IT1238675B - Anticorpo monoclonale in grado di riconoscere uno specifico epitopo di glicosidi antraciclinici e ibridoma secernente tale anticorpo - Google Patents
Anticorpo monoclonale in grado di riconoscere uno specifico epitopo di glicosidi antraciclinici e ibridoma secernente tale anticorpoInfo
- Publication number
- IT1238675B IT1238675B IT19160A IT1916090A IT1238675B IT 1238675 B IT1238675 B IT 1238675B IT 19160 A IT19160 A IT 19160A IT 1916090 A IT1916090 A IT 1916090A IT 1238675 B IT1238675 B IT 1238675B
- Authority
- IT
- Italy
- Prior art keywords
- antibody
- monoclonal antibody
- anthracyclinic
- hybridome
- seconding
- Prior art date
Links
- 229930182470 glycoside Natural products 0.000 title 1
- 150000002338 glycosides Chemical class 0.000 title 1
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 abstract 2
- 229940045799 anthracyclines and related substance Drugs 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229960004679 doxorubicin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT19160A IT1238675B (it) | 1990-01-26 | 1990-01-26 | Anticorpo monoclonale in grado di riconoscere uno specifico epitopo di glicosidi antraciclinici e ibridoma secernente tale anticorpo |
| DK91100426.5T DK0439048T3 (da) | 1990-01-26 | 1991-01-16 | Monoklonalt antistof, som genkender en anthracyclinglycosidspecifik epitop, og hybridoma, der udskiller dette antistof |
| EP91100426A EP0439048B1 (en) | 1990-01-26 | 1991-01-16 | Monoclonal antibody recognizing anthracycline glycoside specific epitope and hybridoma secerning said antibody |
| ES91100426T ES2082017T3 (es) | 1990-01-26 | 1991-01-16 | Anticuerpo monoclonal que reconoce el epitopo especifico de glucosidos de antraciclina e hibridoma que secreta dicho anticuerpo. |
| DE69115938T DE69115938T2 (de) | 1990-01-26 | 1991-01-16 | Monoklonaler Antikörper zur Erkennung eines Anthracyclinglycosid-spezifischen Epitopes und diesen Antikörper herstellendes Hybridoma |
| AT91100426T ATE132536T1 (de) | 1990-01-26 | 1991-01-16 | Monoklonaler antikörper zur erkennung eines anthracyclinglycosid-spezifischen epitopes und diesen antikörper herstellendes hybridoma |
| US07/642,024 US5177016A (en) | 1990-01-26 | 1991-01-16 | Monoclonal antibody recognizing anthracycline glycoside specific epitope and hybridoma secerning the antibody |
| JP3023910A JP3014781B2 (ja) | 1990-01-26 | 1991-01-24 | アンスラサイクリン配糖体に特異的なエピトープを認識するモノクローナル抗体とその抗体を分泌するハイブリドーマ |
| GR960400763T GR3019363T3 (en) | 1990-01-26 | 1996-03-19 | Monoclonal antibody recognizing anthracycline glycoside specific epitope and hybridoma secerning said antibody |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT19160A IT1238675B (it) | 1990-01-26 | 1990-01-26 | Anticorpo monoclonale in grado di riconoscere uno specifico epitopo di glicosidi antraciclinici e ibridoma secernente tale anticorpo |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT9019160A0 IT9019160A0 (it) | 1990-01-26 |
| IT9019160A1 IT9019160A1 (it) | 1991-07-27 |
| IT1238675B true IT1238675B (it) | 1993-09-01 |
Family
ID=11155391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT19160A IT1238675B (it) | 1990-01-26 | 1990-01-26 | Anticorpo monoclonale in grado di riconoscere uno specifico epitopo di glicosidi antraciclinici e ibridoma secernente tale anticorpo |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5177016A (it) |
| EP (1) | EP0439048B1 (it) |
| JP (1) | JP3014781B2 (it) |
| AT (1) | ATE132536T1 (it) |
| DE (1) | DE69115938T2 (it) |
| DK (1) | DK0439048T3 (it) |
| ES (1) | ES2082017T3 (it) |
| GR (1) | GR3019363T3 (it) |
| IT (1) | IT1238675B (it) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6231855B1 (en) * | 1991-03-12 | 2001-05-15 | Istituto Nazionale Per Lo Studio E La Cura Dei Tumori | Monoclonal antibodies as antidotes for anthracycline antibiotics |
| DE602006015929D1 (de) * | 2005-03-30 | 2010-09-16 | Saladax Biomedical Inc | Doxorubicin-immuntest |
| WO2009038770A2 (en) * | 2007-09-20 | 2009-03-26 | University Of Massachusetts Cvip | Detoxified recombinant botulinum neurotoxin |
| WO2014080251A1 (en) | 2012-11-24 | 2014-05-30 | Hangzhou Dac Biotech Co., Ltd. | Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules |
| PT3122757T (pt) | 2014-02-28 | 2023-11-03 | Hangzhou Dac Biotech Co Ltd | Ligantes carregados e as suas utilizações em conjugação |
| CN108449940B (zh) | 2015-07-12 | 2021-06-08 | 杭州多禧生物科技有限公司 | 与细胞结合分子的共轭偶联的桥连接体 |
| US9839687B2 (en) | 2015-07-15 | 2017-12-12 | Suzhou M-Conj Biotech Co., Ltd. | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule |
| CN110099682B (zh) | 2016-11-14 | 2023-03-31 | 杭州多禧生物科技有限公司 | 偶联连接体,含有此连接体的细胞结合分子-药物偶联物及其制备和应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1223136B (it) * | 1987-11-17 | 1990-09-12 | Ist Naz Stud Cura Dei Tumori | Anticorpi monoclonali capaci di legarsi selettivamente alla doxorubicina ed analoghi e derivati |
-
1990
- 1990-01-26 IT IT19160A patent/IT1238675B/it active IP Right Grant
-
1991
- 1991-01-16 DE DE69115938T patent/DE69115938T2/de not_active Expired - Fee Related
- 1991-01-16 US US07/642,024 patent/US5177016A/en not_active Expired - Lifetime
- 1991-01-16 AT AT91100426T patent/ATE132536T1/de not_active IP Right Cessation
- 1991-01-16 DK DK91100426.5T patent/DK0439048T3/da active
- 1991-01-16 EP EP91100426A patent/EP0439048B1/en not_active Expired - Lifetime
- 1991-01-16 ES ES91100426T patent/ES2082017T3/es not_active Expired - Lifetime
- 1991-01-24 JP JP3023910A patent/JP3014781B2/ja not_active Expired - Fee Related
-
1996
- 1996-03-19 GR GR960400763T patent/GR3019363T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0439048B1 (en) | 1996-01-03 |
| ATE132536T1 (de) | 1996-01-15 |
| DE69115938T2 (de) | 1996-05-15 |
| EP0439048A2 (en) | 1991-07-31 |
| EP0439048A3 (en) | 1991-09-11 |
| DK0439048T3 (da) | 1996-05-13 |
| JPH08295699A (ja) | 1996-11-12 |
| ES2082017T3 (es) | 1996-03-16 |
| JP3014781B2 (ja) | 2000-02-28 |
| IT9019160A0 (it) | 1990-01-26 |
| GR3019363T3 (en) | 1996-06-30 |
| IT9019160A1 (it) | 1991-07-27 |
| US5177016A (en) | 1993-01-05 |
| DE69115938D1 (de) | 1996-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960130 |