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IT1302125B1 - Composizione ad attivita' antiossidante ed antiproliferativacomprendente una carnitina ed un carotenoide - Google Patents

Composizione ad attivita' antiossidante ed antiproliferativacomprendente una carnitina ed un carotenoide

Info

Publication number
IT1302125B1
IT1302125B1 IT1998RM000516A ITRM980516A IT1302125B1 IT 1302125 B1 IT1302125 B1 IT 1302125B1 IT 1998RM000516 A IT1998RM000516 A IT 1998RM000516A IT RM980516 A ITRM980516 A IT RM980516A IT 1302125 B1 IT1302125 B1 IT 1302125B1
Authority
IT
Italy
Prior art keywords
carotenoid
carnitine
antioxidant
composition
antiproliferative activity
Prior art date
Application number
IT1998RM000516A
Other languages
English (en)
Inventor
Claudio Cavazza
Original Assignee
Sigma Tau Healthscience Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Healthscience Spa filed Critical Sigma Tau Healthscience Spa
Publication of ITRM980516A0 publication Critical patent/ITRM980516A0/it
Priority to IT1998RM000516A priority Critical patent/IT1302125B1/it
Priority to HU0102807A priority patent/HUP0102807A2/hu
Priority to SK125-2001A priority patent/SK1252001A3/sk
Priority to AU50641/99A priority patent/AU5064199A/en
Priority to EP99935044A priority patent/EP1102584A2/en
Priority to HK02100334.3A priority patent/HK1039062A1/zh
Priority to PCT/IT1999/000251 priority patent/WO2000007581A2/en
Priority to KR1020017001339A priority patent/KR20010072146A/ko
Priority to JP2000563266A priority patent/JP2002522382A/ja
Priority to IL14079799A priority patent/IL140797A0/xx
Priority to CA002338035A priority patent/CA2338035A1/en
Priority to EEP200100052A priority patent/EE200100052A/xx
Priority to PL99346161A priority patent/PL346161A1/xx
Priority to BR9912703-2A priority patent/BR9912703A/pt
Priority to CN99809268A priority patent/CN1311674A/zh
Priority to TR2001/00333T priority patent/TR200100333T2/xx
Priority to TNTNSN99152A priority patent/TNSN99152A1/fr
Priority to MA25710A priority patent/MA26666A1/fr
Priority to ARP990103863A priority patent/AR021172A1/es
Publication of ITRM980516A1 publication Critical patent/ITRM980516A1/it
Application granted granted Critical
Publication of IT1302125B1 publication Critical patent/IT1302125B1/it
Priority to IS5816A priority patent/IS5816A/is
Priority to NO20010532A priority patent/NO20010532L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Microbiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Cardiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT1998RM000516A 1998-08-03 1998-08-03 Composizione ad attivita' antiossidante ed antiproliferativacomprendente una carnitina ed un carotenoide IT1302125B1 (it)

Priority Applications (21)

Application Number Priority Date Filing Date Title
IT1998RM000516A IT1302125B1 (it) 1998-08-03 1998-08-03 Composizione ad attivita' antiossidante ed antiproliferativacomprendente una carnitina ed un carotenoide
CA002338035A CA2338035A1 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
PL99346161A PL346161A1 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
AU50641/99A AU5064199A (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
EP99935044A EP1102584A2 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
HK02100334.3A HK1039062A1 (zh) 1998-08-03 1999-07-29 含有卡尼汀和類胡蘿卜素的抗氧劑、抗增殖組合物
PCT/IT1999/000251 WO2000007581A2 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
KR1020017001339A KR20010072146A (ko) 1998-08-03 1999-07-29 카르니틴 및 카로티노이드를 포함하는 산화 방지성 증식억제 조성물
JP2000563266A JP2002522382A (ja) 1998-08-03 1999-07-29 カルニチンおよびカロテノイドを含む抗酸化、抗増殖組成物
IL14079799A IL140797A0 (en) 1998-08-03 1999-07-29 Antioxidant, antiproliferous composition, comprising a carnitine and a carotenoid
HU0102807A HUP0102807A2 (hu) 1998-08-03 1999-07-29 Karnitint és karotenoidet tartalmazó antioxidáns, antiproliferációs készítmény
EEP200100052A EE200100052A (et) 1998-08-03 1999-07-29 Oksüdeerumisvastane, vohamisvastane kompositsioon, mis sisaldab karnitiini ning karotenoidi
SK125-2001A SK1252001A3 (en) 1998-08-03 1999-07-29 ANTIOXIDANT, ANTIPROLIFEROUS COMPOSITION, COMPRISING A CARNITINEì (54) AND A CAROTENOID
BR9912703-2A BR9912703A (pt) 1998-08-03 1999-07-29 Composição antioxidante, antiprolìfera, compreendendo uma carnitina e um carotenóide
CN99809268A CN1311674A (zh) 1998-08-03 1999-07-29 含有卡尼汀和类胡萝卜素的抗氧剂、抗增殖组合物
TR2001/00333T TR200100333T2 (tr) 1998-08-03 1999-07-29 Bir karnitin ve bir karotenoit içeren antioksidan, antiproliferos bileşim
TNTNSN99152A TNSN99152A1 (fr) 1998-08-03 1999-07-30 Composition antioxydante et antiproliferative comportant un carnitine et un carotenoide
MA25710A MA26666A1 (fr) 1998-08-03 1999-08-03 Antioxide, composition antiproliferee, y compris carnitine et carotenoide.
ARP990103863A AR021172A1 (es) 1998-08-03 1999-08-03 Composicion antiprolifica, antioxidante, que comprende una carnitina y un carotenoide
IS5816A IS5816A (is) 1998-08-03 2001-01-16 Andoxunarefni, andfjölgunarsamsetning, sem samanstendur af karnitíni og karótínóíði
NO20010532A NO20010532L (no) 1998-08-03 2001-01-31 Antioksidant, antiproliferativ sammensetning som innbefatter et karnitin og et karotenoid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998RM000516A IT1302125B1 (it) 1998-08-03 1998-08-03 Composizione ad attivita' antiossidante ed antiproliferativacomprendente una carnitina ed un carotenoide

Publications (3)

Publication Number Publication Date
ITRM980516A0 ITRM980516A0 (it) 1998-08-03
ITRM980516A1 ITRM980516A1 (it) 2000-02-03
IT1302125B1 true IT1302125B1 (it) 2000-07-31

Family

ID=11406082

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998RM000516A IT1302125B1 (it) 1998-08-03 1998-08-03 Composizione ad attivita' antiossidante ed antiproliferativacomprendente una carnitina ed un carotenoide

Country Status (21)

Country Link
EP (1) EP1102584A2 (it)
JP (1) JP2002522382A (it)
KR (1) KR20010072146A (it)
CN (1) CN1311674A (it)
AR (1) AR021172A1 (it)
AU (1) AU5064199A (it)
BR (1) BR9912703A (it)
CA (1) CA2338035A1 (it)
EE (1) EE200100052A (it)
HK (1) HK1039062A1 (it)
HU (1) HUP0102807A2 (it)
IL (1) IL140797A0 (it)
IS (1) IS5816A (it)
IT (1) IT1302125B1 (it)
MA (1) MA26666A1 (it)
NO (1) NO20010532L (it)
PL (1) PL346161A1 (it)
SK (1) SK1252001A3 (it)
TN (1) TNSN99152A1 (it)
TR (1) TR200100333T2 (it)
WO (1) WO2000007581A2 (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001091807A2 (en) 2000-06-02 2001-12-06 Board Of Regents Ethylenedicysteine (ec)-drug conjugates
US6923960B2 (en) 2001-10-03 2005-08-02 Vsl Pharmaceuticals Inc. Antioxidant combination composition and use thereof
KR100523562B1 (ko) 2001-10-29 2005-10-25 한국과학기술연구원 손바닥선인장 추출물 및 이로부터 분리된 화합물을함유하는 신경세포 보호용 조성물
JP4527938B2 (ja) * 2002-07-23 2010-08-18 オルビス株式会社 抗酸化用の経口投与組成物
JP4334189B2 (ja) * 2002-07-30 2009-09-30 カゴメ株式会社 Ａｇｅ生成阻害剤
ITRM20020620A1 (it) * 2002-12-13 2004-06-14 Sigma Tau Ind Farmaceuti Uso delle carnitine per la prevenzione e/o il trattamento dei disturbi causati dall'andropausa.
ES2320995T3 (es) 2003-04-14 2009-06-01 Nippon Soda Co., Ltd. Derivado de diamina, procedimiento de produccion y farmaco antioxidante.
US9050378B2 (en) 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
CN1917779B (zh) * 2004-01-28 2010-06-16 雀巢技术公司 用于改善皮肤状况和防止皮肤病的营养组合物
US8758723B2 (en) 2006-04-19 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
RU2619342C1 (ru) * 2016-02-24 2017-05-15 федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" Препарат для профилактики и лечения свободнорадикальной патологии у животных
CN113491687A (zh) * 2020-04-02 2021-10-12 常州高新技术产业开发区三维工业技术研究所有限公司 一种解毒药物组合物及其用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518617B2 (en) * 1977-04-29 1981-10-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Therapeutic application of acetyl-d, 1-carnitine
EP0400547A1 (en) * 1989-06-02 1990-12-05 Abbott Laboratories Parenteral nutrition product
IT1276225B1 (it) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per
IT1277953B1 (it) * 1995-12-21 1997-11-12 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per
IT1283967B1 (it) * 1996-03-29 1998-05-07 Sigma Tau Ind Farmaceuti Uso di l-carnitina o derivati della l-carnitina ed antiossidanti nella prevenzione e trattamento di patologie derivanti da danni ossidativi
US5667791A (en) * 1996-05-31 1997-09-16 Thione International, Inc. X-ray induced skin damage protective composition
US5895652A (en) * 1996-07-29 1999-04-20 Longevity Institute International Method of metabolic adjuvanation and cellular repair
CA2280093A1 (en) * 1997-02-04 1998-08-06 John V. Kosbab Compositions and methods for prevention and treatment of vascular degenerative diseases
IT1291113B1 (it) * 1997-03-20 1998-12-29 Sigma Tau Ind Farmaceuti Composizione nutritiva terapeutica per soggetti affetti da diabete mellito

Also Published As

Publication number Publication date
WO2000007581A2 (en) 2000-02-17
JP2002522382A (ja) 2002-07-23
KR20010072146A (ko) 2001-07-31
TR200100333T2 (tr) 2001-07-23
EE200100052A (et) 2002-06-17
AR021172A1 (es) 2002-07-03
MA26666A1 (fr) 2004-12-20
ITRM980516A0 (it) 1998-08-03
IS5816A (is) 2001-01-16
ITRM980516A1 (it) 2000-02-03
PL346161A1 (en) 2002-01-28
BR9912703A (pt) 2001-05-02
WO2000007581A3 (en) 2000-05-11
SK1252001A3 (en) 2001-08-06
CA2338035A1 (en) 2000-02-17
CN1311674A (zh) 2001-09-05
TNSN99152A1 (fr) 2005-11-10
IL140797A0 (en) 2002-02-10
HUP0102807A2 (hu) 2002-03-28
NO20010532D0 (no) 2001-01-31
HK1039062A1 (zh) 2002-04-12
EP1102584A2 (en) 2001-05-30
AU5064199A (en) 2000-02-28
NO20010532L (no) 2001-03-20

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