JO3561B1 - وحدة جهاز أدوية تحتوي على كويناجوليد - Google Patents
وحدة جهاز أدوية تحتوي على كويناجوليدInfo
- Publication number
- JO3561B1 JO3561B1 JOP/2015/0276A JOP20150276A JO3561B1 JO 3561 B1 JO3561 B1 JO 3561B1 JO P20150276 A JOP20150276 A JO P20150276A JO 3561 B1 JO3561 B1 JO 3561B1
- Authority
- JO
- Jordan
- Prior art keywords
- drug
- device unit
- poly
- quinagolide
- alkylene oxide
- Prior art date
Links
- GDFGTRDCCWFXTG-SCTDSRPQSA-N (3r,4ar,10as)-3-(diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2h-benzo[g]quinoline Chemical compound C1=CC=C2C[C@@H]3N(CCC)C[C@H](NS(=O)(=O)N(CC)CC)C[C@H]3CC2=C1O GDFGTRDCCWFXTG-SCTDSRPQSA-N 0.000 title abstract 2
- 229960000924 quinagolide Drugs 0.000 title abstract 2
- 229920001400 block copolymer Polymers 0.000 abstract 3
- 229920000233 poly(alkylene oxides) Polymers 0.000 abstract 2
- 229920002635 polyurethane Polymers 0.000 abstract 2
- 239000004814 polyurethane Substances 0.000 abstract 2
- 201000009273 Endometriosis Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/001—Combinations of extrusion moulding with other shaping operations
- B29C48/0021—Combinations of extrusion moulding with other shaping operations combined with joining, lining or laminating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2033/00—Use of polymers of unsaturated acids or derivatives thereof as moulding material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
- B29K2105/0035—Medical or pharmaceutical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/754—Pessaries
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Inorganic Chemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Mechanical Engineering (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Materials For Medical Uses (AREA)
Abstract
<span dir="RTL">يؤسس الاختراع الحالي على التعرف على مجموعة بوليمرات مشتركة كتلية من البولي بوليثان المعدة خصيصا للاستخدام في الوحدات البوليمرية الصيدلانية المؤلفة من أدوات توصيل الدواء والتي توفرتحكم محسن في إطلاق الدواء. تحديدا، يقدم الاختراع وحدات بوليمرية لأداة توصيل الدواء تشتمل على بوليمر مشترك كتلي من البولي يوريثان يمكن الحصول عله عن طريق مفاعلة المواد الآتية مع بعضها البعض: عديد (أكسيد الألكيلين)؛ مركب ثنائي الوظيفة؛ أيزوسيانات ثنائي الوظيفة؛ وإختياريا بوليمر مشترك كتلي يشتمل على كتل من عديد (أكسيد الألكيلين)؛ وكويناجوليد باعتباره عامل نشط دوائيا. يمكن أن تجد الوحدات البوليمرية لأداة توصيل الدواء تطبيقا في مجال معالجة و/أو منع الحالة المزمنة، المعروفة باسم مرض الانتباذ البطاني الرحمي. </span>
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14192372.2A EP3017809A1 (en) | 2014-11-07 | 2014-11-07 | Drug-device unit containing quinagolide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO3561B1 true JO3561B1 (ar) | 2020-07-05 |
Family
ID=51951583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOP/2015/0276A JO3561B1 (ar) | 2014-11-07 | 2015-11-05 | وحدة جهاز أدوية تحتوي على كويناجوليد |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US20180008535A1 (ar) |
| EP (3) | EP3017809A1 (ar) |
| JP (2) | JP6907120B2 (ar) |
| KR (1) | KR102612852B1 (ar) |
| CN (2) | CN106999422A (ar) |
| AR (1) | AR102571A1 (ar) |
| AU (2) | AU2015341734C1 (ar) |
| CA (1) | CA2966473A1 (ar) |
| CL (1) | CL2017001119A1 (ar) |
| CO (1) | CO2017005578A2 (ar) |
| DK (1) | DK3215118T3 (ar) |
| EA (2) | EA201991882A2 (ar) |
| ES (1) | ES2877973T3 (ar) |
| HR (1) | HRP20210961T1 (ar) |
| HU (1) | HUE054951T2 (ar) |
| IL (1) | IL252088B (ar) |
| JO (1) | JO3561B1 (ar) |
| LT (1) | LT3215118T (ar) |
| MA (2) | MA40897B1 (ar) |
| MD (1) | MD3215118T2 (ar) |
| MX (1) | MX379298B (ar) |
| MY (1) | MY193638A (ar) |
| NZ (1) | NZ731763A (ar) |
| PH (1) | PH12017550005A1 (ar) |
| PL (1) | PL3215118T3 (ar) |
| PT (1) | PT3215118T (ar) |
| RS (1) | RS62018B1 (ar) |
| SA (1) | SA517381471B1 (ar) |
| SG (1) | SG11201703596SA (ar) |
| SI (1) | SI3215118T1 (ar) |
| TN (1) | TN2017000175A1 (ar) |
| TW (1) | TWI685339B (ar) |
| UA (1) | UA122329C2 (ar) |
| WO (1) | WO2016071466A1 (ar) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11896685B2 (en) | 2018-10-31 | 2024-02-13 | Amorepacific Corporation | Core-shell network structure comprising biopolymer and composition comprising same |
| KR20210069344A (ko) | 2019-12-03 | 2021-06-11 | (주)아모레퍼시픽 | 바이오 폴리머를 포함하는 효능물질 전달체 |
| WO2023031218A1 (en) | 2021-08-31 | 2023-03-09 | Ferring B.V. | Diagnosis and treatment of ectopic endometriosis |
| WO2024153752A1 (en) | 2023-01-20 | 2024-07-25 | Ferring B.V. | Stereoselective synthesis of intermediates and synthesis of quinagolids |
| TW202528403A (zh) * | 2023-10-31 | 2025-07-16 | 德商巴斯夫歐洲公司 | 用於製造熱塑性聚氨酯之方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235988A (en) | 1976-12-13 | 1980-11-25 | Imperial Chemical Industries Limited | Delivery means for biologically active agents |
| US7833545B2 (en) | 2003-04-29 | 2010-11-16 | The General Hospital Corporation | Methods and devices for the sustained release of multiple drugs |
| ES2442675T3 (es) | 2003-07-10 | 2014-02-12 | Warner Chilcott (Ireland) Limited | Dispositivos intravaginales de suministro de fármacos |
| WO2005025549A2 (en) * | 2003-09-10 | 2005-03-24 | Noven Pharmaceuticals, Inc. | Multi-layer transdermal drug delivery device |
| ES2349657T3 (es) | 2005-04-29 | 2011-01-10 | Ferring International Center S.A. | Tratamiento o prevención del síndrome de hiperestimulación ovárica (sho) usando un agonista de domamina. |
| GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
| SA08290041B1 (ar) | 2007-02-01 | 2012-06-05 | فيرينج انترناشونال سنتر اس آيه | أدوية من أجل معالجة بطانة الرحم |
| AU2009206328A1 (en) | 2008-01-25 | 2009-07-30 | The University Of Utah Research Foundation | Linear order release polymer |
| NZ586792A (en) * | 2008-01-25 | 2012-09-28 | Gruenenthal Chemie | Tamper resistant controlled release pharmaceutical tablets form having convex and concave surfaces |
| US20100040671A1 (en) | 2008-08-12 | 2010-02-18 | Ahmed Salah U | Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof |
| US20100210600A1 (en) * | 2009-02-19 | 2010-08-19 | Prelief Inc. | Methods and Compositions for Treating Urogenital Disorders |
| WO2010150098A2 (en) * | 2009-06-26 | 2010-12-29 | Ferring International Center Sa | Treatment of endometriosis |
| WO2011127405A1 (en) * | 2010-04-08 | 2011-10-13 | Sanford-Burnham Medical Research Institute | Methods and compositions for enhanced delivery of compounds |
| WO2012066000A1 (en) | 2010-11-15 | 2012-05-24 | Dsm Ip Assets B.V. | Intravaginal drug delivery device comprising a polyurethane copolymer |
| AU2012283837B2 (en) * | 2011-07-20 | 2017-04-27 | Patrick F. Kiser | Intravaginal devices for drug delivery |
| US10137199B2 (en) * | 2013-05-14 | 2018-11-27 | Biotime, Inc. | Thiolated hyaluronan-based hydrogels cross-linked using oxidized glutathione |
| US10413504B2 (en) * | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
-
2014
- 2014-11-07 EP EP14192372.2A patent/EP3017809A1/en not_active Withdrawn
-
2015
- 2015-11-05 DK DK15790568.8T patent/DK3215118T3/da active
- 2015-11-05 SI SI201531573T patent/SI3215118T1/sl unknown
- 2015-11-05 US US15/524,792 patent/US20180008535A1/en not_active Abandoned
- 2015-11-05 MA MA40897A patent/MA40897B1/fr unknown
- 2015-11-05 EP EP15790568.8A patent/EP3215118B1/en active Active
- 2015-11-05 MA MA056414A patent/MA56414A/fr unknown
- 2015-11-05 CN CN201580067303.8A patent/CN106999422A/zh active Pending
- 2015-11-05 MD MDE20170069T patent/MD3215118T2/ro unknown
- 2015-11-05 EA EA201991882A patent/EA201991882A2/ru unknown
- 2015-11-05 EA EA201790898A patent/EA033806B9/ru not_active IP Right Cessation
- 2015-11-05 TN TN2017000175A patent/TN2017000175A1/en unknown
- 2015-11-05 SG SG11201703596SA patent/SG11201703596SA/en unknown
- 2015-11-05 HR HRP20210961TT patent/HRP20210961T1/hr unknown
- 2015-11-05 ES ES15790568T patent/ES2877973T3/es active Active
- 2015-11-05 PT PT157905688T patent/PT3215118T/pt unknown
- 2015-11-05 JP JP2017542330A patent/JP6907120B2/ja not_active Expired - Fee Related
- 2015-11-05 MY MYPI2017000673A patent/MY193638A/en unknown
- 2015-11-05 JO JOP/2015/0276A patent/JO3561B1/ar active
- 2015-11-05 NZ NZ731763A patent/NZ731763A/en unknown
- 2015-11-05 WO PCT/EP2015/075849 patent/WO2016071466A1/en not_active Ceased
- 2015-11-05 CN CN202310079847.2A patent/CN116212032A/zh active Pending
- 2015-11-05 EP EP21162634.6A patent/EP3892261A1/en not_active Withdrawn
- 2015-11-05 UA UAA201705500A patent/UA122329C2/uk unknown
- 2015-11-05 MX MX2017005828A patent/MX379298B/es unknown
- 2015-11-05 AU AU2015341734A patent/AU2015341734C1/en active Active
- 2015-11-05 LT LTEP15790568.8T patent/LT3215118T/lt unknown
- 2015-11-05 PL PL15790568T patent/PL3215118T3/pl unknown
- 2015-11-05 HU HUE15790568A patent/HUE054951T2/hu unknown
- 2015-11-05 CA CA2966473A patent/CA2966473A1/en active Pending
- 2015-11-05 RS RS20210767A patent/RS62018B1/sr unknown
- 2015-11-05 KR KR1020177015238A patent/KR102612852B1/ko active Active
- 2015-11-06 AR ARP150103620A patent/AR102571A1/es not_active Application Discontinuation
- 2015-11-06 TW TW104136694A patent/TWI685339B/zh not_active IP Right Cessation
-
2017
- 2017-05-03 IL IL252088A patent/IL252088B/en unknown
- 2017-05-05 CL CL2017001119A patent/CL2017001119A1/es unknown
- 2017-05-05 PH PH12017550005A patent/PH12017550005A1/en unknown
- 2017-05-06 SA SA517381471A patent/SA517381471B1/ar unknown
- 2017-06-05 CO CONC2017/0005578A patent/CO2017005578A2/es unknown
-
2020
- 2020-11-17 AU AU2020270480A patent/AU2020270480A1/en not_active Abandoned
-
2021
- 2021-05-10 US US17/316,208 patent/US20220040094A1/en not_active Abandoned
- 2021-06-30 JP JP2021108386A patent/JP2021155444A/ja active Pending
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