JP3018155B2 - Detergent composition - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a detergent composition, and more particularly to a detergent composition which is excellent in detergency and foaming properties and has a high bactericidal effect. The present invention relates to a cleaning composition having excellent effects.

[0002]

2. Description of the Related Art Conventional detergent compositions often contain an anionic surfactant for the purpose of obtaining excellent detergency and foaming power.

[0003] On the other hand, a cleaning agent, especially a cleaning agent for hair and body, is required to have a bactericidal effect in addition to a cleaning effect, and many studies have been made on a cleaning agent having a germicidal effect. Detergent compositions using a bactericide are known.

[0004] However, when an anionic surfactant and a cationic germicide are used in combination, these complexes are formed, resulting in a problem that not only the detergency is reduced but also the bactericidal effect is not sufficiently exhibited.

[0005]

SUMMARY OF THE INVENTION Accordingly, an object of the present invention is to provide a cleaning agent which is excellent in detergency and foaming properties, and is also excellent in disinfecting properties, so that dandruff, kayumi on the scalp, kayumi on the body and odor can be effectively prevented. Agent composition.

[0006]

Means for Solving the Problems In view of such circumstances, the present inventors have conducted intensive studies and as a result, have found that anionic surfactants are
It has been found that the combination of a specific cationic bactericide and a specific antibacterial agent in a specific weight ratio improves the bactericidal effect of the cation in the anion and the effect of the antibacterial agent synergistically. The present invention, which is a cleaning composition having excellent effects such as dandruff, anti-kayumi, and deodorization, has been completed.

That is, the present invention provides the following component (A):
(B) and (C): (A) 5 to 50% by weight of an anionic surfactant excluding higher fatty acid salt; (B) one of the cationic germicides represented by the following general formulas (1) to (4) Or two or more 0.2 to 5% by weight;

[0008]

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[R ¹ and R ² each represent a long-chain alkyl group, a long-chain alkenyl group or a long-chain hydroxyalkyl group having 6 to 14 carbon atoms and a total of 16 to 26 carbon atoms. May be. R ³ and R ⁴ have 1 carbon atom
Represents an alkyl group, a hydroxyalkyl group or a polyoxyethylene group having an average number of moles of 10 or less, which may be the same or different. Z ¹ is a halogen atom, an amino acid, a fatty acid, an anionic residue of a phosphate ester, a phosphonate ester, a sulfonate ester or a sulfate ester having a linear or branched alkyl or alkenyl group having 1 to 30 carbon atoms, or polymerization Degree 3
An anionic oligomer or polymer containing a formalin condensate of a sulfonated polycyclic aromatic compound having styrene sulfonic acid or having a hydrocarbon group as a substituent is described. ]

[0010]

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Wherein R ⁵ is a hydrocarbon group having 8 to 14 carbon atoms or

[0012]

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Wherein Z ¹ is a halogen atom, an amino acid, a fatty acid, a phosphoric ester, a phosphonic ester or a sulfonic ester having a linear or branched alkyl or alkenyl group having 1 to 30 carbon atoms. Or an anionic residue containing an anionic residue of a sulfate ester or a formalin condensate of a sulfonated polycyclic aromatic compound having styrenesulfonic acid having a degree of polymerization of 3 or more or having a hydrocarbon group as a substituent Shows oligomer or polymer. ]

[0014]

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[Z ² represents gluconic acid, acetic acid or hydrochloric acid. ]

[0016]

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[Wherein, R ⁶ represents a straight-chain or branched-chain alkyl group having 6 to 18 carbon atoms, and Z ³ represents a halogen atom, an amino acid, a fatty acid, a straight-chain or branched-chain alkyl group having 1 to 30 carbon atoms. May have an anionic residue of a phosphoric acid ester, a phosphonic acid ester, a sulfonic acid ester or a sulfuric acid ester having a carboxylic acid group or an alkenyl group, or a styrenesulfonic acid having a degree of polymerization of 3 or more, or may have a hydrocarbon group as a substituent. An anionic oligomer or polymer containing a formalin condensate of a sulfonated cyclic aromatic compound is shown. (C) triclosan, triclocarban, DMDM hydantoin, pyroctone auramine, zinc pyrithione,
It contains one or more antibacterial agents selected from the group consisting of selenium disulfide and 3-methyl-4- (1-methylethyl) phenol, and a cationic bactericide of component (B) and (C) It is intended to provide a detergent composition characterized in that the compounding weight ratio (B) / (C) of the component to the antibacterial agent is 0.1 to 25 and does not contain a clay mineral.

[0018]

BEST MODE FOR CARRYING OUT THE INVENTION The anionic surfactant used in the present invention is not particularly limited as long as it is other than a higher fatty acid salt. For example, polyoxyalkylene alkyl ether carboxylic acid or a salt thereof, alkyl sulfate, alkyl sulfonic acid Or a salt thereof, an alkylbenzenesulfonic acid or a salt thereof, a polyoxyalkylene alkyl ether sulfate, an alkyl phosphoric acid or a salt thereof, a polyoxyalkylene alkyl ether phosphoric acid or a salt thereof, a polyoxyalkylene alkylamide ether carboxylic acid or a salt thereof, an alkyl Sulfosuccinate, polyoxyalkylene alkyl ether sulfosuccinate, N-acyl-N-methyltaurate, N-acylsarcosine, α-olefinsulfonic acid or a salt thereof, acylated a Thionates, acylated glutamic acid or salts thereof, and the like, among which more preferred are alkyl sulfates, polyoxyalkylene alkyl ether sulfates, alkyl phosphates, polyoxyalkylene alkyl amide ether carboxylates, Acylated isethionate, polyoxyalkylene alkyl ether carboxylic acid, polyoxyalkylene alkyl ether sulfosuccinate, especially the following general formula

[0019]

[Image Omitted] R ⁷ O- (CH ₂ CH ₂ O) _n -SO ₃ M ¹

Wherein R ⁷ represents a linear or branched alkyl or alkenyl group having 8 to 20 carbon atoms, n represents an average of 0 to 10, M ¹ represents an alkali metal atom, an alkaline earth A metal-like atom, an ammonium salt, an alkylammonium group or an alkanolammonium group], or a polyoxyalkylene alkyl ether sulfate.

The amount of the component (A) is 5% in the detergent composition.
-50% by weight, especially 5-30% by weight, more preferably 7-7% by weight.
It is preferable to set it to 20% by weight.

The cationic bactericide of the component (B) used in the present invention includes a quaternary ammonium salt represented by the general formula (1), a benzalkonium salt and a benzethonium salt represented by the general formula (2). One or more selected from a chlorhexidine salt represented by the general formula (3) and a pyridinium salt represented by the general formula (4).

A halogen atom is particularly preferred as Z ¹ in the general formulas (1) and (2).

Specific examples of the component (B) include benzalkonium chloride, benzethonium chloride, cetylpyridinium chloride, chlorhexidine gluconate, chlorhexidine acetate, chlorhexidine hydrochloride and the like, and particularly those represented by the general formula (2): For example, benzalkonium chloride and benzethonium chloride are preferable, and further, the compound represented by the general formula (2a)

[0025]

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Wherein R ^5a represents a linear or branched alkyl or alkenyl group having 8 to 14 carbon atoms.

A benzalkonium-type fungicide represented by the formula:
For example, benzalkonium chloride is preferred.

The cationic bactericide of the component (B) may be used alone or in combination of two or more kinds. From the viewpoint of bactericidal effect and irritation, 0.2 to 5% by weight is blended in the whole composition. And more preferably 0.3 to 4% by weight, more preferably 0.4 to 3% by weight.

As the antibacterial agent of the component (C) used in the present invention, triclosan, triclocarban, pyrocton auramine, DMDM hydantoin, zinc pyrithione,
Selenium disulfide, 3-methyl-4- (1-methylethyl)
Phenols may be used alone or in combination of two or more. Among them, preferred are triclosan, triclocarban, DMDM hydantoin, zinc pyrithione, and pyrocton auramine.

The amount of component (C) is preferably determined by the ratio with component (B), and the weight ratio (B) / (C) of component (B) to component (C) is 0.1. It is preferable to set it in the range of 25 to 25, especially 0.1 to 20 in order to obtain a synergistic effect of antibacterial properties.

The detergent composition of the present invention may further contain a chelating agent to further enhance the sterilizing and antibacterial effects.

The metal chelating agent used in the present invention is not particularly limited as long as it has the ability to chelate a metal ion. Examples thereof include aminopolycarboxylic acid-based chelating agents, aromatic and aliphatic carboxylic acid-based chelating agents, Amino acid chelating agents, ether polycarboxylic acid chelating agents, iminodimethylphosphonic acid (IDP), alkyl diphosphonic acid (ADPA), 1-hydroxyethane-1,
Phosphonic acid chelating agents such as 1-diphosphonic acid (DEQUEST ^™ 2010), hydroxycarboxylic acid chelating agents, phosphoric acid chelating agents, polymer electrolyte (including oligomer electrolyte) chelating agents and dimethylglyoxime (DG) No. Each of these chelating agents may be in a free acid form or in a salt form such as a sodium salt, a potassium salt, and an ammonium salt. In addition, they may be in the form of their hydrolyzable ester derivatives.

Specific examples of the aminopolycarboxylic acid chelating agent include: a) a compound represented by the chemical formula R ⁸ (Y) ₂ , b) a compound represented by the chemical formula N (Y) ₃ , c) a chemical formula R ⁸ -N A compound represented by (Y) —CH ₂ CH ₂ —N (Y) —R ⁸ , d) a chemical formula: a compound represented by R ⁸ —N (Y) —CH ₂ CH ₂ —N (Y) ₂ , e) a chemical formula A compound represented by (Y) ₂ NR ⁹ -N (Y) ₂ , and f) a compound similar to the compound of e), wherein the compound contains 4 or more Y, for example, a compound represented by the formula

[0034]

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The compound represented by the following formula:

In the above formula, Y is -CH ₂ COOH or -CH ₂ CH ₂ COOH
R ⁸ represents a group constituting a known chelating agent such as a hydrogen atom, an alkyl group, a hydroxyl group, a hydroxyalkyl group, and R ⁹ represents a known chelating agent of this kind such as an alkylene group or a cycloalkylene group. A group to be used.

A typical example of an aminopolycarboxylic acid chelating agent is ethylenediaminetetraacetic acid (EDT).
A), cyclohexanediaminetetraacetic acid (CDT
A), nitrilotriacetic acid (NTA), iminodiacetic acid (I
DA), N- (2-hydroxyethyl) iminodiacetic acid (HIMDA), diethylenetriaminepentaacetic acid (D
TPA), N- (2-hydroxyethyl) ethylenediaminetriacetic acid (EDTA-OH) and glycol etherdiaminetetraacetic acid (GEDTA), and salts thereof.

Examples of the aromatic or aliphatic carboxylic acid chelating agents used in the present invention include oxalic acid, malonic acid, succinic acid, glutaric acid, adipic acid, itaconic acid, aconitic acid, pyruvic acid, salicylic acid, Examples include acetylsalicylic acid, hydroxybenzoic acid, aminobenzoic acid (including anthranilic acid), phthalic acid, trimellitic acid and gallic acid, and salts, methyl esters and ethyl esters thereof. Examples of the amino acid chelating agent used in the present invention include glycine, serine, alanine, lysine, cystine, cysteine, ethionine, tyrosine, methionine, and salts and derivatives thereof.

Further, examples of the ether polycarboxylic acid chelating agent used in the present invention include diglycolic acid, compounds represented by the following formula, analogous compounds thereof and salts thereof (for example, sodium salts).

[0040]

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Examples of the hydroxycarboxylic acid chelating agents used in the present invention include malic acid, citric acid, glycolic acid, gluconic acid, heptonic acid, tartaric acid, lactic acid and salts thereof. Examples of the phosphate chelating agent used in the present invention include orthophosphoric acid, pyrophosphoric acid, triphosphoric acid and polyphosphoric acid. Examples of the polymer electrolyte (including oligomer electrolyte) chelating agent used in the present invention include acrylic acid polymer, maleic anhydride polymer, α-hydroxyacrylic acid polymer, itaconic acid polymer, Copolymers composed of two or more kinds of constituent monomers of the union and epoxy succinic acid polymers are exemplified. Furthermore, in the present invention, ascorbic acid, thioglycolic acid, phytic acid, glyoxylic acid and glyoxalic acid, and salts thereof can also be suitably used as a chelating agent. Preferred chelating agents include
Ethylenediaminetetraacetic acid (EDTA), succinic acid,
Salicylic acid, oxalic acid, lactic acid, fumaric acid, tartaric acid, 1-
Hydroxyethane-1,1-diphosphonic acid and salts thereof. The metal chelating agent contained 0.1% in the total composition.
-10% by weight, preferably 0.2-5% by weight.

Further, an antibacterial agent other than the above antibacterial agent can be added to the composition of the present invention within a range not to impair the present invention. Examples of such antibacterial agents include those described in the science of preservatives and bactericides for cosmetics and pharmaceuticals (Fragrance Journal, edited by John J. Kabbalah).

Further, an anti-inflammatory agent may be added within a range not to impair the present invention. Such anti-inflammatory agents include glycyrrhizic acid, dihydrocholesterine, allantoin and the like. The detergent composition of the present invention further includes a commonly used amphoteric surfactant such as carbobetaine, sulfobetaine, or hydroxysulfobetaine, or an amine oxide surfactant, an alkanolamide surfactant, or an amide amino acid surfactant. An activator or the like can be added within a range that does not impair the effects of the present invention.

Further, the detergent composition of the present invention contains 0.1 to 5% by weight of a silicone derivative,
A good sliding feeling and a smooth feeling can be obtained. The silicone derivative is not particularly limited as long as it is generally used in detergents and cosmetics. Examples thereof include dimethylpolysiloxane, methylphenylpolysiloxane, polyether-modified silicone, epoxy-modified silicone, alkoxy-modified silicone, and amino-modified silicone. , Fatty acid-modified silicone, fluorine-modified silicone and the like.

A conditioning shampoo can be prepared by adding a conditioning agent to the detergent composition of the present invention in an amount of about 0.1 to 5% by weight. Examples of the conditioning agent include cationic cellulose derivatives, cationic starch, cationic guar gum derivatives, copolymers of diallyl quaternary ammonium salts and acrylamide, quaternized polyvinylpyrrolidone derivatives, and polyglycolamine condensates. Preferably, a polymer is used.

Further, in addition to the above components, the detergent composition of the present invention may further contain, if necessary, components usually incorporated in cosmetics, pharmaceuticals, foods, etc., for example, propylene glycol, glycerin, diethylene glycol monoethyl ether. ,
Moisturizing agents such as sorbitol and panthenol; coloring agents such as dyes and pigments; pearling agents, chitosan derivatives such as hydroxypropyl chitosan; various compounding fragrances; (MICELLE PRES
S 1985)] can be appropriately compounded as long as the effects of the present invention are not impaired.

The detergent composition of the present invention can be produced according to a usual method, and can be in the form of paste, gel, liquid or the like. It is also suitable as a hair and body cleanser.

[0048]

The cleaning composition of the present invention has excellent detergency and foaming properties, and has a higher bactericidal effect and a broader germicidal spectrum when used in combination with an antibacterial agent and a bactericide. Sufficient anti-dandruff property, antipruritic property and deodorant effect on body and scalp.

[0049]

EXAMPLES Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples. In addition, the compounding amount of each component in the following examples was shown on the basis of the effective component. “%” Indicates “% by weight”.

Example 1 A cleaning agent having the following composition was prepared and subjected to a sterilization test.

[0051]

[Table 1] Triethanolamine monolauryl phosphate 10% ^* Benzalkonium chloride 0, 0.2, 0.6, 0.8, 0.9, 0.95, 1.0% Triclocarban 0, 0.05, 0.1, 0.2, 0.4, 0.8, 1.0% Water balance ^* C ₁₂ / C ₁₄ = 50/50 (weight ratio), same hereafter

In the above composition, the total amount of benzalkonium chloride and triclocarban was blended so as to be 1.0% by weight, and the bactericidal effect on Escherichia coli at that time is shown in Table 2. (Disinfection test method) Test bacteria (Escherichia coli IFO 397
For 2), a culture solution pre-cultured in an SCD medium (manufactured by Nippon Pharmaceutical Co., Ltd.) was used. 0.1 ml of culture solution (10 ⁹ -10
¹⁰ cells / ml) in sterile water at a predetermined concentration (composition dilution × 1, × 2, × 4, × 8, × 16, × 32, × 64, ×
128, × 256, × 512) were inoculated into 10 ml of each detergent composition. After a certain time (2.5,
Every 5, 10, 15 minutes), one loopful of loop was taken, inoculated into a growth medium, cultured at 30 ° C. for 3 days, and the presence or absence of bacterial growth was determined. In the sterilization test method, when growth was not observed at all dilution concentrations and all reaction times, the number of sterilization areas was expressed as 40.

[0053]

[Table 2]

From Table 2, when the total blending weight of benzalkonium chloride and triclocarban was set to 1.0%, a clear synergistic effect was observed when used in combination as compared with the bactericidal effect of each of them alone. .

Example 2 Evaluation of the bactericidal effect was carried out in accordance with the bactericidal test method of Example 1 using the detergents having the composition shown in Table 3. However, test bacteria, Escherichia coli IFO 3972, Staphylococcus au
For reus IFO 12732, use SCD medium
For alassezia furfur IFO 0656, Malt-YE-Tween
A culture solution pre-cultured in 80 medium was used. The growth medium was grown on SCD medium for E. coli. St. aureus and grown on Malt-YE-Tween 80 medium for M. furfur. Further, the deodorant effect and the antidandruff effect were evaluated by the following methods and criteria. Table 3 with the results
And Table 4 below.

(Evaluation Method and Evaluation Criteria for Antidandruff Property) For each cleaning composition, five panelists of each male and female
The anti-dandruff effect when the hair was washed once a day for 4 weeks was evaluated according to the following criteria.

(Evaluation Criteria) 5: Feel the dandruff decreased 4: Felt the dandruff slightly reduced 3: Felt no change from now on 2: Felt the dandruff slightly increased 1: Dandruff Felt increased

The results were expressed as an anti-dandruff effect by the average value of 10 panelists according to the following criteria.

◎: 4.3 or more good ○: 3.6 to 4.2 slightly good Δ: 2.5 to 3.5 normal ×: 2.4 or less bad

(Evaluation Method and Evaluation Criteria for Deodorant Effect)

For each cleaning composition, a use test was conducted once a day for two weeks by five panelists of each gender. The deodorant effect is evaluated by a professional evaluator after final cleaning.
The body odor after the passage of time was evaluated according to the following criteria.

(Evaluation criteria) 5: No smell 4: Slight smell 3: Smell 2: Very smell 1: Very strong smell

The results were expressed as an average of 10 panelists as a deodorant effect according to the following criteria. ◎: Good for 4.0 or more ○: Somewhat good for 3.2 to 3.9 △: Normal for 2.5 to 3.1 ×: Poor for 2.4 or less

[0064]

[Table 3]

[0065]

[Table 4]

As shown in Tables 3 and 4, when the cationic bactericide (B) and the antibacterial agent (C) of the present invention are used in combination, good bactericidal, antidandruff and deodorant effects are obtained due to their synergistic effects. Admitted.

Example 3 (Anti-dandruff shampoo) An anti-dandruff shampoo having the following composition was produced by a conventional method.

TABLE 5 Sodium polyoxyethylene (2) lauryl ether sulfate 10% Lauroyl diethanolamide 1% Amidopropyl betaine laurate 3% Benzalkonium chloride 0.5% Piroctone auramine 0.2% Disodium succinate 0. 5% Spice 0.5% Purified water Balance

The obtained anti-dandruff shampoo was excellent in washing performance and foaming property, and had a high anti-dandruff effect.

Example 4 (Body shampoo) A body shampoo having the following composition was produced by a conventional method.

TABLE 6 Sodium monolauryl phosphate 10% Lauroyl diethanolamide 1% Amidopropyl betaine laurate 2% Cetylpyridinium chloride 0.5% 3-Methyl-4- (1-methylethyl) phenol 0.1% Ethylenediaminetetraacetic acid Disodium 0.5% Perfume 0.5% Purified water Balance

The obtained body shampoo was excellent in washing performance and foaming property, and had a high deodorizing effect.

Example 5 (Body Shampoo) A body shampoo having the following composition was produced by a conventional method.

Table 7 Polyoxyethylene (3) sodium lauric amide ether acetate 10% Polyoxyethylene (10) sodium lauryl ether acetate 5% Benzalkonium chloride 0.5% Triclosan 0.3% Ethylenediamine tetraacetate 0. 5% Fragrance 0.3% Purified water Balance

The obtained body shampoo was excellent in washing performance and foaming property, and had a high deodorizing effect.

Example 6 (Anti-dandruff shampoo) An anti-dandruff shampoo having the following composition was produced by a conventional method.

Table 8 Polyoxyethylene (2) lauryl ether disodium sulfosuccinate 12% lauroyldiethanolamide 2% laurylhydroxysulfobetaine 1% benzalkonium chloride 0.5% zinc pyrithione 0.2% disodium succinate 0.4% Perfume 0.5% Purified water Balance

The obtained anti-dandruff shampoo was excellent in washing performance and foaming property, and had a high anti-dandruff effect.

Continuation of the front page (51) Int.Cl. ⁷ Identification symbol FI C11D 3/36 C11D 3/36 (72) Inventor Yasuhiro Doi 1334 Minato, Wakayama-shi, Wakayama Kao Corporation Laboratory (56) References JP 63 −139998 (JP, A) (58) Fields investigated (Int. Cl. ⁷ , DB name) C11D 3/20 A61K 7/50 C11D 3/24 C11D 3/26 C11D 3/34 C11D 3/36

Claims (2)

(57) [Claims] 1. The following components (A), (B) and (C): (A) 5 to 50% by weight of an anionic surfactant excluding higher fatty acid salt; (B) the following general formulas (1) to (1): One or more of the cationic germicides represented by 4) 0.2 to 5% by weight; [R ¹ and R ² each have 6 to 14 carbon atoms and a total of 16 to
26 represents a long-chain alkyl group, a long-chain alkenyl group, or a long-chain hydroxyalkyl group, which may be the same or different. R ³ and R ^{4 each} represent an alkyl group having 1 to 3 carbon atoms, a hydroxyalkyl group or a polyoxyethylene group having an average number of moles of 10 or less, which may be the same or different. Z ¹ is a halogen atom, an amino acid, a fatty acid, an anionic residue of a phosphate ester, a phosphonate ester, a sulfonate ester or a sulfate ester having a linear or branched alkyl or alkenyl group having 1 to 30 carbon atoms, or polymerization An anionic oligomer or polymer containing a formalin condensate of a sulfonated polycyclic aromatic compound having styrene sulfonic acid having a degree of 3 or more or having a hydrocarbon group as a substituent is shown. [Chemical formula 2] [Wherein, R ⁵ represents a hydrocarbon group having 8 to 14 carbon atoms or Wherein Z ¹ represents a halogen atom, an amino acid, a fatty acid, a phosphoric ester, a phosphonate, a sulfonate or a sulfate having a linear or branched alkyl or alkenyl group having 1 to 30 carbon atoms. Oligomer or polymer containing a formalin condensate of a sulfonated polycyclic aromatic compound having styrenesulfonic acid having a polymerization degree of 3 or more or having a hydrocarbon group as a substituent Is shown. [Formula 4] [Z ² represents gluconic acid, acetic acid or hydrochloric acid. [Chemical formula 5] [Wherein, R ⁶ represents a linear or branched alkyl group having 6 to 18 carbon atoms, and Z ³ represents a halogen atom, an amino acid, a fatty acid, a linear or branched alkyl group or alkenyl having 1 to 30 carbon atoms. Anionic residue of a phosphoric acid ester, a phosphonic acid ester, a sulfonic acid ester or a sulfuric acid ester, or a polycyclic aromatic compound having styrenesulfonic acid having a degree of polymerization of 3 or more or having a hydrocarbon group as a substituent An anionic oligomer or polymer containing a formalin condensate of a sulfonated group compound is shown. (C) triclosan, triclocarban, DMDM hydantoin, pyroctone auramine, zinc pyrithione,
One or more antibacterial agents selected from the group consisting of selenium disulfide and 3-methyl-4- (1-methylethyl) phenol; and (C) a cationic disinfectant and (C) Component polymerization ratio (B) / (C) with antimicrobial agent of component is 0.1 to 25
And a detergent composition containing no clay mineral. 2. The cleaning composition according to claim 1, further comprising a metal chelating agent.