JP2018171349A - Medical tubular member, foreign substance removal device, and foreign substance removal catheter - Google Patents

Abstract

[PROBLEMS] To provide a medical tubular member that can be smoothly bent and can prevent the occurrence of breakage or deformation when bent, a foreign substance removing device including the medical tubular member, and a foreign substance removing catheter. provide. A cylindrical medical tubular member to be inserted into a tubular tissue such as a blood vessel, wherein a plurality of slits 20 are formed along the direction intersecting the axis X direction through the tube wall of the medical tubular member. In each of the slits 20, the edge portions 22 facing each other on both end sides in the extending direction are gradually approached toward the end portion to narrow the width, and both end portions (hole portions 21) are round hole shapes. It swells to form. [Selection] Figure 3

Description

  The present invention relates to a medical tubular member, a foreign substance removing device, and a foreign substance removing catheter.

  Conventionally, as a medical tubular member inserted into a tubular tissue such as a blood vessel, for example, a thrombus removing device for removing a thrombus from a blood vessel wall is known (see, for example, Patent Document 1).

JP-T-2006-513524

By the way, when inserting the thrombectomy device to a predetermined position where the thrombus exists without damaging the blood vessel wall of the thin and winding blood vessel, it is desirable that the thrombus removal device has a structure that can be bent smoothly.
Therefore, it is conceivable to form a plurality of slits in the thrombus removal device, but when bent, stress concentrates on the ends of the slits, causing damage such as cracks, or the opposing edges of the slits partially When the contact is made, the load may be concentrated on the contacted portion and the deformation may occur.

  Such a problem can also occur in a tubular member inserted into a tubular tissue other than a blood vessel (eg, digestive tract, bile duct, etc.).

  The present invention has been made in view of the above-described circumstances, and the purpose thereof is a medical tubular member that can be smoothly bent and can be prevented from being damaged or deformed when bent, An object of the present invention is to provide a foreign substance removing device and a foreign substance removing catheter provided with the medical tubular member.

In order to achieve the above-described object, a medical tubular member, a foreign substance removing device, and a foreign substance removing catheter according to the present invention are characterized by the following (1) to (7).
(1) A tubular medical tubular member inserted into a tubular tissue,
A plurality of slits are formed along the direction intersecting the axial direction through the tube wall of the medical tubular member,
Each of the plurality of slits is
Edges facing each other on both end sides in the extending direction are gradually approached toward the end portion to reduce the width,
The medical tubular member, wherein the both end portions swell so as to form a round hole shape.
(2) The medical tubular member according to (1), wherein the slit exists on a straight line substantially parallel to the axial direction at any position in the circumferential direction.
(3) The tubular member for medical use according to (1) or (2), wherein the plurality of slits are arranged so as to spiral in the circumferential direction.
(4) The tubular member for medical use according to (1) or (2), wherein the plurality of slits are arranged such that adjacent ones in the axial direction are shifted in the circumferential direction.
(5) The medical tubular member according to any one of (1) to (4), wherein the medical tubular member is provided on an insertion direction front side and an insertion direction rear side of a member to be inserted inserted into the tubular tissue.
(6) A foreign matter removing device configured to be able to remove or collect foreign matter in the tubular tissue,
Comprising a tubular tubular member inserted into the tubular tissue;
In the tubular member, a plurality of slits are formed along the direction intersecting the axial direction, penetrating the tube wall,
Each of the plurality of slits is
Edges facing each other on both end sides in the extending direction are gradually approached toward the end portion to reduce the width,
The foreign matter removing device, wherein the both end portions swell so as to form a round hole shape.
(7) A foreign matter removing catheter for removing or collecting foreign matter in a tubular tissue,
A catheter body;
A foreign substance removing device disposed at a distal portion of the catheter body and configured to remove or collect foreign substances in the tubular tissue,
The foreign matter removing device is
Comprising a tubular tubular member inserted into the tubular tissue;
In the tubular member, a plurality of slits are formed along the direction intersecting the axial direction, penetrating the tube wall,
Each of the plurality of slits is
Edges facing each other on both end sides in the extending direction are gradually approached toward the end portion to reduce the width,
The foreign substance removing catheter, wherein the both end portions swell so as to form a round hole shape.

According to the medical tubular member having the configuration (1), a plurality of slits are formed along the direction intersecting the axial direction through the tube wall of the medical tubular member. Even if the tubular tissue is curved, it can be bent smoothly in the tubular tissue. In addition, since both end portions in the extending direction of the slit swell so as to form a round hole shape, stress generated on the end side when bent, particularly stress concentrated on the end portion, is dispersed to the periphery. Damage such as cracks at the part can be suppressed. Furthermore, since the edges facing each other on the both end sides of the slit are gradually approached toward the end and the width is narrowed, the edges facing each other on the both end sides of the slit are easily adhered to each other, It is possible to suppress deformation that occurs when the edge of the slit partially abuts and the load concentrates on the abutted portion.
According to the medical tubular member having the configuration of the above (2), since the slit exists on a straight line substantially parallel to the axial direction at any position in the circumferential direction, the axial direction can be achieved at any position in the axial direction. Can be smoothly bent in any direction that intersects with, and high flexibility can be obtained.
According to the medical tubular member having the configuration of (3) above, the plurality of slits are arranged so as to be spirally connected in the circumferential direction, thereby increasing the degree of freedom of bending and in any direction that more smoothly intersects the axial direction. Can be bent.
According to the medical tubular member having the configuration of the above (4), since the adjacent ones in the axial direction of the plurality of slits are shifted in the circumferential direction, the degree of freedom in bending is increased, and the axial direction is smoother. Can be bent in any direction that intersects.
According to the medical tubular member having the configuration of the above (5), the tubular tissue is provided even if the tubular tissue is curved by providing the medical tubular member on the insertion direction front side and the insertion direction rear side of the inserted member. The medical tubular member of the inserted member to be inserted into can be smoothly bent, and the inserted member can be smoothly conveyed to a predetermined position in the tubular tissue.
According to the foreign substance removal device having the configuration of (6) above, not only the same effects as in (1) can be obtained, but also when inserting the foreign substance removal device into a predetermined position that requires removal or recovery of the foreign substance in the tubular tissue, Even if the tubular tissue is curved, the medical tubular member of the foreign substance removing device can be smoothly bent, and the foreign substance removing device can be smoothly conveyed to a predetermined position in the tubular tissue. Thereby, the foreign material in a tubular structure | tissue can be easily removed or collect | recovered.
According to the foreign substance removing catheter configured as described in (7) above, not only the same effects as in (1) can be obtained, but also the foreign substance removing device can be smoothly formed into a tubular tissue in substantially the same manner as the foreign substance removing device of the present invention described above. It is possible to easily remove or collect foreign matter in the tubular tissue by inserting it into a predetermined position that requires removal or collection of the foreign matter.

  According to the present invention, it can be bent smoothly, and it is possible to suppress the occurrence of breakage or deformation when bent.

  The present invention has been briefly described above. Further, the details of the present invention will be further clarified by reading through a mode for carrying out the invention described below (hereinafter referred to as “embodiment”) with reference to the accompanying drawings. .

1A and 1B are diagrams for explaining a medical tubular member according to the present embodiment, in which FIG. 1A is a side view of the medical tubular member, and FIG. 1B is a partial view of FIG. It is an enlarged view. FIG. 2 is a diagram showing the shape of the slit formed in the medical tubular member according to the present embodiment. FIG. 3 is a diagram schematically showing the arrangement of the slits of the medical tubular member according to the present embodiment. FIG. 4 is a side view of the medical tubular member according to the present embodiment in a bent state. FIG. 5 is a side view of the medical tubular member according to the reference example in a bent state. FIG. 6 is a schematic configuration diagram illustrating the foreign substance removing catheter according to the present embodiment. 7A and 7B are views showing the internal structure of the foreign substance removing catheter according to the present embodiment. FIG. 7A is a sectional view when the retriever is expanded, and FIG. 7B is a sectional view when the retriever is contracted. It is. FIG. 8 is a view for explaining a method of using the foreign substance removing catheter, and FIGS. 8A to 8F are schematic cross-sectional views at the foreign substance removing position in the tubular tissue, respectively. FIG. 9 is a diagram schematically showing the arrangement of slits in the medical tubular member according to the modification. FIG. 10 is a diagram showing the shape of another slit formed in the medical tubular member.

  Hereinafter, an example of an embodiment according to the present invention will be described with reference to the drawings.

(Tubular member for medical use)
1A and 1B are diagrams for explaining a medical tubular member according to the present embodiment, in which FIG. 1A is a side view of the medical tubular member, and FIG. 1B is a partial view of FIG. It is an enlarged view.

  As shown in FIGS. 1A and 1B, a medical tubular member (hereinafter simply referred to as a tubular member) 10 according to the present embodiment is, for example, a pipe-shaped member having a circular cross section. The tubular member 10 is a member that is inserted into a tubular tissue such as a blood vessel.

  Examples of the material constituting the tubular member 10 include stainless steel, titanium alloy, Ni—Ti alloy, Ni—Ti—Co alloy, Ni—Ti—Cu alloy, Au—Cd alloy, and Cu—Al—Ni alloy. The well-known metal or metal alloy represented can be used preferably. Moreover, it is good also as a radiopaque marker by using the alloy which has X-ray contrast property as a material. In this case, the position of the tubular member 10 can be confirmed from outside the body.

A plurality of slits 20 are formed in the tube wall 11 of the tubular member 10. These slits 20 are formed by penetrating the tube wall 11 of the tubular member 10 inward and outward, for example, by laser processing. The plurality of slits 20 are formed along the direction intersecting the axis X direction of the tubular member 10. Specifically, the plurality of slits 20 have substantially the same shape and dimensions, and are formed so as to be spiraled in the circumferential direction (details will be described later; see FIG. 3).
In addition, as a processing method of the slit 20, for example, laser processing can be preferably used, but it may be formed by other processing methods.

FIG. 2 is a diagram showing the shape of the slit formed in the medical tubular member according to the present embodiment.
As shown in FIG. 2, holes 21 swelled so as to form a round hole shape (for example, a circular shape in plan view) are formed at both ends of the slit 20.
Specifically, it is preferable that the diameter, the center position, and the like of the hole 21 are defined so that the area is larger than, for example, a semicircle when the hole 21 is assumed to be circular. That is, for example, the diameter when the hole 21 is assumed to be circular is larger than the width of the narrowest portion of the edge portions 22 (described later) of the slit 20 facing each other, and the center of the hole 21 It is preferable that the positions are arranged outside the edge portions 22 facing each other (upper side and lower side in FIG. 2).
In addition, although illustration is abbreviate | omitted, with respect to the width | variety of the narrowest part of the edge part 22, the diameter at the time of assuming the hole 21 as circular may be substantially equal.

Further, the slit 20 is formed in a shape in which the edge portions 22 facing each other are gradually narrowed from the center side toward the end portion. Specifically, the edge portions 22 of the slit 20 facing each other have the widest width at the substantially central portion in the extending direction of the slit 20. For example, the width of the substantially central portion is larger than the diameter when the hole 21 is assumed to be circular. Further, the edge portions 22 of the slit 20 facing each other extend linearly so as to incline at substantially the same angle with respect to the extending direction, with the substantially central portion in the extending direction of the slit 20 as a boundary. That is, the edge portions 22 that face each other are inclined so as to form a substantially “C” shape on each end side with respect to a substantially central portion in the extending direction of the slit 20.
In addition, the edge part 22 which the slit 20 mutually opposes may be formed in substantially arc shape, for example.

  The tubular member 10 is, for example, a pipe having an outer diameter of 1.6 mm (inner diameter 1.4 mm) to an outer diameter of about 2.45 mm (inner diameter 2.05 mm). Moreover, the diameter of the hole 21 at both ends of the slit 20 formed in the tubular member 10 is, for example, 0.14 mm. The hole 21 preferably has a diameter of 0.08 mm or more and 0.20 mm or less.

FIG. 3 is a diagram schematically showing the arrangement of the slits of the medical tubular member according to the present embodiment.
As shown in FIG. 3, the slit 20 is formed to be slightly inclined with respect to the straight line A orthogonal to the axis X. The plurality of slits 20 have the same shape and the same dimensions. Thereby, in the tubular member 10, the slits 20 are formed so as to be spirally connected in the circumferential direction, and the inter-slit region portion 24 between the slits 20 spirally connected to each other in the circumferential direction is spirally arranged. . And the slit 20 is arrange | positioned so that the slit 20 may exist on the straight line B substantially parallel to the axis line X direction in any position of the circumferential direction of the tubular member 10. The plurality of slits 20 may have different shapes from each other and may have different dimensions.

FIG. 4 is a side view of the medical tubular member according to the present embodiment in a bent state.
As shown in FIG. 4, the tubular member 10 having a plurality of slits 20 along the direction intersecting the axis X direction opens the slit 20 on the extending side (upper side in FIG. 4) when a bending force is applied. In addition, the slit 20 is closed on the side to be bent (the lower side in FIG. 4).

  As described above, according to the medical tubular member 10 according to the present embodiment, by having the plurality of slits 20 along the direction intersecting the axis X direction, good flexibility is provided, and the blood vessel that is thin and tortuous is provided. However, it is bent along the shape and inserted smoothly without damaging the blood vessel wall.

Here, a tubular member 10A according to a reference example having straight slits 20 without holes 21 at both ends will be described with reference to FIG.
FIG. 5 is a side view of the medical tubular member according to the reference example in a bent state.

  As shown in FIG. 5, in the tubular member 10 </ b> A according to this reference example, since there is no hole portion 21 at both ends of the slit 20, the slit 20 is torn due to stress concentrated on both ends of the slit 20 to be opened on the extending side. Damage may occur. Further, on the bent side, a gap is generated between the edge portions 22 of the slit 20, and the edge portions 22 of the slit 20 are partially in contact with each other, and a load acts on the contacted portion in a concentrated manner. May cause deformation.

  On the other hand, according to the tubular member 10 according to the present embodiment, since both ends in the extending direction of the slit 20 swell so as to form a round hole shape, stress generated on the end side when bent, particularly The stress concentrated on the end portion is dispersed to the periphery, and breakage such as a crack at the end portion can be suppressed. Further, since the edges facing each other on both ends of the slit 20 are gradually approached toward the ends and the width is narrowed, the edges 22 facing each other on both ends of the slit 20 are in close contact with each other. It becomes easy and the edge part 22 of the slit 20 contact | abuts partially, and the deformation | transformation which arises when a load concentrates on the contacted part can be suppressed.

  Moreover, according to the medical tubular member 10 according to the present embodiment, since the slit 20 exists on the straight line B substantially parallel to the axis X direction at any position in the circumferential direction, at any position in the axis X direction. However, it can be smoothly bent in any direction crossing the direction of the axis X, and high flexibility can be obtained.

  Moreover, according to the medical tubular member 10 which concerns on this embodiment, it arrange | positions so that the slit 20 may be continued spirally in the circumferential direction. Thereby, the freedom degree of a bending can be raised and it can bend | curved in all the directions which cross | intersect an axis line X direction more smoothly.

  Moreover, according to the medical tubular member 10 according to the present embodiment, for example, the medical tubular member 10 can be provided on the insertion direction front side and the insertion direction rear side of the inserted member inserted into a tubular tissue such as a blood vessel. In this case, even if the tubular tissue is curved, the medical tubular member 10 to be inserted into the tubular tissue can be smoothly bent, and the inserted member can be smoothly conveyed to a predetermined position in the tubular tissue. be able to.

(Foreign substance removal device, foreign body removal catheter)
Next, the foreign substance removing device and the foreign substance removing catheter provided with the medical tubular member 10 will be described.
FIG. 6 is a schematic configuration diagram illustrating the foreign substance removing catheter according to the present embodiment. 7A and 7B are views showing the internal structure of the foreign substance removing catheter according to the present embodiment. FIG. 7A is a sectional view when the retriever is expanded, and FIG. 7B is a sectional view when the retriever is contracted. It is.

  As shown in FIG. 6, the foreign substance removing catheter 50 includes a catheter main body 60, a foreign substance removing device 100 arranged at the distal portion of the catheter main body 60, and an operation unit 70 arranged at the proximal portion of the catheter main body 60. With.

  In this specification, the “distal portion” refers to a region on the side of the end farther from the user of the foreign substance removal catheter 50, and the “proximal portion” refers to the use of the foreign substance removal catheter 50. This refers to the region on the end side (near side) closer to the user.

  The foreign substance removal catheter 50 is, for example, a thrombus removal catheter for removing or collecting a foreign substance such as a thrombus or an embolus generated in a blood vessel by the foreign substance removal device 100.

  The foreign matter removing device 100 includes the tubular member 10 according to the present embodiment described above and a retriever 120 provided on the tubular member 10. The retriever 120 is a member to be inserted into the tubular tissue, and can be expanded and contracted.

  Moreover, although description by illustration is abbreviate | omitted, the tubular member 10 and the retriever 120 can be formed by carrying out the laser processing of one metal pipe (for example, pipe consisting of a Ni-Ti alloy). In this case, the tubular member 10 and the retriever 120 can be integrally formed.

  The tubular member 10 has a distal tubular member 10F on the distal side with respect to the retriever 120 and a proximal tubular member 10N on the proximal side with respect to the retriever 120.

  As shown in FIGS. 7A and 7B, the catheter body 60 includes a first tube 62 extending from the distal portion to the proximal portion of the catheter body 60, the foreign substance removing device 100, and the operation portion 70. And a second tube 64 to be connected. The first tube 62 is provided with a guide wire lumen for inserting the guide wire.

  An end of the distal tubular member 10 </ b> F constituting the foreign substance removal device 100 is connected to the outer peripheral surface of the distal portion of the first tube 62. The proximal end of the proximal tubular member 10 </ b> N constituting the foreign substance removal device 100 is connected to the inner peripheral surface of the distal portion of the second tube 64. The inner diameter of the second tube 64 is set larger than the outer diameter of the first tube 62, and a gap with a predetermined dimension is provided between the first tube 62 and the second tube 64.

  Both the first tube 62 and the second tube 64 are formed of a flexible material. Examples of the flexible material include a synthetic resin (elastomer), a resin compound in which another material is mixed with a synthetic resin, a multilayer structure in which the synthetic resin is composed of multiple layers, or a composite of a synthetic resin and a metal wire. Etc. can be preferably used.

  The operation unit 70 includes, for example, a stick-shaped (bar-shaped) operation unit main body 72, a slider 76 installed on a side surface of the operation unit main body 72, and a liquid filling port 78 provided on the side surface of the operation unit main body 72.

  A long hole 74 extending in the longitudinal direction (tube axis direction) is provided on the side surface of the operation unit main body 72. The slider 76 is connected to the first tube 62 through the long hole 74, and is configured to be movable in parallel along the longitudinal direction (tube axis direction).

  The liquid filling port 78 communicates with the internal lumen of the second tube 64 (a gap between the first tube 62 and the second tube 64), and, for example, physiological saline or the like enters the catheter body 60 via the liquid filling port 78. The liquid can be filled. In addition, although description by illustration is abbreviate | omitted, the opening edge part of the liquid filling port 78 is liquid-tightly closed by the sealing body, such as a cap, or the valve body which consists of silicon rubbers.

  Here, the movement of the foreign substance removal device 100 when the slider 76 is moved will be described with reference to FIGS. 7 (a) and 7 (b).

  First, when the slider 76 is moved in the arrow X1 direction in the state shown in FIG. 7A, the first tube 62 connected to the slider 76 is also moved in the X1 direction. At this time, the connection position between the first tube 62 and the foreign substance removal device 100 moves in the X1 direction, but the connection position between the first tube 62 and the second tube 64 does not change. That is, as a result of the first tube 62 moving relative to the second tube 64 in the X1 direction, the retriever 120 contracts (see FIG. 7B).

  On the other hand, when the slider 76 is moved in the arrow X2 direction in the state shown in FIG. 7B, the first tube 62 connected to the slider 76 is also moved in the X2 direction. At this time, the connection position between the first tube 62 and the foreign substance removal device 100 moves in the X2 direction, but the connection position between the first tube 62 and the second tube 64 does not change. That is, as a result of the first tube 62 moving relative to the second tube 64 in the X2 direction, the retriever 120 expands (see FIG. 7A).

  That is, the expansion / contraction of the retriever 120 can be manipulated by translating the slider 74 along the longitudinal direction (tube axis direction).

  Next, an example of how to use the foreign substance removing catheter 50 will be described with reference to FIG.

  FIG. 8 is a view for explaining a method of using the foreign substance removing catheter, and FIGS. 8A to 8F are schematic cross-sectional views at the foreign substance removing position in the tubular tissue, respectively. In FIGS. 8A to 8F, the shape and the like of each member constituting the foreign substance removal catheter 50 are schematically shown in order to facilitate understanding of the invention.

  First, as shown in FIG. 8 (a), a guiding catheter GC is inserted into the blood vessel along the guide wire W while the guide wire W is passed through the blood vessel, and a target site (foreign matter) at a predetermined position is inserted. The foreign substance removing catheter 50 is delivered to the front of the site where CL is present.

  Next, as shown in FIG. 8 (b), the foreign substance removing catheter 50 is sent out from the guiding catheter GC, and the foreign substance CL is penetrated in a state where the retriever 120 is contracted, so that the retriever 120 is distant from the target site. To place.

  Next, as shown in FIG. 8C, in a state where the retriever 120 is expanded, the foreign substance removal catheter 50 is pulled toward the hand side, and the foreign substance CL is entangled with the retriever 120 (see FIG. 8D). . In order to entangle the retriever 120 with the foreign material CL, for example, the retriever 120 may be rotated around the tube axis at the target site, the retriever 120 may be advanced / retracted at the target site, or the retriever 120 may be moved at the target site. May be expanded / contracted.

  Then, as shown in FIG. 8E, the retriever 120 is contracted while the foreign object CL is entangled, and the retriever 120 (foreign substance removal catheter 50) is drawn into the guiding catheter GC (see FIG. 8F). ). Thereafter, the foreign substance CL can be taken out of the body percutaneously by performing the operation of extracting the foreign substance removing catheter 50 from the inside of the guiding catheter GC.

  As described above, according to the foreign substance removal device 100 according to the present embodiment, not only the same effect as the medical tubular member 10 described above is obtained, but also the removal or collection of foreign substances in a tubular tissue such as a blood vessel is performed. The foreign substance removal device 100 can be smoothly transported to the required predetermined position. Thereby, the foreign material in a tubular structure | tissue can be easily removed or collect | recovered.

  Moreover, according to the foreign substance removal catheter 50 according to the present embodiment, not only the same effect as the medical tubular member 10 described above can be obtained, but the foreign substance removal device 100 can be provided in substantially the same manner as the foreign substance removal device 100 described above. The foreign matter in the tubular tissue such as a blood vessel can be smoothly inserted into a predetermined position where the removal or recovery is required, and the foreign matter in the tubular tissue can be easily removed or recovered.

  In addition, this invention is not limited to what was illustrated by the said embodiment, In the range which does not deviate from the summary of this invention, it can implement in a various aspect, For example, the following deformation | transformation is also possible. is there.

In the above-described embodiment, the slits 20 of the tubular member 10 are formed so as to be slightly inclined with respect to the straight line A orthogonal to the axis X and to be spirally connected in the circumferential direction, and the slits 20 that are spirally continuous in the circumferential direction are mutually connected. Although the case where the inter-slit region portion 24 between them is arranged spirally has been described as an example, the present invention is not limited to this.
For example, as shown in FIG. 9, the slits 20 are formed so as to be continuous in the circumferential direction along the straight line A orthogonal to the axis X at a plurality of positions spaced in the direction of the axis X, and are slits 20 continuous in the circumferential direction. The inter-slit region portions 24 between each other may be alternately arranged in the axis X direction. Also in this case, it is possible to increase the degree of freedom of bending and bend in any direction that intersects the axis X direction more smoothly.

  In addition, you may vary the space | interval (repetitive pitch) of the adjacent things in the some slit 20 with the position of the axial direction of the tubular member 10, for example. Specifically, for example, the flexibility may be changed by changing the pitch between the distal end portion of the tubular member 10 and the proximal end portion on the opposite side, or from the proximal end to the distal end. It may be made easier to bend toward the tip side by changing the pitch stepwise toward the side.

As the shape of the slit 20, for example, as shown in FIG. 10, linear edge portions 22 are arranged in parallel in the center region 20 </ b> A, and in the both end regions 20 </ b> B, the shape is linear from the center side to the end portion. The edge portions 22 may be gradually brought closer to each other and the width may be gradually narrowed.
Further, in the slit 20, even if the hole portion 21 is not continuous with the portion that is gradually approached toward the end portion of the edge portion 22 facing each other on both end sides in the extending direction and the width thereof is narrowed. Good. For example, although illustration is omitted, a parallel portion having a constant width is formed continuously with a portion that is gradually closer to the edge 22 and narrowed, and the hole 21 is formed continuously with the parallel portion. It may be formed.

  In addition, the material, shape, and the like of the tubular member 10 illustrated in the above embodiment are merely examples and are not limited thereto, and can be arbitrarily changed as appropriate. That is, although the case where the tubular member 10 is a metal material was illustrated and demonstrated, this invention is not limited to this, For example, resin, wood, etc. may be sufficient. Moreover, although the case where the cross-sectional shape of the tubular member 10 is circular was illustrated and demonstrated, this invention is not limited to this, For example, an ellipse may be sufficient and it may be a polygon. Also good.

  Moreover, in the said embodiment, although the case where the hole 21 of the both ends of the slit 20 was circular was illustrated and demonstrated, this invention is not limited to this, For example, elliptical shape etc. Also good.

  Moreover, in the said embodiment, although the case where the tubular member 10 and the retriever 120 were integrally formed was demonstrated and demonstrated, this invention is not limited to this, The tubular member 10 and the retriever 120 are included. After forming each as a separate body, the tubular member 10 and the retriever 120 may be joined by means such as adhesion or welding.

  Moreover, in the said embodiment, although the case where the tubular tissue used as a usage object was a blood vessel was illustrated and demonstrated, this invention is not limited to this. For example, a tubular member 10 inserted into another tubular tissue such as the digestive tract or bile duct, a foreign substance removal device 100 for removing or collecting foreign matter generated inside another tubular tissue such as the digestive tract or bile duct, The present invention can also be applied to the foreign substance removing catheter 50.

(Evaluation test)
Various evaluation tests were performed on various tubular members in which slits were arranged so as to be continuous in a spiral manner, and an inter-slit region between end portions of each slit was spirally arranged.

(1) Evaluation sample Tubular members of Examples 1 to 3 and Comparative Example 1 described below in which various slits were formed in a pipe made of a Ni—Ti alloy having an outer diameter of 1.75 mm and an inner diameter of 1.45 mm were evaluated.
The tubular members of Examples 1 to 3 are formed with slits that have holes at both ends, and edges that face each other at both ends in the extending direction are gradually approached toward the ends and become narrower. ing. The diameter of the hole is 0.08 mm in Example 1, 0.14 mm in Example 2, and 0.20 mm in Example 3.
The tubular member of Comparative Example 1 is formed with straight slits having no holes at both ends.

(2) Test content (2-1) Flexibility test A tubular member is supported at intervals of 30 mm, a load is applied to the center of the tubular member, and the load is pushed in by 2 mm, and the load is measured. The measurement is performed three times for each tubular member, and the average value is calculated.
(2-2) Bending test A bent tubular member is sandwiched between two opposing flat plates, the distance between the flat plates is reduced, and the radius of curvature of the bent portion at the time of fracture of the tubular member is measured. The measurement is performed three times for each tubular member, and the average value is calculated.
(2-3) Tensile test Each tubular member is pulled with a tensile tester at a pulling speed of 10 mm / min, and the tensile strength until breaking is measured. The measurement is performed three times for each tubular member, and the average value is calculated.

(3) Evaluation results Table 1 shows the results of each evaluation test.

(3-1) Flexibility test The average load when each tubular member was pushed in was 1.37N in Example 1, 1.14N in Example 2, 0.80N in Example 3, and 1.1 in Comparative Example 1. 68N. Thus, it was confirmed that Examples 1-3 which have a hole part in the both ends of a slit require less bending force than Comparative Example 1 which does not have a hole part in both ends of a slit, and a flexibility improves. . Moreover, it was confirmed that the larger the diameter of the hole portion, the more the flexibility is improved.
(3-2) Bending test The average curvature radius of each tubular member was 2.08 mm in Example 1 and 3.53 mm in Comparative Example 1, and no breakage occurred in Example 2 and Example 3. Thus, by providing holes at both ends of the slit, the radius of curvature that breaks by bending as in Example 1 is smaller than in Comparative Example 1 in which there are no holes at both ends of the slit. As in 2 and 3, it was confirmed that when the diameter of the hole is 0.14 mm or more, breakage due to bending does not occur.
(3-3) Tensile test The average tensile strength of each tubular member was 40.9N in Example 1, 38.0N in Example 2, 27.3N in Example 3, and 46.7N in Comparative Example 1. . In Examples 1 to 3 having holes at both ends of the slit, it was confirmed that sufficient tensile strength was obtained although the tensile strength was somewhat reduced as compared with Comparative Example 1 having no holes at both ends of the slit.

  From the result of the above evaluation test, by providing holes with a diameter of 0.08 mm or more and 0.20 mm or less at both ends of the slit formed in the tubular member, the flexibility is improved while suppressing breakage and deformation in the slit. In particular, it is confirmed that by providing a hole portion having a diameter of 0.14 mm at both ends of the slit, the effect of suppressing breakage and deformation in the slit of the tubular member and the improvement in flexibility can be further enhanced. did it.

10: Medical tubular member 11: Tube wall 20: Slit 21: Hole 22: Edge 24: Inter-slit region 50: Foreign substance removal catheter 60: Catheter body 70: Operation unit 100: Foreign substance removal device 120: Retriever ( Inserted member)
B: Straight line CL: Foreign object X: Axis

Claims (7)

A cylindrical medical tubular member inserted into a tubular tissue,
A plurality of slits are formed along the direction intersecting the axial direction through the tube wall of the medical tubular member,
Each of the plurality of slits is
Edges facing each other on both end sides in the extending direction are gradually approached toward the end portion to reduce the width,
The medical tubular member, wherein the both end portions swell so as to form a round hole shape. The medical tubular member according to claim 1, wherein the slit exists on a straight line substantially parallel to the axial direction at any position in the circumferential direction. The medical slit member according to claim 1 or 2, wherein the plurality of slits are arranged so as to be spirally connected in a circumferential direction. The medical tubular member according to claim 1 or 2, wherein the plurality of slits are arranged such that adjacent ones in the axial direction are shifted in the circumferential direction. The medical tubular member according to any one of claims 1 to 4, wherein the medical tubular member is provided on an insertion direction front side and an insertion direction rear side of a member to be inserted inserted into the tubular tissue. A foreign matter removal device configured to remove or collect foreign matter in a tubular tissue,
Comprising a tubular tubular member inserted into the tubular tissue;
In the tubular member, a plurality of slits are formed along the direction intersecting the axial direction, penetrating the tube wall,
Each of the plurality of slits is
Edges facing each other on both end sides in the extending direction are gradually approached toward the end portion to reduce the width,
The foreign matter removing device, wherein the both end portions swell so as to form a round hole shape. A foreign matter removing catheter for removing or collecting foreign matter in a tubular tissue,
A catheter body;
A foreign substance removing device disposed at a distal portion of the catheter body and configured to remove or collect foreign substances in the tubular tissue,
The foreign matter removing device is
Comprising a tubular tubular member inserted into the tubular tissue;
In the tubular member, a plurality of slits are formed along the direction intersecting the axial direction, penetrating the tube wall,
Each of the plurality of slits is
Edges facing each other on both end sides in the extending direction are gradually approached toward the end portion to reduce the width,
The foreign substance removing catheter, wherein the both end portions swell so as to form a round hole shape.