the packaging laminate to another part or other part of this laminate. The process of heat-sealing with the film to make it into a bag.

The masterbatch can be prepared by melt-kneading a thermoplastic resin, a chemical absorbent, and a hydrophobic physical adsorbent. As the thermoplastic resin, the resins mentioned for the absorption layer can be used. The melt kneading can be carried out by using, for example, a batch type kneader such as a kneader, a Henschel mixer, a mixing roll, or a continuous kneader such as a twin-screw kneader.

<Process for producing a film for moisture absorption and gas adsorption>
The film for moisture absorption and gas adsorption can be produced by forming the above masterbatch. The film forming method is not limited to this, and examples thereof include an inflation method, a T-die method, a calendar method, a casting method, press molding, extrusion molding, and injection molding. When the absorption layer has a skin layer, a master batch for the skin layer can be prepared separately, and a film can be formed by a coextrusion inflation method, a coextrusion T-die method, or the like.

<Process for producing a laminate for packaging>
The packaging laminate can be produced by laminating a base material layer on a film for moisture absorption and gas adsorption. The laminating method is not limited to this, and examples thereof include an extrusion laminating method and a dry laminating method. Preferably, an extrusion laminating method is used.

<Process to make a bag>
The bag-shaped step can be performed by heat-sealing a part of the packaging laminate on the film side for moisture absorption and gas adsorption with another portion of the laminate or another film. Here, the other film may be another packaging laminate, or may be another film other than the packaging laminate.

Examples of the form of the packaging bag include a three-way seal bag, a four-way seal bag, a gusset bag, a bottom gusset bag, a stand bag, a bottom seal bag, and a tetrahedral bag.

《Blister pack》
The blister pack of the present invention includes the above-mentioned packaging laminate, particularly a packaging laminate for a blister pack, and a lid material. This packaging laminate has pockets for storing the contents.

In the use of this blister pack, the contents can be taken out by pushing the pocket portion from the blister pack side and breaking through the lid material. When the same resin as the film for moisture absorption and gas adsorption of the blister pack laminate is used as the resin layer contained in the lid material, the contents are taken out by peeling the lid material by cohesive failure. You can also. Further, when an easy peel resin or an easy peel film is used as the resin layer contained in the lid material, the contents can be taken out by peeling the lid material at the bonding interface between the blister pack and the lid material.

<Lid material>
The lid material includes, for example, a lid material resin layer and a metal layer.

The lid material may be adhered to the packaging laminate. More specifically, the lid material may be adhered to the packaging laminate directly or via another layer.

(Lid material resin layer)
The lid material resin layer is arranged inside the blister pack of the metal layer, and is a layer capable of sealing the blister pack by adhering to a film for moisture absorption and gas adsorption of the packaging laminate having pockets formed therein. Is. As the resin layer, a thermoplastic resin can be used. Examples of the thermoplastic resin include the thermoplastic resins mentioned for the absorption layer, and the resin layer of the lid material and the moisture absorption and gas adsorption film of the above-mentioned packaging laminate are the same resin from the viewpoint of enhancing the adhesiveness. Can be included.

Further, as the resin layer, an easy peel resin such as a polyolefin-based polymer alloy or an easy peel film can also be used.

(Metal layer)
The metal layer is a layer that can impart a barrier property to the lid material and prevent moisture, organic gas, inorganic gas, etc. from entering the pocket portion of the blister pack from the outside. As the metal layer, for example, an aluminum foil such as a pure aluminum foil or an aluminum alloy foil can be used.

<Pocket part>
The pocket portion can have an arbitrary shape, for example, a dome shape, according to the contents to be stored in the blister pack.

<Contents>
Examples of the contents of the blister pack include pharmaceutical products.

《Manufacturing method of blister pack》
The method for producing a blister pack of the present invention includes the following steps:
A process of melt-kneading a thermoplastic resin, a chemical absorbent, and a hydrophobic physisorbent to prepare a masterbatch.
A process of forming a masterbatch film to produce a film for moisture absorption and gas adsorption,
A process of laminating an optional reinforcing layer and a base material layer on a film for moisture absorption and gas adsorption to prepare a laminate for packaging.
A step of forming a pocket portion in the packaging laminate by pressing the packaging laminate, and a step of laminating a lid material on the packaging laminate having the pocket portion.

<Process for making a masterbatch>
The masterbatch can be produced by the method described for the method for producing a packaging bag.

<Process for producing a laminate for packaging>
The packaging laminate can be produced by laminating a reinforcing layer and a base material layer on a film for absorbing moisture and adsorbing gas, and aging the film as desired. As the laminating method, the method described for the manufacturing method of the packaging bag can be used.

<Process of forming pockets>
The step of forming the pocket portion can be performed by pressing the packaging laminate by, for example, a flat plate type pneumatic molding method, a plug assisted pneumatic molding method, a drum type vacuum forming method, a plug molding method, or the like.

<Process of laminating lid materials>
The lid material may be laminated by heat sealing or via an adhesive layer.

The present invention will be specifically described with reference to Examples and Comparative Examples, but the present invention is not limited thereto.

<< Production of evaluation film >>
<Example 1>
10% by mass of calcium oxide (CaO, Wako Pure Chemical Industries, Ltd.) as a chemical absorber, 10% by mass of hydrophobic zeolite (ABSCENTS3000, Union Showa Co., Ltd.) as a hydrophobic physical adsorbent, and thermoplastic resin pellets (ABSCENTS3000, Union Showa Co., Ltd.) Low-density polyethylene, Petrosen 202, Toso Co., Ltd.) 80% by mass is dry-blended, heated and kneaded at 150 ° C with a kneader, the obtained resin composition is crushed, and heated at 150 ° C with a hot press. By forming the film, a film of Example 1 having an absorption layer having a thickness of 100 μm was obtained.

<Examples 2 and 3 and Comparative Examples 1 to 4>
Examples 2 and 3 and Comparative Examples 1 to 1 are the same as in Example 1 except that the chemical absorbers and / or hydrophobic physical adsorbents shown in Table 1 are used at the contents shown in Table 1. 4 films were obtained. As other hydrophobic physical adsorbents, mesoporous silica (Sigma-Aldrich Japan LLC) and activated carbon (FP-3, Osaka Gas Chemical Co., Ltd.) were used.

<Comparative Example 5>
A film of Comparative Example 5 which was a polyethylene film having a film thickness of 100 μm was obtained in the same manner as in Example 1 except that the chemical absorbent and the hydrophobic physical adsorbent were not contained.

<< Evaluation of moisture absorption >>
The prepared films of Examples 1 to 3 and Comparative Examples 1 to 5 were cut into 5 × 5 cm squares, and the mass of the films was measured. These films were then stored in a constant temperature and humidity chamber at 40 ° C. and 90% RH for 7 days, and the mass of the films after storage was measured. The amount of moisture absorbed was calculated from the change in mass before and after storage.

<< Evaluation of gas absorption >>
The prepared films of Examples 1 to 3 and Comparative Examples 1 to 5 were cut into 5 × 5 cm squares, and the mass of the films was measured. Then, the cut-out film and a glass bottle filled with 2 mL of isobutylamine were placed in a 140 mL glass bottle and stored in a sealed manner for 7 days, and the mass of the film after storage was measured. The amount of gas absorbed was calculated from the change in mass before and after storage.

The results are shown in Table 1. Here, the "theoretical value" of the moisture absorption amount of Example 1 referred to in Table 1 is calculated as follows using the moisture absorption amounts of Comparative Examples 1 and 2. The other "theoretical values" mentioned in Table 1 are also calculated in the same manner.
(Theoretical value) =
Moisture absorption amount of Comparative Example 1 (g / m ² ) × Content of chemical absorbent of Example 1 (mass%)
/ Content of chemical absorbent of Comparative Example 1 (mass%)
+ Moisture absorption amount of Comparative Example 2 (g / m ² ) × Content of hydrophobic physical adsorbent of Example 1 (mass%)
/ Content rate (mass%) of hydrophobic physical adsorbent of Comparative Example 2

From Table 1, the moisture absorbing and gas adsorbing films of Examples 1 to 4 containing the chemical absorbent and the hydrophobic physical adsorbent having an equilibrium humidity of 35% RH or more are the chemical absorbent or the hydrophobic physical adsorbent. It can be understood that the film has the same moisture absorption capacity and improved gas adsorption capacity as compared with the film of the comparative example containing the above alone.

10 Film for moisture absorption and gas adsorption 20 Base material layer 30 Reinforcing layer 100 Packaging laminate 200 Blister pack laminate

Claims (12)

It has a thermoplastic resin and an absorption layer containing a chemical absorbent and a hydrophobic physical adsorbent dispersed in the thermoplastic resin .
The total content of the chemical absorbent and the hydrophobic physical adsorbent in the absorbent layer is 5% by mass or more.
The equilibrium moisture hydrophobic physical adsorbent state, and are more RH 35%, and
A skin layer is further provided on one or both surfaces of the absorption layer.
Film for moisture absorption and gas adsorption. The film for moisture absorption and gas adsorption according to claim 1, wherein the equilibrium humidity of the chemical absorbent is 35% RH or less. The film for moisture absorption and gas adsorption according to claim 1 or 2, wherein the total content of the chemical absorbent and the hydrophobic physical adsorbent is 70% by mass or less. The moisture absorption and gas adsorption according to any one of claims 1 to 3 , wherein the chemical absorbent is selected from the group consisting of calcium oxide, calcium chloride, calcium sulfate, magnesium sulfate, sodium sulfate and a mixture thereof. the film. The film for moisture absorption and gas adsorption according to any one of claims 1 to 4 , wherein the physical adsorbent is selected from the group consisting of hydrophobic zeolite, activated carbon, mesoporous substances and mixtures thereof. A packaging laminate comprising the moisture absorbing and gas adsorbing film according to any one of claims 1 to 5 and a base material layer. The packaging laminate according to claim 6 , wherein the base material layer includes a barrier layer and a resin layer. The packaging laminate according to claim 6 or 7 is provided, and a part of the moisture absorbing and gas adsorbing film side of the packaging laminate of one or a plurality of sheets is this laminate. Bagged by being heat-sealed with other parts of the body or other film,
Packaging bag. A packaging bag containing the contents and the packaging bag according to claim 8, which contains the contents and the contents. The packaging laminate according to claim 6 or 7 , which is a blister pack laminate. A blister pack comprising the packaging laminate according to claim 10 , which has a pocket portion for storing the contents, and a lid material. A blister pack containing the contents, which comprises the blister pack according to claim 11, which contains the contents and the contents.

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