IT8848172A0 - Impiego di 5ht-3 antagonisti per la preparazione di medicamenti che contrastano gli effetti degli agenti induttori di dipendenza - Google Patents
Impiego di 5ht-3 antagonisti per la preparazione di medicamenti che contrastano gli effetti degli agenti induttori di dipendenzaInfo
- Publication number
- IT8848172A0 IT8848172A0 IT8848172A IT4817288A IT8848172A0 IT 8848172 A0 IT8848172 A0 IT 8848172A0 IT 8848172 A IT8848172 A IT 8848172A IT 4817288 A IT4817288 A IT 4817288A IT 8848172 A0 IT8848172 A0 IT 8848172A0
- Authority
- IT
- Italy
- Prior art keywords
- addiction
- antagonists
- medicines
- contrast
- preparation
- Prior art date
Links
- 206010012335 Dependence Diseases 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000003369 serotonin 5-HT3 receptor antagonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3722959 | 1987-07-11 | ||
| DE3735719 | 1987-10-22 | ||
| CH451087 | 1987-11-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8848172A0 true IT8848172A0 (it) | 1988-07-11 |
| IT1226632B IT1226632B (it) | 1991-01-28 |
Family
ID=27174878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8848172A IT1226632B (it) | 1987-07-11 | 1988-07-11 | Impiego di 5ht-3 antagonisti per la preparazione di medicamenti che contrastano gli effetti degli agenti induttori di dipendenza |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5039680A (it) |
| EP (1) | EP0302008A3 (it) |
| JP (1) | JPS6431729A (it) |
| KR (1) | KR890001537A (it) |
| AT (1) | AT401615B (it) |
| AU (3) | AU618008B2 (it) |
| BE (1) | BE1004835A5 (it) |
| DE (1) | DE3822792C2 (it) |
| DK (1) | DK385388A (it) |
| FR (1) | FR2617713A1 (it) |
| GB (2) | GB2206788B (it) |
| HU (1) | HU206042B (it) |
| IT (1) | IT1226632B (it) |
| MY (1) | MY103536A (it) |
| NL (1) | NL8801733A (it) |
| PH (1) | PH27002A (it) |
| PT (1) | PT87958B (it) |
| SE (1) | SE8802570L (it) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198447A (en) * | 1986-11-21 | 1993-03-30 | Glaxo Group Limited | Medicaments |
| US4948803A (en) * | 1986-11-21 | 1990-08-14 | Glaxo Group Limited | Medicaments for treatment on prevention of withdrawal syndrome |
| GB8627909D0 (en) * | 1986-11-21 | 1986-12-31 | Glaxo Group Ltd | Medicaments |
| DE3822792C2 (de) * | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
| US5166341A (en) * | 1988-07-29 | 1992-11-24 | Dainippon Pharmaceutical Co., Ltd. | 6-amino-1,4-hexahydro-1H-diazepine derivatives |
| NZ230068A (en) * | 1988-07-29 | 1991-07-26 | Dainippon Pharmaceutical Co | Indazole-3-carboxylic acid esters and amides of diaza compounds having 6,7, or 8 ring members: preparatory processes and pharmaceutical compositions |
| GB8820650D0 (en) * | 1988-09-01 | 1988-10-05 | Glaxo Group Ltd | Medicaments |
| US4999382A (en) * | 1988-10-26 | 1991-03-12 | Massachusetts Institute Of Technology | Compositions for treating tobacco withdrawal symptoms and methods for their use |
| US5276050A (en) * | 1989-08-01 | 1994-01-04 | Glaxo Group Limited | Medicaments |
| AU2295792A (en) * | 1991-06-26 | 1993-01-25 | Sepracor, Inc. | Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron |
| JPH05310732A (ja) * | 1992-03-12 | 1993-11-22 | Mitsubishi Kasei Corp | シンノリン−3−カルボン酸誘導体 |
| JP2699794B2 (ja) * | 1992-03-12 | 1998-01-19 | 三菱化学株式会社 | チエノ〔3,2−b〕ピリジン誘導体 |
| US6109269A (en) * | 1999-04-30 | 2000-08-29 | Medtronic, Inc. | Method of treating addiction by brain infusion |
| US6218421B1 (en) * | 1999-07-01 | 2001-04-17 | Smithkline Beecham P.L.C. | Method of promoting smoking cessation |
| US20040092511A1 (en) * | 1999-12-10 | 2004-05-13 | Billstein Stephan Anthony | Pharmaceutical combinations and their use in treating gastrointestinal and abdominal viscera disorders |
| EP1381603A2 (en) | 2000-08-18 | 2004-01-21 | PHARMACIA & UPJOHN COMPANY | Quinuclidine-substituedaryl moieties for treatment of disease ( nicotinic acetylcholine receptor ligands ) |
| WO2002016357A2 (en) | 2000-08-18 | 2002-02-28 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands) |
| US6492385B2 (en) | 2000-08-18 | 2002-12-10 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
| US6500840B2 (en) | 2000-08-21 | 2002-12-31 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
| WO2002015662A2 (en) | 2000-08-21 | 2002-02-28 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic acetylcholine receptor antagonists |
| PE20021019A1 (es) | 2001-04-19 | 2002-11-13 | Upjohn Co | Grupos azabiciclicos sustituidos |
| AR036041A1 (es) * | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen |
| AR036040A1 (es) | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
| US6569887B2 (en) * | 2001-08-24 | 2003-05-27 | Dov Pharmaceuticals Inc. | (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake |
| BR0212123A (pt) * | 2001-08-24 | 2004-07-20 | Upjohn Co | 7-aza[2.2.1]biciclo-heptanos substituìdos com arila para o tratamento de doenças |
| US6562816B2 (en) | 2001-08-24 | 2003-05-13 | Pharmacia & Upjohn Company | Substituted-heteroaryl-7-aza[2.2.1]bicycloheptanes for the treatment of disease |
| WO2003022856A1 (en) * | 2001-09-12 | 2003-03-20 | Pharmacia & Upjohn Company | Substituted 7-aza[2.2.1] bicycloheptanes for the treatment of diseases |
| US6911543B2 (en) | 2001-10-02 | 2005-06-28 | Pfizer Inc. | Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease |
| US6849620B2 (en) | 2001-10-26 | 2005-02-01 | Pfizer Inc | N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease |
| US6919359B2 (en) * | 2001-11-08 | 2005-07-19 | Pfizer Inc | Azabicyclic-substituted-heteroaryl compounds for the treatment of disease |
| JP2005510523A (ja) | 2001-11-09 | 2005-04-21 | ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー | アザ二環式フェニル縮合複素環式化合物、及びα7NACHRリガンドとしての当該化合物の使用 |
| DK1472225T3 (da) | 2002-02-01 | 2010-08-09 | Euro Celtique Sa | 2-Piperazinpyridiner, som er anvendelige til behandling af smerte |
| MXPA04007936A (es) | 2002-02-15 | 2004-11-26 | Upjohn Co | Compuestos de aril-sustituidos para el tratamiento de enfermedades. |
| AU2003217275A1 (en) * | 2002-02-19 | 2003-09-09 | Pharmacia And Upjohn Company | Azabicyclic compounds for the treatment of disease |
| JP2005523288A (ja) * | 2002-02-19 | 2005-08-04 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 疾病治療用の縮合した二環式−n−架橋−複素環式芳香族カルボキサミド |
| WO2003072578A1 (en) * | 2002-02-20 | 2003-09-04 | Pharmacia & Upjohn Company | Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity |
| US6974818B2 (en) * | 2002-03-01 | 2005-12-13 | Euro-Celtique S.A. | 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain |
| US6864261B2 (en) * | 2002-05-02 | 2005-03-08 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| WO2004002983A2 (en) * | 2002-06-28 | 2004-01-08 | Euro-Celtique, S.A. | Therapeutic piperazine derivatives useful for treating pain |
| US7262194B2 (en) * | 2002-07-26 | 2007-08-28 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| US20080081834A1 (en) | 2002-07-31 | 2008-04-03 | Lippa Arnold S | Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders |
| JP2005537297A (ja) * | 2002-08-01 | 2005-12-08 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | アルファ−7nachr活性を有する1h−ピラゾールおよび1h−ピロール−アザビシクロ化合物 |
| US7157462B2 (en) * | 2002-09-24 | 2007-01-02 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| US20040127501A1 (en) * | 2002-09-24 | 2004-07-01 | Zhengming Chen | Therapeutic agents useful for treating pain |
| CA2503786A1 (en) * | 2002-11-01 | 2004-05-13 | Pharmacia & Upjohn Company Llc | Compounds having both alpha7 nicotinic agonist activity and 5ht, antagonist activity for treatment of cns diseases |
| US7582635B2 (en) * | 2002-12-24 | 2009-09-01 | Purdue Pharma, L.P. | Therapeutic agents useful for treating pain |
| TWI287010B (en) * | 2003-06-12 | 2007-09-21 | Euro Celtique Sa | Therapeutic agents useful for treating pain |
| PT1641775E (pt) * | 2003-07-03 | 2009-04-23 | Euro Celtique Sa | Derivados de 2-piridina-alcino úteis para o tratamento da dor |
| DE602004021206D1 (de) * | 2003-07-24 | 2009-07-02 | Euro Celtique Sa | Zur Behandlung oder Vorbeugung von Schmerzen geeignete Heteroaryl-Tetrahydropiperidyl-Verbindungen |
| EP1867644B1 (en) | 2003-07-24 | 2009-05-20 | Euro-Celtique S.A. | Heteroaryl-tetrahydropiperidyl compounds useful for treating or preventing pain |
| HRP20090404T1 (hr) * | 2003-07-24 | 2009-08-31 | Euro-Celtique S.A. | Spojevi piperidina i farmaceutski sastavi koji ih sadržavaju |
| PT1648880E (pt) * | 2003-08-01 | 2010-04-26 | Euro Celtique Sa | Agentes terapêuticos úteis para o tratamento da dor |
| ES2317052T3 (es) * | 2003-09-22 | 2009-04-16 | Euro-Celtique S.A. | Agentes terapeuticos utiles para el tratamiento del dolor. |
| PL1664041T3 (pl) * | 2003-09-22 | 2008-12-31 | Euro Celtique Sa | Przydatne do leczenia bólu związki fenylowo-karboksyamidowe |
| NZ548169A (en) * | 2003-12-30 | 2009-04-30 | Euro Celtique Sa | Piperazines useful for treating pain |
| US20070043100A1 (en) | 2005-08-16 | 2007-02-22 | Hagen Eric J | Novel polymorphs of azabicyclohexane |
| US20060100263A1 (en) * | 2004-11-05 | 2006-05-11 | Anthony Basile | Antipyretic compositions and methods |
| EP1915146A4 (en) | 2005-07-27 | 2010-06-02 | Dov Pharmaceutical Inc | NOVEL 1-ARYL-3-AZABICYCLO [3.1.0] HEXANEES. PREPARATION AND USE FOR THE TREATMENT OF NEUROPSYCHIATRIC DISEASES |
| US20080045725A1 (en) * | 2006-04-28 | 2008-02-21 | Murry Jerry A | Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane |
| US8138377B2 (en) * | 2006-11-07 | 2012-03-20 | Dov Pharmaceutical, Inc. | Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use |
| JP5372913B2 (ja) * | 2007-04-27 | 2013-12-18 | パーデュー、ファーマ、リミテッド、パートナーシップ | 疼痛治療に有効な治療薬 |
| US9133159B2 (en) | 2007-06-06 | 2015-09-15 | Neurovance, Inc. | 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments |
| US20090069374A1 (en) * | 2007-06-06 | 2009-03-12 | Phil Skolnick | Novel 1-Heteroaryl-3-Azabicyclo[3.1.0]Hexanes, Methods For Their Preparation And Their Use As Medicaments |
| US8697722B2 (en) * | 2007-11-02 | 2014-04-15 | Sri International | Nicotinic acetylcholine receptor modulators |
| EP2523562B1 (en) * | 2010-01-11 | 2019-01-02 | Astraea Therapeutics, LLC | Nicotinic acetylcholine receptor modulators |
| GB201106817D0 (en) | 2011-04-21 | 2011-06-01 | Astex Therapeutics Ltd | New compound |
| US20140206740A1 (en) | 2011-07-30 | 2014-07-24 | Neurovance, Inc. | Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters |
| US9980973B2 (en) | 2012-10-19 | 2018-05-29 | Astex Therapeutics Limited | Bicyclic heterocycle compounds and their uses in therapy |
| GB201218862D0 (en) | 2012-10-19 | 2012-12-05 | Astex Therapeutics Ltd | Bicyclic heterocycle compounds and their uses in therapy |
| GB201218850D0 (en) | 2012-10-19 | 2012-12-05 | Astex Therapeutics Ltd | Bicyclic heterocycle compounds and their uses in therapy |
| GB201218864D0 (en) | 2012-10-19 | 2012-12-05 | Astex Therapeutics Ltd | Bicyclic heterocycle compounds and their uses in therapy |
| LT3083616T (lt) | 2013-12-20 | 2021-09-10 | Astex Therapeutics Limited | Bicikinių heterociklų junginiai ir jų panaudojimas terapijoje |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL59004A0 (en) * | 1978-12-30 | 1980-03-31 | Beecham Group Ltd | Substituted benzamides their preparation and pharmaceutical compositions containing them |
| BE897117A (fr) * | 1982-06-29 | 1983-12-23 | Sandoz Sa | Nouveaux derives de la piperidine leur preparation et leur utilisation comme medicaments |
| FI74707C (fi) * | 1982-06-29 | 1988-03-10 | Sandoz Ag | Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror. |
| DE3429830A1 (de) * | 1983-08-26 | 1985-03-07 | Sandoz-Patent-GmbH, 7850 Lörrach | Automatische carbonsaeure- und sulfonsaeureester oder -amide |
| DE3445377A1 (de) * | 1983-12-23 | 1985-07-04 | Sandoz-Patent-GmbH, 7850 Lörrach | Carbocylische und heterocyclische carbonsaeureester und -amide von ueberbrueckten und nicht ueberbrueckten cyclischen stickstoffhaltigen aminen oder alkoholen |
| IL74165A (en) * | 1984-01-25 | 1988-11-15 | Glaxo Group Ltd | 1,2,3,9-tetrahydro-3-(1h-imidazole-1-yl methyl)-4h-carbazol-4-one compounds,their preparation and pharmaceutical compositions containing them |
| EP0385517B1 (en) * | 1985-03-14 | 1993-04-14 | BEECHAM GROUP plc | Medicaments for the treatment of emesis |
| EP0200444B1 (en) * | 1985-04-27 | 1992-11-11 | Beecham Group Plc | Azabicyclononyl-indazole-carboxamide having 5-ht antagonist activity |
| GR861128B (en) * | 1985-05-06 | 1986-08-26 | Sandoz Ag | New use of dopamine agonists |
| GB8516083D0 (en) * | 1985-06-25 | 1985-07-31 | Glaxo Group Ltd | Heterocyclic compounds |
| GB8520616D0 (en) * | 1985-08-16 | 1985-09-25 | Beecham Group Plc | Compounds |
| GB8701494D0 (en) * | 1987-01-23 | 1987-02-25 | Glaxo Group Ltd | Chemical compounds |
| GB8627909D0 (en) * | 1986-11-21 | 1986-12-31 | Glaxo Group Ltd | Medicaments |
| US4948803A (en) * | 1986-11-21 | 1990-08-14 | Glaxo Group Limited | Medicaments for treatment on prevention of withdrawal syndrome |
| GR871809B (en) * | 1986-11-28 | 1988-03-07 | Glaxo Group Ltd | Process for the preparation of tricyclic ketones |
| GB8630080D0 (en) * | 1986-12-17 | 1987-01-28 | Glaxo Group Ltd | Medicaments |
| DE3822792C2 (de) * | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
| ES2060655T3 (es) * | 1987-09-03 | 1994-12-01 | Glaxo Group Ltd | Derivados de lactamas. |
| IL87674A (en) * | 1987-09-08 | 1993-08-18 | Lilly Co Eli | Azabicycloalkyl esters and amides of heterocyclic acids, their preparation and pharmaceutical compositions containing them |
| GB8723157D0 (en) * | 1987-10-02 | 1987-11-04 | Beecham Group Plc | Compounds |
| NZ227229A (en) * | 1987-12-10 | 1991-03-26 | Duphar Int Res | Indole derivatives and pharmaceutical compositions |
| US5116984A (en) * | 1988-04-07 | 1992-05-26 | Glaxo Group Limited | Imidazole derivatives |
-
1988
- 1988-07-06 DE DE3822792A patent/DE3822792C2/de not_active Expired - Fee Related
- 1988-07-07 EP EP19880810470 patent/EP0302008A3/en not_active Withdrawn
- 1988-07-08 NL NL8801733A patent/NL8801733A/nl not_active Application Discontinuation
- 1988-07-08 PT PT87958A patent/PT87958B/pt not_active IP Right Cessation
- 1988-07-08 FR FR8809350A patent/FR2617713A1/fr active Granted
- 1988-07-08 DK DK385388A patent/DK385388A/da not_active Application Discontinuation
- 1988-07-08 SE SE8802570A patent/SE8802570L/xx not_active Application Discontinuation
- 1988-07-08 AT AT0177688A patent/AT401615B/de not_active IP Right Cessation
- 1988-07-08 MY MYPI88000755A patent/MY103536A/en unknown
- 1988-07-08 GB GB8816298A patent/GB2206788B/en not_active Expired - Lifetime
- 1988-07-08 HU HU883610A patent/HU206042B/hu not_active IP Right Cessation
- 1988-07-09 JP JP63171704A patent/JPS6431729A/ja active Pending
- 1988-07-09 KR KR1019880008589A patent/KR890001537A/ko not_active Ceased
- 1988-07-11 AU AU18920/88A patent/AU618008B2/en not_active Ceased
- 1988-07-11 IT IT8848172A patent/IT1226632B/it active
- 1988-07-11 BE BE8800802A patent/BE1004835A5/fr not_active IP Right Cessation
- 1988-07-11 PH PH37205A patent/PH27002A/en unknown
-
1990
- 1990-01-19 US US07/467,598 patent/US5039680A/en not_active Expired - Fee Related
-
1991
- 1991-03-05 GB GB9104598A patent/GB2240475B/en not_active Expired - Lifetime
- 1991-10-07 AU AU85628/91A patent/AU633762B2/en not_active Ceased
- 1991-10-07 AU AU85630/91A patent/AU643075B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DK385388A (da) | 1989-01-12 |
| PT87958B (pt) | 1995-03-01 |
| BE1004835A5 (fr) | 1993-02-09 |
| MY103536A (en) | 1993-07-31 |
| PT87958A (pt) | 1989-06-30 |
| GB2206788B (en) | 1992-03-25 |
| AT401615B (de) | 1996-10-25 |
| AU643075B2 (en) | 1993-11-04 |
| US5039680A (en) | 1991-08-13 |
| GB8816298D0 (en) | 1988-08-10 |
| EP0302008A3 (en) | 1992-12-23 |
| JPS6431729A (en) | 1989-02-02 |
| GB2206788A (en) | 1989-01-18 |
| NL8801733A (nl) | 1989-02-01 |
| AU8563091A (en) | 1991-12-12 |
| FR2617713A1 (fr) | 1989-01-13 |
| AU1892088A (en) | 1989-01-12 |
| GB9104598D0 (en) | 1991-04-17 |
| AU8562891A (en) | 1991-12-05 |
| DK385388D0 (da) | 1988-07-08 |
| AU618008B2 (en) | 1991-12-12 |
| KR890001537A (ko) | 1989-03-27 |
| DE3822792C2 (de) | 1997-11-27 |
| IT1226632B (it) | 1991-01-28 |
| GB2240475A (en) | 1991-08-07 |
| HUT50038A (en) | 1989-12-28 |
| GB2240475B (en) | 1992-03-18 |
| HU206042B (en) | 1992-08-28 |
| AU633762B2 (en) | 1993-02-04 |
| PH27002A (en) | 1993-02-01 |
| DE3822792A1 (de) | 1989-01-19 |
| FR2617713B1 (it) | 1994-08-19 |
| SE8802570D0 (sv) | 1988-07-08 |
| EP0302008A2 (en) | 1989-02-01 |
| SE8802570L (sv) | 1989-03-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT8848172A0 (it) | Impiego di 5ht-3 antagonisti per la preparazione di medicamenti che contrastano gli effetti degli agenti induttori di dipendenza | |
| IT8667332A0 (it) | Dispositivo per l erogazione ddi farmaci | |
| IT1219402B (it) | Dispensatore di farmaci | |
| IT8267184A0 (it) | Bendaggio per la somministrazione di medicamenti | |
| DK237884D0 (da) | Farmaceutisk praeparat | |
| FR2636532B1 (fr) | Compositions pharmaceutiques | |
| DK299089D0 (da) | Anvendelse af prostaglandiner til fremstilling af laegemidler | |
| DK530888D0 (da) | Leukotrien -ltd4- og - ltb4-antagonister | |
| IT1223799B (it) | Forma di dosaggio per la somministrazione di diltiazem | |
| DK435688D0 (da) | Farmaceutiske midler | |
| DK109887A (da) | Farmaceutisk praeparat indeholdende antistoffer | |
| DK58983D0 (da) | Farmaceutisk praeparat | |
| DK495089A (da) | Anvendelse af thromboxan a2-receptor-antagonister til fremstilling af laegemidler | |
| IT1219250B (it) | Procedimento per la preparazione di idrocarburi | |
| IT1177485B (it) | Composizioni farmaceutiche antitumorali e procedimento per la loro preparazione | |
| DK504187A (da) | Farmaceutisk praeparat indeholdende mindst en lipidregulator | |
| IT1219556B (it) | Cartuccia per la preparazione di sandwich | |
| IT8719009A0 (it) | Composti antagonisti di recettori -h2 e procedimento per la loro preparazione. | |
| DK37589A (da) | Farmaceutisk praeparat for 4-aroylimidazol-2-oner | |
| FR2618676B1 (fr) | Compositions pharmaceutiques antivirales | |
| IT8848410A0 (it) | Procedimento per la preparazione di calcestruzzo proiettato | |
| IT1170255B (it) | Composizione farmaceutica per la somministrazione orale di calcitonina | |
| IT8721455A0 (it) | Composizioni farmaceutiche per la terapia di stati fisiopatologici ad accresciuto catabolismo proteico. | |
| FR2550093B1 (fr) | Compositions pharmaceutiques contenant de la quinine | |
| IT8720229A0 (it) | Composizioni farmaceutiche adattivita' spasmolitica contenente come principio attio idanpramina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970623 |