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IT1296439B1 - GENETICALLY MODIFIED MYOGENIC PRECURSORS AND THEIR USE IN GENE AND CELL THERAPY - Google Patents

GENETICALLY MODIFIED MYOGENIC PRECURSORS AND THEIR USE IN GENE AND CELL THERAPY

Info

Publication number
IT1296439B1
IT1296439B1 IT97MI002542A ITMI972542A IT1296439B1 IT 1296439 B1 IT1296439 B1 IT 1296439B1 IT 97MI002542 A IT97MI002542 A IT 97MI002542A IT MI972542 A ITMI972542 A IT MI972542A IT 1296439 B1 IT1296439 B1 IT 1296439B1
Authority
IT
Italy
Prior art keywords
gene
genetically modified
cell therapy
myogenic precursors
modified myogenic
Prior art date
Application number
IT97MI002542A
Other languages
Italian (it)
Inventor
Fulvio Mavilio
Original Assignee
San Raffaele Centro Fond
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by San Raffaele Centro Fond filed Critical San Raffaele Centro Fond
Priority to IT97MI002542A priority Critical patent/IT1296439B1/en
Priority to PCT/EP1998/007263 priority patent/WO1999025814A1/en
Priority to AU18725/99A priority patent/AU1872599A/en
Priority to CA002310016A priority patent/CA2310016A1/en
Priority to JP2000521180A priority patent/JP2001523448A/en
Priority to EP98963450A priority patent/EP1030908A1/en
Publication of ITMI972542A1 publication Critical patent/ITMI972542A1/en
Application granted granted Critical
Publication of IT1296439B1 publication Critical patent/IT1296439B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT97MI002542A 1997-11-14 1997-11-14 GENETICALLY MODIFIED MYOGENIC PRECURSORS AND THEIR USE IN GENE AND CELL THERAPY IT1296439B1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT97MI002542A IT1296439B1 (en) 1997-11-14 1997-11-14 GENETICALLY MODIFIED MYOGENIC PRECURSORS AND THEIR USE IN GENE AND CELL THERAPY
PCT/EP1998/007263 WO1999025814A1 (en) 1997-11-14 1998-11-13 Genetically-modified myogenic progenitors and their use in cell and gene therapy
AU18725/99A AU1872599A (en) 1997-11-14 1998-11-13 Genetically-modified myogenic progenitors and their use in cell and gene therapy
CA002310016A CA2310016A1 (en) 1997-11-14 1998-11-13 Genetically-modified myogenic progenitors and their use in cell and gene therapy
JP2000521180A JP2001523448A (en) 1997-11-14 1998-11-13 Genetically modified myogenic precursors and their use in cells and gene therapy
EP98963450A EP1030908A1 (en) 1997-11-14 1998-11-13 Genetically-modified myogenic progenitors and their use in cell and gene therapy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI002542A IT1296439B1 (en) 1997-11-14 1997-11-14 GENETICALLY MODIFIED MYOGENIC PRECURSORS AND THEIR USE IN GENE AND CELL THERAPY

Publications (2)

Publication Number Publication Date
ITMI972542A1 ITMI972542A1 (en) 1999-05-14
IT1296439B1 true IT1296439B1 (en) 1999-06-25

Family

ID=11378206

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97MI002542A IT1296439B1 (en) 1997-11-14 1997-11-14 GENETICALLY MODIFIED MYOGENIC PRECURSORS AND THEIR USE IN GENE AND CELL THERAPY

Country Status (6)

Country Link
EP (1) EP1030908A1 (en)
JP (1) JP2001523448A (en)
AU (1) AU1872599A (en)
CA (1) CA2310016A1 (en)
IT (1) IT1296439B1 (en)
WO (1) WO1999025814A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2386536A1 (en) * 1999-09-14 2001-03-22 The Children's Medical Center Corporation Methods for treating muscular dystrophy with bone marrow cells
WO2005120526A1 (en) * 2004-06-11 2005-12-22 Combi Corporation Composition for inhibiting the progress of muscular dystrophy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7312891A (en) * 1990-02-12 1991-09-03 Board Of Regents, The University Of Texas System Satellite cell proliferation in adult skeletal muscle
US5591625A (en) * 1993-11-24 1997-01-07 Case Western Reserve University Transduced mesenchymal stem cells
GB9419048D0 (en) * 1994-09-20 1994-11-09 Watt Diana J Treatment of muscular disorders
AU706026B2 (en) * 1995-06-06 1999-06-10 Case Western Reserve University Myogenic differentiation of human mesenchymal stem cells

Also Published As

Publication number Publication date
WO1999025814B1 (en) 1999-07-22
CA2310016A1 (en) 1999-05-27
JP2001523448A (en) 2001-11-27
ITMI972542A1 (en) 1999-05-14
WO1999025814A1 (en) 1999-05-27
EP1030908A1 (en) 2000-08-30
AU1872599A (en) 1999-06-07

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Legal Events

Date Code Title Description
0001 Granted