IT1311989B1 - Procedimento per isolare cellule fetali presenti nel sangue perifericomaterno. - Google Patents
Procedimento per isolare cellule fetali presenti nel sangue perifericomaterno.Info
- Publication number
- IT1311989B1 IT1311989B1 IT1999MI000652A ITMI990652A IT1311989B1 IT 1311989 B1 IT1311989 B1 IT 1311989B1 IT 1999MI000652 A IT1999MI000652 A IT 1999MI000652A IT MI990652 A ITMI990652 A IT MI990652A IT 1311989 B1 IT1311989 B1 IT 1311989B1
- Authority
- IT
- Italy
- Prior art keywords
- fetal cells
- procedure
- peripheral blood
- cells present
- isolating fetal
- Prior art date
Links
- 230000001605 fetal effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 210000005259 peripheral blood Anatomy 0.000 title 1
- 239000011886 peripheral blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 230000008774 maternal effect Effects 0.000 abstract 2
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 238000000432 density-gradient centrifugation Methods 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 238000011835 investigation Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 230000035935 pregnancy Effects 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI000652A IT1311989B1 (it) | 1999-03-30 | 1999-03-30 | Procedimento per isolare cellule fetali presenti nel sangue perifericomaterno. |
| PCT/EP2000/002718 WO2000060351A1 (en) | 1999-03-30 | 2000-03-28 | Method for the separation of fetal cells from the maternal peripheral blood |
| DE60006505T DE60006505T2 (de) | 1999-03-30 | 2000-03-28 | Verfahren zu trennung fötaler zellen aus maternalem blut |
| AT00912653T ATE254282T1 (de) | 1999-03-30 | 2000-03-28 | Verfahren zu trennung fötaler zellen aus maternalem blut |
| AU34324/00A AU3432400A (en) | 1999-03-30 | 2000-03-28 | Method for the separation of fetal cells from the maternal peripheral blood |
| EP00912653A EP1166108B1 (en) | 1999-03-30 | 2000-03-28 | Method for the separation of fetal cells from the maternal peripheral blood |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI000652A IT1311989B1 (it) | 1999-03-30 | 1999-03-30 | Procedimento per isolare cellule fetali presenti nel sangue perifericomaterno. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITMI990652A1 ITMI990652A1 (it) | 2000-09-30 |
| IT1311989B1 true IT1311989B1 (it) | 2002-03-22 |
Family
ID=11382509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT1999MI000652A IT1311989B1 (it) | 1999-03-30 | 1999-03-30 | Procedimento per isolare cellule fetali presenti nel sangue perifericomaterno. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1166108B1 (it) |
| AT (1) | ATE254282T1 (it) |
| AU (1) | AU3432400A (it) |
| DE (1) | DE60006505T2 (it) |
| IT (1) | IT1311989B1 (it) |
| WO (1) | WO2000060351A1 (it) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007050986A1 (en) * | 2005-10-27 | 2007-05-03 | Neil Duffy | Cell separation method and apparatus |
| US8048678B2 (en) | 2005-10-27 | 2011-11-01 | Ecw Therapeutics, Inc. | Cell separation method and apparatus |
| GB0616045D0 (en) * | 2006-08-11 | 2006-09-20 | Univ Bristol | Blood cell separation |
| US20150299657A1 (en) * | 2014-04-16 | 2015-10-22 | General Electric Company | Gamma stabilized dextran solutions and methods of use |
| GB201306810D0 (en) | 2013-04-15 | 2013-05-29 | Cells4Life Group Llp | Methods of cell separation |
| GB2525202A (en) * | 2014-04-15 | 2015-10-21 | Cells4Life Group Llp | Methods of cell separation |
| US20160130553A1 (en) | 2014-05-15 | 2016-05-12 | Kellbenx Incorporated | PREPARATION OF FETAL NUCLEATED RED BLOOD CELLS (NRBCs) FOR DIAGNOSTIC TESTING |
| US12202890B1 (en) | 2014-11-07 | 2025-01-21 | Kellbenx Incorporated | Antibodies for detection and enrichment of fetal cells and their use |
| WO2016178931A1 (en) * | 2015-05-01 | 2016-11-10 | Mesotex, Inc. | Process for separating nucleated cells from non-nucleated red blood cells |
| US20190153392A1 (en) * | 2016-04-07 | 2019-05-23 | Mesotex, Inc. | Process for isolating nucleated cells and nucleated cell populations and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1057254A (en) | 1976-05-14 | 1979-06-26 | Baxter Travenol Laboratories | Disposable centrifugal blood processing system |
| FR2481614A1 (fr) | 1980-05-05 | 1981-11-06 | Inst Medical Sciences | Procede, dispositif et appareil pour separer par centrifugation les plaquettes du sang |
| US4424132A (en) | 1981-02-05 | 1984-01-03 | Asahi Kasei Kogyo Kabushiki Kaisha | Apparatus and method for separating blood components |
| US5489386A (en) * | 1994-01-31 | 1996-02-06 | Applied Imaging | Density gradient medium for the separation of cells |
| US5432054A (en) * | 1994-01-31 | 1995-07-11 | Applied Imaging | Method for separating rare cells from a population of cells |
| US5663051A (en) * | 1994-08-31 | 1997-09-02 | Activated Cell Therapy, Inc. | Separation apparatus and method |
| US5662813A (en) * | 1994-10-21 | 1997-09-02 | Bioseparations, Inc. | Method for separation of nucleated fetal erythrocytes from maternal blood samples |
| IT1295939B1 (it) | 1997-10-31 | 1999-05-28 | Giammaria Sitar | Dispositivo e metodo per la separazione di cellule umane od animali aventi densita' diverse da dispersioni cellulari che le contengono |
-
1999
- 1999-03-30 IT IT1999MI000652A patent/IT1311989B1/it active
-
2000
- 2000-03-28 WO PCT/EP2000/002718 patent/WO2000060351A1/en not_active Ceased
- 2000-03-28 EP EP00912653A patent/EP1166108B1/en not_active Expired - Lifetime
- 2000-03-28 AU AU34324/00A patent/AU3432400A/en not_active Abandoned
- 2000-03-28 AT AT00912653T patent/ATE254282T1/de not_active IP Right Cessation
- 2000-03-28 DE DE60006505T patent/DE60006505T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000060351A1 (en) | 2000-10-12 |
| EP1166108B1 (en) | 2003-11-12 |
| AU3432400A (en) | 2000-10-23 |
| ITMI990652A1 (it) | 2000-09-30 |
| DE60006505T2 (de) | 2004-08-05 |
| ATE254282T1 (de) | 2003-11-15 |
| DE60006505D1 (de) | 2003-12-18 |
| EP1166108A1 (en) | 2002-01-02 |
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