JP2013536841A5 - - Google Patents
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- JP2013536841A5 JP2013536841A5 JP2013527119A JP2013527119A JP2013536841A5 JP 2013536841 A5 JP2013536841 A5 JP 2013536841A5 JP 2013527119 A JP2013527119 A JP 2013527119A JP 2013527119 A JP2013527119 A JP 2013527119A JP 2013536841 A5 JP2013536841 A5 JP 2013536841A5
- Authority
- JP
- Japan
- Prior art keywords
- interleukin
- liquid
- receptor antagonist
- solid phase
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 101001076407 Homo sapiens Interleukin-1 receptor antagonist protein Proteins 0.000 claims description 22
- 229940119178 Interleukin 1 receptor antagonist Drugs 0.000 claims description 22
- 102000051628 Interleukin-1 receptor antagonist Human genes 0.000 claims description 22
- 239000003407 interleukin 1 receptor blocking agent Substances 0.000 claims description 22
- 210000004369 blood Anatomy 0.000 claims description 6
- 239000008280 blood Substances 0.000 claims description 6
- 239000011324 bead Substances 0.000 claims description 3
- 229920002401 polyacrylamide Polymers 0.000 claims description 3
- 210000000265 leukocyte Anatomy 0.000 claims 22
- 239000007788 liquid Substances 0.000 claims 22
- 238000000034 method Methods 0.000 claims 18
- 239000007790 solid phase Substances 0.000 claims 16
- 210000001519 tissue Anatomy 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 8
- 230000005672 electromagnetic field Effects 0.000 claims 5
- 238000002414 normal-phase solid-phase extraction Methods 0.000 claims 5
- 239000003795 chemical substances by application Substances 0.000 claims 4
- -1 polyethylene Polymers 0.000 claims 4
- 206010061218 Inflammation Diseases 0.000 claims 3
- 239000012530 fluid Substances 0.000 claims 3
- 230000004054 inflammatory process Effects 0.000 claims 3
- 229920000936 Agarose Polymers 0.000 claims 2
- 229920002307 Dextran Polymers 0.000 claims 2
- 239000004698 Polyethylene Substances 0.000 claims 2
- 239000004743 Polypropylene Substances 0.000 claims 2
- 239000004793 Polystyrene Substances 0.000 claims 2
- 229910000831 Steel Inorganic materials 0.000 claims 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims 2
- 108060008683 Tumor Necrosis Factor Receptor Proteins 0.000 claims 2
- 239000011805 ball Substances 0.000 claims 2
- 210000001185 bone marrow Anatomy 0.000 claims 2
- 210000002433 mononuclear leukocyte Anatomy 0.000 claims 2
- 229920000573 polyethylene Polymers 0.000 claims 2
- 229920001155 polypropylene Polymers 0.000 claims 2
- 229920002223 polystyrene Polymers 0.000 claims 2
- 229920000915 polyvinyl chloride Polymers 0.000 claims 2
- 239000004800 polyvinyl chloride Substances 0.000 claims 2
- 239000010453 quartz Substances 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- 239000010959 steel Substances 0.000 claims 2
- 239000010936 titanium Substances 0.000 claims 2
- 229910052719 titanium Inorganic materials 0.000 claims 2
- 102000003298 tumor necrosis factor receptor Human genes 0.000 claims 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 108010049003 Fibrinogen Proteins 0.000 claims 1
- 102000008946 Fibrinogen Human genes 0.000 claims 1
- 208000003076 Osteolysis Diseases 0.000 claims 1
- 108090000190 Thrombin Proteins 0.000 claims 1
- 210000000577 adipose tissue Anatomy 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 229940127219 anticoagulant drug Drugs 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 230000007717 exclusion Effects 0.000 claims 1
- 239000000835 fiber Substances 0.000 claims 1
- 229940012952 fibrinogen Drugs 0.000 claims 1
- 210000003918 fraction a Anatomy 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 208000029791 lytic metastatic bone lesion Diseases 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 150000002739 metals Chemical class 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 238000009987 spinning Methods 0.000 claims 1
- 229960004072 thrombin Drugs 0.000 claims 1
- 210000004623 platelet-rich plasma Anatomy 0.000 description 4
- 241000283073 Equus caballus Species 0.000 description 3
- 102000000589 Interleukin-1 Human genes 0.000 description 2
- 108010002352 Interleukin-1 Proteins 0.000 description 2
- 229960000074 biopharmaceutical Drugs 0.000 description 2
- 229940044551 receptor antagonist Drugs 0.000 description 2
- 239000002464 receptor antagonist Substances 0.000 description 2
- 238000012286 ELISA Assay Methods 0.000 description 1
- 238000008157 ELISA kit Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38002610P | 2010-09-03 | 2010-09-03 | |
| US61/380,026 | 2010-09-03 | ||
| PCT/US2011/048909 WO2012030593A2 (fr) | 2010-09-03 | 2011-08-24 | Méthodes et compositions permettant d'administrer un antagoniste du récepteur de l'interleukine 1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013536841A JP2013536841A (ja) | 2013-09-26 |
| JP2013536841A5 true JP2013536841A5 (fr) | 2014-01-09 |
Family
ID=44584662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013527119A Pending JP2013536841A (ja) | 2010-09-03 | 2011-08-24 | インターロイキン−１受容体アンタゴニストを送達するための方法および組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9119829B2 (fr) |
| EP (2) | EP2611456A2 (fr) |
| JP (1) | JP2013536841A (fr) |
| KR (1) | KR20140003398A (fr) |
| CN (1) | CN103249425A (fr) |
| AU (1) | AU2011296356B2 (fr) |
| CA (1) | CA2810202C (fr) |
| MX (1) | MX2013002488A (fr) |
| WO (1) | WO2012030593A2 (fr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
| US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
| US8034014B2 (en) | 2007-03-06 | 2011-10-11 | Biomet Biologics, Llc | Angiogenesis initation and growth |
| US8753690B2 (en) | 2008-02-27 | 2014-06-17 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
| EP2567692B1 (fr) | 2008-02-27 | 2016-04-06 | Biomet Biologics, LLC | Utilisation d'un dispositif pour obtenir des solutions riches en antagoniste de récepteur d'interleukine-1 |
| WO2011031553A2 (fr) | 2009-08-27 | 2011-03-17 | Biomet Biologics, Llc | Dispositif implantable pour la production d'antagoniste de récepteur d'interleukine-1 |
| EP2611456A2 (fr) | 2010-09-03 | 2013-07-10 | Biomet Biologics, LLC | Méthodes et compositions permettant d'administrer un antagoniste du récepteur de l'interleukine 1 |
| CA2825551A1 (fr) * | 2011-01-24 | 2012-08-02 | Progenicare, Llc | Compositions et procedes destines a favoriser la regeneration des tissus |
| US9011846B2 (en) | 2011-05-02 | 2015-04-21 | Biomet Biologics, Llc | Thrombin isolated from blood and blood fractions |
| WO2013114359A1 (fr) | 2012-01-31 | 2013-08-08 | Estar Technologies Ltd | Système et méthode de production d'un antagoniste du récepteur de l'interleukine (ira) |
| FR2987746B1 (fr) * | 2012-03-08 | 2015-04-10 | Adip Sculpt | Seringue pour application medicale |
| US9758806B2 (en) | 2013-03-15 | 2017-09-12 | Biomet Biologics, Llc | Acellular compositions for treating inflammatory disorders |
| US10208095B2 (en) * | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
| US20140271589A1 (en) * | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Treatment of collagen defects using protein solutions |
| US10143725B2 (en) * | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
| US9878011B2 (en) | 2013-03-15 | 2018-01-30 | Biomet Biologics, Llc | Treatment of inflammatory respiratory disease using biological solutions |
| US9895418B2 (en) * | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
| US9950035B2 (en) * | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
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| US20170128538A1 (en) * | 2014-06-30 | 2017-05-11 | Biomet Biologics, Llc | Methods for assessing the efficacy of anti-inflammatory cytokine compositions |
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| US10441635B2 (en) | 2014-11-10 | 2019-10-15 | Biomet Biologics, Llc | Methods of treating pain using protein solutions |
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| US11020603B2 (en) | 2019-05-06 | 2021-06-01 | Kamran Ansari | Systems and methods of modulating electrical impulses in an animal brain using arrays of planar coils configured to generate pulsed electromagnetic fields and integrated into clothing |
| AU2020267399A1 (en) | 2019-05-06 | 2021-12-02 | Kamran Ansari | Therapeutic arrays of planar coils configured to generate pulsed electromagnetic fields and integrated into clothing |
| CN111000983A (zh) * | 2019-12-25 | 2020-04-14 | 长春生物制品研究所有限责任公司 | 一种新的重组人白细胞介素-1受体拮抗剂的药用用途 |
| JP7025070B1 (ja) | 2021-05-14 | 2022-02-24 | セルソース株式会社 | 血液由来成長因子含有組成物及びその調製方法 |
| CN113325185B (zh) * | 2021-07-09 | 2024-04-19 | 重庆鼎润医疗器械有限责任公司 | 多水平质控品及其制备方法和在血栓弹力图检测上的应用 |
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| JP5604311B2 (ja) | 2008-03-13 | 2014-10-08 | バイオテスト・アクチエンゲゼルシヤフト | 疾患治療剤 |
| US8518272B2 (en) | 2008-04-04 | 2013-08-27 | Biomet Biologics, Llc | Sterile blood separating system |
| US8182769B2 (en) | 2008-04-04 | 2012-05-22 | Biomet Biologics, Llc | Clean transportation system |
| PL2293816T3 (pl) | 2008-06-06 | 2013-04-30 | Xoma Us Llc | Sposoby leczenia reumatoidalnego zapalenia stawów |
| US9144584B2 (en) | 2008-06-11 | 2015-09-29 | Cell4Vet Corporation | Adipose tissue-derived stem cells for veterinary use |
| US8460227B2 (en) | 2008-11-17 | 2013-06-11 | Arthrex, Inc. | Cytokine concentration system |
| US8177072B2 (en) | 2008-12-04 | 2012-05-15 | Thermogenesis Corp. | Apparatus and method for separating and isolating components of a biological fluid |
| AU2010237191A1 (en) | 2009-04-07 | 2011-11-03 | Velin-Pharma A/S | Method and device for treatment of conditions associated with inflammation or undesirable activation of the immune system |
| WO2010149164A2 (fr) * | 2009-06-22 | 2010-12-29 | Re5 Aps | Appareil et procédé pour traitement par champs électriques pulsés |
| WO2011031553A2 (fr) | 2009-08-27 | 2011-03-17 | Biomet Biologics, Llc | Dispositif implantable pour la production d'antagoniste de récepteur d'interleukine-1 |
| US20110052561A1 (en) | 2009-08-27 | 2011-03-03 | Biomet Biologics,LLC | Osteolysis treatment |
| US20120027746A1 (en) | 2010-07-30 | 2012-02-02 | Biomet Biologics, Llc | Method for generating thrombin |
| EP2611456A2 (fr) | 2010-09-03 | 2013-07-10 | Biomet Biologics, LLC | Méthodes et compositions permettant d'administrer un antagoniste du récepteur de l'interleukine 1 |
-
2011
- 2011-08-24 EP EP11754786.9A patent/EP2611456A2/fr not_active Withdrawn
- 2011-08-24 EP EP15184504.7A patent/EP2977054A1/fr not_active Withdrawn
- 2011-08-24 CA CA2810202A patent/CA2810202C/fr active Active
- 2011-08-24 MX MX2013002488A patent/MX2013002488A/es not_active Application Discontinuation
- 2011-08-24 WO PCT/US2011/048909 patent/WO2012030593A2/fr not_active Ceased
- 2011-08-24 JP JP2013527119A patent/JP2013536841A/ja active Pending
- 2011-08-24 KR KR20137008020A patent/KR20140003398A/ko not_active Withdrawn
- 2011-08-24 AU AU2011296356A patent/AU2011296356B2/en active Active
- 2011-08-24 CN CN2011800457327A patent/CN103249425A/zh active Pending
-
2013
- 2013-03-01 US US13/782,421 patent/US9119829B2/en active Active
-
2015
- 2015-07-20 US US14/803,414 patent/US20160000870A1/en not_active Abandoned
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