JP2008006066A - Device for preparing infusion - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To prepare a large quantity of infusion at once by improving the usability of a device. <P>SOLUTION: The device comprises a first attaching part 10 with a first puncture needle 12 for attaching a vial filled with a medicament, a second attaching part 20 with a second puncture needle 22 for attaching an infusion container filled with lysate, and a third attaching part 30 to which bellows 41 as an air pump is attached. Respective paths 12a and 12b of the first puncture needle 12 are made to communicate with a path 22a of the second puncture needle 22 and the third attaching part 30 independently. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a device for preparing an infusion solution that is used when a drug in a dry preparation in a vial is dissolved in a solution in an infusion container to prepare an appropriate infusion solution.

  A special preparation device has been proposed in order to dissolve a drug in a vial with a dissolution solution and prepare it as an infusion solution such as an instillation (Patent Document 1).

This is configured by integrally forming a vial mounting portion having a puncture needle and a syringe mounting portion for mounting a syringe filled with a solution on both sides of a common disk-shaped hub. Note that the puncture needle of the vial mounting portion has a pair of passages, and one passage passes through the hub and communicates with the syringe mounting portion, and the other passage is open to the outside air through a sterilization filter, for example. It is open. Therefore, this product dissolves the drug in the vial by mounting the vial containing the drug in the vial mounting part, and pushing the syringe mounted in the syringe mounting part to inject the solution in the syringe into the vial. Can be made. When the drug is dissolved in this manner, the syringe is pulled to suck the solution in the vial into the syringe, and the solution is injected into another infusion container and diluted to prepare an appropriate infusion. In addition, since the outside air is introduced into the vial through the sterilization filter when the solution is sucked, there is no possibility that the infusion solution is contaminated.
Japanese Patent Laid-Open No. 7-213585

  When such a conventional technique is used, since the solution sucked into the syringe is reinjected into the infusion container and diluted, the entire operation is complicated, and it is impossible to prepare a large amount of infusion at once. there were. In addition, since the syringe cannot be operated with one hand, there is a problem in that it is not easy to use.

  Therefore, in view of the problems of the prior art, the object of the present invention is to use an air pump that can be operated with one hand, and to install an infusion container containing a dissolving solution, so that it is easy to use and a large amount of infusion can be easily performed at once. An object of the present invention is to provide a device for preparing an infusion that can be prepared.

  In order to achieve this object, the present invention has a first puncture needle having a pair of passages, a first attachment portion for attaching a vial containing a medicine, and a second passage having a single passage. The first puncture needle has a second attachment portion for attaching an infusion container containing a lysing solution and a third attachment portion for attaching an air pump capable of one-hand operation. The gist is to individually communicate with the passage of the second puncture needle and the third attachment portion.

  The first and second mounting portions can be formed on both sides of the intermediate partition wall of the common outer cylinder, and the third mounting portion can be formed on the outer peripheral surface of the outer cylinder.

  The first mounting portion may be arranged with a plurality of guide pieces that guide and keep the mouth of the vial in a circular shape, and the air pump may be a bellows.

  According to the configuration of this invention, each passage of the first puncture needle is individually communicated with the passage of the second puncture needle and the third attachment portion. That is, when the whole infusion container to be attached to the second attachment part is held downward with one hand and the air pump attached to the third attachment part is operated in the pressurizing direction, the air from the air pump is Flows into the vial attached to the first mounting portion through one passage of the puncture needle, and further flows into the infusion container through the other passage of the first puncture needle and the passage of the second puncture needle. To do. Therefore, the inside of the infusion container can be pressurized by the air pressure from the air pump.

  Therefore, when the air pressure of the air pump is removed, the solution in the infusion container is driven by the air pressure in the infusion container and passes through the passage of the second puncture needle and one passage of the first puncture needle. The drug in the vial can be quickly dissolved. After that, when air pressure from the air pump is applied again with the infusion container facing upward, the liquid mixture prepared in the vial returns to the infusion container through the passages of the first puncture needle and the second puncture needle. It is prepared as an appropriate infusion by mixing with the solution in the infusion container. That is, the infusion in the infusion container can be used as it is for drip injection or the like, and a large amount of infusion corresponding to the inner volume of the infusion container can be easily prepared at once. In the above series of operations, the air from the air pump flows into the infusion container through the vial, and returns from the infusion container to the air pump through the vial. There is no risk of contamination of the infusion.

  The first puncture needle is inserted into the rubber stopper at the mouth of the vial by mounting the vial containing the medicine on the first mounting portion. Therefore, one of the passages of the first puncture needle, which is connected to the passage of the second puncture needle, is prepared in the vial by opening it to a low position reaching the inner surface of the rubber stopper. Can be discharged into the infusion container without leaving the entire amount of the mixed liquid. The air pump may be either a bellows type or a plunger type as long as it can be driven in the pressurizing direction by one-hand operation. However, the air pump has a restoring force in the return direction so that the air pressure can be automatically removed by removing the operating force in the pressurizing direction, and may be driven in the return direction via a spring. Good. In addition, the air pump may be integrally assembled in advance with the third mounting portion, and is preferably a disposable type in which the whole including the air pump is discarded for each use.

  The first and second mounting portions formed on both sides of the partition wall of the common outer cylinder are arranged facing each other, the vial is mounted on the first mounting portion, and the infusion container is mounted on the second mounting portion. Even if it is mounted, the whole can be easily held with one hand via the intermediate outer cylinder portion. An air pump that can be operated with one hand is mounted on the third mounting portion formed on the outer peripheral surface of the outer cylinder, but it is preferable that the air pump can be operated as it is with the hand that holds the whole. However, at this time, the first and second puncture needles of the first and second mounting portions are respectively erected in opposite directions on both sides of the partition wall.

  One passage of the first puncture needle penetrates the partition wall and communicates linearly with the passage of the second puncture needle so that the flow of both liquids between the infusion container and the vial is the smoothest. can do. Further, the other passage of the first puncture needle is communicated with the third mounting portion through a passage formed in the radial direction in the partition wall, so that the entire structure is most simply configured, and the whole except the air pump. Can be easily formed integrally. However, the passage of the first puncture needle on the side communicating with the passage of the second puncture needle is preferably arranged on the axis of the outer cylinder together with the passage of the second puncture needle.

  The plurality of guide pieces provided in the first mounting portion guide the mouth portion of the vial and prevent it from being pulled out, so that there is no possibility that the vial is inadvertently detached or tilted due to the elasticity of the rubber stopper of the vial.

  The air pump can be manufactured at the lightest and lowest cost by using a bellows having a restoring force in the direction of removing the air pressure.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings.

  The device for preparing an infusion includes a first mounting portion 10, a second mounting portion 20, and a third mounting portion 30 (FIGS. 1 and 2). However, in FIG. 1 and FIG. 2, a bellows 41 as an air pump attached to the third attachment portion 30 is also illustrated.

  The first and second mounting portions 10 and 20 are formed so as to face each other on both sides of the intermediate partition wall 52 of the common outer cylinder 51. The third mounting portion 30 is formed between the first and second mounting portions 10 and 20 at a right angle to the axis C of the outer cylinder 51 with respect to the outer peripheral surface of the outer cylinder 51. In addition, on the outer periphery of the outer cylinder 51, on the lower side opposite to the third mounting portion 30, anti-slip ribs 51a, 51a,... Slightly shorter than the entire length of the outer cylinder 51 are formed in the axial direction. The circumferential ribs 51b and 51b are formed symmetrically on both sides of the third mounting portion 30 with the axis C1 therebetween (FIGS. 1 and 3).

  The first mounting portion 10 includes half of the outer cylinder 51 terminated by the partition wall 52, and the first puncture needle 12, the guide pieces 13, 13.

  The first puncture needle 12 is arranged eccentric to the axis C of the outer cylinder 51 by a distance δ corresponding to the radius of the first puncture needle 12 on the third mounting portion 30 side. The first puncture needle 12 sharpens the tip and protrudes highly from the tip of the outer cylinder 51 to the outside. The first puncture needle 12 has a pair of passages 12 a and 12 b that open toward the distal end, and the passages 12 a and 12 b are juxtaposed in the direction of the axis C 1 of the third mounting portion 30. However, one passage 12a on the axis C of the outer cylinder 51 passes through the partition wall 52 and opens outside to a position close to the base of the first puncture needle 12 through the axial slit 12c. (FIGS. 1 and 4). The other passage 12 b communicates with the third mounting portion 30 through a passage 53 in the partition wall 52. The passage 53 is formed on the axis C 1 of the third mounting portion 30 in the radial direction of the outer cylinder 51 and the partition wall 52 in the partition wall 52. The first puncture needle 12 is provided with a removable protective cover 12d.

  The guide pieces 13, 13... Are arranged around the first puncture needle 12 in a circle having a smaller diameter than the inner diameter of the outer cylinder 51 (FIGS. 1 and 3). Each guide piece 13 is formed at the same height as the tip of the outer cylinder 51. However, the guide piece 13 on the side forming the third mounting portion 30 is formed integrally with the outer cylinder 51, and the other guide pieces 13, 13... Are formed separately from the inner surface of the outer cylinder 51. . Each guide piece 13 is curved in an arc shape, the tip portion is formed as an inwardly inclined surface, and a hook 13 a that bulges inwardly is formed in the intermediate portion.

  The second mounting portion 20 is equivalent to half of the outer cylinder 51 terminated by the partition wall 52, the center of the partition wall 52, that is, the second puncture needle 22 standing on the axis C of the outer cylinder 51, It has a pair of guide pieces 23 and 23 projecting axially symmetrically at the tip of the outer cylinder 51 (FIGS. 1 and 2).

  The tip of the second puncture needle 22 is higher than the tip of the outer cylinder 51 and is sharply sharpened. The second puncture needle 22 has a passage 22a on the axis C, and the passage 12a of the first puncture needle 12 communicates linearly with the passage 22a. Note that the passage 22 a is opened by branching up and down in the direction of the axis C 1 of the third mounting portion 30 toward the tip of the second puncture needle 22. A cylindrical base 22b is formed at the base of the second puncture needle 22 (FIGS. 1 and 5), and on the second mounting portion 20 side of the partition wall 52, the outer periphery of the base 22b, the outer cylinder 51 A wide rib 52a enclosing the passage 53 and narrow ribs 52b, 52b... Are formed in a cross shape so as to connect the inner circumferences. Note that small axial guide ribs 51c, 51c,... Are formed on the inner periphery of the outer cylinder 51 on the second mounting portion 20 side. The second puncture needle 22 is provided with a removable protective cover 22c.

  The guide pieces 23, 23 are arranged symmetrically in the direction of the axis C1 of the third mounting portion 30 at the tip of the outer cylinder 51, and are each curved in an arc shape. The base portion of each guide piece 23 is bent outward in the radial direction of the outer cylinder 51, and is bent in the axial center C direction so as to protrude in the axial direction of the outer cylinder 51. An inward hook 23 a is formed at the distal end portion of each guide piece 23, and the hook 23 a is formed on an inclined surface toward both the distal end side and the base side of the guide piece 23. Each guide piece 23 is formed to have substantially the same width as the diameter of the third mounting portion 30.

  The third mounting portion 30 is configured by protruding a skirt body 31 on the outer peripheral surface of the outer cylinder 51 (FIGS. 1 and 2). An internal thread 32 is formed on the inner surface of the skirt body 31, and the internal thread 32 is adapted to the external thread 41 a at the mouth of the bellows 41. Further, a seal ring 33 is formed on the top surface of the skirt body 31 so as to enter the mouth of the bellows 41 in an airtight manner, and the passage 53 in the partition wall 52 is the third attachment at the center of the skirt body 31. The portion 30 is smoothly expanded and opened in the direction of the axial center C1. The bellows 41 is airtightly attached to the third attachment portion 30 via a male screw 41a and a female screw 32.

  The entire shape including the first, second, and third mounting portions 10, 20, and 30 other than the bellows 41 is integrally formed of a hard plastic material such as ABS resin. The bellows 41 is formed of, for example, polypropylene or low-density polyethylene. It is assumed that they are integrally formed of a plastic material having an appropriate elasticity. However, the bellows 41 can blow air into the passage 53 by being compressed in the direction of the axis C1, and when the operating force in the direction of the axis C1 is removed, the bellows 41 is elastically restored to its original shape.

  The infusion solution preparation device is used with the bellows 41 mounted on the third mounting portion 30 (FIG. 6). However, the bellows 41 may be prepared by being assembled integrally with the third mounting portion 30 before use. Next, for example, the vial B containing the powdered medicine D is attached to the first attachment portion 10, and the infusion container A containing the solution W is attached to the second attachment portion 20 (in the directions of arrows Kb and Ka in FIG. 6). ).

  In the first mounting portion 10, the protective cover 12d is removed to expose the first puncture needle 12, and the vial B is mounted. At this time, the first puncture needle 12 is inserted into the rubber stopper B1 of the vial B, penetrates the rubber stopper B1, protrudes into the vial B, and opens the passages 12a and 12b into the vial B. The passage 12a on the second mounting portion 20 side opens to the inner surface of the rubber plug B1 through the slit 12c. Further, the mouth portion of the vial B is guided by the guide pieces 13, 13... In the outer cylinder 51, and is elastically prevented from being removed through the hooks 13 a, 13 a.

  The second attachment part 20 is attached with the infusion container A by removing the protective cover 22c to expose the second puncture needle 22. At this time, the second puncture needle 22 is inserted into the rubber stopper A1 of the infusion container A to open the passage 22a into the infusion container A. The guide pieces 23, 23 at the tip of the outer cylinder 51 correctly guide the mouth of the infusion container A onto the axis C to prevent it from being removed.

  Next, the whole is held with one hand so that the infusion container A faces downward and the vial B faces upward (FIG. 7), and the bellows 41 is pushed and shrunk with fingers and operated in the pressurizing direction (arrow K1 in the figure). Direction), the air from the bellows 41 flows into the vial B through the passage 53 and one passage 12b of the first puncture needle 12, and further, the other passage 12a of the first puncture needle 12 and the second passage 12b. Flows into the infusion container A through the passage 22a of the puncture needle 22 and pressurizes the infusion container A. Therefore, if the operating force of the finger on the bellows 41 is removed as it is, the bellows 41 is automatically expanded and restored in the direction of removing the air pressure by the restoring force and the air pressure (in the direction of arrow K2 in FIG. 7).

  At this time, the solution W in the infusion container A is driven in the discharge direction by the air pressure in the infusion container A, and the vial is passed through the passage 22a of the second puncture needle 22 and the passage 12a of the first puncture needle 12. It flows into B and is ejected into the vial B from the passage 12a (arrow K3 in the figure). Therefore, the drug D in the vial B can be quickly dissolved by the jetting solution W and prepared as a mixed solution Wa. In this state, the whole may be shaken up and down (in the direction of the arrow Kc in the same figure) to supplement and accelerate dissolution of the drug D in the vial B.

  Subsequently, when the bellows 41 is pressed again with the vial B facing downward and the infusion container A facing upward (in the direction of the arrow K4 in FIG. 8), the air from the bellows 41 flows into one passage 12b of the first puncture needle 12. Is discharged as a bubble into the mixed solution Wa, flows into the vial B, and the vial B is pressurized. Accordingly, the mixed solution Wa in the vial B returns to the infusion container A via the other passage 12a and the passage 22a of the second puncture needle 22 (arrow K5 in the figure), and the solution W in the infusion container A and By mixing, an appropriate infusion solution Wb can be prepared. However, at this time, it is preferable that the bellows 41 is continuously pressed until the entire amount of the mixed solution Wa in the vial B is discharged or the pressing operation is repeated a plurality of times. The same applies when the mixed solution Wa in the vial B partially flows into the bellows 41. It should be noted that the vial B has a capacity of 10 to 30 ml and the bellows 41 has an effective volume of 15 to 20 ml, and the entire amount of the mixed solution Wa in the vial B can be sufficiently discharged to the infusion container A by a single pushing operation of the bellows 41.

  When the infusion solution Wb is prepared in the infusion container A in this way, the infusion container A is removed from the second mounting part 20, and an infusion device E is connected to the mouth of the infusion container A (FIG. 9). Invert on hook H and hang. That is, the infusion liquid Wb in the infusion container A can be used as it is for drip injection or the like. Further, the device for preparing an infusion after removing the infusion container A removes the empty vial B and discards it.

  In the above description, the bellows 41 is preferably made of a transparent body so that when the mixed solution Wa from the vial B flows into the bellows 41, the discharge of the mixed solution Wa can be confirmed. The bellows 41 can be replaced with any type of air pump including a plunger type or a balloon type such as a nipple for a dropper or a rubber ball of a sphygmomanometer as long as it can be operated with one hand. Further, these air pumps may be mounted on the third mounting portion 30 so as not to be removable.

Overall configuration longitudinal section Overall outline drawing X arrow equivalent view of FIG. Main part enlarged perspective view 1 equivalent view of Y in FIG. Usage state explanatory diagram (1) Usage state diagram (2) Usage state diagram (3) Usage state diagram (4)

Explanation of symbols

B ... Vial D ... Drug A ... Infusion container W ... Dissolved solution 10 ... First attachment part 12 ... First puncture needle 12a, 12b ... Passage 13 ... Guide piece 20 ... Second attachment part 22 ... Second puncture Needle 22a ... passage 30 ... third mounting part 41 ... bellows 51 ... outer cylinder 52 ... partition wall 53 ... passage

Patent applicant Shingo Chemical Co., Ltd.
Attorney Tadaaki Matsuda, Attorney

Claims (5)

  A first puncture needle having a pair of passages, a first attachment portion for attaching a vial containing a medicine, a second puncture needle having a single passage, and an infusion container containing a solution. A second attachment portion to be attached and a third attachment portion to which an air pump capable of one-hand operation is attached. Each passage of the first puncture needle includes a passage of the second puncture needle, 3. A device for preparing an infusion solution, wherein the device is individually communicated with the three mounting portions.   The first and second mounting portions are formed on both sides of an intermediate partition wall of a common outer cylinder, and the third mounting portion is formed on an outer peripheral surface of the outer cylinder. 2. A device for preparing an infusion according to 1.   One passage of the first puncture needle passes through the partition wall and communicates with the passage of the second puncture needle, and the other passage is connected to the third attachment through the passage in the partition wall. The device for preparing an infusion according to claim 2, wherein the device is in communication with a portion.   The infusion solution preparation according to any one of claims 1 to 3, wherein a plurality of guide pieces for guiding and preventing the vial mouth portion from being arranged in a circular manner are arranged in the first mounting portion. device. The infusion preparation device according to any one of claims 1 to 4, wherein the air pump is a bellows.

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