JP3059795B2 - Mental stability food - Google Patents
Mental stability foodInfo
- Publication number
- JP3059795B2 JP3059795B2 JP3242503A JP24250391A JP3059795B2 JP 3059795 B2 JP3059795 B2 JP 3059795B2 JP 3242503 A JP3242503 A JP 3242503A JP 24250391 A JP24250391 A JP 24250391A JP 3059795 B2 JP3059795 B2 JP 3059795B2
- Authority
- JP
- Japan
- Prior art keywords
- production method
- food
- extract
- test
- reference example
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 235000013305 food Nutrition 0.000 title claims description 18
- 230000003340 mental effect Effects 0.000 title description 2
- 230000002936 tranquilizing effect Effects 0.000 claims description 13
- 239000000284 extract Substances 0.000 claims description 10
- 239000003204 tranquilizing agent Substances 0.000 claims description 8
- 229940125725 tranquilizer Drugs 0.000 claims description 6
- 240000001972 Gardenia jasminoides Species 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 description 18
- 241000157835 Gardenia Species 0.000 description 8
- 239000003814 drug Substances 0.000 description 8
- 229940079593 drug Drugs 0.000 description 8
- 239000000796 flavoring agent Substances 0.000 description 8
- 235000019634 flavors Nutrition 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 235000004347 Perilla Nutrition 0.000 description 6
- 241000229722 Perilla <angiosperm> Species 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 230000006742 locomotor activity Effects 0.000 description 6
- 208000019914 Mental Fatigue Diseases 0.000 description 5
- 230000001953 sensory effect Effects 0.000 description 5
- 241000699670 Mus sp. Species 0.000 description 4
- 230000037396 body weight Effects 0.000 description 4
- 235000009508 confectionery Nutrition 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000000419 plant extract Substances 0.000 description 4
- 230000001629 suppression Effects 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 241000699666 Mus <mouse, genus> Species 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 239000006188 syrup Substances 0.000 description 3
- 235000020357 syrup Nutrition 0.000 description 3
- 235000019640 taste Nutrition 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- MIDXCONKKJTLDX-UHFFFAOYSA-N 3,5-dimethylcyclopentane-1,2-dione Chemical compound CC1CC(C)C(=O)C1=O MIDXCONKKJTLDX-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 235000019502 Orange oil Nutrition 0.000 description 2
- 239000002249 anxiolytic agent Substances 0.000 description 2
- 230000000949 anxiolytic effect Effects 0.000 description 2
- 229940005530 anxiolytics Drugs 0.000 description 2
- 235000013736 caramel Nutrition 0.000 description 2
- 230000001055 chewing effect Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 229940083980 lavender extract Drugs 0.000 description 2
- 235000020723 lavender extract Nutrition 0.000 description 2
- 230000003137 locomotive effect Effects 0.000 description 2
- 239000010502 orange oil Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102220547770 Inducible T-cell costimulator_A23L_mutation Human genes 0.000 description 1
- 206010029333 Neurosis Diseases 0.000 description 1
- 238000000692 Student's t-test Methods 0.000 description 1
- 244000126014 Valeriana officinalis Species 0.000 description 1
- 235000013832 Valeriana officinalis Nutrition 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000003125 aqueous solvent Substances 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 244000309464 bull Species 0.000 description 1
- 235000014121 butter Nutrition 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 235000020186 condensed milk Nutrition 0.000 description 1
- 235000011850 desserts Nutrition 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 235000021552 granulated sugar Nutrition 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 208000015238 neurotic disease Diseases 0.000 description 1
- 235000019645 odor Nutrition 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102220240796 rs553605556 Human genes 0.000 description 1
- 201000000980 schizophrenia Diseases 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000012353 t test Methods 0.000 description 1
- 235000016788 valerian Nutrition 0.000 description 1
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Description
【0001】[0001]
【産業上の利用分野】本発明は、クチナシのエキスを含
有することを特徴とし、ストレス緩和作用を有し、良好
な風味を保持した精神安定用食品に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a tranquilizer which contains a gardenia extract, has a stress relieving action, and retains a good flavor.
【0002】[0002]
【従来の技術】現代人は,ストレスという言葉に代表さ
れる精神的疲労を感じていることが指摘されている。こ
のうち,神経症,うつ病,精神分裂病等の強度の精神的
疲労の治療に関しては,精神安定薬および抗不安薬等の
合成医薬品の投与が行われ,効果が認められている。し
かし,これら合成医薬品の多くは副作用を伴うので,病
的でないストレス等の軽度の精神的疲労を感じる人に対
しては投与されない。また,天然物由来原料を用いた生
薬にも精神安定薬や抗不安薬と類似の作用を持つものが
見出されている。しかし,生薬は緩和な作用を期待でき
る反面比較的大量に服用する必要があり,特有の臭い,
苦味を伴うものの場合には服用しづらいという欠点があ
った。このように従来の合成医薬品や生薬は, 副作用が
あったり,服用しづらい等の欠点があり, ストレスなど
の軽度の精神的疲労に対する有効な治療法は見出されて
いないのが現状である。2. Description of the Related Art It has been pointed out that modern people feel mental fatigue represented by the word stress. Among them, administration of synthetic drugs such as tranquilizers and anxiolytics is effective in treating severe mental fatigue such as neurosis, depression, and schizophrenia, and the effect has been recognized. However, many of these synthetic drugs have side effects and are not administered to people who experience mild mental fatigue such as non-pathological stress. In addition, some crude drugs using raw materials derived from natural products have effects similar to those of tranquilizers and anxiolytics. However, although crude drugs can be expected to have a mild effect, they need to be taken in relatively large amounts,
In the case of those with bitterness, there was a drawback that it was difficult to take. As described above, conventional synthetic drugs and crude drugs have disadvantages such as side effects and difficulty in taking them, and at present, there is no effective treatment method for mild mental fatigue such as stress.
【0003】こうした観点から,特開平1-242533号公報
に, 植物エキスを含有すると共に良好な呈味性を保持す
る精神安定用飲食物が開示されている。しかし, ここに
開示されている飲食物に含有せしめるラベンダーエキス
は特有の香粧品様の香りのため嗜好が一般的でない。ま
た,ラベンダーエキスを単独でガムベースに含有せしめ
た場合には,精神安定効果の指標として用いている皮膚
電気反応は抑制の傾向を示すものの有意差を認めるまで
は抑制しておらず,カノコソウなど臭気を伴う生薬との
併用によりはじめて有意な抑制が示されている。[0003] From such a viewpoint, Japanese Patent Application Laid-Open No. 1-242533 discloses a food and drink for mental stability that contains a plant extract and maintains good taste. However, the taste of the lavender extract to be contained in foods and drinks disclosed herein is not common because of the unique cosmetic-like aroma. In addition, when lavender extract alone was included in the gum base, the electrodermal response used as an indicator of the tranquilizing effect showed a tendency of suppression but was not suppressed until a significant difference was observed, and odors such as valerian Significant suppression has been shown only with concomitant use with crude drugs.
【0004】[0004]
【発明が解決しようとする課題】すなわち,本発明の目
的とするところは、ストレス緩和に有効であり,良好な
風味を保持した精神安定用食品を提供するにある。That is, an object of the present invention is to provide a tranquilizer food which is effective in relieving stress and has good flavor.
【0005】[0005]
【課題を解決するための手段】本発明は、クチナシのエ
キスを配合することを特徴とする精神安定用食品であ
る。SUMMARY OF THE INVENTION The present invention is a tranquilizer food characterized by incorporating a gardenia extract.
【0006】本発明の精神安定用食品に含有せしめるエ
キスは、クチナシの実等から公知の方法によって抽出さ
れ、例えば、各植物の原体に水,エタノール,メタノー
ルなどの水性溶媒,望ましくは水を10〜20倍量加え90〜
100℃の温度下で0.5〜2時間抽出し、固体を除いた後減
圧下に1/10〜1/30に濃縮あるいは乾燥する方法等があ
る。The extract to be contained in the tranquilizer food of the present invention is extracted from gardenia seeds and the like by a known method. For example, an aqueous solvent such as water, ethanol, methanol, or the like, preferably water is added to the raw material of each plant. 10 to 20 times the amount added 90 to
There is a method of extracting at a temperature of 100 ° C. for 0.5 to 2 hours, removing solids, and then concentrating or drying under reduced pressure to 1/10 to 1/30.
【0007】クチナシエキスの含量は、食品中0.1〜10
重量%の範囲が、風味及び精神安定効果の点で好まし
い。The content of the gardenia extract is 0.1 to 10% in the food.
The range of% by weight is preferable in view of flavor and tranquilizing effect.
【0008】これらの植物性エキスを含有せしめる食品
として, 飲料,焼菓子, チョコレート, 冷菓等各種食品
を挙げることができるが, 特に,キャンデー,ガム並び
にキャラメルの咀嚼様食品が適している。例えば, 食品
が,キャンデーであれば舐める行為による精神安定効果
との,ガムであれば噛む行為による精神安定効果との,
またキャラメルであれば舐める行為と噛む行為両者との
相乗効果が期待できるので,ストレス緩和により効果的
でかつ添加量が少量ですむため風味の良好な精神安定用
食品の提供が可能となる。以下,実施例によって,本発
明を更に詳細に説明する。As foods containing these plant extracts, various foods such as beverages, baked confectionery, chocolate, and frozen desserts can be mentioned, and candy, gum and caramel chew-like foods are particularly suitable. For example, if the food is candy, the tranquilizing effect of licking, and if the food is gum, the tranquilizing effect of chewing,
In addition, since the synergistic effect of both licking and chewing can be expected with caramel, it is possible to provide a tranquilizing food with good flavor because it is effective by reducing stress and requires a small amount of addition. Hereinafter, the present invention will be described in more detail with reference to examples.
【0009】[0009]
【実施例】実施例に先立って,植物エキスの選択に用い
たマウス自発運動抑制試験および本発明の評価に用いた
専門パネル20名による官能試験の方法について記載す
る。EXAMPLES Prior to the examples, methods for a mouse locomotor inhibition test used for selecting a plant extract and a sensory test method by 20 specialized panels used for evaluation of the present invention will be described.
【0010】[0010]
【マウス自発運動抑制試験方法】検体をそれぞれ蒸留水
に溶解し,この溶液を20ml/kg 体重の割合で ddY雄性マ
ウス( 5週齢, 1群10匹)に経口投与した(検体の投与
量はそれぞれ3g/kg体重または9g/kg体重)。対照群マ
ウスには水のみを20ml/kg体重の割合で経口投与した。[Mouse locomotor inhibition test method] Each sample was dissolved in distilled water, and this solution was orally administered to ddY male mice (5 weeks old, 10 mice per group) at a rate of 20 ml / kg body weight. 3 g / kg body weight or 9 g / kg body weight, respectively). Control group mice were orally administered water alone at a rate of 20 ml / kg body weight.
【0011】次に, 実験動物運動量測定装置ACTY-303
(バイオメディカ社製)でマウスの自発運動量を測定し
た。検体投与後1時間に於ける各群の自発運動量の平均
値および標準誤差を算出すると共に,検体投与群の自発
運動量と対照群の自発運動量との間の有意差検定を行っ
た。Next, an experimental animal locomotion measuring device ACTY-303
(Biomedica) was used to measure the locomotor activity of the mice. One hour after the sample administration, the average value and standard error of the locomotor activity of each group were calculated, and a significant difference test between the locomotor activity of the sample administration group and the spontaneous locomotor activity of the control group was performed.
【0012】[0012]
【官能試験方法】植物性成分を含有せしめた精神安定用
食品のストレス緩和効果および風味を評価するために成
人男女各10人合計20人を被験者として官能検査を行っ
た。被験者に, 喫食10分後, 気分のおちつき具合と風
味に関して次の表1に示す検査項目について官能検査を
行った。[Sensory test method] In order to evaluate the stress relieving effect and flavor of the tranquilizer food containing plant ingredients, a sensory test was conducted on a total of 20 subjects each of 10 male and female adults. Ten minutes after eating, the test subjects were subjected to a sensory test for the test items shown in Table 1 below for the feeling of rest and the flavor.
【0013】[0013]
【表1】 [Table 1]
【0014】[0014]
【シソ葉エキスの製法】シソの葉 100gを 1.8 lの水で
1時間 100℃で抽出した後,濾過してろ液を65gにまで
減圧濃縮して得た。[Preparation of perilla leaf extract] 100 g of perilla leaves were extracted with 1.8 l of water for 1 hour at 100 ° C., filtered, and the filtrate was concentrated under reduced pressure to 65 g.
【0015】[0015]
【クチナシエキスの製法】クチナシの実 100gを 1.6 l
の水で1時間 100℃で抽出した後,濾過してろ液を 120
gにまで減圧濃縮して得た。[Production method of gardenia extract] 1.6 g of gardenia fruit 100g
After extracting with water at 100 ° C for 1 hour, filter and filter
g.
【0016】[0016]
【表2】 [Table 2]
【0017】[0017]
【製法】グラニュー糖,水飴,水を155℃で煮詰め,
80℃迄冷却した後,シソ葉エキス,クエン酸,オレン
ジオイルを添加混合後,15×25×8mmに成型した。[Production method] Granulated sugar, starch syrup, and water are boiled down at 155 ° C.
After cooling to 80 ° C., perilla leaf extract, citric acid and orange oil were added and mixed, and then molded into a size of 15 × 25 × 8 mm.
【0018】[0018]
【表3】 [Table 3]
【0019】[0019]
【製法】参考例1と同様の製法で製した。[Production method] The same production method as in Reference example 1 was used.
【0020】[0020]
【表4】 [Table 4]
【0021】[0021]
【製法】参考例1と同様の製法で製した。[Production method] The same production method as in Reference example 1 was used.
【0022】[0022]
【表5】 [Table 5]
【0023】[0023]
【製法】参考例1と同様の製法で製した。[Production method] The same production method as in Reference example 1 was used.
【0024】[0024]
【表6】 [Table 6]
【0025】[0025]
【製法】40℃の混合機内で,ガムベース,粉糖,ブド
ウ糖,水飴,オレンジオイル,シソ葉エキスを均質に混
合後,シート状に圧延した。冷却後,15×70mmに切断し
た。[Production method] In a mixer at 40 ° C, gum base, powdered sugar, glucose, starch syrup, orange oil and perilla leaf extract were mixed homogeneously and then rolled into a sheet. After cooling, it was cut to 15 x 70 mm.
【0026】[0026]
【表7】 [Table 7]
【0027】[0027]
【製法】参考例2と同様の製法で製した。[Production method] The same production method as in Reference example 2 was used.
【0028】[0028]
【表8】 [Table 8]
【0029】[0029]
【製法】参考例2と同様の製法で製した。[Production method] The same production method as in Reference example 2 was used.
【0030】[0030]
【表9】 [Table 9]
【0031】[0031]
【製法】砂糖,水飴,練乳,小麦粉,バター,水を60
℃に加温して溶解し1時間撹拌後122℃まで煮詰めシ
ソ葉エキスとミルクフレバーを添加混合後50℃迄冷却
し, 圧延,裁断した。[Production method] Sugar, starch syrup, condensed milk, flour, butter, water 60
The mixture was heated to ℃ to dissolve, stirred for 1 hour, boiled down to 122 ° C, mixed with perilla leaf extract and milk flavor, cooled to 50 ° C, rolled and cut.
【0032】[0032]
【表10】 [Table 10]
【0033】[0033]
【製法】参考例3と同様の製法で製した。[Production method] The same production method as in Reference example 3 was used.
【0034】[0034]
【表11】 [Table 11]
【0035】[0035]
【製法】参考例3と同様の製法で製した。[Production method] The same production method as in Reference example 3 was used.
【0036】これらについて,前述のマウス自発運動量
抑制試験を行った結果を表12に示した。シソ葉エキス
投与群とクチナシエキス投与群は共に対照群に対し有意
なマウス自発運動抑制が見られた(t−テストで危険率
5%未満)。Table 12 shows the results of the mouse locomotor activity suppression test described above. Both the perilla leaf extract-administered group and the gardenia extract-administered group showed significant suppression of spontaneous locomotor activity in the control group compared to the control group (t-test: risk rate less than 5%).
【0037】[0037]
【表12】 [Table 12]
【0038】次に参考例1、実施例1〜2および比較例
1について、ハードキャンディ1個を喫食後、前述官能
試験を行った際の、20人の平均値を、表13に示す。Next, for Reference Example 1 , Examples 1 and 2, and Comparative Example 1, after eating one hard candy and performing the above-mentioned sensory test, the average value of 20 persons is shown in Table 13.
【0039】[0039]
【表13】 [Table 13]
【0040】表13からわかる通り、実施例1〜2は植
物エキスを含まない比較例1に比べ喫食後気分が落ち着
いたと評価した。美味しさも比較例にはやや劣るものの
美味しいと評価された。As can be seen from Table 13, Examples 1 and 2 were evaluated as calming after eating compared with Comparative Example 1 containing no plant extract. The taste was also evaluated as delicious, although slightly inferior to the comparative examples.
【0041】[0041]
【発明の効果】以上の様に、本発明のクチナシを含有せ
しめた食品は良好な風味を有しストレス等の軽度の精神
疲労に対する緩和作用を持つと言う利点を有する。しか
も、食し易いので喫食者が楽しみながら、適当な量を摂
取することができる。As described above, the food containing the gardenia of the present invention has an advantage that it has a good flavor and has an action of alleviating mild mental fatigue such as stress. Moreover, since the food is easy to eat, the user can enjoy an appropriate amount while enjoying the food.
───────────────────────────────────────────────────── フロントページの続き (56)参考文献 Chem Pharm Bull.v ol.34,no.4,p1672−1677 (1986) Int J Crude Drug Res,vol.23,no4,p221− 227(1988) (58)調査した分野(Int.Cl.7,DB名) A61K 35/78 A23L 1/30 A61P 25/20 BIOSIS(DIALOG) CA(STN) MEDLINE(STN)──────────────────────────────────────────────────続 き Continued on the front page (56) References Chem Pharm Bull. vol. 34, no. 4, p1672-1677 (1986) Int J Crude Drug Res, vol. 23, no4, p221-227 (1988) (58) Fields investigated (Int. Cl. 7 , DB name) A61K 35/78 A23L 1/30 A61P 25/20 BIOSIS (DIALOG) CA (STN) MEDLINE (STN)
Claims (1)
とする精神安定用食品。1. A tranquilizer food comprising a gardenia extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3242503A JP3059795B2 (en) | 1991-08-27 | 1991-08-27 | Mental stability food |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3242503A JP3059795B2 (en) | 1991-08-27 | 1991-08-27 | Mental stability food |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0558904A JPH0558904A (en) | 1993-03-09 |
| JP3059795B2 true JP3059795B2 (en) | 2000-07-04 |
Family
ID=17090069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3242503A Expired - Fee Related JP3059795B2 (en) | 1991-08-27 | 1991-08-27 | Mental stability food |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3059795B2 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2753686B2 (en) * | 1994-09-02 | 1998-05-20 | 工業技術院長 | Blood coagulation inhibitors and functional foods |
| JPH0873371A (en) * | 1994-09-02 | 1996-03-19 | Agency Of Ind Science & Technol | Suppressant for cancer metastasis and its production |
| KR100353262B1 (en) * | 2000-03-15 | 2002-09-18 | 주식회사 한국야쿠르트 | Perilla frutescence extract Method which effects to prevention and treatment of a stomach ulcer and its use and process of obtaining for berberine therefrom |
| JP2001322939A (en) * | 2000-05-11 | 2001-11-20 | Ichimaru Pharcos Co Ltd | Agent for preventing and ameliorating skin roughening due to stress |
| JP6263349B2 (en) * | 2013-08-27 | 2018-01-17 | 国立大学法人広島大学 | Antiallergic substances and method for producing the same |
-
1991
- 1991-08-27 JP JP3242503A patent/JP3059795B2/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| Chem Pharm Bull.vol.34,no.4,p1672−1677(1986) |
| Int J Crude Drug Res,vol.23,no4,p221−227(1988) |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0558904A (en) | 1993-03-09 |
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