ITMC20060080A1 - CHEMICAL SYNTHESIS OF (64-COPPER (I) ASPARAGINASE; [64CU (I)] ASPARAGINASI), AND USE OF THE SAME AS AN AGENT FOR PET INVESTIGATIONS (POSITRON EMISSION TOMOGRAPHY) AND FOR RADIOTHERAPY. - Google Patents
CHEMICAL SYNTHESIS OF (64-COPPER (I) ASPARAGINASE; [64CU (I)] ASPARAGINASI), AND USE OF THE SAME AS AN AGENT FOR PET INVESTIGATIONS (POSITRON EMISSION TOMOGRAPHY) AND FOR RADIOTHERAPY.Info
- Publication number
- ITMC20060080A1 ITMC20060080A1 IT000080A ITMC20060080A ITMC20060080A1 IT MC20060080 A1 ITMC20060080 A1 IT MC20060080A1 IT 000080 A IT000080 A IT 000080A IT MC20060080 A ITMC20060080 A IT MC20060080A IT MC20060080 A1 ITMC20060080 A1 IT MC20060080A1
- Authority
- IT
- Italy
- Prior art keywords
- asparaginasi
- asparaginase
- radiotherapy
- copper
- agent
- Prior art date
Links
- 102000015790 Asparaginase Human genes 0.000 title 1
- 108010024976 Asparaginase Proteins 0.000 title 1
- 229960003272 asparaginase Drugs 0.000 title 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-M asparaginate Chemical compound [O-]C(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-M 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 238000002600 positron emission tomography Methods 0.000 title 1
- 238000001959 radiotherapy Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
- C12N9/82—Asparaginase (3.5.1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/008—Peptides; Proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000080A ITMC20060080A1 (en) | 2006-06-23 | 2006-06-23 | CHEMICAL SYNTHESIS OF (64-COPPER (I) ASPARAGINASE; [64CU (I)] ASPARAGINASI), AND USE OF THE SAME AS AN AGENT FOR PET INVESTIGATIONS (POSITRON EMISSION TOMOGRAPHY) AND FOR RADIOTHERAPY. |
| PCT/EP2007/001317 WO2007147454A1 (en) | 2006-06-23 | 2007-02-15 | Chemical synthesis of cu-64asp (copper-64asparaginase; [64cu]asparaginase) for pet scans and radiotheraphy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000080A ITMC20060080A1 (en) | 2006-06-23 | 2006-06-23 | CHEMICAL SYNTHESIS OF (64-COPPER (I) ASPARAGINASE; [64CU (I)] ASPARAGINASI), AND USE OF THE SAME AS AN AGENT FOR PET INVESTIGATIONS (POSITRON EMISSION TOMOGRAPHY) AND FOR RADIOTHERAPY. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITMC20060080A1 true ITMC20060080A1 (en) | 2007-12-24 |
Family
ID=37946266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000080A ITMC20060080A1 (en) | 2006-06-23 | 2006-06-23 | CHEMICAL SYNTHESIS OF (64-COPPER (I) ASPARAGINASE; [64CU (I)] ASPARAGINASI), AND USE OF THE SAME AS AN AGENT FOR PET INVESTIGATIONS (POSITRON EMISSION TOMOGRAPHY) AND FOR RADIOTHERAPY. |
Country Status (2)
| Country | Link |
|---|---|
| IT (1) | ITMC20060080A1 (en) |
| WO (1) | WO2007147454A1 (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005069994A2 (en) * | 2004-01-22 | 2005-08-04 | Immunomedics, Inc. | Folate conjugates and complexes |
-
2006
- 2006-06-23 IT IT000080A patent/ITMC20060080A1/en unknown
-
2007
- 2007-02-15 WO PCT/EP2007/001317 patent/WO2007147454A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007147454A1 (en) | 2007-12-27 |
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