JP2003035776A - How to support radiation screening - Google Patents

Abstract

(57) [Summary] [Problem] To reduce the burden on the operation of radiation screening and increase the number of examinees. A hospital installs a plurality of inspection devices 3 and performs an inspection of a subject who has been administered a radiopharmaceutical containing a radionuclide that emits a proton beam. The radiological examination support company includes a plurality of examinees who can be examined at one time based on the information on each examinee obtained from the hospital (the radiopharmaceuticals to be administered) and the number of examination devices, using the processing device 12. An examination schedule including an examination time is created for each group of examinees. The radionuclide amount required for the group of examinees is calculated based on the total weight of the examinees included in the group of examinees. Using the information on the radionuclide amount and the test schedule, the radiological screening support company targets the manufacture of radionuclides, the manufacture of radiopharmaceuticals, the administration of the radiopharmaceuticals to the relevant examinees, and the inspection by the test device 3 Create an operation schedule.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for assisting radiation screening, and in particular, Positron Emission Tomography using a radiopharmaceutical containing a radionuclide that emits a positron with a short half-life.
The present invention relates to a radiation screening support method suitable for supporting radiation screening using (positron emission type imaging), hereinafter referred to as PET.

[0002]

2. Description of the Related Art In recent years, PET using the above radiopharmaceuticals
Has been attracting attention for its application to cancer screening. Radionuclides that emit positrons with a short half-life included in the radiopharmaceutical include ¹¹ C (half-life: 20 minutes) and ¹³ N (half-life:
10 minutes), ¹⁵ O (half-life: 2 minutes), ¹⁸ F (half-life: 11)
0 minutes). This PET cancer screening is based on "PET Communications 1999 SUMMER" issued by the Institute of Advanced Medical Technology.
No. 27 ", pp. 1-14.

Conventionally, a certain amount of radioisotope (R
adio Isotope: hereinafter referred to as RI) is manufactured, stored, and used by dividing into several times. That RI
Are the radionuclides mentioned above. When diagnosing cancer by a medical examination using PET (hereinafter referred to as PET diagnosis),
Manufacturing of RI required for PET diagnosis (RI
Manufacturing), synthesis of radiopharmaceutical using the RI (drug synthesis), administration of radiopharmaceutical to the examinee (drug administration), waiting for the radiopharmaceutical to reach an equilibrium state in the examinee (waiting) ), Inspection, and image processing. The test is to detect γ-rays emitted from the body of a medical examinee who has been administered a radiopharmaceutical with a radiation detector. Gamma rays are generated when the positrons emitted from RI of the radiopharmaceutical collected in the affected area of cancer disappear.

In order to improve the efficiency of the most time-consuming examination in PET diagnosis, it has been considered to shift the time of administration of a drug to a plurality of examinees. That is, a radiopharmaceutical is synthesized by using the RI manufactured at one time, and the radiopharmaceutical is administered to a plurality of medical examinees at different times.

However, until now, it cannot be said that an efficient method of operating a device used for PET diagnosis (hereinafter referred to as a PET system) has been sufficiently studied. It can be said from now on that a medical-related institution (a hospital, a clinic, a medical examination facility, etc.) that has introduced a PET system for conducting a medical examination for cancer, etc. by PET will examine the operation and operation method of the PET system. The PET system detects an RI manufacturing device for manufacturing RI, a radiopharmaceutical synthesizing device for synthesizing a radiopharmaceutical containing RI, and γ-rays emitted from the body of a medical examinee due to the radiopharmaceutical An inspection device for reconstructing a tomographic image of a person to be examined based on the value is provided.

[0006]

When a medical-related institution operates the PET system introduced to perform a medical examination for cancer, etc.,
As mentioned above, RI manufacturing, drug synthesis, drug administration, waiting,
There is a wide variety of work to be performed such as inspection and image processing, and the required work amount is large. To reduce the running cost of the PET system and to reduce the amount of work required for operation, PE
This is an important issue for efficient operation of the T system.
These operations are indispensable for conducting a medical examination for cancer and the like. However, medical institutions need to perform the above work in PET diagnosis, where they should concentrate on medical diagnosis and treatment actions such as medical treatment and diagnosis that should be performed. In particular, the operation and operation of the PET system imposes a great burden on medical institutions. With the increase in the number of people undergoing PET diagnosis,
Developing efficient driving methods for PET systems is
It is also important for extending the life of the PET system and effectively operating medical institutions.

An object of the present invention is to provide a method for supporting radiation screening, which can reduce the burden on the operation of radiation screening and increase the number of examinees.

[0008]

Means for Solving the Problems The feature of the present invention to achieve the above-mentioned object is that a radionuclide from a subject who has been administered a radiopharmaceutical including a radionuclide that emits a proton beam, which is installed in a medical institution. Within the range of the number of inspection devices that detect γ-rays emitted due to, the examinees to be inspected at one time are selected by the information processing device using the information on the radiopharmaceutical administered to the examinees, The selected examinees to be inspected at one time are set as one examinee group, the inspection time by the inspection device is set for each examinee group, and the inspection schedule for the examinees is created by the processing device. It is in.

[0009] Since the examiners included in the group of examinees are selected in consideration of the information about the radiopharmaceuticals to be administered to the examinees, the radiopharmaceuticals to be administered to the examinees included in the group of examinees are unified. can do. Therefore, the efficiency of radiation screening is improved, and the number of examinees who undergo radiation screening is increased. The examination time of the examinee is set in consideration of the number of examination devices installed in the medical institution, which also leads to an increase in the number of examinees. In addition, because the examinees included in one examinee group are selected using the information on the radiopharmaceuticals to be administered to the examinees and the examination time is set for each examinee group, the radiation checkup operation is performed. It is possible to create an inspection schedule that can reduce the burden on employees.

[0010] Preferably, it is desirable that the selection of the examinees included in the examinee group is performed by selecting the examinees who administer the same kind of radiopharmaceutical by the processing device. Since the examinees included in the examinee group are the examinees who administer the same type of radiopharmaceutical, the same type of radiopharmaceutical may be manufactured for the examinee group. This facilitates the production of radiopharmaceuticals.

[0011] Preferably, for each group of examinees to which different types of radiopharmaceuticals containing the same type of radionuclide are administered, the group of examinees to which a certain type of radiopharmaceutical is administered It is desirable to create the examination schedule so as to perform the examination of another group of examinees to whom another type of the radiopharmaceutical is administered subsequent to the above examination. If the types of radionuclides used are the same, multiple testee groups with different types of administered radiopharmaceuticals will continue to be tested. It is only necessary to produce the radionuclide, which facilitates the production and improves the inspection efficiency.

[0012] Preferably, it is desirable to set the examination time for each group of examinees according to the half-life of the radionuclide contained in the radiopharmaceutical. In particular, it is desirable to set the examination time to an earlier time zone for a group of examinees to whom a radiopharmaceutical including a radionuclide having a short half-life is administered. Since the radionuclide with a short half-life disappears quickly, the probability of affecting the examination of the examinee who has been administered the radiopharmaceutical containing the radionuclide with a long half-life is very small.

Preferably, the inspection schedule is created
It is desirable for a radiation screening support company to receive a request from a medical-related institution. The medical institution does not need to create the inspection schedule, and does not have to perform the complicated work associated with the creation. Therefore, the medical-related institution can reduce the burden on the medical-related institution in the radiation screening using the radionuclide that emits a proton beam.

Preferably, the amount of the corresponding radionuclide required for the examination of all the examinees included in the group of examinees is calculated by the processing device based on the total weight of the examinees included in the group of examinees. However, based on the amount of this radionuclide and the information on the inspection schedule, the processing device manufactures the radionuclide, manufactures the radiopharmaceutical, and administers this radiopharmaceutical to each examinee included in the corresponding examinee group. , And it is desirable to create an operation schedule regarding the examination for each examinee included in the examinee group. Since the amount of radionuclide necessary for the group of examinees who are the subject of the inspection schedule is reflected in the creation of the operation schedule, the time required for the production of the radionuclide and the production of the radiopharmaceutical using the radionuclide is reduced. Estimates can be made and operation schedules can be created easily. Furthermore, since the information on the examination schedule is reflected in the creation of the operation schedule, the operation schedule can be created in accordance with the examination time of the corresponding group of examinees. Since the operation schedule is created based on the above radionuclide amount and inspection schedule information, the production of radionuclides, the production of radiopharmaceuticals, the administration of radiopharmaceuticals to examinees, and the nuclei included in the examinee group It is possible to schedule a series of examination processes for a person to be examined without waste of time. This leads to an increase in the number of examinees who undergo radiation screening.

Preferably, based on the calculated radionuclide amount, the time required for the production of the radionuclide and the time required for the production of the radiopharmaceutical containing the radionuclide are determined by the treatment device, and the operation schedule by the treatment device is obtained. It is desirable to further use each information of the time required for the production of the obtained radionuclide and the time required for the production of the radiopharmaceutical for the preparation of the. Since the operation schedule is created by reflecting the time required for manufacturing the radionuclide and the time required for manufacturing the radiopharmaceutical, the time accuracy of the operation schedule can be improved.

[0016] Preferably, the operation schedule is preferably created for each group of examinees. Since the operation schedule is created for each group of examinees, it is possible to increase the number of examinees who can be inspected in the daily radiological examination that meets a plurality of operation schedules.

Preferably, it is desirable to control the radionuclide producing apparatus and the radiopharmaceutical producing apparatus installed in the medical institution based on the operation schedule. Since the radionuclide manufacturing apparatus and the radiopharmaceutical manufacturing apparatus are controlled based on the operation schedule, the radionuclide manufacturing apparatus and the radiopharmaceutical manufacturing apparatus can be easily driven, and the operating rates of these apparatuses are improved.

Preferably, the operation schedule is created by
It is desirable to be carried out by a radiation screening support company contracted by a medical institution. Since the radiation screening support company creates the operation schedule, the medical-related institution is freed from the operation schedule creation work. Therefore, medical institutions are
It is possible to concentrate on the diagnostic work of the examinee using the radionuclide that emits a proton beam.

It is preferable that the radiation screening support business operator manages the necessary raw material substances based on the operation schedule information by using the processing device. Medical-related institutions do not have to order raw materials necessary for radiation screening and do not manage their inventory, and a small number of people can carry out radiation screening.

[0020] Preferably, the radiation screening support company uses the processing device to generate an abnormality in these devices based on the signals output from the sensors respectively installed in the inspection device, the radionuclide manufacturing device and the radiopharmaceutical manufacturing device. It is desirable to monitor Since the radiation screening support business operator monitors the occurrence of abnormalities in the inspection device and both manufacturing devices using the processing device, the medical-related organization does not need to perform the monitoring work.
There is no need to secure personnel to carry out surveillance work.

The medical-related institution in the present application is a concept including a medical examination facility and "hospital" and "clinical office" defined by the Medical Law. A "hospital" is a place where a doctor or dentist conducts medical or dentistry for the public or a specified number of people, as defined by the Medical Law, and has a facility for accommodating 20 or more patients. Say. In addition, the "hospital" must be organized and operated with the main purpose of providing the convenience and convenience of scientific and appropriate medical treatment for the injured. "Clinic" is a place where a doctor or dentist conducts medical or dentistry for the public or a specified number of people, as defined by the Medical Law, and which does not have a patient accommodation facility or patient. It has a capacity of 19 or less. A medical examination facility is a facility that conducts medical examination without medical treatment.

[0022]

BEST MODE FOR CARRYING OUT THE INVENTION (Embodiment 1) Before explaining a radiation screening support method which is a preferred embodiment of the present invention, a radiation screening support system used in this embodiment will be described with reference to FIG. To do.

The radiation examination support system uses the Internet 6. The radiation screening support system has a server 11 owned by a radiation screening support company connected to the Internet 6 and a server 21 owned by a hospital (or a screening facility). An information processing device (for example, an information terminal) owned by the radiation screening support company is connected to the server 11. The information processing device includes a processing device 12 and an input device.
It has (for example, a keyboard) 14 and a display device 15.
The processing device 12 is connected to the server 11, and the input device 14 and the display device 15 are connected to the processing device 12. Storage device 1
3 is connected to the server 11 and the processing device 12. The information processing device owned by the hospital has a processing device 22, an input device 24, and a display device 23. The processing device 22 is connected to the server 21, and the input device 24 and the display device 23 are connected to the processing device 2.
Connected to 2. Although not shown, a storage device is connected to the server 21 and the processing device 22. The control device 4 of the PET system (installed in the hospital) is connected to the server 21. The RI manufacturing apparatus 1, the radiopharmaceutical synthesizing apparatus 2 and the inspection apparatus 3 which compose the PET system are also installed in the hospital. The control device 4 controls the RI manufacturing device 1, the radiopharmaceutical synthesizing device 2, and the inspection device (PET camera) 3. The radiopharmaceutical described below means a radiopharmaceutical containing a radionuclide that emits a proton beam unless otherwise specified. RI is also a radionuclide that emits a proton beam.

The information terminal 5 of the examinee and the information terminal 7 of the health insurance association are connected to the Internet 6. The server 16 owned by the device manufacturer is connected to the Internet 6.
The information processing device owned by the device manufacturer has a processing device 17, an input device 18, and a display device (not shown). The processing device 17 is connected to the server 21, and the input device 18 and its display device are connected to the processing device 17. The storage device 19 is connected to the processing device 17 and the server 21. The server 25 owned by the raw material supplier is connected to the Internet 6. The information processing device owned by the raw material supplier has a processing device 26, an input device 28, and a display device (not shown). The processing device 26 is connected to the server 25, and the input device 2
8 and its display device are connected to the processing device 26. The storage device 27 is connected to the processing device 26 and the server 25.

First, the production of RI for PET will be described. The production of this RI may be performed by proton beam irradiation, neutron irradiation, or the like. In those irradiation methods, the RI generation amount N is represented by the equation (1), where H is the intensity of a radiation source that generates a proton beam or a neutron.

N ′ = H−λN (1) where λ is the decay constant of RI. The decay constant of RI differs depending on the type of nuclide. The RI generation amount N and the RI generation rate N ′ are respectively N = (H / λ) [1-exp (−λt)] (2) N ′ = Hexp (−λt) (3) FIG. 2 shows the changes over time in the generation amount N and the generation rate N ′ of RI. As can be seen from FIG. 2, the RI generation rate is R
I High in the early stage of operation of the manufacturing equipment. That is, manufacturing a large amount of RI at one time means that the RI manufacturing amount does not increase despite the time required for the manufacturing, that is, the power amount. Further, as shown in FIG. 3, when a large amount of RI is generated at one time, stored, and used in several times, RI is attenuated at the rate of exp (−λt), so R
The longer the time from the manufacture of I to the use of RI, the greater the attenuation. Manufacturing a large amount of RI at one time is wasteful because it is attenuated by the time it is used even if it is manufactured. Therefore, to obtain the effect of reducing the waste of RI manufacturing,
RI is manufactured according to the amount used at one time,
Basically, the waiting time before administration of the radiopharmaceutical to the examinee should be shortened before use.

The amount of RI used at one time depends on the PE used at one time by medical-related institutions such as hospitals, clinics, and examination facilities.
It can be calculated from the number of inspection devices of the T system and the RI amount required at the time of the inspection, which is calculated from the weight of the examinee.

Further, in order to screen a large number of examinees, attention is paid to a process that takes the longest time in the PET diagnosis process, and the operating rate of the process is increased.

The longest process of the PET diagnosis process is the inspection by the inspection device 3. It is desired to create a medical examination schedule that can reduce the waste of RI manufacturing and increase the number of examinees who can be examined by the PET system.

The number of examinees who can carry out a radiation examination at one time is determined based on the number of inspection devices 3 installed in the hospital (or examination facility) where the PET system is installed, that is, the PET cameras 3. Depending on the type of radiopharmaceutical, the RI amount required for the examination is determined based on the weight of each examinee.
For example, in the case of fluorodeoxyglucose, 2-8M
It is necessary to administer the radiopharmaceutical fluorodeoxyglucose to the subject at a rate of Bq / kg. Therefore, the RI to be administered to the examinee, that is, the amount of ¹⁸ F, is determined based on the weight of the examinee. PET camera 3
The maximum number of examinees that can be examined at one time is determined based on the number of the examinees, and the RI amount used in one examination can be determined based on the total weight of these examinees.

When the required RI amount is determined in one examination, the RI manufacturing time t ₁ required to generate the RI amount is determined, and the radiopharmaceutical synthesis time t ₂ is determined. Furthermore, it is necessary to wait until the radiopharmaceutical administered to the examinee reaches an equilibrium state in the body. After administration of the radiopharmaceutical, a waiting time t ₃ is required. The time t ₃ is determined based on the past record and so on, for example, 1 hour. The waiting time varies depending on the type of radiopharmaceutical, but is determined for each radiopharmaceutical based on actual results. After the lapse of time t _3, the inspection using the PET camera 3 starts. The time required for the inspection is t ₄ . A tomographic image of the subject is created using the output of the radiation detector obtained in the examination. Time t ₅ required for image processing to obtain a tomographic image
Is the amount of data obtained by the radiation detector, that is, PET
It is determined by the imaging area of the person to be examined by the camera 3 for examination.
The moving time between each process is included in each process. When the inspection start time is determined, the manufacturing start time of RI can be determined by subtracting (t ₁ + t ₂ + t ₃ + t ₄ ) from the time. (t ₁ + t ₂ + t ₃
Based on + t ₄ + t ₅ ), the start time of each process can also be determined, and a series of radiation screening related to PET diagnosis can be determined. FIG. 4 shows an example of a daily examination schedule in which the sequence including the entire process is repeated. A series of sequences including a process from RI manufacturing to image processing is repeated a plurality of times. In the sequence shown in FIG. 4, each process is continuously executed without a break. By doing so, it is possible to increase the number of examinees to be examined in the radiological examination using the radionuclide that emits positrons, and reduce the waste of RI production.

A method of supporting radiation screening according to this embodiment will be described. First, the outline will be described with reference to FIG. The hospital shown in FIG. 5 is a hospital in which a PET system is installed.
Hereinafter, this hospital is referred to as a PET diagnostic hospital to distinguish it from a hospital that does not have a PET system. The PET diagnostic hospital may be a medical examination facility (PET diagnostic medical examination facility) in which a PET system is installed. PET as a person to be examined
This includes patients who have a diagnosis hospital, patients who have been introduced from a hospital (or clinic) other than the PET diagnosis hospital, and those who do not have a hospital but wish to have a medical examination for the purpose of physical examination.

The PET diagnostic hospital recruits the applicants for examination. PE
An examinee who wishes to have a T-diagnosis applies for a medical examination at a PET-diagnostic hospital according to the desired date of examination and his / her weight. A patient referred from another hospital (or clinic) may apply for a medical examination at that hospital (or clinic), and that hospital (or clinic) may apply for a PET diagnostic hospital.
The PET diagnostic hospital informs the radiation screening support provider of the name of the person to be examined, the desired date of examination, and the weight of the person to be examined by using the Internet. Radiation screening support company is PET
Create a medical examination implementation plan based on the information obtained from the diagnostic hospital,
Notify the PET diagnosis hospital of the examination implementation plan. The PET diagnostic hospital confirms with the person to be examined the examination date and time indicated in the examination implementation plan. The person to be inspected will ask "O
K ”or“ If NO, another check date / time ”answer P
To ET diagnosis hospital. Radiation screening support company is P
Based on the response from the ET diagnosis hospital, the examination execution plan is confirmed, and this is notified to the PET diagnosis hospital, and the operation plan of each device of the PET system is created. This operation plan is communicated to the PET diagnostic hospital, and the radiation screening support company obtains the consent of the PET diagnostic hospital and supports the operation and screening of the apparatus. Radiation examination (PE
T diagnosis) is executed. The examinee pays a portion of the cost required for PET diagnosis to the PET diagnosis hospital, and
The ET diagnostic hospital will send a medical insurance statement to the health insurance association to request payment of the remaining costs. The health insurance association pays the cost to the PET diagnostic hospital. Radiation screening support company is P
Receive service charge for support work from ET diagnosis hospital 2.

The radiation screening support method of this embodiment will be described in detail with reference to FIGS. 1 and 6. First, the PET diagnosis hospital recruits examinees to undergo a PET diagnosis. The examinee who desires the examination submits the PET diagnosis application form (see FIG. 7) (step 31). That is, the examinee accesses the server 21 of the PET diagnostic hospital from the information terminal 5 via the Internet 6 to obtain the PET diagnostic application form in order to receive the PET diagnostic as part of the physical examination. , Inputs predetermined information from the information terminal 5 and sends it to the server 21. Of the items listed in the application form,
It is mandatory to enter the name, weight, desired date of examination, and time of examination. For those who wish to undergo the examination, the examination items can be decided in consultation with the doctor at the PET diagnostic hospital. PE
For patients who need PET diagnosis among patients who are in the T-diagnosis hospital, the PET diagnosis hospital confirms their wishes and applies for radiation screening, ie, submits a PET diagnosis application form. For patients introduced from other hospitals (or clinics), the corresponding other hospitals (or clinics) submit a PET diagnosis application form (application for PET diagnosis) to the PET diagnosis hospital.

The PET diagnostic hospital sends information relating to the examinee (desired examination date, time and weight of the examinee, etc.) from the information processing device to the server 11 of the radiation examination support company via the Internet 6. Send (Step 3)
2). When transmitting the information related to the person to be examined, the PET diagnosis hospital creates a PET diagnosis prospective person notification (see FIG. 8) based on the PET diagnosis application using the information processing apparatus.
Specifically, information such as examination items determined by the doctor, the radiopharmaceutical to be used, and the dose of radionuclide is input through the input device 24, and these information and the information entered in the PET diagnosis application form are also input. At the same time, the PET diagnostic prospective person notice is created by the processing device 22. The PET diagnosis prospective person notification is created for each examinee and transmitted to the server 11.
The server 11 causes the storage device 13 to store the input information of each PET diagnosis prospective person notice for each examinee. The dose of radionuclide is calculated based on the weight of the examinee. Since the information on the inspection items, the name of the radiopharmaceutical used for the medical examination, and the dose of the radionuclide is entered in the notification letter for the PET diagnostic candidate, the radiation medical examination support company makes the type of the RI at the time of manufacturing the RI and the production thereof. The amount can be easily determined.

For patients introduced from other hospitals (or clinics), the corresponding other hospitals (or clinics) use the information processing device to send a PET diagnosis prospective person notice instead of the PET diagnosis application form. You may create and transmit this PET diagnosis prospective person notice to the PET diagnosis hospital using the internet 6. The PET diagnosis hospital has completed the reception and sends this PET diagnosis prospective person notice from the server 21 to the server 11.
Send to.

The processing unit 12 prepares a medical examination implementation plan for one day (step 33). The information of the PET diagnostic prospective notice stored in the storage device 13 is used to create the examination implementation plan. The processing device 12 is a storage device 13.
Using the date and time of the desired medical examination of each examinee and the information on the radiopharmaceutical to be administered stored in, the desired medical examination date and time of each medical examinee is organized for each type of radiopharmaceutical,
The organized result is displayed on the display device 15. FIG. 9 shows a display example of the organized result. In the display example of FIG. 9, the desired date and time of examination of each examinee are arranged for each examination date and for each radiopharmaceutical. In FIG. 9, the reason why each radiopharmaceutical containing a positron-emitting radionuclide is shown in three rows is because the number of PET cameras 3 installed in a PET diagnostic hospital is three. The type of RI and the type of radiopharmaceutical are not limited to those shown in FIG. The time required for inspection is determined depending on the type of radiopharmaceutical used (including nuclides that emit positrons), so that time is also displayed. FIG. 9 shows that the hatched time period is the desired examination time of the examinee. Although not shown, the name of the person to be examined corresponding to each hatching portion is described. When the hatched portion is clicked, detailed information (test item, type of radiopharmaceutical and dose of the radiopharmaceutical, etc.) regarding the diagnosis of the subject to be examined is displayed. When a screening implementation plan is created based on the desired screening time of each examinee (arranged as shown in FIG. 9), different nuclides are included between 10:00 am and 11:30 am The efficiency of the radiological examination is poor because the examination is concentrated on the examinees who have administered the radiopharmaceutical. Therefore, a screening implementation plan that improves the efficiency of radiation screening is created. This screening implementation plan is created by the processing by the processing device 12 itself and the interactive processing between the operator of the radiation screening support business operator and the processing device 12.

The memory device 13 includes a group of examinees including a number of examinees who are within the range of the number of the inspection devices 3 and who administer the same kind of radiopharmaceutical (group of examinees). ), A group of a plurality of examinees to which a different type of radiopharmaceutical is contained, which contains the same type of RI, but a group of subjects to which a single type of radiopharmaceutical is introduced. Subsequently, another group of examinees to which other types of radiopharmaceuticals will be injected will be examined, and the examination time of the examinees who will be administered a radiopharmaceutical containing a nuclide with a short half-life will be shortened. The date and time (at least the date and time) are prioritized for the examinee who requests the time and time, and the radiation for the examinee who does not give the request for the desired date and time is At the time of medical examination by the dialogue processing with the operator of the medical examination support company To determine the stores a medical examination carried out planning rule that. According to the rules, ¹⁵ O (half-life: 2 minutes), ¹³ N (half-life: 10 minutes),
¹¹ C (half-life: 20 minutes) and ¹⁸ F (half-life: 110 minutes)
In this order, the examination time of the examinee who administers the radiopharmaceutical containing the nuclide is delayed. If more than one type of radiopharmaceutical is used in a day, even if there is a subject to whom the rule applies, the rule and will take precedence when determining the examination time within the desired date of examination. Then used. Also, rules and are used in preference to rules.

In order to apply the rule, the RI amount contained in the radiopharmaceutical administered based on the weight of each examinee and the amount of the radiopharmaceutical for all examinees who are subjects of the daily radiological examination. The dose is calculated in advance by the processing device 12. For example, if the radiopharmaceutical is ¹⁸ FDG fluorodeoxyglycol, the required fluorine-18 (
The amount of ¹⁸ F) is 2-8 MBq / kg. When the radiopharmaceutical is nitrogen gas, the required amount of nitrogen 13 ( ¹³ N) is 8 to 24 MBq / kg. Therefore, it is necessary to estimate the RI amount according to the weight of each examinee.

The processing when the rule is applied will be described. If the rules apply, the processing device 12
Is a display device 15 for each examinee showing the above-mentioned RI amount and dose of the radiopharmaceutical calculated for the examinee who did not give the hope of the examination desired date and time and the examinee who gave the hope. , And at least input the examination time of the examinee who did not give the hope of the desired examination date.
The operator inputs the examination time of the examinee for the corresponding radiopharmaceutical from the input device 14. Based on the entered examination time, the examination time for the corresponding radiopharmaceutical of the person to be examined is included in the examination implementation plan guide created by applying the rule or. After that, the processing device 12 calculates the production amount of each type of RI on a monthly and daily basis based on the created screening implementation plan. These R
In order that the production amount of I can be leveled, the average production amount for each daily pro rata and monthly prosecution for each type of RI is calculated by the processing device 1
2 is calculated based on the information on the past manufacturing quantities stored in the storage device 13 and displayed on the display device 15. Since the average production amount for each type of RI is displayed on the display device 15, the operator sees the RI amount for the examinee who did not give the hope of the desired date of examination, and further calculates the past monthly installment and daily installment. It is possible to easily determine the examination time of the examinee so that the RI production amount can be leveled in consideration of the average production amount.

By "accelerating the examination time of the examinee who administers the radiopharmaceutical containing a nuclide having a short half-life",
An RI having a short half-life can be manufactured first to synthesize a radiopharmaceutical containing the RI. Therefore, when synthesizing a radiopharmaceutical containing a long half-life RI, even if the short half-life RI remains in the radiopharmaceutical synthesizing device 2, the short half-life RI decays quickly, and thus the long half-life RI. The influence on the examination of the examinee who has been administered the radiopharmaceutical including is reduced. In particular, when one examinee performs an examination on the same day with different radiopharmaceuticals containing different types of RI, that is, when cross-checking for abnormalities in the examinee, radioactivity containing a nuclide with a short half-life is used. Performing the test by administering the drug first has less effect on the test administering the radiopharmaceutical including RI having a long half-life, and the accuracy of the latter test is also good.

By carrying out the processing described above, for example, a medical examination implementation plan for each day shown in FIG. 10 is created. This examination implementation plan is stored in the storage device 13.
The medical examination implementation plan shown in FIG. 9 in which the desired medical examination date and time of each person to be examined are arranged is recreated into the medical examination implementation plan shown in FIG. The examination implementation plan of FIG. 10 eliminates the concentration of examination time for examinees who have administered different types of radiopharmaceuticals at specific times. With such a medical examination implementation plan, the operation rate of each device can be improved without causing any trouble in the operation of each device of the PET system.

The creation of the medical examination implementation plan shown in FIG. 10 will be specifically described. As mentioned above, the PET diagnostic hospital is P
Three ET cameras 3 are installed. Since one PET camera can inspect one examinee, it is possible to inspect up to three examinees at one time. The radiation screening support company creates a screening implementation plan by the processing device 12 using the information described in the PET diagnosis application form and the PET diagnosis prospective person notification form transmitted from the PET hospital. First of all, for those who wish to have a medical examination on a certain date,
By applying the rule, the processing device 12 selects a person to be examined to whom the same type of radiopharmaceutical is administered based on the information of “radiopharmaceutical” described in the PET diagnosis prospective notice. As a result, as shown in FIG. 10, three examinees to which ¹⁵ O ₂ was administered, three examinees to which ¹³ N ₂ was administered, ¹⁸ F
6 examinees receiving DG fluorodeoxyglucose, 6 examinees receiving fluorodopa,
Each is selected. Some radiopharmaceuticals are administered to only one or two examinees. Due to the number of the inspection devices 3 installed, only a maximum of 3 persons can be inspected at one time, so that 3 persons to be inspected for each radiopharmaceutical of the same type form one group of persons to be inspected. 1 for each radiopharmaceutical with less than 3 and only 1 or 2 examinees
One group of examinees is formed. The processing device 12 then applies the rule to the group of examinees who receive the radiopharmaceutical including the same type of RI, following the examination of the group of examinees to whom one type of radiopharmaceutical is administered. The examination of a group of examinees to which another type of radiopharmaceutical is administered should be performed. That is, both ¹⁸ FDG fluorodeoxyglucose and fluorodopa are RIs of the same type.
^{Since 18} F is included, the examination plan is prepared so that the examination of the group of examinees to which fluorodopa is administered is performed subsequent to the examination of the group of examinees to which ¹⁸ FDG fluorodeoxyglucose is administered. It The processing device 12 applies the rules to arrange the selected groups of examinees in the order of shorter half-life of RI contained in the administered radiopharmaceutical. Regarding the application of the rules, all the examinees are satisfied with the desired date. For the desired time,
It has been changed in some examinees. Processing device 12 described above
By the processing using, the examination time by the examination device 3 is determined for each group of examinees, and the examination implementation plan shown in FIG. 10 is created. This examination implementation plan is an examination schedule.

The radiation examination support company sends the examination implementation plan draft from the server 11 to the server 21 via the Internet 6 in order to obtain the approval of the PET diagnostic hospital for the created examination implementation plan (step 34). When sending this, in order to inform the examinee of the examination date,
Moreover, in order to obtain consent for the changed examination date (or time) for the examinee whose examination date (or time) is different from the desired examination date (or time), FIG.
A notification form for the scheduled PET examination date is also sent to the PET diagnostic hospital via the Internet 6. PET
The diagnostic hospital sends the received notice to the relevant examinee. The notification form may be sent directly to the person to be examined by the radiation examination support company. The examinee whose medical examination date has been changed can enter a convenient medical examination date (or time) in the notification form in FIG. 11 when the changed medical examination date (or time) is inconvenient and the PET diagnostic hospital (Or a radiation screening support company). If there is any inconvenience in other items, the examinee fills in the wishes for the location and sends a reply. The PET diagnostic hospital sends the notice of FIG. 11 sent from the person to be examined to the server 11 of the radiation examination support company via the Internet 6. It is advisable to inform the examinees whose examination dates (or hours) have been changed so that the examination dates (or times) can be adjusted early so that the radiation examination date and time are available. For information on the date and time when there is a space for radiation screening,
It is posted on the website of radiation screening support companies.
The PET diagnostic hospital can know the date and time when there is a vacancy in the radiation examination by accessing the homepage from the information processing device of the PET diagnostic hospital when applying for the examination, and the vacant date Also, you can apply for medical examination at the time.

Next, the processing unit 12 carries out the processing of confirming the medical examination implementation plan (step 35). That is, the processing device 12 determines whether or not there is a change request in the response of each examinee transmitted from the PET diagnostic hospital, and if there is a change request, reflects the information of the changed portion and proposes a medical examination implementation plan. To change. For example, when it is requested to change the examination date (or time), the examination execution plan reflecting the changed examination date (or time) is created and registered in the storage device 13. When it is determined that there is no change request, the processing device 12 registers the examination execution plan draft created in step 33 in the storage device 13 as the examination execution plan. Since there was no change request for the examination implementation plan shown in FIG. 10, the examination implementation plan is registered as the examination implementation plan. This confirmed examination implementation plan is an examination schedule in which the examination time for each examinee is specified. The hatched time period in FIG. 10 is the examination time of the examinee. Figure 10
Also, in the same manner as in the case of FIG. 9, the name of the subject to be examined is described in each hatched portion, and detailed information regarding the diagnosis of the subject to be examined is displayed by clicking the hatched portion.

In this example, the test using the RI having a short half-life is performed first. However, the test using the radiopharmaceutical containing the same RI throughout the day is performed by changing the date according to the type of RI. It is also possible to plan to do so.

The processing device 12 uses the information of the confirmed medical examination execution plan registered in the storage device 13 as the PET.
A system operation plan is created (step 36). That is, the processing device 12 starts the operation start time and the operation end of each device (RI manufacturing device 1, radiopharmaceutical synthesizing device 2, and PET camera 3) constituting the PET system based on the information of the confirmed medical examination implementation plan. Determine the time. To determine the operation start time and the operation end time, the RI manufacturing time t ₁ , the radiopharmaceutical synthesis time t ₂ , the waiting time t ₃ , and the time t ₄ required for the inspection by the PET camera 3 are determined. Also, the time t ₅ required for image processing is required. RI manufacturing time t ₁ , radiopharmaceutical synthesis time t ₂ , P
The inspection time t ₄ using the ET camera 3 and the time t ₅ required for image processing are obtained by the processing device 12. That is, the processing device 12 calculates the corresponding RI amount required for one examination based on the total weight of all the examinees included in the examinee group corresponding to each examinee group, and the RI amount is calculated. The RI manufacturing time t ₁ required for manufacturing the is calculated. Since the radiopharmaceutical used for each group of examinees is decided,
The required RI in the group of examinees is specified. The processing device 12 calculates the synthesis time t ₂ of the corresponding radiopharmaceutical containing the RI based on the calculated RI amount. The processing device 12 calculates the time t ₄ which is the imaging time by the PET camera 3 based on the site of diagnosis of the inspection item. Also,
The processing device 12 estimates the amount of data obtained by the PET camera 3 and calculates the time t ₅ . By using these times and the examination start time shown in the examination implementation plan, the operation start time and operation end time of each of the above-mentioned devices, and further the image processing start time are obtained. The information on the operation plan of the PET system created in this way is stored in the storage device 13.
The information on the operation plan of the PET system also includes information on the RI amount calculated for the group of examinees.

12 and 13 show examples of the operation plan created in step 36. FIG. 12 shows the RI manufacturing apparatus 1, the radiopharmaceutical synthesizing apparatus 2, the radiopharmaceutical administration and waiting time, the examination, and the image processing when the radiopharmaceuticals ¹⁵ O ₂ and H ¹⁵ O ₂ shown in FIG. Indicates the time zone.
In the example in which the inspection time is the longest, the start time of each device is determined so that all the PET cameras 3 can be operated to perform the inspection. In the operation plan of FIG. 12, ¹⁵ O which is RI is manufactured by one RI manufacturing device 1, synthesized by one radiopharmaceutical synthesizing device 2, and at the same time, the radiopharmaceutical is administered to three examinees. This is an example in which inspection is performed by one PET camera 3 and image processing is performed by one computer (image processing device). FIG.
Shows an operation plan in the case of conducting an inspection using fluorodeoxyglucose and fluorodopa shown in FIG. 10 as radiopharmaceuticals. Fluorodeoxyglucose and fluorodopa use fluorine 18 with a half-life of 110 minutes. RI is of the same type, but at the time of synthesis it changes the drug source to produce a different radiopharmaceutical. The operation plan of the PET system is created for each date and for each radiopharmaceutical. Other radiopharmaceuticals shown in FIG. 10 ( ¹³ N ₂ and ¹¹ C, etc.)
For the above, the operation plan of the PET system is similarly created. The operation plan of the PET system created for each radiopharmaceutical corresponds to the parallel operation plan shown in FIG.

Information on the operation plan of the created PET system
The information is sent from the processing device 12 via the Internet 6.
It is sent to the address 21 (step 37). Server 21
Outputs this information to the controller 4 and is not shown
Store in the storage device. The processing device 22 is a PET system.
The display unit 23 displays the information on the operation plan of the system. Control equipment
Table 4 shows the operation plan of the PET system on the relevant date.
RI manufacturing device 1, radiopharmaceutical synthesis device based on information
It controls two and three PET cameras 3. That is,
Controller 4 was set in the operation plan of the PET system
Activate those devices in time and deactivate them
It The RI manufacturing apparatus 1 is an ion beam emitted from the accelerator.
Irradiate the target material with the target to produce the corresponding RI.
It Target material depends on the type of RI manufactured
Is different. RI manufacturing equipment before the necessary RI manufacturing starts
The target material corresponding to 1 is installed. Radiopharmaceutical
Also in the synthesizer 2, a labeling substance necessary before the start of drug synthesis
Quality is prepared for availability. Such an RI manufacturing apparatus 1
And preparatory work before starting the operation of the radiopharmaceutical synthesizer 2
Industry, and the operation of these devices
Will be implemented. The control device 4 is the RI manufacturing in the operation plan.
When the operation start time of the apparatus 1 is reached, the RI manufacturing apparatus 1 is
Activate and apply the appropriate RI (eg¹⁵O) is produced. Control
The control device 4 stops the RI manufacturing device 1 at the operation end time.
It The RI manufacturing apparatus 1 manufactures a required amount of RI. Control equipment
Position 4 is the time when the radiopharmaceutical synthesizer 2 starts operating.
At this time, the radiopharmaceutical synthesizing device 2 is activated. Radiopharmaceutical
The synthesizer 2 uses the manufactured RI (for example, ¹⁵O)
Radiopharmaceutical required by synthesizing a labeling substance (¹⁵O
₂ ) Is manufactured. When the operation end time is reached, the control device
4 stops the operation of the radiopharmaceutical synthesizing device 2. A certain amount
After the radiopharmaceutical is manufactured, the time of drug administration in the operating plan
When it comes to radiopharmaceuticals, employees of PET diagnostic hospital
Administered by 3 patients (eg nurses)
It The inspection starts after a lapse of a predetermined waiting time. before that
Each examinee is PET certified by an employee of the PET diagnostic hospital.
Can be laid on the bed of the camera 3 for use. PET camera 3
When the operating time of is reached, the control device 4 displays the PET camera.
The display device installed on the operation panel of No. 3 has the PET camera 3
Display operation start information. This operation start display is
It is displayed on the display device of the PET camera 3. That's it
Each operator attached to the PET camera 3 is
It is in a state where it is possible to check the condition of the examinee on the tablet and take pictures
At this time, the operation switch of the PET camera 3 is turned on.
A plurality of radiation detectors installed in the PET camera 3
Due to the RI contained in the radiopharmaceutical, is it the body of the examinee?
Γ-rays emitted from the sensor are detected. The inspection of the prescribed area is completed
The operator stops the operation of the PET camera 3 when
It Enter the γ-ray data measured by each radiation detector
The computer that uses the data
Create a tomographic image of the part.

The PET diagnosis hospital diagnoses the relevant portion based on the obtained tomographic image and informs the examinee of the result of this diagnosis. The tomographic image data of the person to be examined introduced from another hospital (or clinic) is transmitted to the other hospital (or clinic) via the Internet 6 together with the diagnosis result.

According to this embodiment, the radiation screening support company obtains information about the name of the person to be examined, the weight of the person to be examined, and the type of radiopharmaceutical (or RI) used for PET diagnosis, and uses it. Since an inspection schedule in which the inspection time for each examinee is specified is created for each RI and an operation plan of the PET system is created based on this inspection schedule, the PET diagnostic hospital does not need to perform such complicated operations. Therefore, the burden on the PET diagnostic hospital regarding the operation of the PET system can be reduced. In particular, a medical examination in which the same type of radiopharmaceutical (or the same type of RI) is administered within the range of the maximum number of medical examinees that can be inspected at once considering the number of inspection devices 3 installed in the PET diagnostic hospital. Since a group of persons is constructed and an examination schedule is created by allocating examination time to each group of examinees, R
The I manufacturing apparatus 1, the radiopharmaceutical synthesizing apparatus 2, and the inspection apparatus 3 can be operated smoothly, and as a result, the number of examinees who can be inspected per day can be increased. When the examinee who has administered different types of radiopharmaceuticals are examined by the three examination devices 3, different types of RIs and radiopharmaceuticals are determined by the RI manufacturing device 1 and the radiopharmaceutical synthesis device 2 which are the pre-stages of the examination. Need to be manufactured respectively. R
Since there is only one production apparatus 1 and radiopharmaceutical synthesis apparatus 2, it is necessary to replace the target substance as a raw material of RI and the labeling substance necessary for the radiopharmaceutical, and to manufacture different types of RI and radiopharmaceutical respectively. Takes a long time. In this embodiment, since the examination time is assigned to each group of examinees including a plurality of examinees to which the same radiopharmaceutical is administered, as is clear from the operation plans of the PET system shown in FIGS. The time required for the RI and the radiopharmaceutical required for one examination by the manufacturing apparatus 1 and the radiopharmaceutical synthesizing apparatus 2 is shortened. When an examination schedule is created for a group of examinees as in this example, the raw materials supplied to the RI manufacturing apparatus 1 and the radiopharmaceutical synthesizing apparatus 2 even if one inspection apparatus 3 is added later. All you have to do is increase the amount of substance.

Furthermore, since the examination schedule is created by grouping the examinees who use the same type of radiopharmaceutical,
The PET system can be operated smoothly, and 1
The number of people to be examined for PET diagnosis per day can be increased. In particular, since a test for a subject who administers a radiopharmaceutical containing a RI having a short half-life is performed at an early time of the day, a subject to be examined who administers a radiopharmaceutical containing a RI having a long half-life to be performed later. Does not affect the inspection of.

According to this embodiment, since RI is manufactured for each group of examinees, RI can be manufactured in a portion where the amount of RI manufactured is small and the RI generation rate is high as shown in FIG. Therefore, RI
The power consumption of the manufacturing apparatus 1 can be reduced.

According to this embodiment, the PET diagnostic hospital can obtain the following effects.

(1) Since the examinees are examined based on the examination implementation plan, the number of examinees who carry out the examination can be increased.

(2) By the operation based on the operation plan of the PET system, it is possible to reduce the power consumption, to effectively use the assets by improving the operating rate by eliminating the waste of the used raw materials, and to efficiently use the equipment.

For a radiation screening support company, a new support work as in this embodiment can be performed.

(Embodiment 2) A radiation screening support method which is another embodiment of the present invention will be described with reference to FIG. The system shown in FIG. 1 is also used in this embodiment, and the information processing apparatuses owned by the radiation screening support company, PET diagnostic hospital, equipment manufacturer and raw material supplier are connected via the Internet 6 as shown in FIG. There is. Also in this embodiment, steps 31 to 37 shown in FIG. 6 described in the first embodiment are performed.
The process of is executed. The radiation screening support company uses the created PET system operation plan information P as in the first embodiment.
Contact the ET diagnosis hospital. Radiation screening support company is PE
With the consent of the T-diagnosis hospital, as in the first embodiment, the operation of the device and the medical examination are supported. Also in this embodiment, the first embodiment
The examination is performed on the examinee in the same manner as. The radiological examination support business requires each target substance used for RI production and each labeled substance used for production of radiopharmaceuticals, which is required for each day based on the created examination schedule (for example, the examination implementation plan shown in FIG. 10). The amount of raw materials such as Further, since the radiation screening support company performs the preparatory work (described in the above-mentioned embodiment) on the RI manufacturing apparatus 1 and the radiopharmaceutical synthesizing apparatus 2 of the PET system installed in the PET diagnostic hospital before starting the operation. , You can also understand how much of those raw materials actually remain.
The radiation screening support company manages the stock of raw materials at the request of the PET diagnostic hospital. The inventory management table shown in FIG. 15 is used for this inventory management. This inventory management table is stored in the storage device 13. Radiation screening support companies
The storage device 13 is operated by operating the processing device 12 from the input device 14.
The corresponding inventory control table is read out and displayed on the display device 15. The radiation screening support company inputs the amounts of the target substance and the labeling substance, etc. used by the production of RI and the synthesis of the radiopharmaceutical from the input device 14, and the display device 1
Enter the amount used in the prescribed column of the inventory control table displayed in 5. The radiation screening support company manages the device loading amount of the raw material, the remaining amount in the device, the inventory amount, the planned ordering amount, etc. using the inventory management table. Based on this, the radiation screening support business operator makes a raw material purchase plan and stores the raw material purchase plan in the storage device 13. Based on the prepared raw material purchase plan, the radiation screening support company places an order for the corresponding raw material substance in advance using the information processing device including the processing device 12. Information on the raw material substance to be ordered, the order quantity, and the delivery deadline is transmitted to the server 25 of the raw material supplier via the server 11 and the Internet 6, and stored in the storage device 27. The raw material supplier sends a response indicating that the order has been accepted to the server 11 via the Internet 6. The raw material supplier delivers the ordered raw material by the deadline to the radiation screening support operator. The radiation screening support company pays the raw material supplier a price for purchasing the raw material. The radiation screening support company charges the price to the PET diagnostic hospital.

The radiation screening support company receives a request for monitoring and maintenance of the PET system from the PET diagnostic hospital. That is, the radiation screening support company manages utilities such as gas, water, and electric power, manages equipment, and supports operation of facilities. The radiation screening support company incorporates a monitoring program for monitoring the PET system into the information processing apparatus of the radiation screening support company including the processing device 12. The information processing apparatus is the RI manufacturing apparatus 1 of the PET system.
The radiopharmaceutical synthesizing device 2, the PET camera 3, and the electric power system of the computer that is the image processing device, the sensors installed in the signal system, the sensors installed in the air conditioning system, the thermometer, and the measured values by the radiation monitor are measured on the Internet 6. It is taken in through, and these measured values are processed by a monitoring program to determine whether there is any abnormality. The determination result of the presence / absence of these abnormalities is obtained by the processing device 12 as “PET
The system diagnostic result entry table "is entered. This "PE
The T system diagnosis result entry table ”is stored in the storage device 13. The radiation monitor monitors the leakage of radiation.
Although not shown in FIG. 16, the RI manufacturing apparatus 1 monitors, for example, the usage amount of electric power, the temperature status of each part, the radiation leakage status, and the equipment status. Regarding the radiopharmaceutical synthesizing device 2, for example, the states of the amount of electric power used, the temperature of each part, the state of radiation leakage, the state of flow rate of raw materials, medicines and the like are monitored. The PET camera 3 monitors, for example, the usage amount of electric power, the temperature status of each part, the radiation leakage status, the signal system status, and the status of each sensor. The image processing device monitors, for example, the power usage status, the temperature status of each part, the signal system status, the calculation processing status, and the disk capacity status. The radiation examination support company formulates a maintenance inspection plan for the PET system based on the information entered in the "PET system diagnostic result entry table". When maintenance / inspection is required for the PET system, the radiation screening support company transmits maintenance / inspection request information from the information processing device to the server 16 of the device manufacturer via the server 11 and the Internet 6. This request information is transmitted to the server 21 of the PET diagnosis hospital, and notifies the PET diagnosis hospital of the maintenance and inspection of the PET system. Equipment manufacturer is PET
Carry out maintenance and inspection of the PET system installed in the diagnostic hospital. After the completion of the maintenance and inspection, the radiation screening support company pays the maintenance and inspection fee to the device manufacturer and bills the fee to the PET diagnostic hospital.

This embodiment also produces the effects obtained in the first embodiment. Further, this embodiment is a PET system operation support,
Since the monitoring and maintenance / inspection of the PET system are requested to the radiation screening support business, the radiation screening support business can provide the PET diagnostic hospital with a service for performing remote monitoring and performing office work management in accordance with the commissioned work. PET diagnostic hospital is P
Since the management work for monitoring and maintenance of the ET system is outsourced to the radiation screening support business, it is not necessary to carry out such work, and the burden on the PET diagnostic hospital is reduced. PE
Accidents can be prevented by monitoring the T system, and PE by performing maintenance and inspection.
The T system can be operated efficiently.

(Embodiment 3) A radiation screening support method which is another embodiment of the present invention will be described with reference to FIGS. 1 and 17. The information processing devices owned by the radiation screening support company, the PET diagnostic hospital, the equipment manufacturer and the raw material supplier are connected via the Internet 6 as shown in FIG.
In the present embodiment, the processing performed in the second embodiment (including the processing in the first embodiment) is also executed. In this embodiment, the radiation screening support company provides information on new products and new raw materials, and
ET Diagnostic Hospital 2 The inspection function will be expanded to support the administrative procedures for equipment updates.

The radiation screening support company is a P
Information on new products relating to the RI manufacturing apparatus 1, radiopharmaceutical synthesizing apparatus 2 and PET camera 3 constituting the ET system, new material information relating to the raw materials used in the PET system from the raw material supplier, via the Internet 6. The information is acquired and the information is provided to the PET diagnostic hospital via the Internet 6. "Via Internet 6"
The expression of means transmission of information using the radiation screening support system shown in FIG. The radiation screening support company considers the update of the corresponding device based on the information of each device obtained by the monitoring of the PET system executed in the second embodiment, and proposes the update of the device to the PET diagnostic hospital. . Upon receiving a request for purchasing a device from the PET diagnostic hospital, the radiation screening support company places an order for a new product related to the device to the device maker via the Internet 6. The equipment manufacturer delivers the ordered equipment to the PET diagnostic hospital and reports it to the radiation screening support company. The radiation screening support company pays the equipment manufacturer for the delivery of the device. Radiation screening support companies use the price for PET
Bill the diagnostic hospital.

Further, the radiation screening support company considers the type of radiopharmaceutical and the update of new raw materials accompanying this, based on the information obtained by the change of the inspection item and the PET system monitoring,
Suggest to PET diagnostic hospital. Radiation screening support companies are PE
When a request for purchasing a new raw material is received from the T-diagnosis hospital, an order for the new raw material is placed to the raw material supplier via the Internet 6 using the information processing device. Raw material supplier is PE
The new raw material ordered is delivered to the T-diagnosis hospital, and the radiation screening support company pays the price to the raw material supplier and bills the price to the PET diagnostic hospital.

As described above, the radiation screening support company provides the PET diagnostic hospital with a service for providing information on new products, new raw materials, etc., and providing administrative services to the PET diagnostic hospital. The burden on the operation of can be reduced. In particular, the PET diagnosis hospital does not need to order the raw materials necessary for the radiation screening and manage the inventory thereof, and can carry out the radiation screening with a small number of people. The present embodiment can obtain the effect produced in the second embodiment.

(Embodiment 4) A radiation screening support method which is another embodiment of the present invention will be described with reference to FIG. The information processing devices owned by the radiation screening support company, the PET diagnostic hospital, the examinee, and the health insurance association are connected via the Internet 6 as shown in FIG.

The radiation screening support company, in consultation with the PET diagnostic hospital, provides medical information, information on the effectiveness of the screening, P
We undertake the work of disclosing PET diagnosis information and screening schedules of ET diagnosis hospitals. Radiation screening support companies provide homepages to general citizens who are doing health checkups at public institutions, people over a certain age who do not have the opportunity to check up at work, etc.
The information is made public using the Internet 6.
Those who wish to have a PET diagnosis (examined person) by looking at the published information can use the Internet 6 (or other contact means such as telephone and FAX) to make a PET diagnosis hospital (or a radiation examination support). Apply for a medical examination to a vendor.
The examinee submits the PET diagnosis application form (FIG. 7) in which predetermined items are entered to the PET diagnosis hospital, as in the first embodiment. The PET diagnostic hospital that has received the application transmits the information related to the person to be examined to the server 11 of the radiation examination support company via the Internet 6 as in the first embodiment. Processing and operations performed by the radiation screening support company, and further PE
The PET diagnosis performed in the T-diagnosis hospital is the same as that in the first embodiment, and thus the description thereof is omitted here. The fourth embodiment can also obtain the same effect as the first embodiment.

(Embodiment 5) The aforementioned information processing apparatus (processing device 12 and storage device 13 owned by a radiation screening support company
Etc.), a schedule management program necessary for operating the PET system is incorporated.
This schedule management program is stored in the storage device 13. The schedule management program is the first embodiment.
It has a function of creating the medical examination implementation plan and the operation plan of the PET system based on the medical examination implementation plan described above. This schedule management program can be accessed from the homepage provided on the site of the server 11 of the radiation screening support company. The PET diagnostic hospital can use the schedule management program by accessing the home page from the processing device 22 via the Internet 6 using the input device 24. That is, the PET diagnosis hospital can create the examination implementation plan and the operation plan of the PET system described in the first embodiment by giving the necessary information to the schedule management program, and can obtain the information related to the created plans. . The PET diagnostic hospital pays the usage fee for the schedule management program to the radiation screening support company. The PET diagnostic hospital carries out a PET examination on the examinee based on the obtained examination implementation plan and the operation plan of the PET system. The maintenance management function of the PET system described in the second embodiment and the third embodiment in the schedule management program.
By adding the function of providing the information providing service such as the new product and the new raw material described above, the burden of performing each of the above work in the PET diagnosis hospital can be further reduced.

In each of the embodiments described above, the PET system (RI manufacturing apparatus 1, radiopharmaceutical synthesis apparatus 2 and PET
I explained that the camera 3) was installed in the PET diagnostic hospital, but the PET system is owned by the PET diagnostic hospital. However, even when the PET system is rented or leased and installed in the PET diagnostic hospital, each of the above-described embodiments is applicable. RI of PET system
Even when the manufacturing apparatus 1 or the RI manufacturing apparatus 1 and the radiopharmaceutical synthesizing apparatus 2 are installed in the PET diagnostic hospital by rental or lease, the above-described respective embodiments can be applied.

Each of the embodiments described above is also applicable to the case where the PET system is installed in the clinic or the examination facility and the clinic or the examination facility makes the PET diagnosis.

In each of the above-described embodiments, the explanation has been made as an example of supporting the operation, management and maintenance of the PET system which is the work performed by the PET diagnostic hospital. However, all the operation, management and maintenance related to the PET system are conducted by the radiation screening business. Person (PET
The PET diagnosis hospital is responsible for managing the doctors, radiological technologists, nurses, pharmacists, etc. involved in the land, building, and examination / diagnosis activities. Responsible for radiation screening business and PE
It may be possible to carry out jointly with a T-diagnosis hospital. As a result, the PET diagnostic hospital can fully utilize its medical expertise to perform high-quality examination and diagnosis, which in turn can increase the number of examinees. Radiation screening operators who provide services such as operation, management and maintenance are
It is possible to efficiently operate the PET system by making full use of the maintenance technology.

This embodiment relating to the PET system described above can also be applied to an inspection performed using a SPECT system, an X-ray CT system or the like.

[0072]

According to the present invention, it is possible to reduce the burden on the operation of radiation screening and increase the number of examinees.

[Brief description of drawings]

FIG. 1 is a configuration diagram of a radiation screening support system to which a radiation screening support method according to an embodiment of the present invention is applied.

FIG. 2 is a characteristic diagram showing a temporal change in the production amount of a radionuclide and its production rate.

FIG. 3 is an explanatory diagram showing how the RI amount is attenuated when RI is used.

FIG. 4 is an explanatory diagram showing a method of operating a PET system for a PET diagnosis process.

5 is an explanatory diagram showing the exchange of information between businesses in the radiation screening support method that is an embodiment of the present invention using the radiation screening support system of FIG. 1. FIG.

FIG. 6 is an explanatory diagram mainly showing processing performed by the processing device 12 shown in FIG. 1.

FIG. 7 is an explanatory diagram showing an example of an input screen for a PET diagnostic application form.

FIG. 8 is an explanatory diagram of a PET diagnosis prospective person notice.

FIG. 9 is an explanatory diagram showing a medical examination implementation plan created by organizing desired medical examination dates and desired times of respective examinees.

FIG. 10 is an explanatory diagram showing a confirmed medical examination implementation plan.

FIG. 11 is an explanatory diagram of a PET screening scheduled date notice.

FIG. 12 is an explanatory diagram showing an example of an operation plan of the PET system when an inspection is performed using a certain radiopharmaceutical.

FIG. 13 is an explanatory diagram showing an example of an operation plan of the PET system when an inspection is performed using another radiopharmaceutical.

FIG. 14 is an explanatory diagram showing an outline of a radiation screening support method according to another embodiment of the present invention, and mainly showing a flow of information and cost in the embodiment.

FIG. 15 is an explanatory diagram showing an example of an inventory management table used in the embodiment of FIG.

16 is an explanatory diagram showing an example of a diagnostic result entry table of the PET system used in the embodiment of FIG.

FIG. 17 is an explanatory diagram showing an outline of a radiation screening support method according to another embodiment of the present invention, and mainly showing a flow of information and cost in the embodiment.

FIG. 18 is an explanatory diagram showing an outline of a radiation screening support method according to another embodiment of the present invention, and mainly showing a flow of information and cost in the embodiment.

[Explanation of symbols]

DESCRIPTION OF SYMBOLS 1 ... RI manufacturing apparatus, 2 ... Radiopharmaceutical synthesis apparatus, 3 ... Examination apparatus (PET camera), 4 ... Control apparatus, 5, 7 ... Information terminal, 6 ... Internet, 11, 16, 21, 25 ... Server, 12 , 17, 22, 26 ... Processor, 13, 1
9, 27 ... Storage device, 14, 18, 24, 28 ... Input device, 15, 23 ... Display device.

Continued front page    (72) Inventor Akira Uemura             4-6 Kanda Surugadai, Chiyoda-ku, Tokyo             Within Hitachi, Ltd. F term (reference) 2G088 EE01 EE02 FF07 KK20 KK24                       KK40

Claims (14)

[Claims] 1. A number of inspection devices installed in a medical institution for detecting γ-rays emitted by a radionuclide from a subject who has been administered a radiopharmaceutical containing a radionuclide that emits a proton beam. Within the range of, the examinee to be examined at one time is selected by the information processing device using the information of the radiopharmaceutical administered to the examinee, and the selected examinee to be examined at one time is A method of assisting radiation screening, comprising a group of examinees, setting an examination time by the examination device for each group of the examinees, and creating an examination schedule for the examinees by the processing device. 2. The selection of the person to be examined included in the group of persons to be examined is made by selecting the person to be examined to administer the same kind of the radiopharmaceutical by the processing device. Support method for radiation screening in Japan. 3. A group of examinees to which a certain type of the radiopharmaceutical is administered to each group of the examinees to which the different types of radiopharmaceuticals containing the same type of radionuclide are administered. The radiological examination support method according to claim 2, wherein the examination schedule is created so as to perform the examination of another group of examinees to whom another type of the radiopharmaceutical is administered subsequent to the examination. 4. The method according to claim 1, wherein the examination time is set for each group of examinees according to the half-life of the radionuclide contained in the radiopharmaceutical. 5. The method according to claim 4, wherein the examination time is set to an earlier time zone for the group of examinees to whom the radiopharmaceutical including the radionuclide having a short half-life is administered. 6. The number of inspection devices installed in medical institutions for detecting γ-rays emitted from a radionuclide from a subject who has been administered a radiopharmaceutical containing a radionuclide that emits a proton beam. Within the range of, the examinee to be examined at one time is selected by the information processing device using the information of the radionuclide to be administered to the examinee, and the selected examinee to be examined at one time is selected. A method for assisting radiation screening, comprising: one group of examinees, setting an examination time by the examination device for each group of the examinees, and creating an examination schedule for the examinees by the processing device. 7. The radiation screening support method according to claim 1, wherein the inspection schedule is created by a radiation screening support business operator requested by the medical-related organization. 8. Based on the total weight of the examinees included in the group of examinees, the corresponding radionuclide necessary for the examination of all examinees included in the group of examinees by the processing device. Calculate the amount, based on the amount of this radionuclide and the information of the inspection schedule, by the processing device,
Production of the radionuclide, production of the radiopharmaceutical, administration of this radiopharmaceutical to each subject to be examined included in the subject group to be examined, and operation related to examination for each subject to be examined included in the subject group to be examined Claim 1 which creates a schedule
8. The method for supporting radiation screening according to any one of 7 to 7. 9. Based on the calculated radionuclide amount,
The time required for the production of the radionuclide, and the time required for the production of the radiopharmaceutical containing the radionuclide is determined by the processing device, in the production of the operation schedule by the processing device, in the production of the obtained radionuclide The radiological examination support method according to claim 8, further using each piece of information on the time required and the time required to manufacture the radiopharmaceutical. 10. The method for supporting radiation screening according to claim 8, wherein the operation schedule is created for each group of patients to be examined. 11. The radiological examination support method according to claim 8, wherein the radionuclide producing apparatus and the radiopharmaceutical producing apparatus installed in the medical institution are controlled based on the operation schedule. 12. The radiation screening support method according to claim 8, wherein the operation schedule is created by the radiation screening support business contracted by the medical institution. 13. The radiation screening support method according to claim 8, wherein the radiation screening support business operator manages necessary raw materials based on the information of the operation schedule by using the processing device. 14. The radiation screening support business employs a processing device to detect abnormalities of the inspection device, the radionuclide manufacturing device, and the radiopharmaceutical manufacturing device based on signals output from sensors respectively installed in the radiopharmaceutical manufacturing device. The method for supporting radiation screening according to claim 11, wherein the occurrence is monitored.