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ITMI940696A0 - Derivati dell'acido fosfonico utili nel trattamento delle malattie cardiovascolari - Google Patents

Derivati dell'acido fosfonico utili nel trattamento delle malattie cardiovascolari

Info

Publication number
ITMI940696A0
ITMI940696A0 ITMI940696A ITMI940696A ITMI940696A0 IT MI940696 A0 ITMI940696 A0 IT MI940696A0 IT MI940696 A ITMI940696 A IT MI940696A IT MI940696 A ITMI940696 A IT MI940696A IT MI940696 A0 ITMI940696 A0 IT MI940696A0
Authority
IT
Italy
Prior art keywords
derivatives
treatment
phosphonic acid
cardiovascular diseases
acid useful
Prior art date
Application number
ITMI940696A
Other languages
English (en)
Inventor
Gabriele Norcini
Gabriele Morazzoni
Francesco Santangelo
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of ITMI940696A0 publication Critical patent/ITMI940696A0/it
Priority to ITMI940696A priority Critical patent/IT1274673B/it
Priority to DE69511689T priority patent/DE69511689T2/de
Priority to AU23058/95A priority patent/AU2305895A/en
Priority to AT95916625T priority patent/ATE183750T1/de
Priority to ES95916625T priority patent/ES2136848T3/es
Priority to US08/702,701 priority patent/US5760285A/en
Priority to PCT/EP1995/001322 priority patent/WO1995028417A1/en
Priority to EP95916625A priority patent/EP0755405B1/en
Publication of ITMI940696A1 publication Critical patent/ITMI940696A1/it
Application granted granted Critical
Publication of IT1274673B publication Critical patent/IT1274673B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ITMI940696A 1994-04-14 1994-04-14 Derivati dell'acido fosfonico utili nel trattamento delle malattie car.iovascolari IT1274673B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ITMI940696A IT1274673B (it) 1994-04-14 1994-04-14 Derivati dell'acido fosfonico utili nel trattamento delle malattie car.iovascolari
ES95916625T ES2136848T3 (es) 1994-04-14 1995-04-11 Fosfonildipeptidos utiles para el tratamiento de enfermedades cardiovasculares.
AU23058/95A AU2305895A (en) 1994-04-14 1995-04-11 Phosphonyldipeptides useful in the treatment of cardiovascular diseases
AT95916625T ATE183750T1 (de) 1994-04-14 1995-04-11 Phosphonyldipeptide zur bekämpfung von kardiovasvakuläre erkrankungen
DE69511689T DE69511689T2 (de) 1994-04-14 1995-04-11 Phosphonyldipeptide zur bekämpfung von kardiovasvakuläre erkrankungen
US08/702,701 US5760285A (en) 1994-04-14 1995-04-11 Phosphonyldipeptides useful in the treatment of cardiovascular diseases
PCT/EP1995/001322 WO1995028417A1 (en) 1994-04-14 1995-04-11 Phosphonyldipeptides useful in the treatment of cardiovascular diseases
EP95916625A EP0755405B1 (en) 1994-04-14 1995-04-11 Phosphonyldipeptides useful in the treatment of cardiovascular diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI940696A IT1274673B (it) 1994-04-14 1994-04-14 Derivati dell'acido fosfonico utili nel trattamento delle malattie car.iovascolari

Publications (3)

Publication Number Publication Date
ITMI940696A0 true ITMI940696A0 (it) 1994-04-14
ITMI940696A1 ITMI940696A1 (it) 1995-10-14
IT1274673B IT1274673B (it) 1997-07-24

Family

ID=11368561

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI940696A IT1274673B (it) 1994-04-14 1994-04-14 Derivati dell'acido fosfonico utili nel trattamento delle malattie car.iovascolari

Country Status (8)

Country Link
US (1) US5760285A (it)
EP (1) EP0755405B1 (it)
AT (1) ATE183750T1 (it)
AU (1) AU2305895A (it)
DE (1) DE69511689T2 (it)
ES (1) ES2136848T3 (it)
IT (1) IT1274673B (it)
WO (1) WO1995028417A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1276161B1 (it) * 1995-11-23 1997-10-27 Zambon Spa Derivati dell'acido fosfonico ad attivita' inibitrice delle metallopeptidasi
US6166052A (en) * 1998-03-11 2000-12-26 Warner-Lambert Company Heteroaryl alkyl alpha substituted peptidylamine calcium channel blockers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379146A (en) * 1981-02-17 1983-04-05 Merck & Co., Inc. Substituted phosphonamides as antihypertensives
US4432972A (en) * 1981-08-03 1984-02-21 E. R. Squibb & Sons, Inc. Phosphonamidate compounds
IT1224405B (it) * 1987-12-23 1990-10-04 Simes Composti attivi sul sistema cardiovascolare
FR2652087B1 (fr) * 1989-09-15 1993-10-15 Bioprojet Ste Civile Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques.
US5294632A (en) * 1991-05-01 1994-03-15 Ciba-Geigy Corporation Phosphono/biaryl substituted dipetide derivatives
US5155100A (en) * 1991-05-01 1992-10-13 Ciba-Geigy Corporation Phosphono/biaryl substituted dipeptide derivatives
JPH05105698A (ja) * 1991-06-13 1993-04-27 Takeda Chem Ind Ltd ホスホン酸誘導体、その製造法および用途
IT1254521B (it) * 1992-03-17 1995-09-25 Zambon Spa Derivati della 2-ammino-tetralina attivi sul sistema cardiovascolare

Also Published As

Publication number Publication date
EP0755405A1 (en) 1997-01-29
US5760285A (en) 1998-06-02
ATE183750T1 (de) 1999-09-15
WO1995028417A1 (en) 1995-10-26
IT1274673B (it) 1997-07-24
ITMI940696A1 (it) 1995-10-14
AU2305895A (en) 1995-11-10
ES2136848T3 (es) 1999-12-01
EP0755405B1 (en) 1999-08-25
DE69511689D1 (de) 1999-09-30
DE69511689T2 (de) 2000-04-27

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971020