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ITMI961290A0 - - Google Patents

Info

Publication number
ITMI961290A0
ITMI961290A0 ITMI961290A ITMI961290A ITMI961290A0 IT MI961290 A0 ITMI961290 A0 IT MI961290A0 IT MI961290 A ITMI961290 A IT MI961290A IT MI961290 A ITMI961290 A IT MI961290A IT MI961290 A0 ITMI961290 A0 IT MI961290A0
Authority
IT
Italy
Application number
ITMI961290A
Other languages
Italian (it)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to IT96MI001290A priority Critical patent/IT1284070B1/en
Publication of ITMI961290A0 publication Critical patent/ITMI961290A0/it
Priority to AU32608/97A priority patent/AU3260897A/en
Priority to PCT/EP1997/003190 priority patent/WO1997049711A1/en
Publication of ITMI961290A1 publication Critical patent/ITMI961290A1/en
Application granted granted Critical
Publication of IT1284070B1 publication Critical patent/IT1284070B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4025—Esters of poly(thio)phosphonic acids
    • C07F9/4046—Esters of poly(thio)phosphonic acids containing carboxylic acid or carboxylic acid derivative substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3869—Polyphosphonic acids containing carboxylic acid or carboxylic acid derivative substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/564—Three-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT96MI001290A 1996-06-26 1996-06-26 CARBOXY GEM-DIPHOSPHONATE DERIVATIVES WITH ANTI-CANCER ACTIVITY, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS WHICH IT1284070B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT96MI001290A IT1284070B1 (en) 1996-06-26 1996-06-26 CARBOXY GEM-DIPHOSPHONATE DERIVATIVES WITH ANTI-CANCER ACTIVITY, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS WHICH
AU32608/97A AU3260897A (en) 1996-06-26 1997-06-12 Derivatives of carboxy gem-bisphosphonates with antitumor activity, a process for preparing them and pharmaceutical compositions containing them
PCT/EP1997/003190 WO1997049711A1 (en) 1996-06-26 1997-06-12 Derivatives of carboxy gem-bisphosphonates with antitumor activity, a process for preparing them and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI001290A IT1284070B1 (en) 1996-06-26 1996-06-26 CARBOXY GEM-DIPHOSPHONATE DERIVATIVES WITH ANTI-CANCER ACTIVITY, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS WHICH

Publications (3)

Publication Number Publication Date
ITMI961290A0 true ITMI961290A0 (en) 1996-06-26
ITMI961290A1 ITMI961290A1 (en) 1997-12-26
IT1284070B1 IT1284070B1 (en) 1998-05-08

Family

ID=11374479

Family Applications (1)

Application Number Title Priority Date Filing Date
IT96MI001290A IT1284070B1 (en) 1996-06-26 1996-06-26 CARBOXY GEM-DIPHOSPHONATE DERIVATIVES WITH ANTI-CANCER ACTIVITY, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS WHICH

Country Status (3)

Country Link
AU (1) AU3260897A (en)
IT (1) IT1284070B1 (en)
WO (1) WO1997049711A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1290444B1 (en) 1997-03-27 1998-12-03 Boehringer Mannheim Italia CONJUGATES OF BIS-PHOSPHONATES WITH ALKYLANTS FUNCTIONALITY HAVING ANTI-TUMOR ACTIVITIES
WO2003008425A1 (en) 2001-07-16 2003-01-30 Universite Paris 13 Novel bisphosphonate derivatives, their preparation methods and uses
DE102004032781A1 (en) * 2004-01-23 2005-08-11 Mcs Micro Carrier Systems Gmbh New lipid-modified bis-phosphonic acid derivatives, useful e.g. for transporting therapeutic or diagnostic agents, with affinity for bone, also as corrosion inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3425812A1 (en) * 1984-07-13 1986-01-16 Deutsches Krebsforschungszentrum, 6900 Heidelberg NEW 1-HYDROXY-1,1-DIPHOSPHONIC ACID COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PHARMACOLOGICAL PREPARATIONS, IN PARTICULAR FOR THE TREATMENT OF BONE TUMORS
FR2611203B1 (en) * 1987-02-20 1989-06-09 Sturtz Georges GEM-DIPHOSPHONIC ANALOGS OF AMETHOPTERIN (METHOTREXATE) AND DEAZA-N-10 AMETHOPTERINE DERIVATIVES. THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IT1241674B (en) * 1989-10-12 1994-01-27 Boehringer Biochemia Srl GEM-DIPHOSPHONIC ACIDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
IT1246777B (en) * 1991-04-12 1994-11-26 Boehringer Mannheim Italia AMINOACIL DERIVATIVES OF GEM-DIPHOSPHONIC ACIDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM

Also Published As

Publication number Publication date
WO1997049711A1 (en) 1997-12-31
AU3260897A (en) 1998-01-14
IT1284070B1 (en) 1998-05-08
ITMI961290A1 (en) 1997-12-26

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Legal Events

Date Code Title Description
0001 Granted