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IT202200016647A1 - PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF HPV - Google Patents

PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF HPV Download PDF

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Publication number
IT202200016647A1
IT202200016647A1 IT102022000016647A IT202200016647A IT202200016647A1 IT 202200016647 A1 IT202200016647 A1 IT 202200016647A1 IT 102022000016647 A IT102022000016647 A IT 102022000016647A IT 202200016647 A IT202200016647 A IT 202200016647A IT 202200016647 A1 IT202200016647 A1 IT 202200016647A1
Authority
IT
Italy
Prior art keywords
hpv
prevention
treatment
pharmaceutical composition
pharmaceutical
Prior art date
Application number
IT102022000016647A
Other languages
Italian (it)
Inventor
Roberto Becelli
Marco Federico De
Fabio Altieri
Original Assignee
Np1 Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Np1 Srl filed Critical Np1 Srl
Priority to IT102022000016647A priority Critical patent/IT202200016647A1/en
Priority to CN202380070693.9A priority patent/CN119997946A/en
Priority to EP23765574.1A priority patent/EP4565223A1/en
Priority to PCT/IT2023/050191 priority patent/WO2024028914A1/en
Publication of IT202200016647A1 publication Critical patent/IT202200016647A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT102022000016647A 2022-08-04 2022-08-04 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF HPV IT202200016647A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT102022000016647A IT202200016647A1 (en) 2022-08-04 2022-08-04 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF HPV
CN202380070693.9A CN119997946A (en) 2022-08-04 2023-08-03 Pharmaceutical compositions for treating and preventing HPV
EP23765574.1A EP4565223A1 (en) 2022-08-04 2023-08-03 Pharmaceutical composition for the treatment and prevention of hpv
PCT/IT2023/050191 WO2024028914A1 (en) 2022-08-04 2023-08-03 Pharmaceutical composition for the treatment and prevention of hpv

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102022000016647A IT202200016647A1 (en) 2022-08-04 2022-08-04 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF HPV

Publications (1)

Publication Number Publication Date
IT202200016647A1 true IT202200016647A1 (en) 2024-02-04

Family

ID=83505674

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102022000016647A IT202200016647A1 (en) 2022-08-04 2022-08-04 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF HPV

Country Status (4)

Country Link
EP (1) EP4565223A1 (en)
CN (1) CN119997946A (en)
IT (1) IT202200016647A1 (en)
WO (1) WO2024028914A1 (en)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1879613A (en) * 2005-06-16 2006-12-20 广州汉方现代中药研究开发有限公司 Medicine containing galangin and preparation method thereof
US20080221029A1 (en) * 2002-10-31 2008-09-11 Regents Of The University Of Colorado Methods for treatment of thiol-containing compound deficient conditions
WO2009023059A2 (en) * 2007-06-01 2009-02-19 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
US20120269818A1 (en) * 2011-04-25 2012-10-25 Ozbun Michelle A Methods for treating infection by hpv
US20190117616A1 (en) * 2017-10-20 2019-04-25 National Tsing Hua University Method for regulating kdm4a, kdm4b, and kdm4c activity
CN110934862A (en) * 2020-01-02 2020-03-31 四川农业大学 Application of kaempferol in anti-pseudorabies virus medicine
CN111995608A (en) * 2020-08-31 2020-11-27 厦门一三九生物科技有限公司 Antiviral compound containing luteolin and preparation method thereof
US20210299151A1 (en) * 2018-12-11 2021-09-30 Glyciome, Llc Topical, isotonic compositions for genital use
US11311563B2 (en) * 2017-08-28 2022-04-26 Global Biolife Inc. Method and composition for preventing and treating viral infections

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080221029A1 (en) * 2002-10-31 2008-09-11 Regents Of The University Of Colorado Methods for treatment of thiol-containing compound deficient conditions
CN1879613A (en) * 2005-06-16 2006-12-20 广州汉方现代中药研究开发有限公司 Medicine containing galangin and preparation method thereof
WO2009023059A2 (en) * 2007-06-01 2009-02-19 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
US20120269818A1 (en) * 2011-04-25 2012-10-25 Ozbun Michelle A Methods for treating infection by hpv
US11311563B2 (en) * 2017-08-28 2022-04-26 Global Biolife Inc. Method and composition for preventing and treating viral infections
US20190117616A1 (en) * 2017-10-20 2019-04-25 National Tsing Hua University Method for regulating kdm4a, kdm4b, and kdm4c activity
US20210299151A1 (en) * 2018-12-11 2021-09-30 Glyciome, Llc Topical, isotonic compositions for genital use
CN110934862A (en) * 2020-01-02 2020-03-31 四川农业大学 Application of kaempferol in anti-pseudorabies virus medicine
CN111995608A (en) * 2020-08-31 2020-11-27 厦门一三九生物科技有限公司 Antiviral compound containing luteolin and preparation method thereof

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* Cited by examiner, † Cited by third party
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CARDONA FANDRES-LACUEVA CTULIPANI STINAHONES FJQUEIPO-ORTUNO MI: "Benefits of polyphenols on gut microbiota and implications in human health", J NUTR BIOCHEM., vol. 24, no. 8, pages 1415 - 22, XP028675333, DOI: 10.1016/j.jnutbio.2013.05.001
CHEN S -M: "Inductive effects of galangin on apotosis of human papilloma virus positive cervical cancer cells", CHINESE TRADITIONAL AND HERBAL DRUGS 20170312 EDITORIAL OFFICE OF CHINESE TRADITIONAL AND CHN, vol. 48, no. 5, 12 March 2017 (2017-03-12), pages 941 - 945, ISSN: 0253-2670 *
CHERRY JONATHAN J. ET AL: "Structure Based Identification and Characterization of Flavonoids That Disrupt Human Papillomavirus-16 E6 Function", PLOS ONE, vol. 8, no. 12, 1 December 2013 (2013-12-01), pages e84506, XP093019866, Retrieved from the Internet <URL:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0084506&type=printable> DOI: 10.1371/journal.pone.0084506 *
CHUNG-HSIANG YUAN ET AL: "Small molecule inhibitors of the HPV16-E6 interaction with caspase 8", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ELSEVIER, AMSTERDAM NL, vol. 22, no. 5, 5 December 2011 (2011-12-05), pages 2125 - 2129, XP028459469, ISSN: 0960-894X, [retrieved on 20120110], DOI: 10.1016/J.BMCL.2011.12.145 *
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KOPUSTINSKIENE DMJAKSTAS VSAVICKAS ABERNATONIENE J.: "Flavonoids as Anticancer Agents", NUTRIENTS, vol. 12, no. 2, 12 February 2020 (2020-02-12), pages 457
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LANSKY EPHARRISON GFROOM PJIANG WG: "Pomegranate (Punica granatum) pure chemicals show possible synergistic inhibition of human PC-3 prostate cancer cell invasion across Matrigel", INVESTIGATIONAL NEW DRUGS, vol. 23, 2005, pages 121 - 122, XP019206067, DOI: 10.1007/s10637-005-5856-7
LERI MSCUTO MONTARIO MLCALABRESE VCALABRESE EJBUCCIANTINI MSTEFANI M: "Healthy Effects of Plant Polyphenols: Molecular Mechanisms", INT J MOL SCI., vol. 21, no. 4, 13 February 2020 (2020-02-13), pages 1250
LU YJIANG FJIANG HWU KZHENG XCAI YKATAKOWSKI MCHOPP MTO SST: "Gallic acid suppresses cell viability, proliferation, invasion and angiogenesis in human glioma cells.", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 641, no. 2-3, 2010, pages 102 - 107, XP027112359
SCHERER WF, SYVERTON JT, GEY GO.: ""Studies on the propagation in vitro of poliomyelitis viruses. IV. Viral multiplication in a stable strain of human malignant epithelial cells (strain HeLa) derived from an epidermoid carcinoma of the cervix". ", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 97, no. 5, 1953, pages 695 - 710, XP055047777, DOI: 10.1084/jem.97.5.695
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Also Published As

Publication number Publication date
WO2024028914A9 (en) 2024-06-27
EP4565223A1 (en) 2025-06-11
WO2024028914A1 (en) 2024-02-08
CN119997946A (en) 2025-05-13

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