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IT1302264B1 - Derivati a struttura n-acil vanillinamidica in grado di attivare irecettori periferici dei cannabinoidi - Google Patents

Derivati a struttura n-acil vanillinamidica in grado di attivare irecettori periferici dei cannabinoidi

Info

Publication number
IT1302264B1
IT1302264B1 IT1998MI002064A ITMI982064A IT1302264B1 IT 1302264 B1 IT1302264 B1 IT 1302264B1 IT 1998MI002064 A IT1998MI002064 A IT 1998MI002064A IT MI982064 A ITMI982064 A IT MI982064A IT 1302264 B1 IT1302264 B1 IT 1302264B1
Authority
IT
Italy
Prior art keywords
cannabinoids
derivatives
ireceptors
vanillyamide
acyl
Prior art date
Application number
IT1998MI002064A
Other languages
English (en)
Inventor
Tiziana Bisogno
Valle Francesco Della
Petrocellis Luciano De
Marzo Vincenzo Di
Gabriele Marcolongo
Dominique Melck
Original Assignee
Innovet Italia Srl
Consiglio Nazionale Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innovet Italia Srl, Consiglio Nazionale Ricerche filed Critical Innovet Italia Srl
Priority to IT1998MI002064A priority Critical patent/IT1302264B1/it
Priority to AU60860/99A priority patent/AU6086099A/en
Priority to DE69904490T priority patent/DE69904490T2/de
Priority to EP99947394A priority patent/EP1115392B1/en
Priority to AT99947394T priority patent/ATE229330T1/de
Priority to PCT/EP1999/006980 priority patent/WO2000016756A2/en
Priority to ES99947394T priority patent/ES2189489T3/es
Publication of ITMI982064A1 publication Critical patent/ITMI982064A1/it
Application granted granted Critical
Publication of IT1302264B1 publication Critical patent/IT1302264B1/it
Priority to US10/949,322 priority patent/US7244767B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
IT1998MI002064A 1998-09-24 1998-09-24 Derivati a struttura n-acil vanillinamidica in grado di attivare irecettori periferici dei cannabinoidi IT1302264B1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT1998MI002064A IT1302264B1 (it) 1998-09-24 1998-09-24 Derivati a struttura n-acil vanillinamidica in grado di attivare irecettori periferici dei cannabinoidi
AU60860/99A AU6086099A (en) 1998-09-24 1999-09-21 N-acylvanillinamide derivatives capable of activating peripheral cannabinoid receptors
DE69904490T DE69904490T2 (de) 1998-09-24 1999-09-21 Verwendung von n-acylvanillinamid-derivaten als agonisten der peripheren cannabinoid-cb1-rezeptoren
EP99947394A EP1115392B1 (en) 1998-09-24 1999-09-21 Use of n-acylvanillinamide derivatives as agonists of peripheral cannabinoid cb1 receptors
AT99947394T ATE229330T1 (de) 1998-09-24 1999-09-21 Verwendung von n-acylvanillinamid-derivaten als agonisten der peripheren cannabinoid-cb1- rezeptoren
PCT/EP1999/006980 WO2000016756A2 (en) 1998-09-24 1999-09-21 Use of n-acylvanillinamide derivatives as agonists of peripheral cannabinoid cb1 receptors
ES99947394T ES2189489T3 (es) 1998-09-24 1999-09-21 Uso de derivados n-acilvainillinamidicos como agonistas de receptores cb1 perifericos de cannabinoides.
US10/949,322 US7244767B2 (en) 1998-09-24 2004-09-27 N-acylvanillinamide derivatives capable of activating peripheral cannabinoid receptors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002064A IT1302264B1 (it) 1998-09-24 1998-09-24 Derivati a struttura n-acil vanillinamidica in grado di attivare irecettori periferici dei cannabinoidi

Publications (2)

Publication Number Publication Date
ITMI982064A1 ITMI982064A1 (it) 2000-03-24
IT1302264B1 true IT1302264B1 (it) 2000-09-05

Family

ID=11380754

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998MI002064A IT1302264B1 (it) 1998-09-24 1998-09-24 Derivati a struttura n-acil vanillinamidica in grado di attivare irecettori periferici dei cannabinoidi

Country Status (8)

Country Link
US (1) US7244767B2 (it)
EP (1) EP1115392B1 (it)
AT (1) ATE229330T1 (it)
AU (1) AU6086099A (it)
DE (1) DE69904490T2 (it)
ES (1) ES2189489T3 (it)
IT (1) IT1302264B1 (it)
WO (1) WO2000016756A2 (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6864285B1 (en) 1999-07-07 2005-03-08 Innovet Italia S.R.L. Covalent derivatives of alkanolamides of monocarboxylic and dicarboxylic acids functionally active on the CB2 cannabinoid receptor
WO2001085151A2 (en) * 2000-05-08 2001-11-15 Psoriasis Research Institute Chimeric animal model and treatment of psoriasis
ES2174716B1 (es) * 2000-07-28 2004-08-01 Universidad Complutense De Madrid Nuevos derivados de acido araquidonico con afinidad por el transportador de anandamida.
US8449908B2 (en) 2000-12-22 2013-05-28 Alltranz, Llc Transdermal delivery of cannabidiol
TWI239942B (en) 2001-06-11 2005-09-21 Dainippon Pharmaceutical Co N-arylphenylacetamide derivative and pharmaceutical composition containing the same
ATE406867T1 (de) * 2001-07-18 2008-09-15 Unilever Nv Zusammensetzungen für die behandlung von haaren und/oder kopfhaut
WO2003061699A1 (fr) * 2001-12-27 2003-07-31 Japan Tobacco, Inc. Remedes pour affections allergiques
EP1487436A4 (en) 2002-03-08 2009-06-03 Signal Pharm Inc POLYTHERAPY FOR TREATING, PREVENTING OR MANAGING PROLIFERATIVE DISORDERS AND CANCERS
JP2004182674A (ja) * 2002-12-05 2004-07-02 Kureha Chem Ind Co Ltd バニリル脂肪酸アミドを含む抗腫瘍医薬組成物
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
ITMI20041566A1 (it) * 2004-07-30 2004-10-30 Indena Spa "trpv1 agonisti, formulazioni che li contengono e loro usi"
DK2176208T3 (en) 2007-07-30 2015-04-27 Zynerba Pharmaceuticals Inc Prodrugs of cannabidiol, compositions containing prodrugs of cannabidiol and methods of use thereof
PL2796129T3 (pl) 2009-09-07 2015-11-30 Epitech Group S P A Kompozycja zawierająca palmitoiloetanoloamid poddany ultramikronizacji
ES2362769B1 (es) * 2009-12-24 2012-05-22 Fundació Imim Derivados de amida de ácidos grasos con anfetaminas para el tratamiento de desórdenes alimenticios.
PT2455066T (pt) * 2010-11-08 2018-12-06 Epitech Group S P A Preparação farmacológica para utilização tópica contendo n-palmitoil-vanilamida
CN105612168A (zh) * 2013-11-14 2016-05-25 浙江海正药业股份有限公司 一种二糖中间体及其合成方法
US20190290609A1 (en) * 2014-03-19 2019-09-26 Epitech Group S.P.A. Pharmaceutical composition comprising palmitoylethanolamide and l-acetylcarnitine
ES2575231B1 (es) * 2014-11-24 2017-04-06 Fundación Pública Andaluza Para La Investigación De Málaga En Biomedicina Y Salud (Fimabis) Amidas de ácidos grasos para la prevención y/o tratamiento de la esteatohepatitis.
EP3417846A1 (en) * 2017-06-19 2018-12-26 Gifar Srl Food and/or nutraceutical composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3156240B2 (ja) * 1991-03-20 2001-04-16 小川香料株式会社 カプサイシノイド配糖体
AU658188B2 (en) 1991-05-20 1995-04-06 Tsumura & Co. Phellodendrine analogs and allergy type IV suppressor containing the same as active ingredient
IT1271266B (it) * 1994-12-14 1997-05-27 Valle Francesco Della Impiego terapeutico di ammidi di acidi mono e bicarbossilici con amminoalcoli,selettivamente attive sul recettore periferico dei cannabinoidi
JPH1025237A (ja) * 1996-07-10 1998-01-27 Kanebo Ltd 外用組成物

Also Published As

Publication number Publication date
WO2000016756A2 (en) 2000-03-30
ES2189489T3 (es) 2003-07-01
ITMI982064A1 (it) 2000-03-24
WO2000016756A3 (en) 2000-09-08
DE69904490T2 (de) 2003-10-30
EP1115392A2 (en) 2001-07-18
EP1115392B1 (en) 2002-12-11
ATE229330T1 (de) 2002-12-15
AU6086099A (en) 2000-04-10
US7244767B2 (en) 2007-07-17
US20050065216A1 (en) 2005-03-24
DE69904490D1 (de) 2003-01-23

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