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JP2006325704A - Ultrasonic diagnostic equipment - Google Patents

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JP2006325704A
JP2006325704A JP2005150478A JP2005150478A JP2006325704A JP 2006325704 A JP2006325704 A JP 2006325704A JP 2005150478 A JP2005150478 A JP 2005150478A JP 2005150478 A JP2005150478 A JP 2005150478A JP 2006325704 A JP2006325704 A JP 2006325704A
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measurement point
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movement amount
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Takao Suzuki
隆夫 鈴木
Takashi Hagiwara
尚 萩原
Makoto Kato
真 加藤
Yoshinao Sorinaka
由直 反中
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Panasonic Holdings Corp
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Matsushita Electric Industrial Co Ltd
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Abstract

【課題】 被検体組織の2次元の動きを精度よく追跡することができる超音波診断装置を提供する。
【解決手段】 超音波診断装置hが、被検体内に設定された計測点に対して少なくとも2つの異なる偏向角をもって超音波を送受信する探触子101,送信部102,受信部103と、各々の超音波送受信方向に沿った計測点の移動量を求める移動量演算部111と、異なる偏向角をもって送受信した超音波送受信方向に沿った少なくとも2つの移動量から計測点の2次元又は3次元の移動量を求めるとともに、計測点の2次元又は3次元の移動量を計測点の移動前の位置に加えて計測点の2次元又は3次元の動きを追跡する位置追跡部113を有する。
【選択図】図1
PROBLEM TO BE SOLVED: To provide an ultrasonic diagnostic apparatus capable of accurately tracking a two-dimensional movement of a subject tissue.
An ultrasound diagnostic apparatus h includes a probe 101, a transmission unit 102, and a reception unit 103 that transmit and receive ultrasonic waves with at least two different deflection angles with respect to a measurement point set in a subject. The movement amount calculation unit 111 for obtaining the movement amount of the measurement point along the ultrasonic transmission / reception direction and the two-dimensional or three-dimensional measurement point from at least two movement amounts along the ultrasonic transmission / reception direction transmitted / received with different deflection angles. A position tracking unit 113 that obtains the movement amount and adds the two-dimensional or three-dimensional movement amount of the measurement point to the position before the measurement point is moved to track the two-dimensional or three-dimensional movement of the measurement point.
[Selection] Figure 1

Description

本発明は、被検体組織の動きを追跡する超音波診断装置、及び、追跡波形から組織性状を求める超音波診断装置に関する。   The present invention relates to an ultrasonic diagnostic apparatus that tracks the movement of a subject tissue and an ultrasonic diagnostic apparatus that obtains a tissue property from a tracking waveform.

超音波診断装置は、超音波を被検体に発信すると共に被検体の組織で反射された超音波(反射エコー信号)を受信し、この受信した超音波の強度を輝度に変換することで、被検体の断層画像を得るものである。また、超音波診断装置の一形態として、反射エコー信号の位相を解析することにより被検体組織の動きを精密に測定し、その測定結果をもとに被検体組織の歪み、弾性率や粘性率などの組織性状を求める試みが為されている。   The ultrasonic diagnostic apparatus transmits an ultrasonic wave to a subject and receives an ultrasonic wave (reflected echo signal) reflected by the tissue of the subject, and converts the intensity of the received ultrasonic wave into a luminance. A tomographic image of the specimen is obtained. As one form of ultrasonic diagnostic equipment, the motion of the subject tissue is accurately measured by analyzing the phase of the reflected echo signal, and the distortion, elastic modulus and viscosity of the subject tissue are based on the measurement result. Attempts have been made to determine the tissue properties.

例えば、特許文献1には、反射エコー信号を検波して得られた出力信号の振幅と位相を用いて、被検体の瞬間的な位置を決定することによって被検体組織の追跡を高精度に行ない、拍動による大振幅変位運動に重畳している微小振動を捕らえる方法が記載されている。   For example, in Patent Document 1, the tissue of a subject is tracked with high accuracy by determining the instantaneous position of the subject using the amplitude and phase of an output signal obtained by detecting a reflected echo signal. A method for capturing minute vibrations superimposed on large-amplitude displacement motion due to pulsation is described.

図12を用いて、特許文献1に開示された被検体組織追跡方法を説明する。被検体の同一方向に対して、時刻t=0に送信された超音波パルスの受信エコー信号をy(t)、時刻t=ΔTに送信された超音波パルスのエコー信号をy(t+ΔT)とする。また、ある位置(深度)xにある計測点から反射されたエコーの受信時刻txは、パルス送信時刻をt=0とすると、tx=x/(C/2)〔C:被検体内を伝播する超音波の速度〕で与えられる。次に、受信エコー信号y(tx)とy(tx+ΔT)の位相差をΔθ、受信時刻tx付近における超音波の中心周波数をfとすると、この時間ΔT内の計測点の移動量Δxは次の式(1)で与えられる。

Figure 2006325704
従って、ΔT後の物体Aの位置x’は次の式(2)で与えられる。
Figure 2006325704
The subject tissue tracking method disclosed in Patent Document 1 will be described with reference to FIG. For the same direction of the subject, the received echo signal of the ultrasonic pulse transmitted at time t = 0 is y (t), and the echo signal of the ultrasonic pulse transmitted at time t = ΔT is y (t + ΔT). To do. In addition, the reception time tx of the echo reflected from the measurement point at a certain position (depth) x is tx = x / (C / 2) [C: propagation in the subject, where t = 0 is the pulse transmission time. The speed of the ultrasound to be given]. Next, if the phase difference between the received echo signals y (tx) and y (tx + ΔT) is Δθ, and the center frequency of the ultrasonic wave near the reception time tx is f, the movement amount Δx of the measurement point within this time ΔT is It is given by equation (1).
Figure 2006325704
Therefore, the position x ′ of the object A after ΔT is given by the following equation (2).
Figure 2006325704

この計算を繰り返すことで、被検体内の特定の計測点の位置を追跡できる。つまり、位置(深度)x’から反射されたエコーの受信時刻をtx’とすると、受信エコー信号y(tx’+ΔT)とy(tx’+2ΔT)の位相差をもとに、式(1)と式(2)から2ΔT後の計測点の位置x”を求めることができる。   By repeating this calculation, the position of a specific measurement point in the subject can be tracked. That is, assuming that the reception time of the echo reflected from the position (depth) x ′ is tx ′, the expression (1) is obtained based on the phase difference between the reception echo signals y (tx ′ + ΔT) and y (tx ′ + 2ΔT). And the position x ″ of the measurement point after 2ΔT can be obtained from the equation (2).

特許文献2には、特許文献1の方法をさらに発展させ、心拍による血管壁の内面および外面の各大振幅変位運動を精密に追跡し、大振幅変位運動に重畳されている微小振動の運動速度を求め、その差から血管壁の歪み量を計測し、歪み量と血圧差から局所弾性率を求める方法および、弾性率の空間分布を画像表示する装置が記載されている。   In Patent Document 2, the method of Patent Document 1 is further developed to accurately track the large amplitude displacement motions of the inner and outer surfaces of the blood vessel wall due to the heartbeat, and the motion speed of micro vibrations superimposed on the large amplitude displacement motions. And a method of measuring the strain amount of the blood vessel wall from the difference, obtaining the local elastic modulus from the strain amount and the blood pressure difference, and an apparatus for displaying an image of the spatial distribution of the elastic modulus.

図13を参照して、特許文献2に開示された弾性率算出方法を説明する。同文献によれば、探触子101は被検体に対して超音波を照射し、血管、特に動脈からのエコーを受信する。血管壁に測定点A,B(血管の中心軸を含む横断面上にあって該中心軸から径方向に異なる距離を有する2点)を設定し、測定点A,Bからの受信信号を特許文献1に示された方法で解析し、測定点A,Bの動きを追跡する。ここで、動脈は心拍によって収縮拡張を繰り返しており、心臓収縮期には血管自体は膨張すると共に、急激に血管壁の厚みが減少し、心臓拡張期には血管自体は収縮すると共に、ゆっくりと血管壁の厚みが増加する。そのため、測定点A,Bは、追跡波形TA,TBで示す周期的な挙動を示し、これらの追跡波形TA,TBの差から測定点A−B間の厚み(距離)変化波形Wが求まる。   The elastic modulus calculation method disclosed in Patent Document 2 will be described with reference to FIG. According to this document, the probe 101 irradiates a subject with ultrasonic waves and receives echoes from blood vessels, particularly arteries. Measurement points A and B (two points on the cross section including the central axis of the blood vessel and having different distances in the radial direction from the central axis) are set on the blood vessel wall, and the received signals from the measurement points A and B are patented. Analysis is performed by the method shown in Document 1, and the movement of the measurement points A and B is tracked. Here, the artery repeatedly contracts and dilates due to the heartbeat, and during the systole, the blood vessel itself expands and the thickness of the blood vessel wall decreases rapidly, and during the diastole, the blood vessel itself contracts and slowly The thickness of the vessel wall increases. Therefore, the measurement points A and B exhibit a periodic behavior indicated by the tracking waveforms TA and TB, and a thickness (distance) change waveform W between the measurement points A and B is obtained from the difference between the tracking waveforms TA and TB.

したがって、厚み変化波形Wの変化量をΔW、測定点初期化時の基準厚みをWsとすると、測定点A−B間の歪み量εは式(3)で与えられる。

Figure 2006325704
Therefore, assuming that the change amount of the thickness change waveform W is ΔW and the reference thickness at the time of measurement point initialization is Ws, the strain amount ε between the measurement points A and B is given by Expression (3).
Figure 2006325704

この歪み量εが血管壁にかかる血圧差ΔPによりもたらされたものとすると、測定点A−B間の弾性率Erは式(4)で与えられる。

Figure 2006325704
そして、以上の計算を断層画像上の複数点に対して行なうことで、弾性率の分布画像が得られる。
特開平10−5226号公報 特開2000−229078号公報 Assuming that this strain amount ε is caused by the blood pressure difference ΔP applied to the blood vessel wall, the elastic modulus Er between the measurement points A and B is given by the equation (4).
Figure 2006325704
The elastic modulus distribution image is obtained by performing the above calculation on a plurality of points on the tomographic image.
Japanese Patent Laid-Open No. 10-5226 JP 2000-229078 A

しかしながら、被検体組織は深さ方向だけでなく、横方向の動きを伴うものであるが、上述の公報に記載の組織追跡方法では、超音波の進行方向、つまり深さ方向の動きしか追跡できないという問題があった。そこで、本発明は、上述の組織追跡方法を改良したものであり、被検体組織の2次元の動きを精度よく追跡することができる超音波診断装置を提供することを目的とする。また、2次元の動きを精度よく追跡することにより、歪みや弾性率、粘性率などの組織性状を精度よく求めることができる超音波診断装置を提供することを目的とする。   However, although the subject tissue is accompanied not only by the depth direction but also by the lateral movement, the tissue tracking method described in the above publication can track only the ultrasonic traveling direction, that is, the depth direction movement. There was a problem. Therefore, the present invention is an improvement of the above-described tissue tracking method, and an object thereof is to provide an ultrasonic diagnostic apparatus capable of accurately tracking a two-dimensional movement of a subject tissue. It is another object of the present invention to provide an ultrasonic diagnostic apparatus that can accurately determine tissue properties such as strain, elastic modulus, and viscosity by tracking two-dimensional movement with high accuracy.

この目的を達成するために、本発明に係る超音波診断装置は、
被検体内に設定された計測点に対して少なくとも2つの異なる偏向角をもって超音波を送受信する手段と、
各々の超音波送受信方向に沿った計測点の移動量を求める手段と、
異なる偏向角をもって送受信した超音波送受信方向に沿った少なくとも2つの移動量から上記計測点の2次元又は3次元の移動量を求める手段と、
上記計測点の2次元又は3次元の移動量を上記計測点の移動前の位置に加えて上記計測点の2次元又は3次元の動きを追跡する手段を備えたことを特徴とする。
In order to achieve this object, an ultrasonic diagnostic apparatus according to the present invention includes:
Means for transmitting and receiving ultrasound with at least two different deflection angles with respect to a measurement point set in the subject;
Means for determining the amount of movement of the measurement point along each ultrasonic transmission / reception direction;
Means for obtaining a two-dimensional or three-dimensional movement amount of the measurement point from at least two movement amounts along the ultrasonic transmission / reception direction transmitted / received with different deflection angles;
A means for tracking the two-dimensional or three-dimensional movement of the measurement point by adding the two-dimensional or three-dimensional movement amount of the measurement point to the position before the measurement point is moved is provided.

本発明に係る超音波診断装置の他の形態は、
異なる偏向角を与えた少なくとも2つの超音波のそれぞれによって被検体を断面又はボリュームを走査する手段と、
上記被検体内に2次元又は3次元に設定された複数の計測点のそれぞれの超音波送受信方向の移動量を求める手段と、
上記複数の計測点のそれぞれについて、異なる偏向角を有する超音波送受信方向に沿った少なくとも2つの移動量から計測点の2次元又は3次元の移動量を求める手段と、
上記複数の計測点のそれぞれについて、上記2次元又は3次元の移動量を計測点の移動前の位置に加えて2次元又は3次元の動きを追跡する手段を備えたことを特徴とする。
Another form of the ultrasonic diagnostic apparatus according to the present invention is as follows:
Means for scanning a cross-section or volume of the subject by each of at least two ultrasound waves provided with different deflection angles;
Means for obtaining a movement amount in the ultrasonic transmission / reception direction of each of a plurality of measurement points set in a two-dimensional or three-dimensional manner in the subject;
Means for obtaining a two-dimensional or three-dimensional movement amount of the measurement point from at least two movement amounts along the ultrasonic transmission / reception direction having different deflection angles for each of the plurality of measurement points;
For each of the plurality of measurement points, means for tracking the two-dimensional or three-dimensional movement by adding the two-dimensional or three-dimensional movement amount to the position before the measurement point is moved is provided.

これら超音波診断装置は、上記超音波送受信方向に沿った計測点の移動量、又は上記計測点の2次元又は3次元の移動量、若しくはそれらの両方を記憶する手段を有することが好ましい。   These ultrasonic diagnostic apparatuses preferably have means for storing the movement amount of the measurement point along the ultrasonic transmission / reception direction, the two-dimensional or three-dimensional movement amount of the measurement point, or both.

また、上記2つの超音波送受信方向に沿った計測点の移動量を求める手段は、それぞれの超音波送受信方向について計測点の移動量を複数回求めると共にこれら複数回求めた移動量を補間して、上記2つの超音波送受信方向に沿った計測点の移動量を時間差無く求めることが好ましい。   Further, the means for obtaining the movement amount of the measurement point along the two ultrasonic transmission / reception directions obtains the movement amount of the measurement point for each ultrasonic transmission / reception direction a plurality of times and interpolates the movement amounts obtained for the plurality of times. It is preferable to obtain the amount of movement of the measurement points along the two ultrasonic transmission / reception directions without a time difference.

さらに、超音波診断装置は、上記検出した2次元的または3次元的な動きを追跡した結果から被検体の組織性状を表す値を算出する手段をさらに有し、上記組織性状を表す値は、少なくとも被検体組織の厚み変化量、速度、歪み、弾性率、粘性率のいずれかであることが好ましい。   Further, the ultrasonic diagnostic apparatus further includes means for calculating a value representing the tissue property of the subject from the result of tracking the detected two-dimensional or three-dimensional movement, and the value representing the tissue property is: It is preferably at least one of the thickness change amount, speed, strain, elastic modulus, and viscosity of the subject tissue.

さらにまた、上記2次元または3次元の動きを追跡した後は、被計測組織の動きと平行な方向に偏向させた超音波をもって被計測組織の動きを追跡することが好ましい。   Furthermore, after tracking the two-dimensional or three-dimensional movement, it is preferable to track the movement of the measured tissue with ultrasonic waves deflected in a direction parallel to the movement of the measured tissue.

そして、上記2次元または3次元の動きの追跡は、超音波送受信中定期的に行なうことを特徴とする請求項6記載の超音波診断装置。   The ultrasonic diagnostic apparatus according to claim 6, wherein the tracking of the two-dimensional or three-dimensional movement is periodically performed during ultrasonic transmission / reception.

そしてまた、上記2次元または3次元の動きの追跡は、超音波送受信停止時から超音波送受信を開始した直後に行なうことが好ましい。   The tracking of the two-dimensional or three-dimensional movement is preferably performed immediately after the ultrasonic transmission / reception is started after the ultrasonic transmission / reception is stopped.

本発明によれば、被検体組織の2次元又は3次元の動きをより正確に追跡することができる。また、被検体組織の2次元又は3次元の動きを精度よく追跡することにより、被検体組織の歪みや弾性率、粘性率などの組織性状を精度よく求めることができる。   According to the present invention, two-dimensional or three-dimensional movement of a subject tissue can be tracked more accurately. Further, by accurately tracking the two-dimensional or three-dimensional movement of the subject tissue, the tissue properties such as strain, elastic modulus, and viscosity of the subject tissue can be obtained with high accuracy.

以下、本発明の実施の形態について、図を用いて説明する。なお、以下の説明では、必要に応じて特定の方向や場所を示す用語(「上」、「下」、「右」、「左」及びそれらの派生語)を使用するが、これらの用語を使用するのは発明の理解を容易にするためであり、発明の技術的範囲を解釈するために利用されるべきものではない。   Hereinafter, embodiments of the present invention will be described with reference to the drawings. In the following explanation, terms ("up", "down", "right", "left" and their derivatives) indicating specific directions and places are used as necessary. It is used to facilitate understanding of the invention and should not be used to interpret the technical scope of the invention.

〔超音波診断装置の構成及び動作〕
図1は、超音波診断装置の機能構成を示すブロック図である。図示するように、超音波診断装置は、制御手段として制御部100を有する。図面上、制御部100は、以下に説明する他の機能部から独立した状態で表示されているが、これら機能部と相互に関連付けられている。図示していないが、キーボードやトラックボール、スイッチ、ボタンといったユーザーインターフェース(入力手段)が制御部100に接続されており、これらのユーザーインターフェイスを操作することにより制御部に必要な情報が入力される。被検体(図示しないが、通常は人である。)に当接して使用される探触子101は送信部102と受信部103に接続されている。送信部102は、制御部100から超音波発信指令を受信すると、指定されたタイミングで探触子101を駆動する信号を発生して探触子101に送信する。探触子101は、送信部102から出力された信号に基づいて超音波を発信し、被検体に照射する。また、探触子101は、被検体内部から反射してきた超音波エコーを電気信号に変換する。
[Configuration and operation of ultrasonic diagnostic equipment]
FIG. 1 is a block diagram showing a functional configuration of the ultrasonic diagnostic apparatus. As shown in the figure, the ultrasonic diagnostic apparatus includes a control unit 100 as control means. In the drawing, the control unit 100 is displayed in a state independent of other functional units described below, but is associated with these functional units. Although not shown, a user interface (input means) such as a keyboard, a trackball, a switch, and a button is connected to the control unit 100, and necessary information is input to the control unit by operating these user interfaces. . A probe 101 that is used in contact with a subject (not shown but is usually a person) is connected to a transmitter 102 and a receiver 103. When receiving an ultrasonic wave transmission command from the control unit 100, the transmission unit 102 generates a signal for driving the probe 101 at a designated timing and transmits the signal to the probe 101. The probe 101 emits an ultrasonic wave based on the signal output from the transmission unit 102 and irradiates the subject. The probe 101 converts an ultrasonic echo reflected from the inside of the subject into an electric signal.

図示しないが、探触子101内には超音波と電気信号を相互に変換する複数の圧電変換素子が1次元又は2次元に配置されており、これらの圧電変換素子を選択し、また圧電変換素子に電圧与えるタイミングを調整し、送受信する超音波の偏向角およびフォーカスを制御する。   Although not shown in the drawing, a plurality of piezoelectric transducers that mutually convert ultrasonic waves and electrical signals are arranged in one or two dimensions in the probe 101, and these piezoelectric transducers are selected and piezoelectric transducers are selected. The timing of applying a voltage to the element is adjusted, and the deflection angle and focus of the ultrasonic wave to be transmitted and received are controlled.

受信部103は、探触子101から出力された受信信号を増幅するとともに、定められた位置(フォーカス)または方向(偏向角)からの超音波のみを検出する。   The receiving unit 103 amplifies the reception signal output from the probe 101 and detects only ultrasonic waves from a predetermined position (focus) or direction (deflection angle).

断層画像処理部104は、フィルタ、検波器、対数増幅器などからなり、受信信号の主に振幅を解析して、被検体の内部構造を画像化する。画像化された画像データは、画像合成部106に送信される。   The tomographic image processing unit 104 includes a filter, a detector, a logarithmic amplifier, and the like, and mainly analyzes the amplitude of the received signal to image the internal structure of the subject. The imaged image data is transmitted to the image composition unit 106.

組織追跡部105は、受信部103から出力された受信信号を記憶する記憶部110と、受信信号間の位相差から上述の式1に基づいて音響走査線に沿う被検体組織の移動量を求める移動量演算部111と、移動量演算部111で演算された被検体組織の移動量を記憶する記憶部112と、上述の式2を拡張し、異なる偏向角をもって探触子101から発振された2つの超音波から得られた2つの方向の移動量をベクトル合成して被検体組織の移動量と移動後の位置を求めることで被検体組織の2次元又は3次元の動きを追跡する位置追跡部113を有する。組織追跡部105における処理については後に詳述する。   The tissue tracking unit 105 calculates the amount of movement of the subject tissue along the acoustic scanning line from the storage unit 110 that stores the reception signal output from the reception unit 103 and the phase difference between the reception signals based on the above-described Equation 1. The movement amount calculation unit 111, the storage unit 112 that stores the movement amount of the subject tissue calculated by the movement amount calculation unit 111, and the above Equation 2 are expanded and oscillated from the probe 101 with different deflection angles. Position tracking that tracks the two-dimensional or three-dimensional movement of the subject tissue by calculating the amount of movement of the subject tissue and the post-movement position by vector synthesis of the movement amounts in two directions obtained from two ultrasonic waves Part 113. The processing in the tissue tracking unit 105 will be described in detail later.

組織性状演算部108は、組織追跡部105が追跡した被検体組織の動きから、被検体組織の組織性状を表すパラメータ、例えば上述の式3で与えられる歪み量、また、上述の式4で与えられる弾性率などを算出する。組織性状を表すパラメータは、数値データ、または値を色データに変換して2次元座標に展開した2次元分布画像データに変換され、画像合成部106に送信される。   From the movement of the subject tissue tracked by the tissue tracking unit 105, the tissue property calculation unit 108 gives a parameter representing the tissue property of the subject tissue, for example, the distortion amount given by the above-described equation 3 or given by the above-described equation 4. Calculate the elastic modulus. The parameter representing the tissue property is converted into numerical data or two-dimensional distribution image data in which the value is converted into color data and developed into two-dimensional coordinates, and transmitted to the image composition unit 106.

画像合成部106は、組織性状演算部108から出力された弾性率などの組織性状を表すパラメータの数値データ又は画像データと、断層画像処理部104から出力された弾性画像を合成し、その合成画像を画像表示部107に出力して表示する。   The image synthesizing unit 106 synthesizes numerical data or image data of parameters representing tissue properties such as elastic modulus output from the tissue property calculating unit 108 and the elastic image output from the tomographic image processing unit 104, and the combined image Is output to the image display unit 107 and displayed.

〔組織追跡部の処理〕
図2と図3を参照して、被検体内の組織追跡処理を説明する。
[Processing of organization tracking part]
With reference to FIGS. 2 and 3, the tissue tracking process in the subject will be described.

〔ステップ1〕:探触子101は、制御部100からの指令に基づいて動作し、被検体中の位置Xにある計測点に対し、図3の右上から左下に向けて第1の偏向角θaをもって偏向した音響走査線aに沿って超音波を被検体に送信し、その反射エコーを受信する。受信した反射エコーは電気信号(1回目の受信信号)に変換される。変換された電気信号は記憶部110に記憶される。 [Step 1]: The probe 101 operates based on a command from the control unit 100, and the first deflection angle from the upper right to the lower left in FIG. 3 with respect to the measurement point at the position X in the subject. Ultrasound is transmitted to the subject along the acoustic scanning line a deflected with θa, and the reflected echo is received. The received reflected echo is converted into an electric signal (first received signal). The converted electrical signal is stored in the storage unit 110.

〔ステップ2〕:探触子101は、制御部100からの指令に基づいて再び動作し、再度音響走査線aに沿って超音波を被検体に送信する。受信された反射エコーは電気信号(2回目の受信信号)に変換される。変換された電気信号は、記憶部110に記憶される。 [Step 2]: The probe 101 operates again based on a command from the control unit 100, and again transmits ultrasonic waves along the acoustic scanning line a to the subject. The received reflected echo is converted into an electrical signal (second received signal). The converted electrical signal is stored in the storage unit 110.

〔ステップ3〕:移動量演算部111は、記憶部110から1回目と2回目の受信信号を取得し、これら2つの受信信号の位相差から、上述の式1に基づいて、音響走査線aに沿った方向(第1の偏向方向)に関する位置Xの移動量(ベクトル量)ΔX(a)を計算する。計算された移動量ΔX(a)は、記憶部112と位置追跡部113に送信される。 [Step 3]: The movement amount calculation unit 111 acquires the first and second reception signals from the storage unit 110, and based on the above-described Expression 1 from the phase difference between the two reception signals, the acoustic scanning line a The movement amount (vector amount) ΔX (a) of the position X with respect to the direction along the first direction (first deflection direction) is calculated. The calculated movement amount ΔX (a) is transmitted to the storage unit 112 and the position tracking unit 113.

〔ステップ4,5〕:制御部100からの指令に基づいて、探触子101は、被検体中の位置Xにある計測点に対し、図3の左上から右下に向けて第2の偏向角θbをもって偏向した音響走査線bに沿って超音波を被検体に2回送信し、それぞれの反射エコーを受信する。受信した反射エコーは電気信号(1回目と2回目の受信信号)に変換される。変換された電気信号(1回目と2回目の受信信号)は記憶部110に記憶される。 [Steps 4 and 5]: Based on a command from the control unit 100, the probe 101 performs the second deflection from the upper left to the lower right in FIG. 3 with respect to the measurement point at the position X in the subject. Ultrasonic waves are transmitted to the subject twice along the acoustic scanning line b deflected at the angle θb, and each reflected echo is received. The received reflected echo is converted into an electrical signal (first and second received signals). The converted electrical signals (first and second received signals) are stored in the storage unit 110.

〔ステップ6〕:移動量演算部111は、音響走査線bについて記憶された1回目と2回目の受信信号を取得し、これら2つの受信信号の位相差から、上述の式1に基づいて、音響走査線bに沿った方向(第2の偏向方向)に関する位置Xの移動量(ベクトル量)ΔX(b)を計算する。計算された移動量ΔX(b)は、記憶部112と位置追跡部113に送信される。 [Step 6]: The movement amount calculation unit 111 acquires the first and second reception signals stored for the acoustic scanning line b, and based on the above-described Expression 1 from the phase difference between these two reception signals. A movement amount (vector amount) ΔX (b) of the position X in the direction along the acoustic scanning line b (second deflection direction) is calculated. The calculated movement amount ΔX (b) is transmitted to the storage unit 112 and the position tracking unit 113.

〔ステップ7〕:移動量ΔX(a)とΔX(b)は、計測点の真の移動量の音響走査線aおよび音響走査線b方向の投影(移動成分)である。そこで、位置追跡部113は、移動量演算部111又は記憶部112から出力された移動量ΔX(a)、ΔX(b)を合成(ベクトル合成)して真の移動量ΔXを計算する。 [Step 7]: Movement amounts ΔX (a) and ΔX (b) are projections (movement components) in the acoustic scanning line a and acoustic scanning line b directions of the true movement amount of the measurement point. Therefore, the position tracking unit 113 calculates the true movement amount ΔX by combining (vector combining) the movement amounts ΔX (a) and ΔX (b) output from the movement amount calculation unit 111 or the storage unit 112.

〔ステップ8〕:次に、位置追跡部113は、移動前の組織位置Xに移動量ΔXを加えて、移動後の位置X’を計算する。 [Step 8]: Next, the position tracking unit 113 calculates the post-movement position X ′ by adding the movement amount ΔX to the tissue position X before the movement.

以上のステップ1〜8を繰り返し、被検体内の計測点の位置を追跡する。例えば、位置X’を通る左方向に偏向させた音響走査線a’(音響走査線aと平行な音響走査線)に沿う方向に2回、右方向に偏向させた音響走査線b’(音響走査線bと平行な音響走査線)に沿う方向に2回超音波を送受信し、次の真の移動量ΔX’を求め、移動量ΔX’を位置X’に加算することで次の位置X”を求める。   The above steps 1 to 8 are repeated to track the position of the measurement point in the subject. For example, the acoustic scanning line b ′ (acoustics) deflected to the right twice, in the direction along the acoustic scanning line a ′ (acoustic scanning line parallel to the acoustic scanning line a) deflected leftward through the position X ′. The ultrasonic wave is transmitted and received twice in the direction along the scanning line b), the next true movement amount ΔX ′ is obtained, and the movement amount ΔX ′ is added to the position X ′ to obtain the next position X. ”

〔ステップ9〕:音響走査線の間隔は、探触子101に設けられている圧電変換素子の配置間隔に依存する。そのため、例えば図3に示すように、移動後の位置X’が、一方の音響走査線a’上又はその極近傍に存在するが、他方の音響走査線b’上又はその極近傍に存在せず、音響走査線b、b’の中間に存在することがある。したがって、制御部100は、次の音響走査線を決定する際、計算された移動後の位置X’からこの位置X’に最も近い音響走査線a’,b’を次の音響走査線として採用する。そして、音響走査線a’,b’が交差する位置x’の移動量Δx’(a)、Δx’(b)、及び移動量Δx’を求め、この移動量Δx’を位置X’に加算して移動後の位置X”を求める。 [Step 9]: The interval between the acoustic scanning lines depends on the arrangement interval of the piezoelectric transducers provided in the probe 101. Therefore, for example, as shown in FIG. 3, the moved position X ′ exists on one acoustic scanning line a ′ or in the vicinity thereof, but does not exist on the other acoustic scanning line b ′ or in the vicinity thereof. In some cases, it may exist between the acoustic scanning lines b and b ′. Therefore, when determining the next acoustic scanning line, the control unit 100 employs the acoustic scanning lines a ′ and b ′ closest to the position X ′ from the calculated position X ′ after movement as the next acoustic scanning lines. To do. Then, the movement amounts Δx ′ (a) and Δx ′ (b) and the movement amount Δx ′ of the position x ′ where the acoustic scanning lines a ′ and b ′ intersect are obtained, and the movement amount Δx ′ is added to the position X ′. Thus, the position X ″ after the movement is obtained.

この方法に代えて、例えば図4に示すように移動後の位置X’が音響走査線b、b’の中間にある場合、音響走査線b上にある位置x(a’,b)の移動量Δx’(a’,b)と音響走査線b’上にある位置x’(a’,b’)の移動量Δx’(a’,b’)を求め、これら2つの移動量Δx(a’,b)とΔx’(a’,b’)の平均値または線形補間した値を音響走査線b’に沿った方向の移動量ΔX’(b)としてもよい。   Instead of this method, for example, as shown in FIG. 4, when the moved position X ′ is in the middle of the acoustic scanning lines b and b ′, the movement of the position x (a ′, b) on the acoustic scanning line b is performed. The movement amount Δx ′ (a ′, b ′) of the amount Δx ′ (a ′, b ′) and the position x ′ (a ′, b ′) on the acoustic scanning line b ′ is obtained, and these two movement amounts Δx ( An average value of a ′, b) and Δx ′ (a ′, b ′) or a value obtained by linear interpolation may be used as the movement amount ΔX ′ (b) in the direction along the acoustic scanning line b ′.

なお、以上の説明では、まず音響走査線aに沿った方向に2回超音波を発振して移動量ΔXaを求め、次に音響走査線bに沿った方向に2回超音波を発振して移動量ΔXbを求めたが、まず音響走査線a,bに沿ってそれぞれ1回超音波を発振し、次に、同様に音響走査線a,bに沿ってそれぞれ1回超音波を発振し、その後、それぞれの音響走査線a,bに沿った方向の移動量ΔXa、ΔXb及び真の移動量ΔXを計算してもよい。   In the above description, the ultrasonic wave is first oscillated twice in the direction along the acoustic scanning line a to obtain the movement amount ΔXa, and then the ultrasonic wave is oscillated twice in the direction along the acoustic scanning line b. The amount of movement ΔXb was calculated. First, the ultrasonic waves were oscillated once along the acoustic scanning lines a and b, respectively, and then the ultrasonic waves were oscillated once along the acoustic scanning lines a and b, respectively. Thereafter, the movement amounts ΔXa and ΔXb and the true movement amount ΔX in the direction along the acoustic scanning lines a and b may be calculated.

また、音響走査線aと音響走査線bに沿った移動量(例えば、ΔXaとΔXb)の検出時間は僅かに異なる。したがって、検出時間のずれに伴う誤差を出来るだけ少なくするために、音響走査線aに沿った方向に3回、音響走査線bに沿った方向に3回の送信を行ない、それぞれ2つの移動量(ΔXa1とΔXa2,ΔXb1とΔXb2)を求め、これら2つを補間(例えば線形補間)することにより同じ時刻の移動量ΔXa,ΔXbを求めることができる。このようにすることにより、さらに精度よく2次元の動きを追跡することができる。   Further, the detection times of the movement amounts (for example, ΔXa and ΔXb) along the acoustic scanning line a and the acoustic scanning line b are slightly different. Therefore, in order to reduce the error due to the difference in detection time as much as possible, transmission is performed three times in the direction along the acoustic scanning line a and three times in the direction along the acoustic scanning line b, and each of the two movement amounts. By obtaining (ΔXa1 and ΔXa2, ΔXb1 and ΔXb2) and interpolating these two (for example, linear interpolation), the movement amounts ΔXa and ΔXb at the same time can be obtained. By doing so, it is possible to track the two-dimensional movement with higher accuracy.

〔2次元追跡〕
2次元に分布した計測点の位置を2次元追跡する方法について、図5から図7を用いて説明する。図5に示すように、図中左方向および右方向に偏向させた音響走査線を複数(a1〜an,b1〜bn)設定し、被検体内を走査する。音響走査線の走査順序はa1,a2,…,an,b1,b2,…,bn(nは走査線本数,図3の場合はn=6である。)としてもよいし、a1,b1,a2,b2,…,an,bnとしてもよい。このように、1回の2次元走査で左右両方向に偏向したすべての音響走査線(a1〜an,b1〜bn)を1回づつ発振する。この一回の2次元走査を「1フレーム」とし、これを繰り返し行うことで、2次元分布した計測点の動きを追跡する。なお、図5において、音響走査線aと音響走査線bの交点が計測点の初期位置であり、各計測が白丸で示してある。
[Two-dimensional tracking]
A method for two-dimensionally tracking the positions of measurement points distributed two-dimensionally will be described with reference to FIGS. As shown in FIG. 5, a plurality (a1 to an, b1 to bn) of acoustic scanning lines deflected leftward and rightward in the figure are set, and the inside of the subject is scanned. The scanning order of the acoustic scanning lines may be a1, a2,..., An, b1, b2,..., Bn (n is the number of scanning lines, n = 6 in FIG. 3), or a1, b1, It is good also as a2, b2, ..., an, bn. In this way, all the acoustic scanning lines (a1 to an, b1 to bn) deflected in the left and right directions by one two-dimensional scanning are oscillated once. This one-dimensional two-dimensional scanning is set as “one frame”, and the movement of the measurement points distributed two-dimensionally is traced by repeating this. In FIG. 5, the intersection of the acoustic scanning line a and the acoustic scanning line b is the initial position of the measurement point, and each measurement is indicated by a white circle.

計測点の追跡の一例として、音響走査線a6とb2の交点位置Xを初期位置とした計測点の追跡について図6を用いて説明する。フレーム間の時間間隔(同じ音響走査線に沿った超音波の送受信間隔)をΔTとする。まず、1フレーム目と2フレーム目の音響走査線a6に沿った方向と音響走査線b2に沿った方向の受信信号から、上述のようにして、位置Xの移動量ΔX及び移動後の位置X’を求める。次に、2フレーム目と3フレーム目の音響走査線a4に沿った方向と音響走査線b3に沿った方向の受信信号から、移動量ΔX’及び移動後の位置X”を求める。この操作を繰り返すことで、計測点の動きを追跡できる。そして、すべての計測点について同様の操作を行うことで、2次元に分布した計測点位置の2次元移動追跡を行うことができる。また、検出時間のずれに起因する誤差を解消するために、上述のように、それぞれの偏向方向に超音波を3回送受信し、それぞれの方向について取得された2つの移動量を補間(例えば線形補間)することにより同じ時刻の移動量を求めることが好ましい。   As an example of tracking of measurement points, tracking of measurement points with an intersection position X of acoustic scanning lines a6 and b2 as an initial position will be described with reference to FIG. A time interval between frames (a transmission / reception interval of ultrasonic waves along the same acoustic scanning line) is assumed to be ΔT. First, from the received signals in the directions along the acoustic scanning line a6 and the acoustic scanning line b2 in the first frame and the second frame, the movement amount ΔX of the position X and the position X after the movement are obtained as described above. Ask for '. Next, the movement amount ΔX ′ and the moved position X ″ are obtained from the received signals in the directions along the acoustic scanning line a4 and the acoustic scanning line b3 in the second and third frames. By repeating, the movement of the measurement point can be tracked, and the two-dimensional movement tracking of the measurement point positions distributed in two dimensions can be performed by performing the same operation for all the measurement points. In order to eliminate the error caused by the deviation, the ultrasonic wave is transmitted and received three times in each deflection direction as described above, and the two movement amounts acquired in each direction are interpolated (for example, linear interpolation). It is preferable to obtain the movement amount at the same time.

図7は、複数の計測点の動きを2次元追跡した一例を示す。黒丸は計測点であり、角の計測点は白丸で示す。図7(a)は計測点の初期位置、図7(b)は1フレーム目と2フレーム目の受信信号から求めたΔT後の計測点位置の分布、図7(c)は2フレーム目と3フレーム目の受信信号から求めた2ΔT後の計測点位置の分布である。右上左下方向では圧縮される方向、左上右下方向では伸張される方向に動いていることを正確に追跡することができていることがわかる。   FIG. 7 shows an example of two-dimensional tracking of the movement of a plurality of measurement points. Black circles are measurement points, and corner measurement points are indicated by white circles. 7A shows the initial position of the measurement point, FIG. 7B shows the distribution of the measurement point position after ΔT obtained from the received signals of the first frame and the second frame, and FIG. 7C shows the second frame. This is a distribution of measurement point positions after 2ΔT obtained from the received signal of the third frame. It can be seen that it is possible to accurately track the movement in the compression direction in the upper right and lower left direction and the expansion direction in the upper left and lower right direction.

〔3次元追跡〕
本発明によれば、被検体内の組織の動きを3次元追跡することもできる。3次元追跡では、図8に示すように、圧電変換素子120が2次元状に配置された2次元アレイ探触子121を用い、計測点(位置X)に対して、同一平面状に無い3方向の音響走査線a,b,cに沿う方向に超音波を送受信し、得られた3つの受信信号からそれぞれの音響走査線に沿う方向の移動量(ベクトル量)ΔXa,ΔXb,ΔXcを求め、これら3つの移動量を合成(ベクトル合成)して真の3次元移動量ΔXを求め、この3次元移動量ΔXを初期位置Xに加算して新たな位置X’を求める。この処理を繰り返すことで計測点位置を3次元的に追跡することができる。
[3D tracking]
According to the present invention, the movement of the tissue in the subject can also be tracked three-dimensionally. In the three-dimensional tracking, as shown in FIG. 8, a two-dimensional array probe 121 in which the piezoelectric transducers 120 are arranged two-dimensionally is used, and the measurement point (position X) is not in the same plane. Ultrasonic waves are transmitted and received in the direction along the acoustic scanning lines a, b, and c, and the movement amounts (vector quantities) ΔXa, ΔXb, and ΔXc in the direction along the acoustic scanning lines are obtained from the obtained three received signals. Then, these three movement amounts are combined (vector combination) to obtain a true three-dimensional movement amount ΔX, and this three-dimensional movement amount ΔX is added to the initial position X to obtain a new position X ′. By repeating this process, the measurement point position can be tracked three-dimensionally.

図9は、図8を用いて説明した3次元追跡を拡張した例を示す。図において、矢印線は音響走査線であり、点線は1フレームの音響走査によって走査されるボリューム(体積領域)である。まず、図9(a)に示すように、2次元アレイ探触子121から無偏向の超音波群を用いてボリューム(点線で示す領域)を走査する。次に、図9(b)に示すように、図の右上から左下に向かって偏向した超音波群を用いてボリュームを走査する。次に、図9(c)に示すように、図の左上から右下に偏向した超音波群を用いてボリュームを走査する。これら3回の走査から得られたデータ(受信信号)を用い、すべての計測点に対して、図8を参照して説明した方法により3方向の移動量を求め、それら3つの移動量から各計測点の真の3次元移動量を求めると共に、この3次元移動量を各計測点の初期位置に加算してすべての計測点の新たな位置を求める。   FIG. 9 shows an example in which the three-dimensional tracking described with reference to FIG. 8 is extended. In the figure, an arrow line is an acoustic scanning line, and a dotted line is a volume (volume region) scanned by one frame of acoustic scanning. First, as shown in FIG. 9A, a volume (area indicated by a dotted line) is scanned from the two-dimensional array probe 121 using a non-deflection ultrasonic wave group. Next, as shown in FIG. 9B, the volume is scanned using an ultrasonic wave group deflected from the upper right to the lower left in the figure. Next, as shown in FIG. 9C, the volume is scanned using an ultrasonic wave group deflected from the upper left to the lower right in the figure. Using the data (reception signal) obtained from these three scans, the movement amount in three directions is obtained for all measurement points by the method described with reference to FIG. The true three-dimensional movement amount of the measurement point is obtained, and this three-dimensional movement amount is added to the initial position of each measurement point to obtain new positions of all measurement points.

3次元移動追跡は、特に心臓の診断に有用であり、3次元的な動きをする心臓の動きを精度よく計測することで、心機能の定量的な診断を行なうことができる。なお、被検体組織中の音速は有限であるため、すべてのボリュームを走査すると、各計測点に対する超音波の繰り返し周波数が低下するという問題がある。これに対しては、計測領域を狭めたり、従来用いられている並列受信の技術などを行なうことにより解決することが可能である。   The three-dimensional movement tracking is particularly useful for the diagnosis of the heart, and the heart function can be quantitatively diagnosed by accurately measuring the movement of the heart that moves three-dimensionally. Since the sound speed in the subject tissue is finite, there is a problem that when all the volumes are scanned, the repetition frequency of the ultrasonic wave at each measurement point decreases. This can be solved by narrowing the measurement area or performing a parallel reception technique used conventionally.

〔血管壁の診断〕
図10、11を用いて、本方式を血管壁の診断に応用した場合を説明する。図10(b)に示すように、実際の血管壁は、心臓の動きに引っ張られたり、血流による摩擦のために血管の軸方向の動きも伴い、結果として図示するような斜め方向の動き、正確には図中両矢印を長軸とする楕円に類似の動きをする。特に頚動脈では、このような楕円動作が顕著である。しかし、特許文献1に開示されている血管壁診断は、図10(a)に示すように、心拍による血圧変動によって血管壁が径方向にのみの動作するものと仮定しておおり、血管壁の動きを正確に把握できないという問題がある。
[Diagnosis of blood vessel wall]
The case where this method is applied to the diagnosis of the blood vessel wall will be described with reference to FIGS. As shown in FIG. 10 (b), the actual blood vessel wall is pulled by the movement of the heart or accompanied by the movement of the blood vessel in the axial direction due to friction caused by blood flow. To be precise, it moves similar to an ellipse having a major axis with a double-headed arrow in the figure. Especially in the carotid artery, such an elliptical movement is remarkable. However, the blood vessel wall diagnosis disclosed in Patent Document 1 assumes that the blood vessel wall operates only in the radial direction due to blood pressure fluctuation due to heartbeat, as shown in FIG. There is a problem that it is impossible to accurately grasp the movement of the.

そこで、本発明では、まず図10(c)に示すように、2種類の所定の偏向角を持った音響走査線に沿う方向に超音波を送受信し、その受信信号をもって被検体組織の2次元的な動きを追跡し、血管壁および周辺組織の動きを検出する。次いで、図10(d)に示すように、血管壁の移動方向に平行となるように偏向させた1種類の音響走査線に沿う方向に超音波を送受信し、その受信信号をもって被検体組織の追跡を行ない、これにより血管壁の歪み、弾性率、粘性率、移動速度、厚みなどの組織性状パラメータを求める。   Therefore, in the present invention, as shown in FIG. 10 (c), first, ultrasonic waves are transmitted and received in directions along two acoustic scanning lines having predetermined deflection angles, and the received signals are used to perform two-dimensional analysis of the subject tissue. The movement of the blood vessel and surrounding tissue is detected. Next, as shown in FIG. 10 (d), ultrasonic waves are transmitted and received in a direction along one kind of acoustic scanning line deflected so as to be parallel to the moving direction of the blood vessel wall, and the received signal of the subject tissue is received. Tracking is performed, thereby obtaining tissue property parameters such as strain, elastic modulus, viscosity, moving speed, and thickness of the blood vessel wall.

例えば、図10(c)の音響走査をした場合、1フレームあたりの音響走査線は16本である。また、図10(d)の音響走査をした場合、1フレームあたりの音響走査線は8本である。したがって、以上のように、まず図10(c)に示すように2種類の偏向角を有する音響走査線に沿って超音波を送受信して血管壁の移動方向を決定し、以後この移動方向に沿って音響走査線を走査することにより、フレーム間の時間間隔ΔTを半分にすることができ、これにより動きの速い被検体にも対応することができる。   For example, when the acoustic scanning in FIG. 10C is performed, there are 16 acoustic scanning lines per frame. Further, when the acoustic scanning of FIG. 10D is performed, there are eight acoustic scanning lines per frame. Therefore, as described above, first, as shown in FIG. 10C, ultrasonic waves are transmitted and received along acoustic scanning lines having two kinds of deflection angles to determine the moving direction of the blood vessel wall. By scanning the acoustic scanning line along the line, the time interval ΔT between the frames can be halved, and thus it is possible to deal with a fast-moving subject.

具体的には、まず超音波送受信停止状態から超音波送受信状態へ移行した直後、図10(c)に示す超音波走査を数心拍の間行なって2次元的な動きを求めた後、血管壁の動きに平行となるように図10(d)に示す走査を行なって組織性状パラメータを求める。図10(c)に示す走査は、その後も定期的、あらかじめ決められた時間ごと、あるいはあらかじめ決められた心拍数ごとに行なうことが好ましい。このようにすることにより、正確に血管壁の動きを追跡することができ、精度の良い血管壁の組織性状パラメータを得ることができる。   Specifically, immediately after shifting from the ultrasonic transmission / reception stop state to the ultrasonic transmission / reception state, the ultrasonic scanning shown in FIG. 10C is performed for several heartbeats to obtain a two-dimensional movement, and then the blood vessel wall The tissue property parameter is obtained by performing the scanning shown in FIG. It is preferable that the scanning shown in FIG. 10C is performed periodically thereafter, every predetermined time, or every predetermined heart rate. By doing so, it is possible to accurately track the movement of the blood vessel wall, and to obtain a highly accurate tissue property parameter of the blood vessel wall.

図11は、超音波診断装置を用いて、血管壁の弾性率を計測した結果の一例を表示したモニタ画面である。図において、モニタ上には血管壁のモノクロ断層画像200に重畳して、当該部位の弾性率の分布を表す弾性率画像201がカラーで表示される。弾性率画像は図10に示した方法により正確な弾性率が求められ、弾性率に応じた色が付与されている。このように本発明により、血管壁の弾性率を表示できるので、正確な診断が可能とすることができる。   FIG. 11 is a monitor screen displaying an example of the result of measuring the elastic modulus of the blood vessel wall using the ultrasonic diagnostic apparatus. In the figure, an elastic modulus image 201 representing the distribution of elastic modulus of the part is displayed in color on the monitor in a superimposed manner on the monochrome tomographic image 200 of the blood vessel wall. The elastic modulus image is obtained with an accurate elastic modulus by the method shown in FIG. 10, and a color corresponding to the elastic modulus is given. As described above, according to the present invention, since the elastic modulus of the blood vessel wall can be displayed, an accurate diagnosis can be made.

なお、図1では本発明の実施に必要な複数の機能を独立したブロックとして示したが、この限りではなく、例えば、制御部100、断層画像処理部104、組織追跡部105、画像合成部106、組織性状計算部108などはCPU上でソフトウェアとして実現することができる。   In FIG. 1, a plurality of functions necessary for implementing the present invention are shown as independent blocks. However, the present invention is not limited to this. For example, the control unit 100, the tomographic image processing unit 104, the tissue tracking unit 105, and the image synthesis unit 106 are used. The tissue property calculation unit 108 and the like can be realized as software on the CPU.

以上説明したように、本発明によれば、被検体組織の2次元の動きをより正確に追跡することができ、これを用いて被検体組織の歪みや弾性率、粘性率、血管壁の厚み、移動速度などの組織性状を精度よく求めることができるという効果を有し、被検体組織の組織性状を計測する超音波診断装置として有用である。   As described above, according to the present invention, it is possible to more accurately track the two-dimensional movement of the subject tissue, and using this, the strain, elastic modulus, viscosity, and vessel wall thickness of the subject tissue can be used. It has an effect that tissue properties such as moving speed can be obtained with high accuracy, and is useful as an ultrasonic diagnostic apparatus for measuring tissue properties of a subject tissue.

本発明に係る超音波診断装置の機能ブロック図。1 is a functional block diagram of an ultrasonic diagnostic apparatus according to the present invention. 超音波診断装置の組織追跡処理を示すフローチャート。The flowchart which shows the tissue tracking process of an ultrasonic diagnosing device. 超音波診断装置による2次元位置追跡の説明図。Explanatory drawing of two-dimensional position tracking by an ultrasonic diagnostic apparatus. 超音波診断装置による2次元位置追跡の説明図。Explanatory drawing of two-dimensional position tracking by an ultrasonic diagnostic apparatus. 音響走査線と計測位置の説明図。Explanatory drawing of an acoustic scanning line and a measurement position. 2次元分布した計測位置の2次元位置追跡の説明図。Explanatory drawing of two-dimensional position tracking of the measurement position distributed two-dimensionally. 2次元分布した計測位置の2次元位置追跡結果の一例を示す図。The figure which shows an example of the two-dimensional position tracking result of the measurement position distributed two-dimensionally. 本発明に係る超音波診断装置による3次元位置追跡の説明図。Explanatory drawing of the three-dimensional position tracking by the ultrasonic diagnosing device which concerns on this invention. 超音波診断装置による3次元位置追跡の走査方法の説明図。Explanatory drawing of the scanning method of the three-dimensional position tracking by an ultrasonic diagnosing device. 血管壁の移動方向と超音波診断装置における走査方法の説明図。Explanatory drawing of the scanning method in the moving direction of a blood-vessel wall and an ultrasonic diagnosing device. 血管壁の計測結果の一例を示す図。The figure which shows an example of the measurement result of a blood vessel wall. 位相差から組織追跡を行なう基本動作説明図。Explanatory drawing of basic operation for performing tissue tracking from phase difference. 組織追跡波形から歪み量を求める基本動作説明図。The basic operation explanatory drawing which calculates | requires distortion amount from a tissue tracking waveform.

符号の説明Explanation of symbols

100:制御部、101:探触子、102:送信部、103:受信部、104:断層画像処理部、105:組織追跡部、106:画像合成部、107:モニタ、108:組織性状計算部、110:記憶部、111:移動量演算部、112:記憶部、113:位置追跡部、200:断層画像、201:弾性率画像。
DESCRIPTION OF SYMBOLS 100: Control part, 101: Probe, 102: Transmission part, 103: Reception part, 104: Tomographic image processing part, 105: Tissue tracking part, 106: Image composition part, 107: Monitor, 108: Tissue property calculation part 110: storage unit, 111: movement amount calculation unit, 112: storage unit, 113: position tracking unit, 200: tomographic image, 201: elastic modulus image.

Claims (8)

被検体内に設定された計測点に対して少なくとも2つの異なる偏向角をもって超音波を送受信する手段と、
各々の超音波送受信方向に沿った計測点の移動量を求める手段と、
異なる偏向角をもって送受信した超音波送受信方向に沿った少なくとも2つの移動量から上記計測点の2次元又は3次元の移動量を求める手段と、
上記計測点の2次元又は3次元の移動量を上記計測点の移動前の位置に加えて上記計測点の2次元又は3次元の動きを追跡する手段を備えたことを特徴とする超音波診断装置。
Means for transmitting and receiving ultrasound with at least two different deflection angles with respect to a measurement point set in the subject;
Means for determining the amount of movement of the measurement point along each ultrasonic transmission / reception direction;
Means for obtaining a two-dimensional or three-dimensional movement amount of the measurement point from at least two movement amounts along the ultrasonic transmission / reception direction transmitted / received with different deflection angles;
An ultrasonic diagnosis comprising means for tracking the two-dimensional or three-dimensional movement of the measurement point by adding the two-dimensional or three-dimensional movement amount of the measurement point to the position before the measurement point is moved. apparatus.
異なる偏向角を与えた少なくとも2つの超音波のそれぞれによって被検体を断面又はボリュームを走査する手段と、
上記被検体内に2次元又は3次元に設定された複数の計測点のそれぞれの超音波送受信方向の移動量を求める手段と、
上記複数の計測点のそれぞれについて、異なる偏向角を有する超音波送受信方向に沿った少なくとも2つの移動量から計測点の2次元又は3次元の移動量を求める手段と、
上記複数の計測点のそれぞれについて、上記2次元又は3次元の移動量を計測点の移動前の位置に加えて2次元又は3次元の動きを追跡する手段を備えたことを特徴とする超音波診断装置。
Means for scanning a cross-section or volume of the subject by each of at least two ultrasound waves provided with different deflection angles;
Means for obtaining a movement amount in the ultrasonic transmission / reception direction of each of a plurality of measurement points set in a two-dimensional or three-dimensional manner in the subject;
Means for obtaining a two-dimensional or three-dimensional movement amount of the measurement point from at least two movement amounts along the ultrasonic transmission / reception direction having different deflection angles for each of the plurality of measurement points;
Ultrasonic waves characterized by comprising means for tracking the two-dimensional or three-dimensional movement of each of the plurality of measurement points by adding the two-dimensional or three-dimensional movement amount to the position before the measurement point is moved. Diagnostic device.
上記超音波送受信方向に沿った計測点の移動量、又は上記計測点の2次元又は3次元の移動量、若しくはそれらの両方を記憶する手段を備えたことを特徴とする請求項1又は2に記載の超音波診断装置。   The apparatus according to claim 1 or 2, further comprising means for storing a movement amount of the measurement point along the ultrasonic transmission / reception direction, a two-dimensional or three-dimensional movement amount of the measurement point, or both. The ultrasonic diagnostic apparatus as described. 上記2つの超音波送受信方向に沿った計測点の移動量を求める手段は、それぞれの超音波送受信方向について計測点の移動量を複数回求めると共にこれら複数回求めた移動量を補間して、上記2つの超音波送受信方向に沿った計測点の移動量を時間差無く求めることを特徴とする請求項1〜3のいずれかに記載の超音波診断装置。   The means for obtaining the movement amount of the measurement point along the two ultrasonic transmission / reception directions obtains the movement amount of the measurement point for each ultrasonic transmission / reception direction a plurality of times and interpolates the movement amount obtained for the plurality of times, The ultrasonic diagnostic apparatus according to claim 1, wherein the movement amount of the measurement point along two ultrasonic transmission / reception directions is obtained without a time difference. 上記検出した2次元的または3次元的な動きを追跡した結果から被検体の組織性状を表す値を算出する手段をさらに有し、上記組織性状を表す値は、少なくとも被検体組織の厚み変化量、速度、歪み、弾性率、粘性率のいずれかであることを特徴とする請求項1〜4のいずれか1項記載の超音波診断装置。   The apparatus further includes means for calculating a value representing the tissue property of the subject from the result of tracking the detected two-dimensional or three-dimensional movement, and the value representing the tissue property is at least a thickness change amount of the subject tissue. The ultrasonic diagnostic apparatus according to claim 1, wherein the ultrasonic diagnostic apparatus is any one of a velocity, a strain, an elastic modulus, and a viscosity. 上記2次元または3次元の動きを追跡した後は、被計測組織の動きと平行な方向に偏向させた超音波をもって被計測組織の動きを追跡することを特徴とする請求項1〜5のいずれかに記載の超音波診断装置。   6. After tracking the two-dimensional or three-dimensional movement, the movement of the measured tissue is tracked with an ultrasonic wave deflected in a direction parallel to the movement of the measured tissue. An ultrasonic diagnostic apparatus according to claim 1. 上記2次元または3次元の動きの追跡は、超音波送受信中定期的に行なうことを特徴とする請求項6記載の超音波診断装置。   The ultrasonic diagnostic apparatus according to claim 6, wherein the tracking of the two-dimensional or three-dimensional movement is periodically performed during ultrasonic transmission / reception. 上記2次元または3次元の動きの追跡は、超音波送受信停止時から超音波送受信を開始した直後に行なうことを特徴とする請求項6又は7記載の超音波診断装置。
8. The ultrasonic diagnostic apparatus according to claim 6, wherein the tracking of the two-dimensional or three-dimensional movement is performed immediately after the ultrasonic transmission / reception is started after the ultrasonic transmission / reception is stopped.
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