[go: up one dir, main page]

IT1230145B - Complessi di rutenio (iii) come agenti antineoplastici. - Google Patents

Complessi di rutenio (iii) come agenti antineoplastici.

Info

Publication number
IT1230145B
IT1230145B IT8920385A IT2038589A IT1230145B IT 1230145 B IT1230145 B IT 1230145B IT 8920385 A IT8920385 A IT 8920385A IT 2038589 A IT2038589 A IT 2038589A IT 1230145 B IT1230145 B IT 1230145B
Authority
IT
Italy
Prior art keywords
pct
complexes
ruthenium
iii
antineoplastic agents
Prior art date
Application number
IT8920385A
Other languages
English (en)
Other versions
IT8920385A0 (it
Inventor
Enzo Alessio
Giovanni Mestroni
Sabrina Pacor
Gianni Sava
Silvano Spinelli
Original Assignee
Boehringer Biochemia Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Biochemia Srl filed Critical Boehringer Biochemia Srl
Priority to IT8920385A priority Critical patent/IT1230145B/it
Publication of IT8920385A0 publication Critical patent/IT8920385A0/it
Priority to ES90906961T priority patent/ES2064729T3/es
Priority to DE69014619T priority patent/DE69014619T2/de
Priority to AT90906961T priority patent/ATE114663T1/de
Priority to PCT/EP1990/000699 priority patent/WO1990013553A1/en
Priority to US07/773,939 priority patent/US5409893A/en
Priority to EP90906961A priority patent/EP0471709B1/en
Priority to AU55302/90A priority patent/AU629341B2/en
Application granted granted Critical
Publication of IT1230145B publication Critical patent/IT1230145B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT8920385A 1989-05-05 1989-05-05 Complessi di rutenio (iii) come agenti antineoplastici. IT1230145B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT8920385A IT1230145B (it) 1989-05-05 1989-05-05 Complessi di rutenio (iii) come agenti antineoplastici.
ES90906961T ES2064729T3 (es) 1989-05-05 1990-05-02 Complejos de rutenio (iii) como agentes antineoplasticos.
DE69014619T DE69014619T2 (de) 1989-05-05 1990-05-02 Ruthenium(iii)-komplexe als antineoplastische mittel.
AT90906961T ATE114663T1 (de) 1989-05-05 1990-05-02 Ruthenium(iii)-komplexe als antineoplastische mittel.
PCT/EP1990/000699 WO1990013553A1 (en) 1989-05-05 1990-05-02 Ruthenium(iii) complexes as antineoplastic agents
US07/773,939 US5409893A (en) 1989-05-05 1990-05-02 Ruthenium(III) complexes as antineoplastic agents
EP90906961A EP0471709B1 (en) 1989-05-05 1990-05-02 Ruthenium(iii) complexes as antineoplastic agents
AU55302/90A AU629341B2 (en) 1989-05-05 1990-05-02 Ruthenium(iii) complexes as antineoplastic agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920385A IT1230145B (it) 1989-05-05 1989-05-05 Complessi di rutenio (iii) come agenti antineoplastici.

Publications (2)

Publication Number Publication Date
IT8920385A0 IT8920385A0 (it) 1989-05-05
IT1230145B true IT1230145B (it) 1991-10-14

Family

ID=11166245

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8920385A IT1230145B (it) 1989-05-05 1989-05-05 Complessi di rutenio (iii) come agenti antineoplastici.

Country Status (8)

Country Link
US (1) US5409893A (it)
EP (1) EP0471709B1 (it)
AT (1) ATE114663T1 (it)
AU (1) AU629341B2 (it)
DE (1) DE69014619T2 (it)
ES (1) ES2064729T3 (it)
IT (1) IT1230145B (it)
WO (1) WO1990013553A1 (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9317686D0 (en) * 1993-08-25 1993-10-13 Johnson Matthey Plc Pharmaceutical compositions
IT1284101B1 (it) * 1996-07-02 1998-05-08 Sigea Srl Sali di complessi anionici di ru(iii), utili in terapia come agenti antimetastatici e antineoplastici
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
GB0028025D0 (en) * 2000-11-17 2001-01-03 Univ York Compounds
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
CA2789262C (en) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Pharma-informatics system
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
JP5296063B2 (ja) * 2007-06-11 2013-09-25 ニッキ ファーマ インク． ルテニウム錯体を製造する方法
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
PT2509599E (pt) * 2009-12-11 2014-10-15 Niiki Pharma Inc Processo para o tratamento de cancro pancreático
JP6034288B2 (ja) * 2010-07-18 2016-11-30 ニーキ ファーマ インコーポレイテッド ルテニウム錯体を用いる併用療法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN103665046A (zh) * 2012-08-31 2014-03-26 澳门科技大学 钌配合物及其制备方法和应用
CN104744518B (zh) * 2015-02-11 2018-08-07 中国中医科学院中药研究所 金属钌配合物及其制备方法和应用
CN115028665B (zh) * 2022-06-06 2023-12-26 山西大学 一种以手性甲硫氨酸和5-氯-8-羟基喹啉为配体的亚硝酰钌配合物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3557143A (en) * 1967-08-30 1971-01-19 Colgate Palmolive Co Bridged bicyclic ferrocene ethers and thioethers
US3576012A (en) * 1967-11-02 1971-04-20 Hercules Inc Nickel salts of iminoheterocyclicamides

Also Published As

Publication number Publication date
US5409893A (en) 1995-04-25
IT8920385A0 (it) 1989-05-05
AU5530290A (en) 1990-11-29
DE69014619D1 (de) 1995-01-12
DE69014619T2 (de) 1995-05-18
EP0471709B1 (en) 1994-11-30
EP0471709A1 (en) 1992-02-26
WO1990013553A1 (en) 1990-11-15
ATE114663T1 (de) 1994-12-15
ES2064729T3 (es) 1995-02-01
AU629341B2 (en) 1992-10-01

Similar Documents

Publication Publication Date Title
IT1230145B (it) Complessi di rutenio (iii) come agenti antineoplastici.
ATE225341T1 (de) In 6-position durch thio substituierte paclitaxele
NO960754L (no) Farmasöytiske blandinger omfattende metall-komplekser
GR3017282T3 (en) Novel arylpyridazines, their manufacture, use and medicaments containing them.
DE69407594D1 (de) Spielzeugbausatz und bauelemente dafür
ID28003A (id) Turunan-turunan adamantana
NO972459D0 (no) Nye flersubst DTPA-derivater og deres metallkomplekser, farmasöytiske preparater inneh slike komplekser, deres anv ved diagnostikk og terapi, fremg for fremst av de kompleksdannende midler og komplekser, samt fremg for frems av de farmasöytiske
DE69005359D1 (de) Poröse Einheitsform und Verfahren.
CA2114136A1 (en) Gallium (iii) complexes, process for their obtention and pharmaceutical compositions containing them
AU4484989A (en) Water soluble 1,2-diaminocyclohexane platinum (iv) complexes as antitumor agents
IL118670A (en) Enantiomerically pure bisphosphines their preparation metal complexes and their use
DE3579730D1 (de) Eisen-3-hydroxypyron- oder 3-hydroxypyridon-komplexe und diese enthaltende pharmazeutische zusammensetzungen.
ATE69233T1 (de) (2,2-bis(aminomethyl)-1,3-propandiol-n,n'>plati - komplexe.
DK0701440T3 (da) Tri(platin)komplekser
ITMI940610A0 (it) Platino complessi cationici trinucleari ad attivita' antitumorale e composizioni farmaceutiche che li contengono
FR2675996B1 (fr) Compositions sanogenes dietetiques complexes.
DE69107533D1 (de) 2,2'-Bis(dicyclopentylphosphino)-1,1'-binaphthyl und Metallkomplexe davon.
NO894594L (no) Farmasoeytiske sammensetninger omfattende labdan diterpenoid-derivater og pyrimido(6,1-a)isoquinolin-4-one-derivater.
DE60133491D1 (de) Zusammensetzung mit demethylcantharidin in kombination mit platinhaltigen antikrebsmitteln und ihre verwendung
CA2205868A1 (en) Trinuclear cationic platinum complexes having antitumour activity and pharmaceutical compositions containing them
DE3880991D1 (de) Aminoanthracendion-bis-platinkomplexe, nuetzlich als antitumor-agenzien.
NO900564L (no) Overflateaktivt middel.
ITMI20020993A1 (it) Complessi di platino ad attivita' antitumorale
ATE161899T1 (de) Komplexverbindungen mit oligomerem bis polymerem charakter
ES2032209T3 (es) Derivados de proteinas que contienen hierro en forma altamente biodisponible, su preparacion y composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970530