JP2007253131A - Functional water containing anti-oxidant - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide functional water stably containing anti-oxidant. <P>SOLUTION: Conventionally, water is subjected to electrolysis while being passed to obtain alkaline ionized water, after adding ion sources like calcium lactate, for example. However, use of some appropriate pH adjusting agent is needed for using the alkaline ionized water in a neutral state. In the present invention, a non-membrane type electrolysis chamber is provided for preventing alkaline pH value and hydrogen gas obtained by electrolysis is retained, forming a functional water of high dissolved hydrogen concentration. It has physicochemical properties of an oxidation-reduction potential of -200 mV or less, a dissolved oxygen concentration of 0.5 mg/L or more, and a pH value of 6-8, and contains an anti-oxidant. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to functional water containing an antioxidant.

JP-A-2003-175390 discloses functional water in which electrolytic hydrogen is dissolved. This functional water is obtained by adding sodium chloride to pure water and setting the conductivity to 100 μS / cm or more and then electrolyzing it to make the cathode water neutral.
However, since an electrolytic cell equipped with a diaphragm is used for the production of the functional water, the cathode water becomes alkaline and pH adjustment is required. For this reason, it takes time and effort to prepare and add sodium phosphate and the like. Moreover, it is not preferable to use anodic water for pH adjustment because active oxygen in the anodic water is added.
For this reason, the present inventors have developed a hydrogen water generator disclosed in Japanese Patent Application Laid-Open No. 2005-186034. This device prepares functional water by performing electrolysis in a non-membrane state between the anode and the cathode, storing the generated hydrogen gas, and dissolving the hydrogen gas in water at a high concentration. It is.

JP 2003-175390 A Japanese Patent Laid-Open No. 2005-186034

However, the functional water that the inventors have successfully developed has not been sufficiently known for its properties and uses.
This invention is made | formed in view of an above-described situation, The objective is to provide the functional water which contains an antioxidant stably.

In general, antioxidants typified by vitamin C are very unstable in the high pH range, and when antioxidants are dissolved in conventional alkaline ionized water, the antioxidants are decomposed after several hours to several tens of hours. For this reason, it has been difficult to sufficiently exert the effect of the antioxidant. However, according to the study by the present inventors, it has been found that by using water produced by a specific production method, such an unstable antioxidant can be stably maintained over a long period of time. The present invention has been completed.
In order to solve the above-mentioned problem, the functional water according to the first invention is neutral water having a pH of 6 to 8 (hereinafter, functional water in a neutral region of pH 6 to 8 is referred to as “neutral water”). The hydrogen gas generated by electrolyzing the neutral water, and storing the hydrogen gas in a high concentration by storing the hydrogen gas and dissolving it in the neutral water. The chemical characteristics are characterized in that the oxidation-reduction potential is −200 mV or less, the dissolved hydrogen concentration is 0.5 mg / L or more, and an antioxidant is contained.

  In the above invention, the antioxidant is vitamin C, vitamin E, vitamin A, catechins, coenzyme Q10, flavonoids, anthocyanins, proanthocyanidins, silymarin, hesperidin, rutin, alpha lipoic acid, flavangenol, SOD, alpha carotene , Beta carotene, selenium, manganese, zinc, cysteine, glutathione, melatonin, enzogenol, pycnogenol, lycopene, lutein.

In the apparatus for producing functional water according to the present invention, since a method of storing electrolytic gas is used, the active oxygen generated on the anode side is self-dissipated to return to oxygen, or removed by a subsequent activated carbon filter. Thus, active oxygen is prevented from being contained in the functional water.
As for the use of the functional water of the present invention, it can be taken into the body using methods such as oral, injection, infusion, and rectal.

Of these, oral intake is most preferred. In this case, drink functional water of 20 ml / kg (body weight) to 70 ml / kg (body weight) (preferably 40 ml / kg (body weight) to 50 ml / kg (body weight)) per day. Ingest by. In addition, when drinking functional water as it is, it can be used, for example, as cooking water. Functional water can be taken in several divided doses per day.
When oral intake of functional water is difficult, functional water can be used as an infusion solution itself or as water for preparing various pharmaceuticals. In this case, 5 ml / kg (body weight) to 70 ml / kg (body weight) (preferably 15 ml / kg (body weight) to 30 ml / kg (body weight)) of functional water is infused per day. be able to.

  According to the present invention, there is provided a novel functional water that exhibits a high dissolved hydrogen concentration and a low redox potential, has a high active oxygen removal capability, and generally has an activity of efficiently retaining an antioxidant that is easily decomposed. Is done.

  Next, embodiments of the present invention will be described with reference to the drawings. However, the technical scope of the present invention is not limited by these embodiments, and various forms are possible without changing the gist of the invention. Can be implemented. Further, the technical scope of the present invention extends to an equivalent range.

<Physicochemical properties of functional water>
The functional water was prepared by an apparatus prepared using the technique disclosed in Japanese Patent Application Laid-Open No. 2005-186034. The characteristics of this apparatus and functional water were confirmed as follows.
1. Measurement of dissolved hydrogen concentration and oxidation-reduction potential of prepared functional water Functional water was prepared under conditions of electrolysis of 200 mA × 6 hours, electrolysis pressure of 0.04 MPa, feed water pressure of 0.18 MPa, and water temperature of 27 ° C. Functional water was passed from this device at a rate of water volume of 3.5 L / min and space velocity (SV) of 140 hr ⁻¹ , dissolved hydrogen / dissolved oxygen (mg / L) and redox potential ( mV) was measured.
The results are shown in FIG. The pH of the functional water at this time was almost neutral at 6.6.

2. Measurement of dissolved hydrogen concentration in functional water left in the apparatus after preparation After the functional water was prepared under the same conditions as described above, it was placed in the apparatus at 14 ° C or 16 ° C for 0.5 to 60 hours. The dissolved hydrogen concentration in the water was measured when water was passed through the device storing the left functional water.
The results are shown in FIG.

Further, FIG. 3 shows the relationship between the dissolved hydrogen amount when the water flow rate is 2.2 L (corresponding to the dissolved hydrogen amount at the peak in FIG. 2) and the standing time.
In the functional water manufacturing apparatus used for this embodiment, it manufactures in the form which stores electrolytic hydrogen. For this reason, when water begins to flow through the apparatus, the dissolved hydrogen concentration in the water decreases with time, and the oxidation-reduction potential and the dissolved oxygen concentration increase.

In general, when tap water is used for eating and drinking at home, the water flow treatment is completed in about 1 minute (about 2 to 3 L as capacity) from the start of water flow. For this reason, if an amount of about 3 L flows (position of about 0.8 min in FIG. 1), if sufficient dissolved hydrogen concentration and oxidation-reduction potential are maintained, the functional water has sufficient effect. It remains in the state prepared for.
According to FIGS. 1 to 3, the dissolved hydrogen concentration of the functional water was at most 0.8 mg / L or more under such general use conditions. Moreover, the oxidation-reduction potential at this time was lower than -200 mV.

<Functional water active oxygen removal ability confirmation test>
Next, the active oxygen removal ability was compared for pure water, alkaline ionized water, and functional water of this embodiment.
As alkaline ionized water, two types of alkaline ionized water adjusters with different manufacturers who received medical approval were selected, and those manufactured by the water conditioner were used. These alkaline ionized waters are produced by a conventional method in which an ion source such as calcium lactate is added to water for electrolysis.
As the functional water, one having a dissolved hydrogen concentration of 0.8 mg / L or more, an oxidation-reduction potential of −200 mV or less, and a pH of about 7 was used.

Hydrogen peroxide was added as an active oxygen source to the above three types of water, and the remaining hydroxy radicals were measured by ESR.
The results are shown in FIG. In addition, since almost the same result was obtained with two types of alkaline ionized water, a representative graph is shown in FIG.
From the figure, when the peak value (R) corresponding to the hydroxy radical concentration is relatively compared, it was 48% for alkaline ionized water and 32% for functional water compared to 100% for pure water. From this, it was shown that the functional water of this embodiment has stronger antioxidant power than the alkali ion water obtained by the conventional method.

<Vitamin C retention effect confirmation test>
Next, the effect of retaining vitamin C was compared between alkaline ionized water and functional water.
As alkaline ionized water, two types of alkaline ionized water purifiers with different manufacturers who received medical approval were selected, and those prepared by the water purifier were used.
Further, as the functional water, an initial water quality having a dissolved hydrogen concentration of 0.8 mg / L and an oxidation-reduction potential of −200 mV was used, and ascorbic acid was dissolved as a vitamin C source in the functional water. The dissolved hydrogen concentration in the solution at the start of the test was 0.5 mg / L, and the oxidation-reduction potential was -200 mV.
The initial concentration of ascorbic acid was diluted with alkaline ionized water or functional water so as to be 80 μM. This solution was dispensed into a vial in an appropriate amount and then put into a 37 ° C. incubator. At 6 and 30 hours after addition, the vials were removed from the incubator and 50 μM dithiothreitol was added to prevent vitamin C oxidation and stored at 4 ° C.

After all the reactions were completed, the vitamin C concentration in each sample solution was measured by HPLC. As the mobile phase for HPCL measurements, using _{0.1M KH 2 PO 4 -H 3 PO} 4 + 0.1mM EDTA-2Na.
The results are shown in FIG. From the figure, it was found that in alkaline ionized water, the residual rate was 38% after 6 hours and 14% after 30 hours, indicating that vitamin C was rapidly decomposed. On the other hand, functional water showed a very good residual rate of 96% after 6 hours and 67% after 30 hours. From this, it was found that functional water exhibits a very high vitamin C retention effect as compared with alkaline ionized water.

  Thus, according to this embodiment, by adding an antioxidant to functional water having a high dissolved hydrogen concentration of 0.5 mg / L or higher, a redox potential of −200 mV or lower, and a pH of 6 to 8, It was found that the antioxidant can be retained stably over a long period of time. Such an antioxidant-containing functional water can effectively be used as water for maintaining health because it has an action of preventing oxidation of the human body.

It is a graph which shows the characteristic of the functional water manufactured with the manufacturing apparatus. It is a graph which shows the relationship between the amount of water flow and dissolved hydrogen concentration when functional water manufactured with the manufacturing apparatus is allowed to flow after being left for 0.5 to 60 hours. In FIG. 2, it is a graph which shows the relationship between standing time and the amount of dissolved hydrogen when water flow volume is 2.2L. It is a chart figure which shows a result when the hydroxy radical which remains in each solution is measured by ESR. The results of (A) pure water, (B) alkali ion water, and (C) functional water are respectively shown. It is a graph which shows the amount of vitamin C remaining in each solution. The results of (A) functional water and (B) alkali ion water are respectively shown.

Claims (2)

Neutral water with a pH of 6 to 8 and hydrogen gas generated by electrolyzing the neutral water are stored and dissolved in the neutral water. The physicochemical characteristics are functional water having an oxidation-reduction potential of −200 mV or less, a dissolved hydrogen concentration of 0.5 mg / L or more, and containing an antioxidant. The antioxidants include vitamin C, vitamin E, vitamin A, catechins, coenzyme Q10, flavonoids, anthocyanins, proanthocyanidins, silymarin, hesperidin, rutin, alpha lipoic acid, flavangenol, SOD, alpha carotene, beta carotene, The functional water according to claim 1, comprising one or more substances selected from selenium, manganese, zinc, cysteine, glutathione, melatonin, enzodinol, pycnogenol, lycopene, and lutein.

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