ITMI20040605A1 - BUTYRICAL ESTERS OF HYALURONIC ACID WITH LOW DEGREE OF SUBSTITUTION PROCEDURE FOR THEIR PREPARATION AND USE - Google Patents

BUTYRICAL ESTERS OF HYALURONIC ACID WITH LOW DEGREE OF SUBSTITUTION PROCEDURE FOR THEIR PREPARATION AND USE

Info

Publication number: ITMI20040605A1
Authority: IT; Italy
Prior art keywords: butyrical; esters; preparation; hyaluronic acid; low degree
Prior art date: 2004-03-29

Application number

Other languages

Italian (it)

Inventor

Danila Coradini

Alberto Perbellini

Original Assignee

Coimex S C R L United Companie

Danila Coradini

Alberto Perbellini

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-03-29

Filing date

2004-03-29

Publication date

2004-06-29

2004-03-29 Application filed by Coimex S C R L United Companie, Danila Coradini, Alberto Perbellini filed Critical Coimex S C R L United Companie

2004-03-29 Priority to ITMI20040605 priority Critical patent/ITMI20040605A1/en

2004-06-29 Publication of ITMI20040605A1 publication Critical patent/ITMI20040605A1/en

2005-03-25 Priority to PCT/IB2005/000780 priority patent/WO2005092929A1/en

2005-03-25 Priority to EP05718276A priority patent/EP1781707A1/en

Links

KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
229920002674 hyaluronan Polymers 0.000 title 1
229960003160 hyaluronic acid Drugs 0.000 title 1
238000000034 method Methods 0.000 title 1
238000006467 substitution reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Materials Engineering (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
Organic Chemistry (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ITMI20040605 2004-03-29 2004-03-29 BUTYRICAL ESTERS OF HYALURONIC ACID WITH LOW DEGREE OF SUBSTITUTION PROCEDURE FOR THEIR PREPARATION AND USE ITMI20040605A1 (en)

Priority Applications (3)

Application Number	Priority Date	Filing Date	Title
ITMI20040605 ITMI20040605A1 (en)	2004-03-29	2004-03-29	BUTYRICAL ESTERS OF HYALURONIC ACID WITH LOW DEGREE OF SUBSTITUTION PROCEDURE FOR THEIR PREPARATION AND USE
PCT/IB2005/000780 WO2005092929A1 (en)	2004-03-29	2005-03-25	Hyaluronic acid butyric esters with a low degree of substitution, procedure for their preparation and use
EP05718276A EP1781707A1 (en)	2004-03-29	2005-03-25	Hyaluronic acid butyric esters with a low degree of substitution, procedure for their preparation and use

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITMI20040605 ITMI20040605A1 (en)	2004-03-29	2004-03-29	BUTYRICAL ESTERS OF HYALURONIC ACID WITH LOW DEGREE OF SUBSTITUTION PROCEDURE FOR THEIR PREPARATION AND USE

Publications (1)

Publication Number	Publication Date
ITMI20040605A1 true ITMI20040605A1 (en)	2004-06-29

Family

ID=34967092

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ITMI20040605 ITMI20040605A1 (en)	2004-03-29	2004-03-29	BUTYRICAL ESTERS OF HYALURONIC ACID WITH LOW DEGREE OF SUBSTITUTION PROCEDURE FOR THEIR PREPARATION AND USE

Country Status (3)

Country	Link
EP (1)	EP1781707A1 (en)
IT (1)	ITMI20040605A1 (en)
WO (1)	WO2005092929A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN116444695A (en) *	2022-12-27	2023-07-18	山东丰金美业科技有限公司	Preparation method of low-cost low-molecular-weight acetylated sodium hyaluronate

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1942117A1 (en) *	2006-12-29	2008-07-09	Sigea S.R.L.	Derivatives of acid polysaccharides
ITMI20072237A1 (en) *	2007-11-27	2009-05-28	Sigea Srl	MIXED BUTIRRIC-FORMAL ESTERS OF ACID POLYSACCHARIDES, THEIR PREPARATION AND USE AS DERMOCOSMETICS
KR101078302B1 (en) *	2008-05-29	2011-10-31	(주)프로넥스	Drug Delivery System
ITTO20110428A1 (en)	2011-05-13	2012-11-14	Rottapharm Spa	ESTERS OF HYALURONIC ACID, THEIR PREPARATION AND USE IN DERMATOLOGY
CZ304654B6 (en)	2012-11-27	2014-08-20	Contipro Biotech S.R.O.	C6-C18-acylated hyaluronate-based nanomicellar composition, process for preparing C6-C18-acylated hyaluronate, process for preparing nanomicellar composition and stabilized nanomicellar composition as well as use thereof
CZ2013914A3 (en)	2013-11-21	2015-02-25	Contipro Biotech S.R.O.	Nanofibers containing photocurable ester derivative of hyaluronic acid or its salt, photocured nanofibers, method of their synthesis, preparation containing photo-hardened nanofibers and their use
CN103724455B (en) *	2013-12-11	2016-07-06	四川大学	A kind of preparation method of derivatives of hyaluronic acids and hydrogel thereof
CZ305153B6 (en)	2014-03-11	2015-05-20	Contipro Biotech S.R.O.	Conjugates of hyaluronic acid oligomer or a salt thereof, process for their preparation and use
CZ2014451A3 (en)	2014-06-30	2016-01-13	Contipro Pharma A.S.	Antitumor composition based on hyaluronic acid and inorganic nanoparticles, process of its preparation and use
PL3245233T3 (en)	2015-01-13	2019-06-28	Bmg Pharma S.P.A.	Process in water for the preparation of butyric esters of hyaluronic acid sodium salt
CZ309295B6 (en)	2015-03-09	2022-08-10	Contipro A.S.	Self-supporting, biodegradable film based on hydrophobized hyaluronic acid, method of its preparation and use
CZ2015398A3 (en)	2015-06-15	2017-02-08	Contipro A.S.	A method of crosslinking polysaccharides by using photolabile protecting groups
CZ306662B6 (en)	2015-06-26	2017-04-26	Contipro A.S.	Sulphated polysaccharides derivatives, the method of their preparation, the method of their modification and the use
CZ308106B6 (en)	2016-06-27	2020-01-08	Contipro A.S.	Unsaturated derivatives of polysaccharides, preparing and using them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1286510B1 (en) *	1996-11-29	1998-07-15	Cooperativa Centro Ricerche Po	BUTYRIC ESTERS WITH ANTI-PROLIFERATIVE ACTIVITY AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM

2004
- 2004-03-29 IT ITMI20040605 patent/ITMI20040605A1/en unknown
2005
- 2005-03-25 WO PCT/IB2005/000780 patent/WO2005092929A1/en not_active Ceased
- 2005-03-25 EP EP05718276A patent/EP1781707A1/en not_active Withdrawn

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN116444695A (en) *	2022-12-27	2023-07-18	山东丰金美业科技有限公司	Preparation method of low-cost low-molecular-weight acetylated sodium hyaluronate

Also Published As

Publication number	Publication date
WO2005092929A1 (en)	2005-10-06
WO2005092929A8 (en)	2006-03-02
EP1781707A1 (en)	2007-05-09

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