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JP5548129B2 - 不斉有機触媒 - Google Patents

不斉有機触媒 Download PDF

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Publication number
JP5548129B2
JP5548129B2 JP2010525576A JP2010525576A JP5548129B2 JP 5548129 B2 JP5548129 B2 JP 5548129B2 JP 2010525576 A JP2010525576 A JP 2010525576A JP 2010525576 A JP2010525576 A JP 2010525576A JP 5548129 B2 JP5548129 B2 JP 5548129B2
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JP
Japan
Prior art keywords
group
formula
asymmetric
added
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2010525576A
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English (en)
Japanese (ja)
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JPWO2010021093A1 (ja
Inventor
敬司 中山
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
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Daiichi Sankyo Co Ltd
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Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Priority to JP2010525576A priority Critical patent/JP5548129B2/ja
Publication of JPWO2010021093A1 publication Critical patent/JPWO2010021093A1/ja
Application granted granted Critical
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/09Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by at least two halogen atoms
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/04Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides containing carboxylic acids or their salts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00Asymmetric syntheses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/56Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/30Addition reactions at carbon centres, i.e. to either C-C or C-X multiple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2010525576A 2008-08-18 2009-08-04 不斉有機触媒 Expired - Fee Related JP5548129B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2010525576A JP5548129B2 (ja) 2008-08-18 2009-08-04 不斉有機触媒

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2008209411 2008-08-18
JP2008209411 2008-08-18
JP2010525576A JP5548129B2 (ja) 2008-08-18 2009-08-04 不斉有機触媒
PCT/JP2009/003699 WO2010021093A1 (fr) 2008-08-18 2009-08-04 Catalyseur organique asymétrique

Publications (2)

Publication Number Publication Date
JPWO2010021093A1 JPWO2010021093A1 (ja) 2012-01-26
JP5548129B2 true JP5548129B2 (ja) 2014-07-16

Family

ID=41706986

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010525576A Expired - Fee Related JP5548129B2 (ja) 2008-08-18 2009-08-04 不斉有機触媒

Country Status (2)

Country Link
JP (1) JP5548129B2 (fr)
WO (1) WO2010021093A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2793413C (fr) 2010-03-19 2015-11-24 Daiichi Sankyo Company, Limited Forme cristalline d'edoxaban tosylate monohydrate et son procede de fabrication
JP5780657B2 (ja) * 2010-07-02 2015-09-16 第一三共株式会社 光学活性ジアミン誘導体の塩の製造方法
BR112015011574A2 (pt) * 2012-11-23 2017-07-11 Daiichi Sankyo Co Ltd processo para produzir um composto
WO2014157612A1 (fr) * 2013-03-29 2014-10-02 第一三共株式会社 Procédé de production de (1s,4s,5s)-4-bromo-6- oxabicyclo[3.2.1]octane-7-one
CN105017121B (zh) * 2015-06-09 2017-11-21 哈尔滨工程大学 带有Fmoc‑L‑羟脯氨酸的光学活性苯乙炔衍生物及制备和应用方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002275118A (ja) * 2001-03-15 2002-09-25 Central Glass Co Ltd アルドール反応生成物の製造方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002275118A (ja) * 2001-03-15 2002-09-25 Central Glass Co Ltd アルドール反応生成物の製造方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6014018257; LUO Sanzhong et al.: 'Highly Enantioselective Direct syn- and anti-Aldol Reacitons of Dihydroxyacetones Catalyzed by Chira' Org. Lett. Vol.10,No.4, 20080221, page.653-656 *
JPN6014018258; GUIZZETTI Stefania et al.: 'Enantioselective Direct Aldol Reaction "on Water" Promoted by Chiral Organic Catalysts' Org. Lett. Vol.9,No.7, 20070329, page.1247-1250 *
JPN6014018262; NAKADAI Masakazu et al.: 'Diversity-based strategy for discovery of environmentally benign organocatalyst:diamine-protonic aci' Tetrahedron Vol.58,No.41, 20021007, page.8167-8177 *
JPN6014018264; NAKAYAMA Keiji et al.: 'Complete Switch of Product Selectivity in Asymmetric Direct Aldol Reaction with Two Different Chiral' J.Am.Chem.Coc Vol.130,No.52, 20081231, page.17666-17667 *

Also Published As

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JPWO2010021093A1 (ja) 2012-01-26
WO2010021093A1 (fr) 2010-02-25

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