ITFI930187A1 - Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono. - Google Patents

Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.

Info

Publication number: ITFI930187A1
Authority: IT; Italy
Prior art keywords: disaccarides; anthracycline; pharmaceutical compositions; compositions containing; preparation processes
Prior art date: 1993-09-30

Application number

IT000187A

Other languages

English (en)

Inventor

Fabio Animati

Federico Arcamone

Amalia Cipollone

Paolo Lombardi

Original Assignee

Menarini Farma Ind

Bristol Myers Squibb Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-09-30

Filing date

1993-09-30

Publication date

1995-03-30

1993-09-30 Application filed by Menarini Farma Ind, Bristol Myers Squibb Spa filed Critical Menarini Farma Ind

1993-09-30 Publication of ITFI930187A0 publication Critical patent/ITFI930187A0/it

1993-09-30 Priority to ITFI930187A priority Critical patent/IT1262565B/it

1994-09-26 Priority to DK94927649T priority patent/DK0721456T3/da

1994-09-26 Priority to SI9430262T priority patent/SI0721456T1/xx

1994-09-26 Priority to DE69417907T priority patent/DE69417907T2/de

1994-09-26 Priority to ES94927649T priority patent/ES2132429T3/es

1994-09-26 Priority to PL94313708A priority patent/PL179399B1/pl

1994-09-26 Priority to AU76986/94A priority patent/AU688374B2/en

1994-09-26 Priority to AT94927649T priority patent/ATE178901T1/de

1994-09-26 Priority to HU9600812A priority patent/HU227309B1/hu

1994-09-26 Priority to CA002173158A priority patent/CA2173158C/en

1994-09-26 Priority to CN94194276A priority patent/CN1042032C/zh

1994-09-26 Priority to UA96031231A priority patent/UA41951C2/uk

1994-09-26 Priority to KR1019960701668A priority patent/KR100341166B1/ko

1994-09-26 Priority to NZ273624A priority patent/NZ273624A/en

1994-09-26 Priority to EP94927649A priority patent/EP0721456B1/en

1994-09-26 Priority to PCT/EP1994/003201 priority patent/WO1995009173A1/en

1994-09-26 Priority to GEAP19943110A priority patent/GEP20002095B/en

1994-09-26 Priority to SK396-96A priority patent/SK281797B6/sk

1994-09-26 Priority to RO96-00687A priority patent/RO115525B1/ro

1994-09-26 Priority to JP51010695A priority patent/JP3836503B2/ja

1994-09-26 Priority to CZ1996904A priority patent/CZ288462B6/cs

1994-09-26 Priority to RU96110287A priority patent/RU2144540C1/ru

1994-09-26 Priority to BR9407679A priority patent/BR9407679A/pt

1995-03-28 Priority to TW084103178A priority patent/TW404950B/zh

1995-03-30 Publication of ITFI930187A1 publication Critical patent/ITFI930187A1/it

1996-03-15 Priority to NO961061A priority patent/NO305400B1/no

1996-03-28 Priority to US08/644,602 priority patent/US5801152A/en

1996-03-29 Priority to FI961423A priority patent/FI113541B/fi

1996-03-29 Priority to BG100466A priority patent/BG62289B1/bg

1996-07-04 Application granted granted Critical

1996-07-04 Publication of IT1262565B publication Critical patent/IT1262565B/it

1997-05-13 Priority to BR1100550-5A priority patent/BR1100550A/pt

1999-07-09 Priority to GR990401810T priority patent/GR3030731T3/el

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ITFI930187A 1993-09-30 1993-09-30 Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono. IT1262565B (it)

Priority Applications (30)

Application Number	Priority Date	Filing Date	Title
ITFI930187A IT1262565B (it)	1993-09-30	1993-09-30	Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.
EP94927649A EP0721456B1 (en)	1993-09-30	1994-09-26	Anthracycline disaccharides, process for their preparation, and pharmaceutical compositions containing them
PCT/EP1994/003201 WO1995009173A1 (en)	1993-09-30	1994-09-26	Anthracycline disaccharides, process for their preparation, and pharmaceutical compositions containing them
DE69417907T DE69417907T2 (de)	1993-09-30	1994-09-26	Anthracyclin-disaccharide, verfahren zu ihrer herstellung, und diese enthaltende arzneimittel
ES94927649T ES2132429T3 (es)	1993-09-30	1994-09-26	Disacaridos de antraciclina, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
PL94313708A PL179399B1 (pl)	1993-09-30	1994-09-26	Nowe antracyklino-disacharydy, sposób ich wytwarzaniai preparaty farmaceutyczne zawierajace antracyklino-disacharydy PL PL PL PL PL PL PL
AU76986/94A AU688374B2 (en)	1993-09-30	1994-09-26	Anthracycline disaccharides, process for their preparation, and pharmaceutical compositions containing them
AT94927649T ATE178901T1 (de)	1993-09-30	1994-09-26	Anthracyclin-disaccharide, verfahren zu ihrer herstellung, und diese enthaltende arzneimittel
HU9600812A HU227309B1 (en)	1993-09-30	1994-09-26	Anthracycline disaccharides, process for their preparation, and pharmaceutical compositions containing the said compds.
SK396-96A SK281797B6 (sk)	1993-09-30	1994-09-26	Antracyklínové disacharidy, spôsob ich prípravy a farmaceutické prípravky s ich obsahom
CN94194276A CN1042032C (zh)	1993-09-30	1994-09-26	蒽环二糖类、其制备方法和含有它们的药物组合物
UA96031231A UA41951C2 (uk)	1993-09-30	1994-09-26	Антрациклінові дисахариди, спосіб їх одержання та фармацевтичні композиції, які їх містять
KR1019960701668A KR100341166B1 (ko)	1993-09-30	1994-09-26	안트라사이클린디사카라이드,이의제조방법및이를함유하는약학조성물
NZ273624A NZ273624A (en)	1993-09-30	1994-09-26	Anthracycline disaccharide derivatives, preparation and pharmaceutical compositions thereof
DK94927649T DK0721456T3 (da)	1993-09-30	1994-09-26	Anthracyclindisaccharider, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende dem
GEAP19943110A GEP20002095B (en)	1993-09-30	1994-09-26	Antracycline Disaccharides, Process for Their Preparation and Pharmaceutical Compositions
RO96-00687A RO115525B1 (ro)	1993-09-30	1994-09-26	Derivati de dizaharide ale antraciclinei procedeu pentru prepararea acestora si compozitie farmaceutica continand acesti derivati
CA002173158A CA2173158C (en)	1993-09-30	1994-09-26	Anthracycline disaccharides, process for their preparation, and pharmaceutical compositions containing them
SI9430262T SI0721456T1 (en)	1993-09-30	1994-09-26	Anthracycline disaccharides, process for their preparation, and pharmaceutical compositions containing them
JP51010695A JP3836503B2 (ja)	1993-09-30	1994-09-26	アントラサイクリン二糖類、それらの調製方法、およびそれらを含む医薬組成物
CZ1996904A CZ288462B6 (en)	1993-09-30	1994-09-26	Anthracycline disaccharides, process of their preparation and pharmaceutical preparations with in which the disaccharides are comprised
RU96110287A RU2144540C1 (ru)	1993-09-30	1994-09-26	Антрациклиновые дисахариды, способ их получения и содержащие их фармацевтические композиции
BR9407679A BR9407679A (pt)	1993-09-30	1994-09-26	Disacarídeos de antraciclina processo para sua preparaçao e composiçoes farmacêuticas contendo os mesmos
TW084103178A TW404950B (en)	1993-09-30	1995-03-28	Anthracycline disaccharides, process for their preparation, and pharmaceutical compositions containing them
NO961061A NO305400B1 (no)	1993-09-30	1996-03-15	Terapeutisk aktive antracyclin-disakkarider
US08/644,602 US5801152A (en)	1993-09-30	1996-03-28	Antracycline disaccharides, process for their preparation, and pharmaceutical compositions containing them
FI961423A FI113541B (fi)	1993-09-30	1996-03-29	Menetelmä antrasykliinidisakkaridien valmistamiseksi
BG100466A BG62289B1 (bg)	1993-09-30	1996-03-29	Антрациклинови дизахариди, метод за тяхното получаване ифармацевтични състави на тяхна основа
BR1100550-5A BR1100550A (pt)	1993-09-30	1997-05-13	Disacarìdeos de antraciclina, processo para sua preparação, e composições farmacêuticas contendo os mesmos
GR990401810T GR3030731T3 (en)	1993-09-30	1999-07-09	Anthracycline disaccharides, process for their preparation, and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITFI930187A IT1262565B (it)	1993-09-30	1993-09-30	Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.

Publications (3)

Publication Number	Publication Date
ITFI930187A0 ITFI930187A0 (it)	1993-09-30
ITFI930187A1 true ITFI930187A1 (it)	1995-03-30
IT1262565B IT1262565B (it)	1996-07-04

Family

ID=11350615

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ITFI930187A IT1262565B (it)	1993-09-30	1993-09-30	Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.

Country Status (27)

Country	Link
US (1)	US5801152A (it)
EP (1)	EP0721456B1 (it)
JP (1)	JP3836503B2 (it)
KR (1)	KR100341166B1 (it)
CN (1)	CN1042032C (it)
AT (1)	ATE178901T1 (it)
AU (1)	AU688374B2 (it)
BG (1)	BG62289B1 (it)
BR (2)	BR9407679A (it)
CZ (1)	CZ288462B6 (it)
DE (1)	DE69417907T2 (it)
DK (1)	DK0721456T3 (it)
ES (1)	ES2132429T3 (it)
FI (1)	FI113541B (it)
GE (1)	GEP20002095B (it)
GR (1)	GR3030731T3 (it)
HU (1)	HU227309B1 (it)
IT (1)	IT1262565B (it)
NO (1)	NO305400B1 (it)
NZ (1)	NZ273624A (it)
PL (1)	PL179399B1 (it)
RO (1)	RO115525B1 (it)
RU (1)	RU2144540C1 (it)
SK (1)	SK281797B6 (it)
TW (1)	TW404950B (it)
UA (1)	UA41951C2 (it)
WO (1)	WO1995009173A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1271689B (it) *	1994-08-04	1997-06-04	Menarini Farma Ind	8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
IT1307846B1 (it) *	1999-03-09	2001-11-19	Menarini Ricerche Spa	L-arabino disaccaridi di antracicline, loro processi di preparazione ecomposizioni farmaceutiche che li contengono.
CN112010913B (zh) *	2019-05-31	2022-06-21	南京正大天晴制药有限公司	4-脱氧柔红霉素的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1561507A (en) *	1976-11-17	1980-02-20	Farmaceutici Italia	Snthracycline disaccharides
US4302249A (en) *	1978-04-21	1981-11-24	Chernogorenko Vasily B	Method for processing wastes resulting from production of phosphorus namely, slime and off-gases, with utilization of the resultant products
US4201773A (en) *	1978-07-26	1980-05-06	The United States Of America As Represented By The Department Of Health, Education And Welfare	7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
AU554416B2 (en) *	1982-05-24	1986-08-21	Farmitalia Carlo Erba S.P.A.	Anthracycline glycosides
DE3641833A1 (de) *	1986-12-08	1988-06-09	Behringwerke Ag	Zytostatisch wirksame anthracyclinderivate
US4918172A (en) *	1987-10-06	1990-04-17	Sanraku Incorporated	Anthracycline antibiotics
AU608415B2 (en) *	1988-01-19	1991-03-28	University Of Texas System, The	Esters of 3'-deaminodoxorubicin, liposomal compositions thereof
WO1990007519A1 (en) *	1988-12-28	1990-07-12	Board Of Regents, The University Of Texas System	3'-deamino analogs of esorubicin and methods for their use
IT1241927B (it) *	1990-05-14	1994-02-01	Menarini Farma Ind	3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono
WO1992007862A1 (en) *	1990-10-30	1992-05-14	Yale University	Antibiotics improved by conjugation with stereospecific carbohydrtes and methods for carbohydrate stereoselectivity

1993
- 1993-09-30 IT ITFI930187A patent/IT1262565B/it active IP Right Grant
1994
- 1994-09-26 PL PL94313708A patent/PL179399B1/pl not_active IP Right Cessation
- 1994-09-26 SK SK396-96A patent/SK281797B6/sk not_active IP Right Cessation
- 1994-09-26 EP EP94927649A patent/EP0721456B1/en not_active Expired - Lifetime
- 1994-09-26 KR KR1019960701668A patent/KR100341166B1/ko not_active Expired - Fee Related
- 1994-09-26 AT AT94927649T patent/ATE178901T1/de active
- 1994-09-26 BR BR9407679A patent/BR9407679A/pt not_active Application Discontinuation
- 1994-09-26 RU RU96110287A patent/RU2144540C1/ru not_active IP Right Cessation
- 1994-09-26 RO RO96-00687A patent/RO115525B1/ro unknown
- 1994-09-26 DK DK94927649T patent/DK0721456T3/da active
- 1994-09-26 CZ CZ1996904A patent/CZ288462B6/cs not_active IP Right Cessation
- 1994-09-26 UA UA96031231A patent/UA41951C2/uk unknown
- 1994-09-26 DE DE69417907T patent/DE69417907T2/de not_active Expired - Lifetime
- 1994-09-26 HU HU9600812A patent/HU227309B1/hu not_active IP Right Cessation
- 1994-09-26 WO PCT/EP1994/003201 patent/WO1995009173A1/en not_active Ceased
- 1994-09-26 AU AU76986/94A patent/AU688374B2/en not_active Ceased
- 1994-09-26 GE GEAP19943110A patent/GEP20002095B/en unknown
- 1994-09-26 ES ES94927649T patent/ES2132429T3/es not_active Expired - Lifetime
- 1994-09-26 NZ NZ273624A patent/NZ273624A/en not_active IP Right Cessation
- 1994-09-26 JP JP51010695A patent/JP3836503B2/ja not_active Expired - Fee Related
- 1994-09-26 CN CN94194276A patent/CN1042032C/zh not_active Expired - Lifetime
1995
- 1995-03-28 TW TW084103178A patent/TW404950B/zh not_active IP Right Cessation
1996
- 1996-03-15 NO NO961061A patent/NO305400B1/no not_active IP Right Cessation
- 1996-03-28 US US08/644,602 patent/US5801152A/en not_active Expired - Lifetime
- 1996-03-29 BG BG100466A patent/BG62289B1/bg unknown
- 1996-03-29 FI FI961423A patent/FI113541B/fi not_active IP Right Cessation
1997
- 1997-05-13 BR BR1100550-5A patent/BR1100550A/pt active IP Right Grant
1999
- 1999-07-09 GR GR990401810T patent/GR3030731T3/el unknown

Also Published As

Publication number	Publication date
NO305400B1 (no)	1999-05-25
CZ90496A3 (en)	1997-03-12
WO1995009173A1 (en)	1995-04-06
PL313708A1 (en)	1996-07-22
AU7698694A (en)	1995-04-18
GEP20002095B (en)	2000-05-10
AU688374B2 (en)	1998-03-12
BR1100550A (pt)	2000-03-14
US5801152A (en)	1998-09-01
DE69417907D1 (de)	1999-05-20
FI961423L (fi)	1996-03-29
JPH09502990A (ja)	1997-03-25
ATE178901T1 (de)	1999-04-15
NO961061D0 (no)	1996-03-15
BR9407679A (pt)	1997-03-04
JP3836503B2 (ja)	2006-10-25
ES2132429T3 (es)	1999-08-16
KR100341166B1 (ko)	2002-11-11
NZ273624A (en)	1998-01-26
HU9600812D0 (en)	1996-05-28
FI113541B (fi)	2004-05-14
GR3030731T3 (en)	1999-11-30
EP0721456A1 (en)	1996-07-17
TW404950B (en)	2000-09-11
EP0721456B1 (en)	1999-04-14
DE69417907T2 (de)	1999-08-12
RU2144540C1 (ru)	2000-01-20
FI961423A0 (fi)	1996-03-29
HUT75343A (en)	1997-05-28
SK281797B6 (sk)	2001-08-06
ITFI930187A0 (it)	1993-09-30
BG62289B1 (bg)	1999-07-30
CN1042032C (zh)	1999-02-10
PL179399B1 (pl)	2000-08-31
HU227309B1 (en)	2011-03-28
NO961061L (no)	1996-03-15
SK39696A3 (en)	1996-11-06
DK0721456T3 (da)	1999-10-25
CZ288462B6 (en)	2001-06-13
IT1262565B (it)	1996-07-04
CN1136317A (zh)	1996-11-20
BG100466A (bg)	1996-11-29
UA41951C2 (uk)	2001-10-15
RO115525B1 (ro)	2000-03-30

Publication	Publication Date	Title
ITFI930083A1 (it)	1994-10-26	Composti pirrol-amidinici, processi di preparazione e composizioni farmaceutiche che li contengono.
FI922364L (fi)	1992-05-22	Farmaceutiska kompositioner.
IL112193A0 (en)	1995-03-15	Phenylpyrazolopyridine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IT8920486A0 (it)	1989-05-12	Composizioni farmaceutiche.
HUP0102215A3 (en)	2002-05-28	Benzoylpyridazines, pharmaceutical compositions containing the same and process for their preparation
FI943688L (fi)	1995-03-21	Uudet 11-bentsaldoksiimi-17beta-metoksi-27alfa-metoksi-metyyli-estradieenijohdannaiset, menetelmät niiden valmistamiseksi ja näitä sisältävät lääkeaineet
FI944770A7 (fi)	1995-04-13	Neurotensiiniin vaikuttavia substituoituja 1-naftyylipyratsoli-3-karboksiamideja, niiden valmistus ja niitä sisältäviä farmaseuttisia koostumuksia
FI941836A7 (fi)	1994-10-23	3-deoksioligosakkaridit, menetelmiä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
NO20003662D0 (no)	2000-07-17	Syntetiske polysakkarider, fremgangsmÕte for fremstilling derav og farmasøytiske preparater inneholdende slike
IT8921962A0 (it)	1989-10-09	Complessi di inclusione con ciclodestrina, loro preparazione e composizioni farmaceutiche che li contengono
NO960272L (no)	1996-01-23	Oksatiolaner, fremgangsmåte for deres fremstilling og farmasöytiske preparater som inneholder de samme
IT1243389B (it)	1994-06-10	Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono.
ITFI930187A1 (it)	1995-03-30	Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.
FI944751L (fi)	1995-04-12	Heteroaryylipiperidiinejä, menetelmä niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia
ITMI941696A0 (it)	1994-08-04	8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
ITFI930007A1 (it)	1994-07-20	Tiodiazepine, loro processi di preparazione e composizioni farmaceutiche che le contengono
IT1243751B (it)	1994-06-21	Derivati di corticosteroidi, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
ITMI942023A0 (it)	1994-10-04	6-benzil-4-ossopirimidine sostituite, processo per la loro preparazione e composizioni farmaceutiche che le contengono
IT1307846B1 (it)	2001-11-19	L-arabino disaccaridi di antracicline, loro processi di preparazione ecomposizioni farmaceutiche che li contengono.
ITFI920134A1 (it)	1993-12-22	Derivati 7-neopentil xantinici, loro preparazione e composizioni farmaceutiche che li contengono
FI943998A7 (fi)	1995-03-02	Farmaseuttiset koostumukset, jotka sisältävät anionisia pinta-aktiivisia aineita
IT8720179A0 (it)	1987-04-17	2-sulfinil-acetil-1,3-tiazolidine, loro preparazione e composizioni farmaceutiche.
ZA94434B (en)	1994-09-08	Pharmaceutical composition.
ITFI930216A1 (it)	1995-05-03	Derivati tetraciclici diazepinici, loro processi di preparazione e composizioni farmaceutiche che li contengono
IT1307845B1 (it)	2001-11-19	Antracicline disaccaridi sostituite in c-9, loro processi dipreparazione e composizioni farmaceutiche che li contengono.

Legal Events

Date	Code	Title	Description
1996-07-04	0001	Granted
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970929