IT1277597B1 - Derivati di diarilalchenilammina - Google Patents

Derivati di diarilalchenilammina

Info

Publication number: IT1277597B1
Authority: IT; Italy
Prior art keywords: diarylalkenylamine; derivatives; diarylalkenylamine derivatives
Prior art date: 1995-09-15

Application number

IT95MI001930A

Other languages

English (en)

Inventor

Giulio Dondio

Silvano Ronzoni

Original Assignee

Smithkline Beecham Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-15

Filing date

1995-09-15

Publication date

1997-11-11

1995-09-15 Application filed by Smithkline Beecham Spa filed Critical Smithkline Beecham Spa

1995-09-15 Publication of ITMI951930A0 publication Critical patent/ITMI951930A0/it

1995-09-15 Priority to IT95MI001930A priority Critical patent/IT1277597B1/it

1996-09-09 Priority to HU9900374A priority patent/HUP9900374A3/hu

1996-09-09 Priority to AT96931791T priority patent/ATE240307T1/de

1996-09-09 Priority to DE69628200T priority patent/DE69628200T2/de

1996-09-09 Priority to ES96931791T priority patent/ES2195010T3/es

1996-09-09 Priority to AU70847/96A priority patent/AU706980B2/en

1996-09-09 Priority to JP9511657A priority patent/JPH11512413A/ja

1996-09-09 Priority to EP96931791A priority patent/EP0873330B1/en

1996-09-09 Priority to KR1019980701930A priority patent/KR19990044675A/ko

1996-09-09 Priority to PCT/EP1996/003988 priority patent/WO1997010230A1/en

1996-09-09 Priority to TR1998/00478T priority patent/TR199800478T1/xx

1996-09-09 Priority to CN96198240A priority patent/CN1202164A/zh

1996-09-09 Priority to IL12362196A priority patent/IL123621A0/xx

1996-09-09 Priority to BR9610597A priority patent/BR9610597A/pt

1996-09-09 Priority to CZ98785A priority patent/CZ78598A3/cs

1996-09-09 Priority to PL96325552A priority patent/PL325552A1/xx

1996-09-09 Priority to CA002232161A priority patent/CA2232161A1/en

1996-09-09 Priority to NZ318774A priority patent/NZ318774A/en

1996-09-09 Priority to US09/029,892 priority patent/US6262104B1/en

1996-09-12 Priority to ARP960104332A priority patent/AR004205A1/es

1996-09-13 Priority to ZA9607741A priority patent/ZA967741B/xx

1997-03-15 Publication of ITMI951930A1 publication Critical patent/ITMI951930A1/it

1997-11-11 Application granted granted Critical

1997-11-11 Publication of IT1277597B1 publication Critical patent/IT1277597B1/it

1998-03-13 Priority to NO981131A priority patent/NO981131L/no

1998-03-13 Priority to MXPA/A/1998/002024A priority patent/MXPA98002024A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Transplantation (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IT95MI001930A 1995-09-15 1995-09-15 Derivati di diarilalchenilammina IT1277597B1 (it)

Priority Applications (23)

Application Number	Priority Date	Filing Date	Title
IT95MI001930A IT1277597B1 (it)	1995-09-15	1995-09-15	Derivati di diarilalchenilammina
IL12362196A IL123621A0 (en)	1995-09-15	1996-09-09	Diarylalkenylamine derivatives
CZ98785A CZ78598A3 (cs)	1995-09-15	1996-09-09	Diarylalkenylaminové deriváty, farmaceutické prostředky s jejich obsahem, použití a způsob
DE69628200T DE69628200T2 (de)	1995-09-15	1996-09-09	Diarylalkenylamin-derivate
ES96931791T ES2195010T3 (es)	1995-09-15	1996-09-09	Derivados de di-arilalquenilaminas.
AU70847/96A AU706980B2 (en)	1995-09-15	1996-09-09	Diarylalkenylamine derivatives
JP9511657A JPH11512413A (ja)	1995-09-15	1996-09-09	ジアリールアルケニルアミン誘導体
EP96931791A EP0873330B1 (en)	1995-09-15	1996-09-09	Diarylalkenylamine derivatives
KR1019980701930A KR19990044675A (ko)	1995-09-15	1996-09-09	디아릴알케닐아민 유도체
PCT/EP1996/003988 WO1997010230A1 (en)	1995-09-15	1996-09-09	Diarylalkenylamine derivatives
TR1998/00478T TR199800478T1 (xx)	1995-09-15	1996-09-09	Diarilalkenilamin t�revleri
CN96198240A CN1202164A (zh)	1995-09-15	1996-09-09	二芳基链烯基胺衍生物
HU9900374A HUP9900374A3 (en)	1995-09-15	1996-09-09	Diarylalkenylamine derivatives and pharmaceutical compns. contg. them
BR9610597A BR9610597A (pt)	1995-09-15	1996-09-09	Derivados de diarilalcenilamina
AT96931791T ATE240307T1 (de)	1995-09-15	1996-09-09	Diarylalkenylamin-derivate
PL96325552A PL325552A1 (en)	1995-09-15	1996-09-09	Derivatives of diaryl alkenylamine
CA002232161A CA2232161A1 (en)	1995-09-15	1996-09-09	Diarylalkenylamine derivatives
NZ318774A NZ318774A (en)	1995-09-15	1996-09-09	Dialkyl-substituted benzamides
US09/029,892 US6262104B1 (en)	1995-09-15	1996-09-09	Diarylalkenylamine derivatives
ARP960104332A AR004205A1 (es)	1995-09-15	1996-09-12	Derivados de diarilalquenilaminas, composiciones farmaceuticas que las contienen y el uso de dichos derivados en la preparacion de medicamentos.
ZA9607741A ZA967741B (en)	1995-09-15	1996-09-13	Diarylalkenylamine derivatives.
NO981131A NO981131L (no)	1995-09-15	1998-03-13	Diarylalkenylamin-derivater
MXPA/A/1998/002024A MXPA98002024A (en)	1995-09-15	1998-03-13	Derivatives of diarilalquenilam

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT95MI001930A IT1277597B1 (it)	1995-09-15	1995-09-15	Derivati di diarilalchenilammina

Publications (3)

Publication Number	Publication Date
ITMI951930A0 ITMI951930A0 (it)	1995-09-15
ITMI951930A1 ITMI951930A1 (it)	1997-03-15
IT1277597B1 true IT1277597B1 (it)	1997-11-11

Family

ID=11372254

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT95MI001930A IT1277597B1 (it)	1995-09-15	1995-09-15	Derivati di diarilalchenilammina

Country Status (22)

Country	Link
US (1)	US6262104B1 (it)
EP (1)	EP0873330B1 (it)
JP (1)	JPH11512413A (it)
KR (1)	KR19990044675A (it)
CN (1)	CN1202164A (it)
AR (1)	AR004205A1 (it)
AT (1)	ATE240307T1 (it)
AU (1)	AU706980B2 (it)
BR (1)	BR9610597A (it)
CA (1)	CA2232161A1 (it)
CZ (1)	CZ78598A3 (it)
DE (1)	DE69628200T2 (it)
ES (1)	ES2195010T3 (it)
HU (1)	HUP9900374A3 (it)
IL (1)	IL123621A0 (it)
IT (1)	IT1277597B1 (it)
NO (1)	NO981131L (it)
NZ (1)	NZ318774A (it)
PL (1)	PL325552A1 (it)
TR (1)	TR199800478T1 (it)
WO (1)	WO1997010230A1 (it)
ZA (1)	ZA967741B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5985880A (en) *	1996-06-05	1999-11-16	Delta Pharmaceuticals	Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds
US6103722A (en) *	1997-07-23	2000-08-15	The Medical College Of Wisconsin Research Foundation Inc.	Ischemic preconditioning
AU2009799A (en) *	1997-12-24	1999-07-19	Ortho-Mcneil Pharmaceutical, Inc.	4-(aryl(piperidin-4-yl)) aminobenzamides which bind to the delta-opioid receptor
US6436959B1 (en)	1998-12-23	2002-08-20	Ortho-Mcneil Pharmaceutical, Inc.	4-[aryl(piperidin-4-yl)]aminobenzamides
AU3231901A (en)	2000-02-18	2001-08-27	Meiji Seika Kaisha	Phenoxyalkylamine derivatives useful as opioid delta receptor agonists
US6790854B2 (en)	2000-03-24	2004-09-14	Meiji Seika Kaisha, Ltd.	Diphenylalkylamine derivatives useful as opioid receptor agonists
JP4667384B2 (ja)	2003-10-07	2011-04-13	レノビス，インコーポレイテッド	イオンチャネルリガンドとしてのアミド誘導体および薬学的組成物、ならびにこれらを使用する方法
WO2006023757A2 (en) *	2004-08-19	2006-03-02	University Of Virginia Patent Foundation	Novel tricyclic, bicyclic, monocyclic, and acyclic amines as potent sodium channel blocking agents
CA2580694A1 (en) *	2004-09-23	2006-03-30	Alexander Michalow	Methods for regulating neurotransmitter systems by inducing counteradaptations
US20080045610A1 (en) *	2004-09-23	2008-02-21	Alexander Michalow	Methods for regulating neurotransmitter systems by inducing counteradaptations
US20080300243A1 (en) *	2005-02-28	2008-12-04	Kelly Michael G	Amide Derivatives as Ion-Channel Ligands and Pharmaceutical Compositions and Methods of Using the Same
US7576099B2 (en)	2005-02-28	2009-08-18	Renovis, Inc.	Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0000322B1 (en)	1977-07-04	1982-05-05	Astra Läkemedel Aktiebolag	Compounds having an anti-depressive or tranquilizing activity, pharmaceutical compositions containing them, and processes and intermediates for their preparation
YU44821B (en)	1982-02-04	1991-02-28	Wellcome Found	Process for obtaiing new pyridyl derivatives
US4514414A (en) *	1982-10-25	1985-04-30	Smithkline Beckman Corporation	N-Substituted pyrrolidineacetic acids and their esters
US4564685A (en)	1983-03-10	1986-01-14	Findlay John W A	Diphenylmethane compounds
EP0219756B1 (de) *	1985-10-09	1994-01-05	Shell Internationale Researchmaatschappij B.V.	Neue Acrylsäureamide
DK0409406T3 (da)	1989-06-19	1994-02-07	Wellcome Found	Arylsubstituerede aminderivater, der er anvendelige ved cancerterapi

1995
- 1995-09-15 IT IT95MI001930A patent/IT1277597B1/it active IP Right Grant
1996
- 1996-09-09 WO PCT/EP1996/003988 patent/WO1997010230A1/en not_active Ceased
- 1996-09-09 IL IL12362196A patent/IL123621A0/xx unknown
- 1996-09-09 CA CA002232161A patent/CA2232161A1/en not_active Abandoned
- 1996-09-09 ES ES96931791T patent/ES2195010T3/es not_active Expired - Lifetime
- 1996-09-09 TR TR1998/00478T patent/TR199800478T1/xx unknown
- 1996-09-09 JP JP9511657A patent/JPH11512413A/ja not_active Withdrawn
- 1996-09-09 AT AT96931791T patent/ATE240307T1/de not_active IP Right Cessation
- 1996-09-09 PL PL96325552A patent/PL325552A1/xx unknown
- 1996-09-09 BR BR9610597A patent/BR9610597A/pt unknown
- 1996-09-09 HU HU9900374A patent/HUP9900374A3/hu unknown
- 1996-09-09 NZ NZ318774A patent/NZ318774A/en unknown
- 1996-09-09 CZ CZ98785A patent/CZ78598A3/cs unknown
- 1996-09-09 CN CN96198240A patent/CN1202164A/zh active Pending
- 1996-09-09 AU AU70847/96A patent/AU706980B2/en not_active Ceased
- 1996-09-09 EP EP96931791A patent/EP0873330B1/en not_active Expired - Lifetime
- 1996-09-09 KR KR1019980701930A patent/KR19990044675A/ko not_active Withdrawn
- 1996-09-09 US US09/029,892 patent/US6262104B1/en not_active Expired - Fee Related
- 1996-09-09 DE DE69628200T patent/DE69628200T2/de not_active Expired - Fee Related
- 1996-09-12 AR ARP960104332A patent/AR004205A1/es unknown
- 1996-09-13 ZA ZA9607741A patent/ZA967741B/xx unknown
1998
- 1998-03-13 NO NO981131A patent/NO981131L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AR004205A1 (es)	1998-11-04
MX9802024A (es)	1998-08-30
EP0873330B1 (en)	2003-05-14
CN1202164A (zh)	1998-12-16
DE69628200T2 (de)	2003-11-27
JPH11512413A (ja)	1999-10-26
IL123621A0 (en)	1998-10-30
TR199800478T1 (xx)	1998-06-22
CA2232161A1 (en)	1997-03-20
HUP9900374A2 (hu)	1999-06-28
US6262104B1 (en)	2001-07-17
NO981131D0 (no)	1998-03-13
AU7084796A (en)	1997-04-01
ATE240307T1 (de)	2003-05-15
KR19990044675A (ko)	1999-06-25
NZ318774A (en)	1998-08-26
ITMI951930A0 (it)	1995-09-15
EP0873330A1 (en)	1998-10-28
PL325552A1 (en)	1998-08-03
NO981131L (no)	1998-03-16
DE69628200D1 (de)	2003-06-18
AU706980B2 (en)	1999-07-01
WO1997010230A1 (en)	1997-03-20
HUP9900374A3 (en)	1999-11-29
BR9610597A (pt)	1999-07-06
CZ78598A3 (cs)	1998-08-12
ITMI951930A1 (it)	1997-03-15
ZA967741B (en)	1998-03-13
ES2195010T3 (es)	2003-12-01

Publication	Publication Date	Title
DE69611361D1 (de)	2001-02-01	Chinazolin-derivate
DE69522717D1 (de)	2001-10-18	Chinazolinderivate
NO974103D0 (no)	1997-09-05	Arylsulfonylaminohydroksamsyre-derivater
DE69610698D1 (de)	2000-11-23	Chinazolin-derivate
ITMI951020A0 (it)	1995-05-19	Derivati di diarildiammine
ATE199150T1 (de)	2001-02-15	Diphenylmethylenpiperidin-derivate
NO964667D0 (no)	1996-11-05	Purin-6-on-derivater
DE69601527D1 (de)	1999-03-25	Pyrrolylbenzimidazol-Derivate
ATA100695A (de)	1998-03-15	Prothrombin-derivate
IT1277073B1 (it)	1997-11-04	Derivati antraciclinici
IT1277597B1 (it)	1997-11-11	Derivati di diarilalchenilammina
ITMI951900A0 (it)	1995-09-12	Derivati idroisochinolinici sostituiti
DE69627830D1 (de)	2003-06-05	Pyrazol-derivate
DE59607054D1 (de)	2001-07-19	4-Amino-benzoylguanidin-Derivate
DE59610106D1 (de)	2003-03-13	Fluorbenzylether-Derivate
ATE177102T1 (de)	1999-03-15	Chromanderivate
DE69624122D1 (de)	2002-11-07	Aza-anthracyclinone-derivate
ITMI941191A0 (it)	1994-06-08	1-b-metil-2-tiol carbapen derivati
DE59607055D1 (de)	2001-07-19	4-Mercapto-benzoylguanidin-Derivate
ATA45796A (de)	1999-09-15	Lysin-prolin-derivate
IT1276169B1 (it)	1997-10-27	Derivati chinolinici
IT1276168B1 (it)	1997-10-27	Derivati chinolinici
IT1293559B1 (it)	1999-03-01	Derivati chinolinici
ITMI940202A0 (it)	1994-02-04	Derivati di idroisochinolina
ITMI940203A0 (it)	1994-02-04	Derivati di idroisochinolina

Legal Events

Date	Code	Title	Description
1997-11-11	0001	Granted