JP2003003013A - Oil-in-water emulsifier composition composed of alkylated polysaccharide and cosmetic using the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain an oil-in-water emulsifier composition in which an alkylated polysaccharide is used and which has high environmental compatibility, biosafety and good stability and to provide a preparation for external use for skin, a cosmetic and a hair cosmetic using the same. SOLUTION: A polyglycerol fatty acid ester is used jointly with an alkylated polysaccharide to attain the purpose.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to an oil-in-water emulsifier composition having high environmental compatibility and biosafety, which is obtained by using a polymeric emulsifier composition comprising an alkylated polysaccharide, and external preparations for skin and cosmetics using the same. And cosmetics for hair.

[0002]

2. Description of the Related Art Various surfactants are used in order to sufficiently exert the effects and effects desired as a function for external preparations for skin and cosmetics, and further exhibit a good feeling in use, and to guarantee product stability. It has been used as an emulsifier. Usually, as a surfactant used as an emulsifier in these preparations, a surfactant having a polyoxyethylene group as a hydrophilic group is mainly used, and a phase inversion emulsification method or a high-grade emulsion using a sorbitan fatty acid ester and a polyoxyethylene sorbitan fatty acid ester is used. Formulations have been prepared by an emulsion method using a liquid crystal formed from a lipophilic amphipathic substance such as alcohol and fatty acid monoglyceride and polyoxyethylene alkyl ether, or polyoxyethylene fatty acid ester.

[0003]

However, since attention has been paid to the safety and low irritation of skin external preparations and cosmetics to the skin, and from the viewpoint of environmental compatibility,
Highly compatible with living organisms and the environment, and as small as possible,
There is a need for an emulsifier that enables a preferred emulsification. Furthermore, the development of emulsification technology that does not use a surfactant has been activated. In particular, there is a demand for the development of "depolyoxyethylene-based emulsifiers" because of concerns about the safety of by-products with respect to polyoxyethylene-based emulsifiers and deactivation of active ingredients.

In order to solve these problems, an emulsifier and an emulsification method mainly containing a water-soluble polymer have been proposed. For example, synthetic water-soluble polymers such as polyvinyl alcohol, polyacrylic acid salts, carboxyvinyl polymers, long-chain alkyl modified products of acrylic acid / methacrylic acid copolymers, natural water-soluble polymers such as polypeptides, casein, gelatin, etc. Is mentioned.

Of these, polyvinyl alcohol, polyacrylic acid salts and the like are insoluble in oil and have a poor ability to lower the interfacial tension, and therefore have the action of adsorbing to the oil droplet surface to prevent coalescence of the oil droplets. However, it is difficult to obtain a fine oil-in-water emulsion. There is also the problem of poor biodegradability.
A long-chain alkyl modified product of an acrylic acid / methacrylic acid copolymer has a certain degree of surface activity due to the long-chain alkyl portion in the structure and exerts an emulsifying power, but is insufficient, and is also poor in biodegradability. Natural water-soluble polymers such as polypeptides, casein, and gelatin have excellent biodegradability, but have poor emulsifying power, and because they are natural raw materials, there are large variations in performance between lots, which is a practical obstacle. . Further, as a method for compensating for the lack of emulsifying power of these water-soluble polymers, a method of using a water-soluble polymer and a surfactant in combination is disclosed.
Specifically, a method of combining a carboxyvinyl polymer with lecithin, sorbitan fatty acid ester or the like can be mentioned. According to this method, the emulsified particle size becomes relatively small and a stable emulsion can be obtained. However, environmental compatibility is problematic due to the low biodegradability of carboxyvinyl polymers.

[0006]

As a result of intensive studies to solve these problems, the present inventors have found that by combining an alkylated polysaccharide with a polyglycerin fatty acid ester, good emulsification performance, high environmental compatibility, and It was found that an oil-in-water emulsifier composition having biosafety can be obtained. Further, they have found that the use of these can provide a skin external preparation, cosmetics, and hair cosmetics having good emulsification performance, high environmental compatibility, and biosafety, and completed the present invention.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION The alkylated polysaccharides used in the present invention include seaweed extracts, seed mucilages, sap mucilages, fruit mucilages, microbial-produced mucilages, polysaccharides obtained from fibrin-based mucilages, or It is possible to use an alkylated product of these modified products, specifically, guar gum, locust bean gum, karaya gum, tragacanth gum, xanthan gum, cellulose, or an alkylated product of these modified products can be used. .

As the nonionic surfactant used in combination with the alkylated polysaccharide used in the present invention, an emulsion composition can be prepared if the HLB is 3-16. More preferably, when HLB is 5 to 7, a better emulsified state can be obtained. Nonionic surfactants having HLB of 3 to 16 include propylene glycol fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbit fatty acid ester, polyoxyethylene glycerin. Fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene hydrogenated castor oil, polyoxyethylene castor oil, polyoxyethylene / polyoxypropylene copolymer, polyoxyethylene / polyoxypropylene alkyl ether, etc. Can be used.

Among these nonionic surfactants, polyglycerin fatty acid ester is particularly preferable from the viewpoints of emulsified state, safety, and environmental compatibility.

The alkylated polysaccharide used in the present invention may be added in an amount of about 0.05% by weight to 2.0% by weight, preferably 0.1% by weight to 1.0% by weight. Alkylated polysaccharides take time to dissolve in water, so 2
An aqueous solution of about wt% may be prepared in advance and used.

The addition amount of the nonionic surfactant used in the present invention is 0.2% by weight or more, so that the emulsion composition can be prepared, but from the viewpoint of stability of the emulsion composition, it is 0.5.
% To 2% by weight is preferred.

In addition to the above-mentioned essential components, the external preparation for skin of the present invention contains a hardened oil derived from animal and vegetable oils as a component to be added to the external preparation for skin such as cosmetics and quasi-drugs as long as the effects of the present invention are not impaired. Naturally-derived wax, hydrocarbon-based oil phase component,
Animal- and plant-derived oil phase components, silicone-based oil phase components, fluorine-based oil phase components, higher alcohols, thickeners, ultraviolet absorbers, powders, pigments, anionic surfactants, cationic surfactants , Nonionic surfactants, polyhydric alcohols,
A sugar, a polymer compound, a physiologically active ingredient, a transdermal absorption enhancer, a solvent, an antioxidant, a fragrance, an antiseptic and the like can be added.

[0013]

The present invention will be described in more detail with reference to the following examples, but the technical scope of the present invention is not limited thereto. The blending amount is shown by weight%. (1) Sample Preparation Method The emulsified compositions of Examples and Comparative Examples were prepared according to the conventional oil-in-water emulsification method. (2) Evaluation method The emulsified composition is left at room temperature and a 45 ° C constant temperature bath for one month,
The emulsified state after standing was evaluated according to the following criteria. A: No separation of the oil phase and the water phase was observed. ◯: A slight separation of the aqueous phase was observed. Δ: Separation of oil phase and water phase was observed. X: The emulsification was completely separated.

[0014]

[Table 1]

[Table 2] As seen in Tables 1 and 2, alkylated polysaccharides and HL
When the nonionic surfactant of B3 to 16 is used in combination, more preferably, the nonionic surfactant of HLB of 5 to 7 is used in combination, a good emulsion composition is obtained. Furthermore, if polyglycerin fatty acid ester is used as the nonionic surfactant, it is possible to avoid the problem of skin irritation due to decomposition products when the ethylene oxide nonionic surfactant is used, and the safety is high, In addition, it can be expected that cosmetics having good environmental compatibility can be prepared.

Examples of more specific cosmetic formulations are shown below, but the technical scope of the present invention is not limited thereto. Example 6: Moisturizing cream (formulation) wt% Oil phase Macadamia nut oil 5.0 Squalane 5.0 Isooctyl palmitate 3.0 Decamethylcyclopentasiloxane 4.0 Behenyl alcohol 1.5 Hydrogenated soybean phospholipid 0.3 Tocopherol 0 1 Propylparaben 0.1 Aqueous phase Alkylated guar gum 0.5 Tetraglyceryl monostearate 1.5 Polyethylene glycol 2.0 Glycerin 1.5 1,3-Butylene glycol 1.5 Urea 1.0 Methylparaben 0.2 Water Remainder (preparation method) Preparation was carried out in the same manner as in Examples 1 to 5 and Comparative Examples 1 to 6. Example 7: Anti-aging cream (formulation) wt% Oil phase Triglyceryl tri-2-ethylhexanoate 6.0 Olive squalane 8.0 Decamethylcyclopentasiloxane 4.0 Methylpolysiloxane 0.3 Beeswax 1.5 Behenyl alcohol 1. 5 Ascorbyl tetra-2-hexyldecanoate 1.0 Stearyl glycyrrhetinate 0.2 4-tert-Butyl-4′-methoxydibenzylsoylmethane 0.3 Propylparaben 0.1 Aqueous phase alkylated hydroxyethylcellulose 0.5 Monostearate tetra Glyceryl 1.5 Glycerin 3.0 Hamamelis extract 0.2 Methylparaben 0.2 Water balance (preparation method) Prepared in the same manner as in Examples 1-5 and Comparative Examples 1-6. Example 8: Whitening cream (formulation) wt% Oil phase Liquid paraffin 10.0 Glyceryl tri-2-ethylhexanoate 10.0 Behenyl alcohol 1.5 Self-emulsifying monoglyceryl stearate 1.5 Propylparaben 0.1 Aqueous phase Alkyl Guar gum 0.5 Tetraglyceryl monostearate 1.5 Methylparaben 0.2 Magnesium L-ascorbyl phosphate 3.0 Water balance (preparation method) Prepared in the same manner as in Examples 1-5 and Comparative Examples 1-6. Example 9: Sunscreen cream (formulation) wt% Oil phase α-olefin oligomer 2.0 2-Ethylhexyl palmitate 3.0 Decamethylcyclopentanesiloxane 5.0 Octyl paramethoxycinnamate 6.0 Octyl salicylate 3. 0 propylparaben 0.1 water phase alkylated guar gum 0.5 tetraglyceryl monostearate 1.5 hexaglyceryl polyricinoleate 0.5 N-stearoylmethyltaurine sodium 0.3 methylparaben 0.2 1,3-butylene glycol 5 0.0 Water Remainder (preparation method) Prepared in the same manner as in Examples 1 to 5 and Comparative Examples 1 to 6. Example 10: Body emulsion (formulation) wt% Oil phase Macadamia nut oil 5.0 2-Ethylhexyl palmitate 3.0 Decamethylcyclopentanesiloxane 5.0 High molecular weight silicone 1.0 Behenyl alcohol 1.0 Propylparaben 0.1 Water phase Alkylated guar gum 0.5 Tetraglyceryl monostearate 1.5 Sodium stearoyl lactylate 0.05 Methylparaben 0.2 1,3-Butylene glycol 5.0 Glycerin 2.0 Polyethylene glycol 3.0 Water balance (preparation method) It was prepared in the same manner as in Examples 1 to 5 and Comparative Examples 1 to 6. (Evaluation method) It carried out like Example 1-5 and Comparative Examples 1-6.

[0016]

[Table 3] The cosmetic formulations of Examples 6 to 11 all show a good emulsified state.

[0017]

As described above in detail, the use of an alkylated polysaccharide in combination with a polyglycerin fatty acid ester provides an oil-in-water emulsifier composition having high environmental compatibility, high biosafety, and good stability. You can provide things. Further, by utilizing these, it is possible to provide a skin external preparation, a cosmetic composition, and a hair cosmetic composition, which have high environmental compatibility, biosafety, and good stability.

─────────────────────────────────────────────────── ─── Continuation of front page (51) Int.Cl. ⁷ Identification code FI theme code (reference) A61K 7/06 A61K 7/06 7/42 7/42 C08K 5/103 C08K 5/103 C08L 5/00 C08L 5/00 F-term (reference) 4C083 AA031 AA082 AA111 AA122 AC022 AC072 AC122 AC342 AC352 AC402 AC421 AC422 AC482 AC682 AC792 AD022 AD042 AD152 AD172 AD211 AD281 AD351 AD352 AD532 AD572 AD642 AD662 BB04 CC01 CC02 CC05 CC19 CC17 DD12 EE16 EE4 AB031 AB051 CH022 EH046 FD312 FD316 GB00

Claims (7)

[Claims] 1. An oil-in-water emulsifier composition comprising an alkylated polysaccharide and a nonionic surfactant of HLB 3-16. 2. The polysaccharide obtained from the alkylated polysaccharide according to claim 1, which is obtained from a seaweed extract, seed mucilage, sap mucilage, fruit mucilage, microbial mucilage, fibrin mucilage, or An oil-in-water emulsifier composition comprising one or two or more selected from alkylated polysaccharides obtained by alkylating the modified polysaccharides to make them hydrophobic. 3. The alkylated polysaccharide according to claim 1 is guar gum, hydroxyalkyl-modified guar gum,
An oil-in-water emulsifier composition comprising one or more selected from carboxyalkyl-modified guar gum and hydroxyalkyl / carboxyalkyl-modified guar gum that are further alkylated to be hydrophobic. 4. An oil-in-water emulsifier composition, wherein the alkylated polysaccharide according to any one of claims 1 and 2 is obtained by further alkylating hydroxyalkyl cellulose to make it hydrophobic. 5. An oil-in-water emulsifier composition, wherein the alkylation method of the alkylated polysaccharide according to any one of claims 1 to 4 is esterification, etherification, and / or glycidyl etherification. 6. The nonionic surfactant according to claim 1,
An oil-in-water emulsifier composition, which is a polyglycerin fatty acid ester. 7. A skin external preparation, a cosmetic, and a hair cosmetic using the emulsifier composition according to claim 1.